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  1. Article: Hæmorrhagic Malarial Fever.

    Jones, Isaac J

    Texas medical journal (Austin, Tex.)

    2023  Volume 11, Issue 3, Page(s) 105–111

    Language English
    Publishing date 2023-03-23
    Publishing country United States
    Document type Journal Article
    ISSN 0892-8495
    ISSN 0892-8495
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Esthetic surgery of the face

    Peled, Isaac J.

    2004  

    Author's details ed. by Isaac J. Peled
    Keywords Face / surgery ; Reconstructive Surgical Procedures / methods
    Language English
    Size VI, 280 S. : zahlr. Ill., graph. Darst.
    Publisher Taylor & Francis
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT013788612
    ISBN 1-84184-247-8 ; 978-1-84184-247-9
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2004 A 2045 order for loan Magazin

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  3. Article ; Online: Faster Convergence in Deep-Predictive-Coding Networks to Learn Deeper Representations.

    Sledge, Isaac J / Principe, Jose C

    IEEE transactions on neural networks and learning systems

    2023  Volume 34, Issue 8, Page(s) 5156–5170

    Abstract: Deep-predictive-coding networks (DPCNs) are hierarchical, generative models. They rely on feed-forward and feedback connections to modulate latent feature representations of stimuli in a dynamic and context-sensitive manner. A crucial element of DPCNs is ...

    Abstract Deep-predictive-coding networks (DPCNs) are hierarchical, generative models. They rely on feed-forward and feedback connections to modulate latent feature representations of stimuli in a dynamic and context-sensitive manner. A crucial element of DPCNs is a forward-backward inference procedure to uncover sparse, invariant features. However, this inference is a major computational bottleneck. It severely limits the network depth due to learning stagnation. Here, we prove why this bottleneck occurs. We then propose a new forward-inference strategy based on accelerated proximal gradients. This strategy has faster theoretical convergence guarantees than the one used for DPCNs. It overcomes learning stagnation. We also demonstrate that it permits constructing deep and wide predictive-coding networks. Such convolutional networks implement receptive fields that capture well the entire classes of objects on which the networks are trained. This improves the feature representations compared with our lab's previous nonconvolutional and convolutional DPCNs. It yields unsupervised object recognition that surpass convolutional autoencoders and is on par with convolutional networks trained in a supervised manner.
    Language English
    Publishing date 2023-08-04
    Publishing country United States
    Document type Journal Article
    ISSN 2162-2388
    ISSN (online) 2162-2388
    DOI 10.1109/TNNLS.2021.3115698
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Advances and challenges in slippery covalently-attached liquid surfaces.

    Gresham, Isaac J / Neto, Chiara

    Advances in colloid and interface science

    2023  Volume 315, Page(s) 102906

    Abstract: Over the past decade, a new class of slippery, anti-adhesive surfaces known as slippery covalently-attached liquid surfaces (SCALS) has emerged, characterized by low values of contact angle hysteresis (CAH, less than 5°) with water and most solvents. ... ...

    Abstract Over the past decade, a new class of slippery, anti-adhesive surfaces known as slippery covalently-attached liquid surfaces (SCALS) has emerged, characterized by low values of contact angle hysteresis (CAH, less than 5°) with water and most solvents. Despite their nanoscale thickness (1 to 5 nm), SCALS exhibit behavior similar to lubricant-infused surfaces, including high droplet mobility and the ability to prevent icing, scaling, and fouling. To date, SCALS have primarily been obtained using grafted polydimethylsiloxane (PDMS), though there are also examples of polyethylene oxide (PEO), perfluorinated polyether (PFPE), and short-chain alkane SCALS. Importantly, the precise physico-chemical characteristics that enable ultra-low CAH are unknown, making rational design of these systems impossible. In this review, we conduct a quantitative and comparative analysis of reported values of CAH, molecular weight, grafting density, and layer thickness for a range of SCALS. We find that CAH does not scale monotonically with any reported parameter; instead, the CAH minimum is found at intermediate values. For PDMS, optimal behavior is observed at advancing contact angle of 106°, molecular weight between 2 and 10 kg mol
    Language English
    Publishing date 2023-04-18
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 210507-x
    ISSN 1873-3727 ; 0001-8686
    ISSN (online) 1873-3727
    ISSN 0001-8686
    DOI 10.1016/j.cis.2023.102906
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Functional analysis of problem behavior: A 40-year review.

    Melanson, Isaac J / Fahmie, Tara A

    Journal of applied behavior analysis

    2023  Volume 56, Issue 2, Page(s) 262–281

    Abstract: Extensive reviews of functional analysis literature were conducted 10 (Beavers et al., 2013) and 20 (Hanley et al., 2003) years ago; we expanded this review to capture the vast and innovative functional analysis research that has occurred over the past ... ...

    Abstract Extensive reviews of functional analysis literature were conducted 10 (Beavers et al., 2013) and 20 (Hanley et al., 2003) years ago; we expanded this review to capture the vast and innovative functional analysis research that has occurred over the past decade. Our review produced 1,333 functional analysis outcomes from 326 studies on the functional analysis of problem behavior between June 2012 and May 2022. Some characteristics of functional analysis studies were similar across the current and previous two reviews (e.g., child participants, developmental disability diagnosis, use of line graphs depicting session means, differentiated response outcomes). Other characteristics deviated from the previous two reviews (e.g., increase in autistic representation, outpatient settings, use of supplementary assessments, the inclusion of tangible conditions, and multiple function outcomes; decrease in session durations). We update previously reported participant and methodological characteristics, summarize outcomes, comment on recent trends, and propose future directions in the functional analysis literature.
    MeSH term(s) Child ; Humans ; Problem Behavior ; Autistic Disorder
    Language English
    Publishing date 2023-03-09
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 218065-0
    ISSN 1938-3703 ; 0021-8855
    ISSN (online) 1938-3703
    ISSN 0021-8855
    DOI 10.1002/jaba.983
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Gutsy memory T cells stand their ground against pathogens.

    Jensen, Isaac J / Farber, Donna L

    Science immunology

    2022  Volume 7, Issue 77, Page(s) eade7168

    Abstract: Elegant fate-mapping models to label intestinal tissue-resident memory ... ...

    Abstract Elegant fate-mapping models to label intestinal tissue-resident memory CD8
    MeSH term(s) Immunologic Memory ; CD8-Positive T-Lymphocytes ; Memory T Cells
    Language English
    Publishing date 2022-11-04
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2470-9468
    ISSN (online) 2470-9468
    DOI 10.1126/sciimmunol.ade7168
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  7. Article ; Online: An Optimized Synthesis of Fmoc-l-Homopropargylglycine-OH.

    Polyak, Daniel / Krauss, Isaac J

    The Journal of organic chemistry

    2022  Volume 87, Issue 5, Page(s) 3841–3844

    Abstract: An efficient multigram synthesis of alkynyl amino acid Fmoc-l-homopropargylglycine-OH is described. A double Boc protection is optimized for high material throughput, and the key Seyferth-Gilbert homologation is optimized to avoid racemization. Eighteen ... ...

    Abstract An efficient multigram synthesis of alkynyl amino acid Fmoc-l-homopropargylglycine-OH is described. A double Boc protection is optimized for high material throughput, and the key Seyferth-Gilbert homologation is optimized to avoid racemization. Eighteen grams of the enantiopure (>98% ee) noncanonical amino acid was readily generated for use in solid phase synthesis to make peptides that can be functionalized by copper-assisted alkyne-azide cycloaddition.
    MeSH term(s) Alkynes/chemistry ; Amino Acids/chemistry ; Azides/chemistry ; Fluorenes/chemistry ; Glycine/analogs & derivatives ; Solid-Phase Synthesis Techniques
    Chemical Substances Alkynes ; Amino Acids ; Azides ; Fluorenes ; homopropargylglycine ; Glycine (TE7660XO1C)
    Language English
    Publishing date 2022-02-08
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.1c03027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4473: Show issues Location:
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  8. Article: An Optimized Synthesis of Fmoc-l-Homopropargylglycine-OH

    Polyak, Daniel / Krauss, Isaac J.

    Journal of organic chemistry. 2022 Feb. 08, v. 87, no. 5

    2022  

    Abstract: An efficient multigram synthesis of alkynyl amino acid Fmoc-l-homopropargylglycine-OH is described. A double Boc protection is optimized for high material throughput, and the key Seyferth–Gilbert homologation is optimized to avoid racemization. Eighteen ... ...

    Abstract An efficient multigram synthesis of alkynyl amino acid Fmoc-l-homopropargylglycine-OH is described. A double Boc protection is optimized for high material throughput, and the key Seyferth–Gilbert homologation is optimized to avoid racemization. Eighteen grams of the enantiopure (>98% ee) noncanonical amino acid was readily generated for use in solid phase synthesis to make peptides that can be functionalized by copper-assisted alkyne–azide cycloaddition.
    Keywords amino acids ; cycloaddition reactions ; enantiomers ; organic chemistry ; peptides
    Language English
    Dates of publication 2022-0208
    Size p. 3841-3844.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.1c03027
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

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  9. Article: Operative Dentistry.

    Wetherbee, Isaac J

    The American journal of dental science

    2019  Volume 14, Issue 3, Page(s) 125–131

    Language English
    Publishing date 2019-02-12
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Les cellules mésenchymateuses orales, une niche spécifique, du développement à la régénération.

    Isaac, Juliane / Clerc, Mélodie M / Ferré, François C / Fournier, Benjamin P J

    Medecine sciences : M/S

    2024  Volume 40, Issue 1, Page(s) 24–29

    Abstract: Oral buccal tissues, including bone and mucosa, have unique properties. Oral mucosal fibroblasts and jaw osteoblasts, both derived from Cranial Neural Crest cells, play a key role in healing and repair. These cells express a specific repertoire of genes ... ...

    Title translation Oral mesenchymal cells, a specific niche, from development to regeneration.
    Abstract Oral buccal tissues, including bone and mucosa, have unique properties. Oral mucosal fibroblasts and jaw osteoblasts, both derived from Cranial Neural Crest cells, play a key role in healing and repair. These cells express a specific repertoire of genes with their regenerative properties, but also craniofacial diseases. Understanding these tissues holds clinical promise for tissue regeneration and repair of bone and mucosal defects. These multidisciplinary advances also offer potential for better management of periodontal-related conditions and improved oral health.
    MeSH term(s) Humans ; Mouth Mucosa ; Wound Healing ; Mesenchymal Stem Cells
    Language French
    Publishing date 2024-02-01
    Publishing country France
    Document type English Abstract ; Journal Article
    ZDB-ID 632733-3
    ISSN 1958-5381 ; 0767-0974
    ISSN (online) 1958-5381
    ISSN 0767-0974
    DOI 10.1051/medsci/2023191
    Database MEDical Literature Analysis and Retrieval System OnLINE

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