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  1. Article: Bilateral hibernomas in the femoral regions of a dog.

    Hifumi, Tatsuro / Inokuchi, Yoshinori / Tsujio, Masashi / Tanaka, Shogo / Hirano, Shinji / Miyoshi, Noriaki

    The Canadian veterinary journal = La revue veterinaire canadienne

    2024  Volume 65, Issue 4, Page(s) 367–370

    Abstract: A 14-year-old intact male Chihuahua dog was presented with masses located between ... ...

    Abstract A 14-year-old intact male Chihuahua dog was presented with masses located between the
    MeSH term(s) Male ; Dogs ; Animals ; Lipoma/diagnosis ; Lipoma/surgery ; Lipoma/veterinary ; Muscle, Skeletal/pathology ; Diagnosis, Differential ; Hindlimb/pathology ; Dog Diseases/diagnosis ; Dog Diseases/surgery ; Dog Diseases/pathology
    Language English
    Publishing date 2024-03-27
    Publishing country Canada
    Document type Case Reports
    ZDB-ID 41603-4
    ISSN 0008-5286
    ISSN 0008-5286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 572: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Novel microminipig model of atherosclerosis by high fat and high cholesterol diet, established in Japan.

    Miyoshi, Noriaki / Horiuchi, Masahisa / Inokuchi, Yoshinori / Miyamoto, Yoko / Miura, Naoki / Tokunaga, Satatoshi / Fujiki, Makoto / Izumi, Yasukatsu / Miyajima, Hiroaki / Nagata, Ryoichi / Misumi, Kazuhiro / Takeuchi, Toru / Tanimoto, Akihide / Yasuda, Nobuhiro / Yoshida, Hiroki / Kawaguchi, Hiroaki

    In vivo (Athens, Greece)

    2010  Volume 24, Issue 5, Page(s) 671–680

    Abstract: Novel atherosclerotic lesions were induced in the Microminipig (MMP, registered with the Japanese Ministry of Agriculture, Forestry and Fisheries as a novel variety of swine), the smallest pig available for experimental use, by feeding a high fat (12%) ... ...

    Abstract Novel atherosclerotic lesions were induced in the Microminipig (MMP, registered with the Japanese Ministry of Agriculture, Forestry and Fisheries as a novel variety of swine), the smallest pig available for experimental use, by feeding a high fat (12%) and high cholesterol (5%) diet (HFCD) with sodium cholate (SC, 0.7%) (HFCD/SC) for three months. Three MMPs were used: a male fed with normal diet (M-ND), and a male and an ovariectomized female fed with HFCD/SC (M-HFCD/SC and Fx-HFCD/SC). HFCD/SC induced hypercholesterolemia accompanied by an increase in serum total cholesterol (T-Cho), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and cholesterol ester (CE) from the first week. Serum levels of T-Cho, LDL-C and CE reached a maximum in two to three weeks, and HDL-C gradually increased during the experimental period (duration). Serum lipoprotein analysis showed a dominant LDL-C fraction, as seen in humans, in all three MMPs. Body weight gain in the MMPs fed with HFCD/SC was greater than in the animal fed with M-ND. At the end of the experiment, computed tomography scans of conscious animals showed increases in subcutaneous and abdominal fat in those fed with HFCD/SC, suggesting the induction of obesity. Atherosclerotic lesions in systemic arteries (including external and internal iliac arteries, abdominal aorta, coronary artery, cerebral arterial circle), fatty changes, and foamy cell infiltration in the liver and spleen were histopathologically observed in the MMPs fed with HFCD/SC. Atherosclerosis and the pathological findings induced by HFCD/SC in MMPs were similar to the pathological changes associated with human atherosclerosis, suggesting that the MMP has the potential to be a suitable animal model for human atherosclerosis.
    MeSH term(s) Animals ; Arteries/pathology ; Atherosclerosis/pathology ; Atherosclerosis/physiopathology ; Body Weight ; Cholesterol Esters/blood ; Cholesterol, Dietary/blood ; Cholesterol, Dietary/pharmacology ; Cholesterol, HDL/blood ; Cholesterol, LDL/blood ; Disease Models, Animal ; Female ; Humans ; Hypercholesterolemia/pathology ; Hypercholesterolemia/physiopathology ; Intra-Abdominal Fat/diagnostic imaging ; Intra-Abdominal Fat/pathology ; Japan ; Male ; Ovariectomy ; Subcutaneous Fat/diagnostic imaging ; Subcutaneous Fat/pathology ; Swine ; Swine, Miniature ; Tomography, X-Ray Computed
    Chemical Substances Cholesterol Esters ; Cholesterol, Dietary ; Cholesterol, HDL ; Cholesterol, LDL
    Language English
    Publishing date 2010-09
    Publishing country Greece
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 807031-3
    ISSN 1791-7549 ; 0258-851X
    ISSN (online) 1791-7549
    ISSN 0258-851X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2288: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

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