LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Back to previous search Search history
Advanced search

Your last searches

  1. AU="Ishihara, Hiromasa"
  2. AU="Tayana, Ngampuk"
  3. AU=MacKinlay Andrew
  4. AU="Henninger, Jonathan E"
  5. AU="Bulfone-Paus, Silvia"
  6. AU="Anderson, Rebecca"
  7. AU="Diehr P"
  8. AU="Jensen, Aaron M"
  9. AU="Pitsavos, Christos"

Search results

Result 1 - 5 of total 5

Search options

  1. Article ; Online: Changes in serum DAMPs and cytokines/chemokines during near-infrared photoimmunotherapy for patients with head and neck cancer.

    Ishihara, Hiromasa / Nishikawa, Daisuke / Muraoka, Daisuke / Masago, Katsuhiro / Beppu, Shintaro / Terada, Hoshino / Matsushita, Hirokazu / Hanai, Nobuhiro

    Cancer medicine

    2023  

    Abstract: Background: Near-infrared photoimmunotherapy (NIR-PIT) for head and neck cancer is a recently developed therapy. However, there is limited data on patients receiving NIR-PIT in real clinical settings.: Methods: Seven NIR-PIT sessions were ... ...

    Abstract Background: Near-infrared photoimmunotherapy (NIR-PIT) for head and neck cancer is a recently developed therapy. However, there is limited data on patients receiving NIR-PIT in real clinical settings.
    Methods: Seven NIR-PIT sessions were administered to five patients with head and neck squamous cell carcinoma (HNSCC). Serum damage-associated molecular patterns (DAMPs) (HMGB1 and Hsp70 levels), and cytokine and chemokine production, were compared before and after NIR-PIT.
    Results: The serum concentration of HMGB1 increased after NIR-PIT (p = 0.031, Wilcoxon test) in all patients except one who did not achieve a clinical response. Chemokines MIP-1α (CCL3) and MIP-1β (CCL4) increased significantly 1-3 days after treatment (CCL3, p = 0.0036; CCL4, p = 0.0016, Wilcoxon test). A low pre-treatment neutrophil-to-lymphocyte ratio (NLR) was associated with a better response to therapy and survival.
    Conclusions: The release of DAMPs, and cytokine/chemokine production, were detected in the patients' peripheral blood. The baseline NLR may predict patient outcomes in response to NIR-PIT.
    Language English
    Publishing date 2023-12-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2659751-2
    ISSN 2045-7634 ; 2045-7634
    ISSN (online) 2045-7634
    ISSN 2045-7634
    DOI 10.1002/cam4.6863
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Hearing loss is associated with hippocampal atrophy and high cortisol/dehydroepiandrosterone sulphate ratio in older adults.

    Aoki, Mitsuhiro / Okuda, Hiroshi / Ishihara, Hiromasa / Hayashi, Hisamitsu / Ohashi, Toshimitsu / Nishihori, Takesumi / Kuze, Bunya

    International journal of audiology

    2020  Volume 60, Issue 4, Page(s) 293–299

    Abstract: Objectives: Hearing loss (HL) has been recognised as a prodromal symptom of cognitive disorder with aging. It is still uncertain if HL leads to cognitive impairment directly or through an indirect mechanism.: Design: Participants of this study ... ...

    Abstract Objectives: Hearing loss (HL) has been recognised as a prodromal symptom of cognitive disorder with aging. It is still uncertain if HL leads to cognitive impairment directly or through an indirect mechanism.
    Design: Participants of this study underwent an auditory test, blood tests, and brain MRI. The atrophy rate of the hippocampus (HP) was calculated using voxel-based specific areas. A partial correlation analysis whilst controlling for the effect of age was performed to analyse the factors affecting hearing levels and HP atrophy rate (HP%).
    Study sample: Thirty-six older adults with hearing impairment.
    Results: The group of participants with moderate or severe HL (
    Conclusions: Our results suggest that the HL is associated with the atrophy of HP and high C/D ratios in older adults; however, HL may not be causally related to hippocampal atrophy.
    MeSH term(s) Aged ; Atrophy ; Dehydroepiandrosterone Sulfate ; Hearing Loss/diagnosis ; Hippocampus/diagnostic imaging ; Humans ; Hydrocortisone
    Chemical Substances Dehydroepiandrosterone Sulfate (57B09Q7FJR) ; Hydrocortisone (WI4X0X7BPJ)
    Language English
    Publishing date 2020-10-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2073098-6
    ISSN 1708-8186 ; 1499-2027
    ISSN (online) 1708-8186
    ISSN 1499-2027
    DOI 10.1080/14992027.2020.1831703
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 549: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: MRI findings of epithelial-myoepithelial carcinoma of the parotid gland with radiologic-pathologic correlation.

    Suto, Taketo / Kato, Hiroki / Kawaguchi, Masaya / Kobayashi, Kazuhiro / Miyazaki, Tatsuhiko / Ando, Tomohiro / Noda, Yoshifumi / Hyodo, Fuminori / Matsuo, Masayuki / Ishihara, Hiromasa / Ogawa, Takenori

    Japanese journal of radiology

    2022  Volume 40, Issue 6, Page(s) 578–585

    Abstract: Purpose: This study aimed to describe the MRI findings of epithelial-myoepithelial carcinoma (EMC) of the parotid gland.: Materials and methods: Seven patients (four males and three females) aged 40-86 years (mean age, 64 years) with histologically ... ...

    Abstract Purpose: This study aimed to describe the MRI findings of epithelial-myoepithelial carcinoma (EMC) of the parotid gland.
    Materials and methods: Seven patients (four males and three females) aged 40-86 years (mean age, 64 years) with histologically proven EMC of the parotid gland who underwent surgical resection after preoperative MRI were enrolled. MRI images were retrospectively reviewed and contrasted with pathological findings.
    Results: Five patients (71%) had predominantly solid lesions, and two (29%) had predominantly cystic lesions. All seven lesions had well-demarcated margins and capsules without the invasion of adjacent structures. The capsules were incomplete in five lesions (71%) and complete in two (29%). Four lesions (57%) exhibited a multinodular structure with internal septa. Cystic components were observed in three lesions (43%). On T1-weighted images, the solid components were frequently homogeneous (5/7, 71%), and demonstrated isointensity in five lesions (71%) and hypointensity in two (29%) relative to the spinal cord. On T2-weighted images, the solid components were usually heterogeneous (6/7, 86%), and demonstrated hyperintensity in five lesions (71%) and isointensity in two (29%) relative to the spinal cord. The mean apparent diffusion coefficient value of the solid components was 0.967 × 10
    Conclusion: Parotid gland EMCs usually appeared as predominantly solid lesions with well-demarcated margins and capsules. A multinodular structure with internal septa was characteristics of EMCs.
    MeSH term(s) Capsules ; Carcinoma ; Female ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Parotid Gland/diagnostic imaging ; Parotid Gland/pathology ; Parotid Gland/surgery ; Parotid Neoplasms/diagnostic imaging ; Parotid Neoplasms/pathology ; Parotid Neoplasms/surgery ; Retrospective Studies
    Chemical Substances Capsules
    Language English
    Publishing date 2022-01-04
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2488907-6
    ISSN 1867-108X ; 1867-1071
    ISSN (online) 1867-108X
    ISSN 1867-1071
    DOI 10.1007/s11604-021-01243-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2249: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Obesity does not affect peri- and postoperative outcomes of transabdominal laparoscopic adrenalectomy.

    Inaishi, Takahiro / Kikumori, Toyone / Takeuchi, Dai / Ishihara, Hiromasa / Miyajima, Noriyuki / Shibata, Masahiro / Takano, Yuko / Nakanishi, Kenichi / Noda, Sumiyo / Kodera, Yasuhiro

    Nagoya journal of medical science

    2018  Volume 80, Issue 1, Page(s) 21–28

    Abstract: Laparoscopic adrenalectomy is the gold standard procedure for most adrenal tumors. Obesity is considered as a risk factor for surgical complications. This study aimed to evaluate whether obesity affects peri- and postoperative outcomes of transabdominal ... ...

    Abstract Laparoscopic adrenalectomy is the gold standard procedure for most adrenal tumors. Obesity is considered as a risk factor for surgical complications. This study aimed to evaluate whether obesity affects peri- and postoperative outcomes of transabdominal laparoscopic adrenalectomy using body mass index (BMI). This retrospective study included 98 patients who underwent transabdominal laparoscopic adrenalectomy between January 2011 and December 2016. We divided the patients into 2 groups: non-obese group (BMI < 25 kg/m2) and obese group (BMI ≥ 25 kg/m2). We assessed perioperative outcomes and postoperative complications between the groups. A total of 98 patients were analyzed (70 without obesity and 28 with obesity). There were no significant differences between the non-obese and obese groups regarding operative time (111 vs 107 min; p = 0.795), blood loss (3.5 vs 3.5 ml; p = 0.740), rate of placement of additional trocars (14.3% vs 17.9%; p = 0.657), rate of open conversion (2.6% vs 3.6%; p = 0.853), and postoperative length of hospital stay (6 vs 5 days; p = 0.237). Furthermore, obesity was not a significant risk factor for postoperative complications (postoperative bleeding, wound infection, and pneumonia). There are no significant differences in peri- and postoperative outcomes of transabdominal laparoscopic adrenalectomy in patients with obesity compared with those without obesity. Transabdominal laparoscopic adrenalectomy is feasible and safe for patients with obesity.
    MeSH term(s) Adolescent ; Adrenal Glands/surgery ; Adrenalectomy/methods ; Adult ; Aged ; Body Mass Index ; Female ; Humans ; Laparoscopy/methods ; Male ; Middle Aged ; Obesity/complications ; Obesity/surgery ; Postoperative Complications ; Retrospective Studies ; Treatment Outcome ; Young Adult
    Language English
    Publishing date 2018-03-26
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 193148-9
    ISSN 2186-3326 ; 0027-7622
    ISSN (online) 2186-3326
    ISSN 0027-7622
    DOI 10.18999/nagjms.80.1.21
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.181: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: A resected case of symptomatic acinar cell cystadenoma of the pancreas displacing the main pancreatic duct.

    Tanaka, Haruyoshi / Hatsuno, Tsuyoshi / Kinoshita, Mitsuru / Hasegawa, Kazuya / Ishihara, Hiromasa / Takano, Nao / Shimoyama, Satofumi / Nakayama, Hiroshi / Kataoka, Masato / Ichihara, Shu / Kanda, Mitsuro / Kodera, Yasuhiro / Kondo, Ken

    Surgical case reports

    2016  Volume 2, Issue 1, Page(s) 39

    Abstract: Acinar cell cystadenoma (ACA) of the pancreas has been newly recognized as an entity by the World Health Organization (WHO) definition (2010), and its pathogenesis has not been known adequately because of the rarity. Here, we report a case of a 22-year- ... ...

    Abstract Acinar cell cystadenoma (ACA) of the pancreas has been newly recognized as an entity by the World Health Organization (WHO) definition (2010), and its pathogenesis has not been known adequately because of the rarity. Here, we report a case of a 22-year-old female who had been followed up for a cystic lesion at the tail of the pancreas pointed out by a screening computed tomography (CT) scan 7 years ago. The tumor grew in size from 3.3 to 5.1 cm in diameter for 6 years (0.3 cm per year). Particularly, it rapidly grew up to 6.3 cm in the latest 3 months in concurrence with the emergence of epigastralgia. A contrasted CT scan revealed the irregularly formed, multilocular cystic tumor having thin septum and calcification. The intratumoral magnetic resonance imaging intensity in the T1 and T2 weighted images were low and high, respectively. No communications between the tumor and the main pancreatic duct (MPD) were found, but the tumor displaced the MPD. She underwent surgical resection because the tumor was growing, turned symptomatic, and it seemed difficult to be diagnosed correctly until totally biopsied. Spleen-preserved distal pancreatectomy was performed. It was pathologically diagnosed as ACA; the cyst was lined by cells with normal acinar differentiation; cuboidal cells with round, basally oriented nuclei and eosinophilic granules in its apical cytoplasm. The abdominal pain has disappeared, and no recurrences have been found during a 5-year follow-up. Clinicians are recommended to consider an ACA as one of differential diagnoses of cystic tumors of the pancreas to provide appropriate diagnostics and therapeutics.
    Language English
    Publishing date 2016-04-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2809613-7
    ISSN 2198-7793
    ISSN 2198-7793
    DOI 10.1186/s40792-016-0166-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top