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Article: Possibilità chirurgiche nelle metastasi ossee da carcinomi renali.

Ippolito, Vincenzo

2011 Volume 78 Suppl 18, Page(s) 1–4

Abstract: Kidney cancer, together with breast and lung, is one of the most frequent primaries causing bone mestastases which require some kind of surgical treatment. Renal mets, however, have distinguished features making their surgical treatment a real challenge: ...

Title translation	Surgical chances in kidney cancer bone metastases.
Abstract	Kidney cancer, together with breast and lung, is one of the most frequent primaries causing bone mestastases which require some kind of surgical treatment. Renal mets, however, have distinguished features making their surgical treatment a real challenge: their open treatment is at high risk for massive bleeding and the severe destruction of bone-stock makes reconstruction often very difficult. Nevertheless, the surgical treatment of these metastases can dramatically improve the patient's quality of life. For the important problems which must be faced and solved, surgery of Renal Cell metastases should not be left to general orthopedic surgeons but these patients should be referred to Centers with a major experience in MusculoSkeletal Oncology.
MeSH term(s)	Bone Neoplasms/secondary ; Bone Neoplasms/surgery ; Carcinoma, Renal Cell/secondary ; Carcinoma, Renal Cell/surgery ; Humans ; Kidney Neoplasms/pathology ; Kidney Neoplasms/surgery ; Quality of Life ; Retrospective Studies ; Treatment Outcome
Language	Italian
Publishing date	2011-10
Publishing country	Italy
Document type	English Abstract ; Journal Article
ZDB-ID	204043-8
ISSN	1724-6075 ; 0391-5603 ; 0376-0057
ISSN (online)	1724-6075
ISSN	0391-5603 ; 0376-0057
DOI	10.5301/RU.2011.8744
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Article ; Online: A long-term experience with Mutars tumor megaprostheses: analysis of 187 cases.

Pala, Elisa / Trovarelli, Giulia / Ippolito, Vincenzo / Berizzi, Antonio / Ruggieri, Pietro

European journal of trauma and emergency surgery : official publication of the European Trauma Society

2021 Volume 48, Issue 3, Page(s) 2483–2491

Abstract: Purpose: Modular megaprostheses have widely replaced allografts, as a reconstructive option; however, failures of these devices remain high. Aim of this study was to analyze outcomes, survival of the implants, incidence and types of complications with ... ...

Abstract	Purpose: Modular megaprostheses have widely replaced allografts, as a reconstructive option; however, failures of these devices remain high. Aim of this study was to analyze outcomes, survival of the implants, incidence and types of complications with Mutars modular endoprostheses at long term. Methods: Between 2000 and 2019, 187 Mutars prostheses were implanted in two dedicated centers: 72 upper limbs and 115 lower limbs reconstructions. Diagnoses included 107 primary malignant bone or soft tissue tumors, 65 metastases, 8 benign bone tumors and 7 non-oncologic cases. Silver-coated prostheses were used in 118/187 (63%) cases. Results: At last follow-up, 76.5% of patients had retained their implant. The overall failure rate was 23.5% at a mean of 1.7 years. There were 22 mechanical failures and 22 non-mechanical failures. The overall implant survival to all types of failure was 68% and 52% at 5 and 10 years, respectively. Infection was the most common mode of failure with an incidence of 6.9%. Implant survival to infection was better for silver-coated implants than for standard implants even if with no significant difference (p = 0.56). Functional results were satisfactory in 97% of patients. Conclusions: The overall implant survival at long term was satisfactory with Mutars prostheses. The incidence of complications with Mutars prosthesis is in line with the incidence reported in the literature with other types of tumor prosthesis. The most frequent cause of failure was infection with a lower incidence in silver-coated prostheses; silver coating seems to prevent infection in distal femur and proximal tibia. The silver coating seems to be particularly useful in two-stage revisions with a lower incidence of secondary amputation. In higher risk patients, silver-coated prostheses are the preferable choice for the reduction of the reinfection rate. The functional results of Mutars prostheses were excellent or good in most of cases. The current paper is design to enhance the literature on megaprosthesis in tumor surgery, proven that this system is one of the most used all over the word and one of the best performing.
MeSH term(s)	Bone Neoplasms/pathology ; Bone Neoplasms/surgery ; Femur/pathology ; Humans ; Prostheses and Implants ; Prosthesis Failure ; Reoperation ; Retrospective Studies ; Silver ; Tibia/pathology ; Treatment Outcome
Chemical Substances	Silver (3M4G523W1G)
Language	English
Publishing date	2021-11-02
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2275480-5
ISSN	1863-9941 ; 1863-9933
ISSN (online)	1863-9941
ISSN	1863-9933
DOI	10.1007/s00068-021-01809-7
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Article: Comparative Analysis of Intellectual Quotient in Developmental Population with Severe Hearing Loss: Hearing Aids vs. Cochlear Implant Users.

Di Stadio, Arianna / De Luca, Pietro / Ippolito, Valentina / Vedova, Paola / Garofalo, Sabina / Turchetta, Rosaria / Ferlito, Salvatore / Della Volpe, Antonio

Life (Basel, Switzerland)

2023 Volume 14, Issue 1

Abstract: The development of language, memory and intellectual functions is linked to normal hearing and correct sounds interpretation. Hearing loss (HL), especially in its severe form, negatively affects the development of these functions. This prospective study ... ...

Abstract	The development of language, memory and intellectual functions is linked to normal hearing and correct sounds interpretation. Hearing loss (HL), especially in its severe form, negatively affects the development of these functions. This prospective study aimed at comparing the Intelligent Quotients (IQ) of children with cochlear implants (CI) with the ones of people wearing hearing aids (HA) after one year of hearing rehabilitation. 21 subjects with severe/profound bilateral hearing loss (deafness) were included in this study. Eleven children with congenital profound HL underwent CI and ten children with moderate to severe HL (congenital and acquired) were rehabilitated by HA. Children's IQs were assessed at enrolment (T0) and 12 months after hearing aids/CI use plus speech therapy. Statistical analyses were performed to analyze the data within and between groups. Comparison of IQs showed no statistically significant differences between CI and HA none at T0 and T1. The subtests showed lower scores in verbal comprehension and process speed index in patients treated with HA when compared to CI. This study showed that auditory rehabilitation can support the normal development of cognitive function in children between six and eight years of age. The use of the correct hearing aids based on the patient's hearing thresholds is important to maximize the rehabilitation outcomes. Due to the small sample size, although stratified for age, our results must be considered preliminary and further analyses on larger samples are needed to confirm our data.
Language	English
Publishing date	2023-12-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662250-6
ISSN	2075-1729
ISSN	2075-1729
DOI	10.3390/life14010012
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Article ; Online: Use of a 3D reconstruction model in a patient with severe atresia auris for optimal placement of Bonebridge transcutaneous bone conduction implant.

Della Volpe, Antonio / De Lucia, Antonietta / Ippolito, Valentina / Pastore, Vincenzo / Iuppariello, Luigi / Formisano, Mario / Clemente, Fabrizio / Di Stadio, Arianna

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

2021 Volume 278, Issue 9, Page(s) 3559–3564

Abstract: Purpose: Patients affected by severe atresia auris (AA) can be a challenge during hearing restoration surgery due to the abnormal position of vascular and nervous structures in the bone. A 3D reconstruction model of malformed temporal bones can be ... ...

Abstract	Purpose: Patients affected by severe atresia auris (AA) can be a challenge during hearing restoration surgery due to the abnormal position of vascular and nervous structures in the bone. A 3D reconstruction model of malformed temporal bones can be helpful for planning surgery and optimizing intra-, peri-, and post-operative results. Method: A 5-year-old girl with severe AA on the right side was implanted with a Bonebridge transcutaneous bone conduction implant (tBCI). 3D printing was used to reproduce the malformed temporal bone, find a good position for the tBCI and plan out the surgical details in advance. Hearing tests were performed before and after surgery and information about intra-, peri-, and post-operative outcomes were collected. Results: The patient did not show any negative outcomes and, thanks to the Bonebridge, completely recovered hearing on the right side. Conclusions: 3D printing is a useful tool for planning surgery in AA patients and for preventing possible risks related to the unknown malformed anatomy.
MeSH term(s)	Bone Conduction ; Child, Preschool ; Ear ; Female ; Hearing Aids ; Hearing Loss, Conductive/diagnosis ; Hearing Loss, Conductive/etiology ; Hearing Loss, Conductive/surgery ; Humans ; Imaging, Three-Dimensional ; Prostheses and Implants
Language	English
Publishing date	2021-01-03
Publishing country	Germany
Document type	Case Reports ; Journal Article
ZDB-ID	1017359-6
ISSN	1434-4726 ; 0937-4477
ISSN (online)	1434-4726
ISSN	0937-4477
DOI	10.1007/s00405-020-06528-0
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Article ; Online: Reexploring the cation ordering and magnetic cation substitution effects on the elastic anisotropy of aluminum spinels

Núñez Valdez, M. / Bruschini, E. / Speziale, S. / Bosi, F. / Fregola, R. / D’Ippolito, V. / Andreozzi, G.

Journal of Applied Physics

2018

Publishing country	de
Document type	Article ; Online
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Article ; Online: A Novel Bone Conduction Hearing System May Improve Memory Function in Children with Single Side Hearing loss: A Case-Control Study.

Di Stadio, Arianna / Dipietro, Laura / De Lucia, Antonietta / Ippolito, Valentina / Ishai, Reuven / Garofalo, Sabina / Pastore, Vincenzo / Ricci, Giampietro / Della Volpe, Antonio

The journal of international advanced otology

2020 Volume 16, Issue 2, Page(s) 158–164

Abstract: Objectives: To evaluate the effects of an adhesive adapter prosthesis (AAP) on memory function in pediatric subjects with single side hearing loss (SSHL).: Materials and methods: Case-control study. 19 pediatric subjects with mild to moderate SSHL ... ...

Abstract	Objectives: To evaluate the effects of an adhesive adapter prosthesis (AAP) on memory function in pediatric subjects with single side hearing loss (SSHL). Materials and methods: Case-control study. 19 pediatric subjects with mild to moderate SSHL treated with AAP and 15 subjects with normal hearing (control group) were included in this study. Working and short-term memory functions were tested in all subjects, in silence and noise conditions. In SSHL subjects, tests were performed before the AAP was applied (T0) and at 1-month (T1) follow-up. The control group was tested once. Results: AAP significantly improved working memory function in noise as measured at T1 (p<0.01) compared with T0, but T1 scores in children with SSHL remained significantly different from the ones of the control group (p<0.01). AAP also significantly improved short- term memory function test scores at T1 compared with T0 (p<0.01), but despite being in the normal range for the subjects' age, the scores remained significantly different from those of the control group (p<0.01). Conclusion: In pediatric subjects with mild, moderate, and moderate-severe SSHL, restoration of bilateral hearing through AAP improved short-term memory function and working memory function in noise, as measured at 1 month follow-up; however, AAP did not seem to lead to a full restoration of such functions as measured by a comparison with healthy controls. Further studies with longer follow-ups might help elucidate whether AAP can elicit further improvements in memory functions.
MeSH term(s)	Bone Conduction ; Case-Control Studies ; Child ; Child, Preschool ; Correction of Hearing Impairment/instrumentation ; Correction of Hearing Impairment/psychology ; Female ; Hearing ; Hearing Aids ; Hearing Loss, Sensorineural/physiopathology ; Hearing Loss, Sensorineural/rehabilitation ; Hearing Loss, Unilateral/physiopathology ; Hearing Loss, Unilateral/rehabilitation ; Humans ; Male ; Memory, Short-Term/physiology ; Noise ; Treatment Outcome
Language	English
Publishing date	2020-07-30
Publishing country	Turkey
Document type	Journal Article
ISSN	2148-3817
ISSN (online)	2148-3817
DOI	10.5152/iao.2020.7941
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Article: Does Unilateral Hearing Loss Impair Working Memory? An Italian Clinical Study Comparing Patients With and Without Hearing Aids.

Della Volpe, Antonio / Ippolito, Valentina / Roccamatisi, Dalila / Garofalo, Sabina / De Lucia, Antonietta / Gambacorta, Valeria / Longari, Fabrizio / Ricci, Giampietro / Di Stadio, Arianna

Frontiers in neuroscience

2020 Volume 14, Page(s) 905

Abstract: Working memory (WM) function can be reduced in patients suffering from unilateral hearing loss (UHL) and can affect their academic performance. We aimed to compare the WM abilities of three categories of children with UHL: patients implanted with hearing ...

Abstract	Working memory (WM) function can be reduced in patients suffering from unilateral hearing loss (UHL) and can affect their academic performance. We aimed to compare the WM abilities of three categories of children with UHL: patients implanted with hearing aids (HAs), patients receiving a bone-anchored hearing implant (BAHI), and subjects who did not receive hearing devices. A randomized clinical study, in which 45 children (mean age: 9.5 years) were evaluated by pure tone audiometry (to identify the side and the severity of the UHL), was conducted in a tertiary referral center. Patients were simply randomized into three groups: (1) children without HAs (No-HA group), (2) patients with a (digital) HA (HA group), and (3) children with a BAHI (BAHI group). Their working and short-term memories were studied in both noisy and silent conditions at the recruiting time (T0, baseline) and 6 months after (T1) the treatment. Statistical analyses were performed to analyze the variances between T0 and T1 within each group and between the three groups. The No-HA group improved its T1 WM scores in silence (
Language	English
Publishing date	2020-09-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2411902-7
ISSN	1662-453X ; 1662-4548
ISSN (online)	1662-453X
ISSN	1662-4548
DOI	10.3389/fnins.2020.00905
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Conference proceedings ; Online: Structural relaxation around Co2+ in synthetic blue (Mg,Co)Al2O4spinelcrystals

Andreozzi, G. / D’Ippolito, V. / Bosi, F. / Halenius, U.

Abstracts

2011

Language	English
Publishing country	de
Document type	Conference proceedings ; Online
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Article ; Online: Baseline characteristics of postmenopausal women with osteoporosis treated with teriparatide in a real-world setting in Latin America: a subregional analysis from the Asia and Latin America Fracture Observational Study (ALAFOS).

Cunha-Borges, Joao L / Mier, Guillermo Meléndez / Casas, Noemí / Medina, Adriana / Molina, Jose Fernando / García, Maria Laura / Oliveria, Lindomar Guimarães / Caselato, Marcela S / Cruz, Angélica C / Ippolito, Vanessa / Flórez, Sandra

Advances in rheumatology (London, England)

2019 Volume 59, Issue 1, Page(s) 46

Abstract: Background: Osteoporosis is a major healthcare concern in Latin America. Factors such as changing demographics, fragmented healthcare systems, and financial considerations may result in a huge increase in the burden of osteoporosis in this region. The ... ...

Abstract	Background: Osteoporosis is a major healthcare concern in Latin America. Factors such as changing demographics, fragmented healthcare systems, and financial considerations may result in a huge increase in the burden of osteoporosis in this region. The aim of this article is to describe the baseline clinical characteristics and fracture history of patients who are prescribed teriparatide in normal clinical practice in Latin America. Methods: We conducted a prospective, multinational, observational study (the Asia and Latin America Fracture Observational Study [ALAFOS]) in 20 countries worldwide to assess the incidence of fractures in postmenopausal women with osteoporosis receiving teriparatide as a part of routine clinical practice in a real-world setting. In this subregional analysis of the ALAFOS study, we report the clinical characteristics, fracture history, risk factors for osteoporosis, comorbidities, previous osteoporosis therapies and health-related quality of life measures at baseline for patients from the four participant Latin American countries: Argentina, Brazil, Colombia, and Mexico. Results: The Latin America subregional cohort included 546 postmenopausal women (mean [SD] age: 71.0 [10.1] years; range: 40-94 years), constituting 18% of the ALAFOS total population. The baseline mean (SD) bone mineral density T-scores were - 3.02 (1.23) at the lumbar spine and - 2.31 (0.96) at the femoral neck; 62.8% of patients had a history of low trauma fracture after the age of 40 years and 39.7% of patients had experienced ≥1 fall in the past year. Osteoporosis medications were used by 70.9% of patients before initiating teriparatide. The median (Q1, Q3) EQ-5D-5 L Visual Analog Scale (VAS) scores for perceived health status at baseline was 70 (50, 80). The mean (SD) worst back pain numeric rating scale score for the overall Latin American cohort was 4.3 (3.4) at baseline. Conclusions: This baseline analysis of the Latin America subregion of the ALAFOS study indicates that patients who are prescribed teriparatide in the four participant countries had severe osteoporosis and high prevalence of fractures. They also had back pain and poor health-related quality of life. The proportions of patients with severe or extreme problems on the EQ-5D-5 L individual domains were lower than those in the overall ALAFOS study population.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Argentina/epidemiology ; Back Pain/drug therapy ; Bone Density ; Bone Density Conservation Agents/therapeutic use ; Brazil/epidemiology ; Colombia/epidemiology ; Comorbidity ; Female ; Glucocorticoids/therapeutic use ; Humans ; Latin America ; Mexico/epidemiology ; Middle Aged ; Osteoporosis/drug therapy ; Osteoporosis/epidemiology ; Osteoporosis/etiology ; Osteoporotic Fractures/epidemiology ; Osteoporotic Fractures/etiology ; Pain Measurement ; Postmenopause ; Prevalence ; Prospective Studies ; Quality of Life ; Reproductive History ; Risk Factors ; Spinal Fractures/epidemiology ; Spinal Fractures/etiology ; Teriparatide/therapeutic use ; Visual Analog Scale
Chemical Substances	Bone Density Conservation Agents ; Glucocorticoids ; Teriparatide (10T9CSU89I)
Language	English
Publishing date	2019-11-08
Publishing country	England
Document type	Journal Article ; Multicenter Study ; Observational Study ; Research Support, Non-U.S. Gov't
ISSN	2523-3106
ISSN (online)	2523-3106
DOI	10.1186/s42358-019-0088-2
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Article: Osteolisi vertebrale. Ma di quale natura?

Bergonzini, R / Ippolito, V / Favagrossa, G M

La Radiologia medica

1998 Volume 96, Issue 6, Page(s) 654–656

Title translation	Vertebral osteolysis: but what kind?.
MeSH term(s)	Adult ; Female ; Humans ; Lumbar Vertebrae ; Osteolysis/classification ; Osteolysis/diagnostic imaging ; Radiography ; Spinal Diseases/classification ; Spinal Diseases/diagnostic imaging
Language	Italian
Publishing date	1998-12
Publishing country	Italy
Document type	Case Reports ; Journal Article
ZDB-ID	205751-7
ISSN	1826-6983 ; 0033-8362
ISSN (online)	1826-6983
ISSN	0033-8362
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