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Book ; Online: Non-Communicable Disease Prevention : Best Buys, Wasted Buys and Contestable Buys

Isaranuwatchai, Wanrudee / Archer, Rachel A. / Teerawattananon, Yot / Culyer, Anthony

2019

Keywords	Medicine: general issues ; Public health & preventive medicine ; Personal & public health ; Non-communicable diseases ; NCDs ; death ; practical guidelines ; Prince Mahidol Award Conference ; PMAC
Size	1 electronic resource (220 pages)
Publisher	Open Book Publishers
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021030728
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: [No title information]

Watt, Jennifer A / Isaranuwatchai, Wanrudee / Grossman, Linda / Straus, Sharon E

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

2024 Volume 196, Issue 3, Page(s) E110–E112

Title translation	Médicaments modificateurs de la maladie d’Alzheimer: implications pour la population canadienne.
MeSH term(s)	Humans ; Alzheimer Disease/drug therapy ; Canada ; Antibodies, Monoclonal, Humanized/therapeutic use
Chemical Substances	lecanemab (12PYH0FTU9) ; Antibodies, Monoclonal, Humanized
Language	French
Publishing date	2024-01-28
Publishing country	Canada
Document type	Journal Article
ZDB-ID	215506-0
ISSN	1488-2329 ; 0008-4409 ; 0820-3946
ISSN (online)	1488-2329
ISSN	0008-4409 ; 0820-3946
DOI	10.1503/cmaj.230595-f
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Article ; Online: The association between health costs and physical inactivity; analysis from the Physical Activity at Work study in Thailand.

Akksilp, Katika / Isaranuwatchai, Wanrudee / Teerawattananon, Yot / Chen, Cynthia

Frontiers in public health

2023 Volume 11, Page(s) 1037699

Abstract: Introduction: Physical inactivity increases the risks of several common yet serious non-communicable diseases, costing a tremendous amount of health expenditure globally. This study aimed to estimate the association between health costs and physical ... ...

Abstract	Introduction: Physical inactivity increases the risks of several common yet serious non-communicable diseases, costing a tremendous amount of health expenditure globally. This study aimed to estimate the association between health costs and physical inactivity in Thailand. Methods: Data from the Physical Activity at Work cluster randomized controlled trial participants with valid objective physical activity data were extracted. Health costs were collected using the Health and Welfare Survey and the Work Productivity and Activity Impairment Questionnaire and were categorized into past-month outpatient illness, past-year inpatient illness, and past-week presenteeism and absenteeism. Time spent in moderate-to-vigorous physical activity was used to determine the activity level according to the current guideline (i.e., ≥150 minutes moderate-intensity or ≥75 minutes vigorous-intensity equivalent physical activity per week). The primary analysis evaluated the association between direct cost (treatment and travel costs) and societal cost (direct cost plus absenteeism due to the illness) of past-month outpatient illness and physical inactivity using a two-part model. Results: In total, 277 participants with a mean age of 38.7 were included. Average direct and societal cost due to past-month outpatient illness were 146 THB (3.99 USD) (SD = 647 THB) and 457 THB (12.5 USD) (SD = 1390 THB), respectively. Compared to active participants, direct and societal cost of past-month outpatient illness were 153 THB (4.18 USD) (95%CI: -54.7 to 360 THB) and 426 THB (11.7 USD) (95%CI: 23.3 to 829 THB) higher in physically inactive individuals, respectively, adjusted for covariates. The additional societal cost of past-month outpatient illness was 145% higher in physically inactive participants compared to active participants. On the other hand, there was no significant association in direct and societal cost of past-year inpatient illness nor past-week indirect costs between physically active and non-active participants. Discussion: Results were similar to recent findings in different countries. However, the findings should be generalized with caution due to the small sample size and potential bias from reverse causation. Future research is crucial for clarifying the health costs of physical inactivity in Thailand and other countries.
MeSH term(s)	Humans ; Adult ; Thailand ; Sedentary Behavior ; Health Care Costs ; Health Expenditures ; Surveys and Questionnaires
Language	English
Publishing date	2023-03-07
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2023.1037699
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Article ; Online: Disease-modifying drugs for Alzheimer disease: implications for people in Canada.

Watt, Jennifer A / Isaranuwatchai, Wanrudee / Grossman, Linda / Straus, Sharon E

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

2023 Volume 195, Issue 42, Page(s) E1446–E1448

MeSH term(s)	Humans ; Alzheimer Disease/drug therapy ; Canada
Language	English
Publishing date	2023-10-30
Publishing country	Canada
Document type	Journal Article
ZDB-ID	215506-0
ISSN	1488-2329 ; 0008-4409 ; 0820-3946
ISSN (online)	1488-2329
ISSN	0008-4409 ; 0820-3946
DOI	10.1503/cmaj.230595
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Article ; Online: Pattern of OPD utilisation during the COVID-19 pandemic under the Universal Coverage Scheme in Thailand: what can 850 million records tell us?

Sukmanee, Jarawee / Butchon, Rukmanee / Karunayawong, Picharee / Saeraneesopon, Thanayut / Boonma, Chulathip / Teerawattananon, Yot / Isaranuwatchai, Wanrudee

BMC health services research

2023 Volume 23, Issue 1, Page(s) 116

Abstract: Background: Out-patient department (OPD) is a crucial component of the healthcare systems in low- and middle-income countries including Thailand. A considerable impact of coronavirus disease 2019 (COVID-19) pandemic and its control measures, especially ... ...

Abstract	Background: Out-patient department (OPD) is a crucial component of the healthcare systems in low- and middle-income countries including Thailand. A considerable impact of coronavirus disease 2019 (COVID-19) pandemic and its control measures, especially the lockdown, on utilisation of OPD services was expected. This study thus aims to estimate the pattern of OPD utilisation during the COVID-19 pandemic in Thailand including overall utilisation and within each sub-groups including diagnostic group, age group, and health region. Methods: This study was a secondary data analysis of aggregated outpatient data from patients covered under the Universal Coverage Scheme (UCS) in Thailand over a 4-year period (2017-2020). Interrupted time series analyses and segmented Quasi-Poisson regression were used to examine the impact of COVID-19 on the overall OPD utilisation including the impact on each diagnostic group, age groups, health regions, and provinces. Results: Analysis of 845,344,946 OPD visits in this study showed a seasonal pattern and increasing trend in monthly OPD visits before the COVID-19 pandemic. A 28% (rate ratio (RR) 0.718, 95% confidence interval (CI): 0.631-0.819) and 11% (RR 0.890, 95% CI: 0.811-0.977) reduction in OPD visits was observed during the lockdown and post-lockdown periods, respectively, when compared to the pre-lockdown period. Diseases of respiratory system were most affected with a RR of 0.411 (95% CI: 0.320-0.527), while the number of visits for non-communicable diseases (ICD-10: E00-E90, I00-I99) and elderly (> 60 years) dropped slightly. The post-lockdown trend in monthly OPD visits gradually increased to the pre-pandemic levels in most groups. Conclusions: Thailand's OPD utilisation rate during the COVID-19 lockdown decreased in some diseases, but the service for certain group of patients appeared to remain available. After the COVID-19 lockdown, the rate returned to the pre-pandemic level in a timely manner. Equipped with a knowledge of OPD utilisation pattern during COVID-19 based on a national real-world database could aid with a better preparation of healthcare system for future pandemics.
MeSH term(s)	Aged ; Humans ; Communicable Disease Control ; COVID-19/epidemiology ; Outpatients ; Pandemics ; Thailand/epidemiology ; Universal Health Insurance ; Interrupted Time Series Analysis ; Ambulatory Care Facilities
Language	English
Publishing date	2023-02-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2050434-2
ISSN	1472-6963 ; 1472-6963
ISSN (online)	1472-6963
ISSN	1472-6963
DOI	10.1186/s12913-023-09121-3
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Article ; Online: The impact of universal health coverage and COVID-19 pandemic on out-of-pocket expenses in Thailand: an analysis of household survey from 1994 to 2021.

Sukmanee, Jarawee / Butchon, Rukmanee / Karunayawong, Picharee / Dabak, Saudamini Vishwanath / Isaranuwatchai, Wanrudee / Teerawattananon, Yot

Expert review of pharmacoeconomics & outcomes research

2023 Volume 23, Issue 7, Page(s) 823–830

Abstract: Objectives: After Thailand achieved Universal Health Coverage (UHC) in 2002, the extent of financial risk protection has not been assessed in the long term, especially after the COVID-19 pandemic. Therefore, this study aims to revisit the impact of UHC ... ...

Abstract	Objectives: After Thailand achieved Universal Health Coverage (UHC) in 2002, the extent of financial risk protection has not been assessed in the long term, especially after the COVID-19 pandemic. Therefore, this study aims to revisit the impact of UHC on out-of-pocket expenses (OOPE) for health and to descriptively explore the impact of COVID-19 on OOPE. Methods: This study was a secondary data analysis and used data from the Socio-Economic Survey from 1994 to 2021 in Thailand. The effect of UHC on the percentage of OOPE in total health expenditures (THE) from 1994 to 2019 was investigated with an interrupted time-series analysis. Descriptive analyses of OOPE in absolute value during the COVID-19 were conducted. Results: The percentage of OOPE in THE significantly decreased both before (β -2.02%; 95% CI: -2.70% to - 1.33%) and during (β 1.41%; 95% CI: 0.70% to 2.11%) the UHC period. During the pandemic, total household OOPE for medical equipment was found to have rapidly increased from 643 million THB in 2019 to 9.4 billion THB in 2020. Conclusions: The trend of providing financial risk protection (measured by OOPE/THE) in Thailand continues until 2019. Providing medical equipment in sufficient and equally accessible manners should be prioritized during the future pandemic.
MeSH term(s)	Humans ; Health Expenditures ; Pandemics ; Universal Health Insurance ; Thailand ; COVID-19
Language	English
Publishing date	2023-06-05
Publishing country	England
Document type	Journal Article
ZDB-ID	2208481-2
ISSN	1744-8379 ; 1473-7167
ISSN (online)	1744-8379
ISSN	1473-7167
DOI	10.1080/14737167.2023.2219447
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Article: Impact of Preoperative Anemia on the Healthcare Cost of a Hysterectomy.

Bakhache, Nour / Shirreff, Lindsay / Matelski, John / Loong, Desmond / Isaranuwatchai, Wanrudee / Murji, Ally

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC

2023 Volume 46, Issue 1, Page(s) 102230

MeSH term(s)	Female ; Humans ; Hysterectomy ; Anemia/therapy ; Health Care Costs
Language	English
Publishing date	2023-09-22
Publishing country	Netherlands
Document type	Letter
ZDB-ID	2171082-X
ISSN	1701-2163
ISSN	1701-2163
DOI	10.1016/j.jogc.2023.102230
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Article ; Online: COVID-19 Vaccine Hesitancy Among Health Care Workers in Thailand: The Comparative Results of Two Cross-Sectional Online Surveys Before and After Vaccine Availability.

Pheerapanyawaranun, Chatkamol / Wang, Yi / Kittibovorndit, Nachawish / Pimsarn, Nopphadol / Sirison, Kanchanok / Teerawattananon, Yot / Isaranuwatchai, Wanrudee

Frontiers in public health

2022 Volume 10, Page(s) 834545

Abstract: Introduction: The arrival of COVID-19 vaccines in Thailand has supported the fight against the COVID-19 pandemic. This study examined COVID-19 vaccine acceptance among health care workers (HCWs) in Thailand before and after vaccines' availability and ... ...

Abstract	Introduction: The arrival of COVID-19 vaccines in Thailand has supported the fight against the COVID-19 pandemic. This study examined COVID-19 vaccine acceptance among health care workers (HCWs) in Thailand before and after vaccines' availability and investigated factors (both enablers and barriers) affecting their decisions. Methods: Two online self-administered questionnaires were distributed to HCWs in two time-periods: (1) the pre-vaccine arrival period (prior to COVID-19 vaccines' arrival in Thailand, January 28 to February 16, 2021); and (2) the post-vaccine arrival period (April 21 to May 9, 2021). Descriptive analyses and multinomial logistic regression were conducted to examine factors associated with vaccine hesitancy. Results: There were 55,068 respondents in the pre-vaccine arrival period and 27,319 respondents in the post-vaccine arrival period. In the pre-vaccine arrival period, 55.0% of respondents were willing to accept the vaccines, 35.4% were uncertain, and 9.6% declined. In the post-vaccine arrival period, ~16% already received two doses of either the Sinovac or AstraZeneca vaccine, and 43% were administered one dose. Approximately 12% of those who had received the first dose were uncertain or not willing to accept the second dose. Demographic and socio-demographic factors of participants, including their sex, place of residence, and whether they were frontline COVID-19 workers, were found to be the significant factors explaining vaccination hesitancy. Moreover, when comparing the pre-vaccine arrival and post-vaccine arrival periods, it was found that older HCWs were more likely to decline a COVID-19 vaccine in the pre-vaccine arrival period; on the other hand, older HCWs were less likely to decline or be uncertain to receive a COVID-19 vaccine in the post-vaccine arrival period. Conclusion: Information on HCWs' acceptance of COVID-19 vaccines, including who is more likely to accept the vaccines, could assist in planning vaccine allocation to both HCWs and the general public, who often believe HCWs' recommendations. This study's findings set out how policies can be addressed to reduce vaccine hesitancy. This study also highlights HCWs' characteristics (including gender, work region, occupation, and history of receiving influenza vaccination) and the reasons they cited for their vaccine acceptance or hesitance.
MeSH term(s)	Attitude of Health Personnel ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines/therapeutic use ; Cross-Sectional Studies ; Health Personnel ; Humans ; Influenza Vaccines ; Influenza, Human ; Pandemics/prevention & control ; Patient Acceptance of Health Care ; Surveys and Questionnaires ; Thailand ; Vaccination Hesitancy
Chemical Substances	COVID-19 Vaccines ; Influenza Vaccines
Language	English
Publishing date	2022-08-01
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2022.834545
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Article: What is the value of explicit priority setting for health interventions? A simulation study.

Barlow, Euan / Morton, Alec / Dabak, Saudamini / Engels, Sven / Isaranuwatchai, Wanrudee / Teerawattananon, Yot / Chalkidou, Kalipso

Health care management science

2022 Volume 25, Issue 3, Page(s) 460–483

Abstract: Many countries seek to secure efficiency in health spending through establishing explicit priority setting institutions (PSIs). Since such institutions divert resources from frontline services which benefit patients directly, it is legitimate and ... ...

Abstract	Many countries seek to secure efficiency in health spending through establishing explicit priority setting institutions (PSIs). Since such institutions divert resources from frontline services which benefit patients directly, it is legitimate and reasonable to ask whether they are worth the money. We address this question by comparing, through simulation, the health benefits and costs from implementing two alternative funding approaches - one scenario in which an active PSI enables cost-effectiveness-threshold based funding decisions, and a counterfactual scenario where there is no PSI. We present indicative results for one dataset from the United Kingdom (published in 2015) and one from Malawi (published in 2018), which show that the threshold rule reliably resulted in decreased health system costs, improved health benefits, or both. Our model is implemented in Microsoft Excel and designed to be user-friendly, and both the model and a user guide are made publicly available, in order to enable others to parameterise the model based on the local setting. Although inevitably stylised, we believe that our modelling and results offer a valid perspective on the added value of explicit PSIs.
MeSH term(s)	Computer Simulation ; Cost-Benefit Analysis ; Humans ; United Kingdom
Language	English
Publishing date	2022-05-28
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1469148-6
ISSN	1572-9389 ; 1386-9620
ISSN (online)	1572-9389
ISSN	1386-9620
DOI	10.1007/s10729-022-09594-4
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Article: Expanding access to high-cost medicines under the Universal Health Coverage scheme in Thailand: review of current practices and recommendations.

Butani, Dimple / Faradiba, Dian / Dabak, Saudamini Vishwanath / Isaranuwatchai, Wanrudee / Huang-Ku, Evan / Pachanee, Kumaree / Soboon, Budsadee / Culyer, Anthony J / Teerawattananon, Yot

Journal of pharmaceutical policy and practice

2023 Volume 16, Issue 1, Page(s) 138

Abstract: Background: There has been an increasing demand to reimburse high-cost medicines, through public health insurance schemes in Thailand.: Methods: A mixed method approach was employed. First, a rapid review of select high-income countries was conducted, ...

Abstract	Background: There has been an increasing demand to reimburse high-cost medicines, through public health insurance schemes in Thailand. Methods: A mixed method approach was employed. First, a rapid review of select high-income countries was conducted, followed by expert consultations and an in-depth review of three countries: Australia, England and Republic of Korea to understand reimbursement mechanisms of high-cost medicines. In Thailand, current pathways for reimbursing high-cost medicines reviewed, the potential opportunity cost estimated, and stakeholder consultations were conducted to identify context specific considerations. Results: High-income countries reviewed have implemented a variety of pathways and mechanisms for reimbursing high-cost medicines under specific eligibility criteria, listing processes, varying cost-effectiveness thresholds and special funding arrangements. In Thailand, high-cost medicines that do not offer good value-for-money are excluded from the reimbursement process. A framework for reimbursing high-cost medicines that are not cost-effective at the current willingness-to-pay threshold was proposed for Thailand. Under this framework, specific criteria are proposed to determine their eligibility for reimbursement such life-saving nature, treatment of conditions with no alternative treatment options, and affordability. Conclusion: High-cost medicines may become eligible for reimbursement through alternative mechanisms based on specific criteria which depend on each context. The application of HTA methods and processes is important in guiding these decisions to support sustainable access to affordable healthcare in pursuit of Universal Health Coverage (UHC).
Language	English
Publishing date	2023-11-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2734772-2
ISSN	2052-3211
ISSN	2052-3211
DOI	10.1186/s40545-023-00643-z
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