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  1. AU="Ion Romulus Scorei"
  2. AU="Jarmusch, Scott A"
  3. AU="Rupesh Chikhale"
  4. AU=Mubarak Naeem
  5. AU="Lesbordes, Pierre"
  6. AU="Karine Bernardeau"
  7. AU="Post, Zachary D"
  8. AU="Mukherjee, Prattusha"
  9. AU="Yang, Wulin"
  10. AU=Jang Kyoung-Min
  11. AU="Shilpakar, Ramila"
  12. AU="Azad, Sajad"
  13. AU="Connolly, John A"
  14. AU="Šmit, Žiga"
  15. AU=Lee Geun Dong
  16. AU="Laireiter, Anton-Rupert"
  17. AU=Allen Larry A
  18. AU="Jamali, Myriam"
  19. AU="Lima-Filho, Moysés de Oliveira"
  20. AU="Bowen, Ceri"
  21. AU=Demidenko Eugene
  22. AU="Hashemi-Soteh, Mohammad Bagher"
  23. AU="Monfardini, Silvio"
  24. AU="Nasim, Aqeel"
  25. AU=Stennard Fiona A

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  1. Artikel ; Online: The role of boron in the functioning of the osteoarticular system

    Maria-Victoria Racu / Ion Romulus Scorei / Iurie Pinzaru

    The Moldovan Medical Journal, Vol 64, Iss 5, Pp 76-

    2021  Band 80

    Abstract: Background: Boron was classified by the World Health Organization as ‘possible essential elements for human health’. It can be found in different forms in the environment, has beneficial effects on bones and its deprivation can impair calcium and ... ...

    Abstract Background: Boron was classified by the World Health Organization as ‘possible essential elements for human health’. It can be found in different forms in the environment, has beneficial effects on bones and its deprivation can impair calcium and magnesium metabolism and bone development, their health and maintenance. Dietary boron supplementation can help prevent and manage degenerative and inflammatory bones and articular diseases, such as arthritis, osteoarthritis, rheumatoid arthritis and osteoporosis. Relevant articles were identified in PubMed, Google Scholar, ProQuest, and Scopus databases published until June 2021, describing the role of boron in the functioning of the osteoarticular system. Conclusions: From organic and inorganic boron forms that can enter the human body, organic plant based boron compounds are highly bioavailable. In the functioning of the osteoarticular system boron acts by regulation of calcium and magnesium metabolism, enhancing the vitamin D activation process and influencing serum steroid hormone levels. A boron intake equal to or higher than 3 mg per day can help prevent/or correct arthritis, osteoporosis and osteoarthritis. Calcium fructoborate can reduce pain, joint discomfort and increase endogenous vitamin D level in patients with osteoarthritis. Boron may play a role in pathophysiology of rheumatoid arthritis and its severity and a supplementation with boron element may be useful.
    Schlagwörter boron ; boron containing compounds ; osteoarticular system ; osteoarthritis ; rheumatoid arthritis ; Medicine ; R
    Sprache Englisch
    Erscheinungsdatum 2021-11-01T00:00:00Z
    Verlag Scientific Medical Association of Moldova
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: The role of boron in prevention of osteoarticular diseases and its distribution in the Republic of Moldova

    Maria-Victoria RACU / Ion Romulus SCOREI / Iurie PINZARU

    One Health & Risk Management, Vol 2, Iss 4, Pp 54-

    2021  Band 64

    Abstract: Introduction. Boron is a trace mineral that is supposed to be essential for human health. Organic plant based boron compounds are highly bioavailable for humans and can positively influence minerals such as calcium, phosphorus, magnesium and act in ... ...

    Abstract Introduction. Boron is a trace mineral that is supposed to be essential for human health. Organic plant based boron compounds are highly bioavailable for humans and can positively influence minerals such as calcium, phosphorus, magnesium and act in synergy with vitamin D, which are beneficial for osteoarticular health. Material and methods. We made an analysis of 126 bibliographic sources and mapped the Republic of Moldova to the content of boron in deep water and to the adults’ prevalence of rheumatoid arthritis and inflammatory polyarthropathy. Results. Boron is important for osteogenesis and its deficiency can lead to impaired growth and abnormal bones development. It supports bone health in postmenopausal women by reducing urinary loss of the minerals such as calcium, magnesium and phosphorus, which are essential for bone building. In countries where soil was depleted of boron and daily intake of this mineral was 1 mg or lower, the incidence of arthritis was between 20 and 70%. In Moldova, in the regions where boron concentration in deep drinking water were low (0.28 mg/L in well water and 0.51 mg/L in artesian well water) in Soroca in 2019, the prevalence with the rheumatoid arthritis and inflammatory polyarthropathy were high (51.6 per 10000 inhabitants) with one exception, UTA Gagauzia (35.1 per 10000 inhabitants), where we found a high boron concentration in deep drinking water (2.05 mg/L in well water and 2.2 mg/L in artesian well water) in 2015. Conclusions. Boron can affect bone metabolism. In regions where boron concentration in deep drinking water is low, the osteoarticular morbidity can be higher with the exception of UTA Gagauzia, where we suppose that dietary pattern can be a cause of these results. In the future we will study eating habits in this region and a clearer conclusion will be made.
    Schlagwörter osteoarticular diseases ; boron ; boron compounds ; Medicine ; R ; Science ; Q
    Thema/Rubrik (Code) 500
    Sprache Englisch
    Erscheinungsdatum 2021-10-01T00:00:00Z
    Verlag Asociatia de Biosiguranta si Biosecuritate
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: THE INFLUENCE OF BORON-CONTAINING COMPOUNDS ON CARDIOVASCULAR HEALTH

    Maria-Victoria Racu / Ion Romulus Scorei / Iurie Pînzaru

    Arta Medica, Vol 77, Iss

    2020  Band 4

    Abstract: Objectives. Boron is a biological trace element which can be find in different natural compounds, but there is substantial and growing support for it to be classified as an essential nutrient for animals and humans. Previous studies suggest an active ... ...

    Abstract Objectives. Boron is a biological trace element which can be find in different natural compounds, but there is substantial and growing support for it to be classified as an essential nutrient for animals and humans. Previous studies suggest an active involvement of boron-containing compounds in the mediation of several biological reactions in the body, as inflammation and oxidative stress, which can influence occurrence of cardiovascular diseases and can amplify the risk factor impact. Although, the exact role of boron-containing compounds on human body has not yet been established, this work aims to study existing results with a special focus on cardiovascular health. The aim of this study was to review the literature and to detect the possible influence of boron compounds on cardiovascular health. Materials and methods. We made an analysis of more than 150 bibliographic sources that highlighted the boron and its compounds functions, and their impact on cardiovascular risk factors. Results. We found out that the most important compounds for human health are boron esters which can be taken from plant-based food and can be used directly in human cellular metabolism. These compounds have the ability to modulate a response to cardiovascular risk factors, such as oxidative stress and inflammation, but also can influence dyslipidemia, type II diabetes, smoking and obesity. Conclusions. Current studies suggest that a rich boron plant-based diet can have a potential cardioprotective effect and can be involved in reducing of risk factors for cardiovascular diseases.
    Schlagwörter cardiovascular diseases ; boron ; boron compounds ; Medicine ; R ; Surgery ; RD1-811
    Thema/Rubrik (Code) 500
    Sprache Englisch
    Erscheinungsdatum 2020-11-01T00:00:00Z
    Verlag Association of Surgeons of the Republic of Moldova
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Diester Chlorogenoborate Complex

    Andrei Biţă / Ion Romulus Scorei / Nagendra Rangavajla / Ludovic Everard Bejenaru / Gabriela Rău / Cornelia Bejenaru / Maria Viorica Ciocîlteu / Laura Dincă / Johny Neamţu / Andrei Bunaciu / Otilia Constantina Rogoveanu / Mihai Ioan Pop / George Dan Mogoşanu

    Inorganics, Vol 11, Iss 112, p

    A New Naturally Occurring Boron-Containing Compound

    2023  Band 112

    Abstract: The natural compounds of boron have many applications, primarily as a dietary supplement. The research is based on the discovery that the diester chlorogenoborate complex can be detected and quantified from green coffee beans. The study reports that such ...

    Abstract The natural compounds of boron have many applications, primarily as a dietary supplement. The research is based on the discovery that the diester chlorogenoborate complex can be detected and quantified from green coffee beans. The study reports that such a diester molecule can also be synthesized in a stable form via the direct reaction of boric acid and chlorogenic acid in a mixture of acetonitrile–water (1:1, v/v) and left to evaporate over a period of 48 h at room temperature, resulting in a spirocyclic form (diester complex). The diester complex, with its molecular structure and digestibility attributes, has potential application as a prebiotic in gut health and oral health, and as a micronutrient essential for microbiota in humans and animals.
    Schlagwörter diester chlorogenoborate complex ; green coffee bean ; HPTLC/UV ; HPTLC/ESI–MS ; UHPLC/MS ; FTIR ; Inorganic chemistry ; QD146-197
    Sprache Englisch
    Erscheinungsdatum 2023-03-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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