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  1. Article: Ruptured Recurrent Interstitial Ectopic Pregnancy Successfully Managed by Laparoscopy.

    Ungureanu, Claudiu Octavian / Stanculea, Floris Cristian / Iordache, Niculae / Georgescu, Teodor Florin / Ginghina, Octav / Mihailov, Raul / Vacaroiu, Ileana Adela / Georgescu, Dragos Eugen

    Diagnostics (Basel, Switzerland)

    2024  Volume 14, Issue 5

    Abstract: Ectopic pregnancies are a frequently encountered cause of first-trimester metrorrhagia. They occur when an embryo is implanted and grows outside the normal uterine space. Uncommonly, the embryo can be implanted in the intramural portion of the uterine ... ...

    Abstract Ectopic pregnancies are a frequently encountered cause of first-trimester metrorrhagia. They occur when an embryo is implanted and grows outside the normal uterine space. Uncommonly, the embryo can be implanted in the intramural portion of the uterine tube, a condition referred to as interstitial localization. This specific type of ectopic pregnancy may have an unpredictable course, potentially leading to severe uterine rupture and catastrophic bleeding if not promptly diagnosed and managed. We present a rare case of a multiparous 36-year-old female patient who underwent pelvic ultrasonography in the emergency department for intense pelvic pain associated with hypotension and moderate anemia. A history of right salpingectomy for a ruptured tubal ectopic pregnancy 10 years previously was noted. High beta-HCG levels were also detected. A pelvic ultrasound allowed us to suspect a ruptured ectopic interstitial pregnancy at 8 weeks of amenorrhea. An association with hemoperitoneum was suspected, and an emergency laparoscopy was performed. The condition was confirmed intraoperatively, and the patient underwent a right corneal wedge resection with suture of the uterine myometrium. The postoperative course was uneventful, and the patient was discharged on the fourth day postoperatively. Interstitial ectopic pregnancy is a rare yet extremely perilous situation. Timely ultrasound-based diagnosis is crucial as it can enable conservative management with Methotrexate. Delayed diagnosis can lead to uterine rupture with consecutive surgery based on a transection of the pregnancy and cornual uterine resection.
    Language English
    Publishing date 2024-02-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics14050506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Surgical Outcome in Bilateral Inguinal Hernia Repair: Laparoscopic Total Extraperitoneal Approach (TEP) as Best Approach?

    Ungureanu, Claudiu-Octavian / Ginghina, Octav / Stanculea, Floris / Iosifescu, Razvan / Cristian, Dan / Grigorean, Valentin Titus / Popescu, Razvan-Ionut / Dobre, Ramona / Iordache, Niculae

    Maedica

    2024  Volume 18, Issue 4, Page(s) 598–606

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2024-02-08
    Publishing country Romania
    Document type Editorial
    ZDB-ID 2399972-X
    ISSN 2069-6116 ; 1841-9038
    ISSN (online) 2069-6116
    ISSN 1841-9038
    DOI 10.26574/maedica.2023.18.4.598
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Laparoscopic approach of inguinal hernia associated with adult cryptorchidism: case series and literature review.

    Ungureanu, Claudiu / Stanculea, Floris / Ginghina, Octav / Cristian, Daniel A / Grigorean, Valentin T / Popescu, Razvan / Georgescu, Dragos / Iordache, Niculae

    Journal of surgical case reports

    2024  Volume 2024, Issue 4, Page(s) rjae232

    Abstract: Cryptorchidism is defined as the extra-scrotal position of the testes. It is a common disorder in male children, but rarely in adult patients. The association of cryptorchidism with hernia is a common finding in childhood, but is not frequent in adults ... ...

    Abstract Cryptorchidism is defined as the extra-scrotal position of the testes. It is a common disorder in male children, but rarely in adult patients. The association of cryptorchidism with hernia is a common finding in childhood, but is not frequent in adults or the elderly. Herein, we report a series of three cases (28-, 24-, and 34-year-old men) of adult inguinal hernia combined with cryptorchidism successfully managed by laparoscopic surgery under the same operative view. Laparoscopic transabdominal preperitoneal repair and orchiectomy were performed in all patients. No complications occurred in the postoperative period, and the patients were discharged on the first or second postoperative day. Pathological examination of the specimens revealed atrophic testes without malignancy. No hernia recurrence was observed during follow-up. The laparoscopic approach in the combined pathology of inguinal hernia and cryptorchidism is feasible in adult patients and has multiple advantages in terms of diagnosis and management.
    Language English
    Publishing date 2024-04-08
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjae232
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  4. Article: Laparoscopic Mesh Sacropexy for Voluminous Rectocele.

    Vizeteu, R / Iordache, N / Andrei, D

    Chirurgia (Bucharest, Romania : 1990)

    2015  Volume 110, Issue 3, Page(s) 268–274

    Abstract: The rectocele represents a protrusion of the rectum through the rectovaginal fascia, which appears as a bulge in the posterior vaginal wall. Surgical treatment includes many procedures which can be performed by four types of approaches: transvaginal, ... ...

    Abstract The rectocele represents a protrusion of the rectum through the rectovaginal fascia, which appears as a bulge in the posterior vaginal wall. Surgical treatment includes many procedures which can be performed by four types of approaches: transvaginal, transanal, transperineal and transabdominal.Voluminous rectocele cases are rare and often represent a surgical challenge. Only two types of approaches are proved to be feasible for the treatment of a voluminous rectocele, the transvaginal and the transabdominal approaches. To resolve these cases, the authors propose laparoscopic mesh sacropexy.The procedure implies retrorectal dissection and rectovaginal dissection down to the pelvic floor, followed by a rectovaginopexy to the sacral promontory, using an y-shaped polypropylene mesh. One arm of the mesh is fixed to the anterior rectal wall using four stitches and the other arm is sutured to the posterior vaginal wall. The end of the mesh is fixed to the promontory. Thus, the anchoring of the prolapsed rectum and the posterior vaginal fornix to the sacral ligamentis achieved, the damaged rectovaginal fascia being substituted by the polypropylene mesh. The main symptom that was tracked, difficulty in defecation, was significantly improved, none of the patients needed any longer digital maneuvers to empty the rectum. The good results of the first experience make us believe that this procedure is an attractive solution to resolve these difficult cases.
    MeSH term(s) Feasibility Studies ; Female ; Herniorrhaphy/methods ; Humans ; Laparoscopy/instrumentation ; Laparoscopy/methods ; Polypropylenes ; Rectocele/pathology ; Rectocele/surgery ; Surgical Mesh ; Suture Techniques ; Treatment Outcome ; Vagina/surgery
    Chemical Substances Polypropylenes
    Language English
    Publishing date 2015-05
    Publishing country Romania
    Document type Journal Article ; Technical Report
    ZDB-ID 419244-8
    ISSN 1842-368X ; 1221-9118 ; 0009-4730 ; 0377-5003
    ISSN (online) 1842-368X
    ISSN 1221-9118 ; 0009-4730 ; 0377-5003
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  5. Article: Large Symptomatic Inguinoscrotal Seroma Occurred Early after Laparoscopic Total Extraperitoneal Hernia Repair (TEP): a Case Report and Literature Review.

    Ungureanu, Claudiu-Octavian / Stanculea, Floris / Ginghina, Octav / Ene, Cosmin / Stoica, Andrei / Geavlete, Bogdan / Cristian, Daniel Alin / Grigorean, Valentin Titus / Geavlete, Petrisor / Iordache, Niculae

    Maedica

    2024  Volume 19, Issue 1, Page(s) 195–200

    Abstract: Inguinoscrotal hernia (ISH) is an entity for which treatment is under debate. Open surgery is the standard approach, but the laparoscopic technique has a great outcome when used by experienced surgeons. Seroma is one of the complications following ... ...

    Abstract Inguinoscrotal hernia (ISH) is an entity for which treatment is under debate. Open surgery is the standard approach, but the laparoscopic technique has a great outcome when used by experienced surgeons. Seroma is one of the complications following laparoscopic hernia repair for these scrotal hernias, which is due to the large hernia sac, usually transected, leaving in place a remnant of the sac. Conservative measures can be applied for the treatment of seroma; however, in symptomatic cases, puncture and aspiration of fluid are recommended. Sometimes, these seromas can reach a large size and require surgery to remove the remnant sac. Herein, we report the case of a 49-year-old male with a large seroma that occurred four days after the laparoscopic approach - total extraperitoneal repair (TEP) for inguinoscrotal hernia. Conservative measures failed, and because the symptoms were not alleviated, reintervention was opted for. The distal sac was excised and the patient recovered uneventfully. The six-month follow-up did not show any recurrence of the hernia or seroma. We emphasize the importance of sac management in large ISH cases and discuss seromas after laparoscopic hernia repair in such instances.
    Language English
    Publishing date 2024-05-01
    Publishing country Romania
    Document type Editorial
    ZDB-ID 2399972-X
    ISSN 2069-6116 ; 1841-9038
    ISSN (online) 2069-6116
    ISSN 1841-9038
    DOI 10.26574/maedica.2024.19.11.195
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Surgical Approach to Bilateral Inguinal Hernia. A Case-Control Study.

    Ungureanu, Claudiu-Octavian / Ginghina, Octav / Stanculea, Floris / Vacaroiu, Ileana / Ene, Cosmin / Iosifescu, Razvan / Georgescu, Dragoà Eugen / Cristian, Daniel Alin / Grigorean, Valentin Titus / Iordache, Niculae

    Chirurgia (Bucharest, Romania : 1990)

    2024  Volume 118, Issue 6, Page(s) 642–653

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Humans ; Hernia, Inguinal/surgery ; Case-Control Studies ; Retrospective Studies ; Treatment Outcome ; Laparoscopy/methods ; Herniorrhaphy/methods ; Anticoagulants
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2024-01-16
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 419244-8
    ISSN 1842-368X ; 1221-9118 ; 0009-4730 ; 0377-5003
    ISSN (online) 1842-368X
    ISSN 1221-9118 ; 0009-4730 ; 0377-5003
    DOI 10.21614/chirurgia.2023.v.118.i.6.p.642
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Intra operative lesion of the pelvic ureter solved in a minimally invasive manner.

    Stoica, R A / Enache, T / Iordache, N

    Journal of medicine and life

    2014  Volume 7, Issue 3, Page(s) 396–398

    Abstract: Ureteral lesions during open hysterectomy, vaginal hysterectomy or laparoscopic hysterectomy have a rate of 0.2% up to 6%. Multiple complications may occur if the lesion is not recognised intra operatively: hydronephrosis, anuria (bilateral lesion), ... ...

    Abstract Ureteral lesions during open hysterectomy, vaginal hysterectomy or laparoscopic hysterectomy have a rate of 0.2% up to 6%. Multiple complications may occur if the lesion is not recognised intra operatively: hydronephrosis, anuria (bilateral lesion), ureterovaginal fistula, ileus, peritonitis. The rate of recognition of an intra operative ureter lesion is 30% and it could rise up to 90% when cystoscopy with ureteroscopy is used at the end of the intervention. The article presents the case of a 46-year-old patient with uterine fibromatosis, whose pelvic ureter was sectioned during surgery. The lesion was recognised during surgery because, at the end of each intervention, the diuresis was stimulated by injecting Furosemide in order to detect the lesions of the ureters and urinary bladder.
    MeSH term(s) Female ; Furosemide ; Humans ; Hysterectomy/adverse effects ; Intraoperative Complications/diagnosis ; Intraoperative Complications/surgery ; Middle Aged ; Romania ; Ureter/pathology ; Urinary Catheterization/methods
    Chemical Substances Furosemide (7LXU5N7ZO5)
    Language English
    Publishing date 2014-09-15
    Publishing country Romania
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2559353-5
    ISSN 1844-3117 ; 1844-3109 ; 1844-122X
    ISSN (online) 1844-3117 ; 1844-3109
    ISSN 1844-122X
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  8. Article ; Online: ERCP after bariatric surgery--literature review and case report.

    Iorgulescu, A / Turcu, F / Iordache, N

    Journal of medicine and life

    2014  Volume 7, Issue 3, Page(s) 339–342

    Abstract: Obesity is a disease which has become more prevalent in Romania. Bariatric surgical procedures are among the treatment options for obese patients. Obesity and the metabolic disorders induced by it are risk factors for gallstones formation and their ... ...

    Abstract Obesity is a disease which has become more prevalent in Romania. Bariatric surgical procedures are among the treatment options for obese patients. Obesity and the metabolic disorders induced by it are risk factors for gallstones formation and their complications. ERCP is a minimally invasive therapeutic procedure indicated in the treatment of choledochal lithiasis and its complications. ERCP is generally considered the most difficult endoscopic procedure from the technical point of view. The authors have proposed to consider the possibility of performing therapeutic ERCP in patients who have undergone bariatric procedures. Literature data are reviewed and the case of a patient treated in a minimally invasive (laparoendoscopic) way for cholecyst and choledocholithiasis after longitudinal gastrectomy is presented.
    MeSH term(s) Bariatric Surgery/methods ; Bile Ducts/pathology ; Cholangiopancreatography, Endoscopic Retrograde/methods ; Cholangiopancreatography, Endoscopic Retrograde/standards ; Female ; Humans ; Lithiasis/etiology ; Lithiasis/pathology ; Middle Aged ; Obesity/complications ; Obesity/surgery ; Romania ; Ursodeoxycholic Acid/administration & dosage
    Chemical Substances Ursodeoxycholic Acid (724L30Y2QR)
    Language English
    Publishing date 2014-09-15
    Publishing country Romania
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2559353-5
    ISSN 1844-3117 ; 1844-3109 ; 1844-122X
    ISSN (online) 1844-3117 ; 1844-3109
    ISSN 1844-122X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Post-ERCP acute pancreatitis and its risk factors.

    Iorgulescu, A / Sandu, I / Turcu, F / Iordache, N

    Journal of medicine and life

    2013  Volume 6, Issue 1, Page(s) 109–113

    Abstract: Introduction: Endoscopic retrograde cholangiopancreatography (ERCP) is a complex endoscopic technique that evolved from a diagnostic to a mainly therapeutic procedure. This was due to the identification of post-procedural complications that can follow ... ...

    Abstract Introduction: Endoscopic retrograde cholangiopancreatography (ERCP) is a complex endoscopic technique that evolved from a diagnostic to a mainly therapeutic procedure. This was due to the identification of post-procedural complications that can follow both simple ERCP and that associated with the instrumentation of the biliary and pancreatic ductals. The identification of post ERCP complications in a proportion of 5 to 10% of cases, with a mortality rate of 0.33%, imposed their analysis and study of risk factors involved in their occurrence. The significance of post ERCP complications reveals the necessity of their avoidance by adopting additional measures if risk factors are identified.
    Materials and methods: We have retrospectively analyzed 900 cases that underwent ERCP in the Surgery Department of "Sf. Ioan" Clinical Hospital in a period of 17 years. The complications of the procedure were studied. Among them, a special attention was given to post-ERCP acute pancreatitis (pERCP-AP), the most common complication that occurred in the study group. We also tried to find out and highlight the risk factors for this complication.
    Results: ERCP is a relatively safe invasive procedure, yet it has complications (8% of cases), some of them potentially fatal (mortality 0.43%). The most common complications after ERCP are acute pancreatitis (3.7%), papillary bleeding (1.04%), retroperitoneal duodenal perforation (0.69%) and biliary septic complications like acute cholecystitis and cholangitis (1.21%). Acute pancreatitis is by far the most common complication. Risk factors for its occurrence are difficult sphincterotomy with precut use, failure of CBD desobstruction, pancreatic sphincterotomy, repeated injection of contrast in the pancreatic ductal system, dysfunction of the sphincter of Oddi and the absence of changes of chronic pancreatitis. When risk factors are identified, the patients' selection must be very strict and diagnostic ERCP should be avoided in favor of non-invasive diagnostic methods (MRI-cholangiography, echo-endoscopy).
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Cholangiopancreatography, Endoscopic Retrograde/adverse effects ; Cholangiopancreatography, Endoscopic Retrograde/mortality ; Female ; Humans ; Male ; Middle Aged ; Pancreatitis, Acute Necrotizing/etiology ; Risk Factors ; Young Adult
    Language English
    Publishing date 2013-03-25
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 2559353-5
    ISSN 1844-3117 ; 1844-3109 ; 1844-122X
    ISSN (online) 1844-3117 ; 1844-3109
    ISSN 1844-122X
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  10. Article ; Online: Cecal Malakoplakia - an Unusual Cause of Anemia in Liver Cirrhosis.

    Dina, Ion / Iacobescu, Claudia / Iordache, Nicolae / Gheorghița, Sergiu / Gurghean, Adriana

    Journal of gastrointestinal and liver diseases : JGLD

    2019  Volume 28, Issue 3, Page(s) 263

    Abstract: ...

    Abstract .
    MeSH term(s) Anemia, Iron-Deficiency/diagnosis ; Anemia, Iron-Deficiency/etiology ; Anemia, Macrocytic/diagnosis ; Anemia, Macrocytic/etiology ; Cecal Diseases/complications ; Cecal Diseases/diagnostic imaging ; Cecal Diseases/surgery ; Esophageal and Gastric Varices/diagnosis ; Esophageal and Gastric Varices/etiology ; Gastrointestinal Hemorrhage/diagnosis ; Gastrointestinal Hemorrhage/etiology ; Humans ; Liver Cirrhosis, Alcoholic/complications ; Liver Cirrhosis, Alcoholic/diagnosis ; Malacoplakia/complications ; Malacoplakia/diagnosis ; Malacoplakia/surgery ; Male ; Middle Aged ; Treatment Outcome
    Language English
    Publishing date 2019-09-01
    Publishing country Romania
    Document type Case Reports
    ZDB-ID 2427021-0
    ISSN 1842-1121 ; 1841-8724
    ISSN (online) 1842-1121
    ISSN 1841-8724
    DOI 10.15403/jgld-418
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