LIVIVO - Search results -

Search results

Result 1 - 10 of total 102

Search options

Article ; Online: Inhibition of Aflatoxin Production in

Sakuda, Shohei / Sunaoka, Masaki / Terada, Maho / Sakoda, Ayaka / Ishijima, Natsumi / Hakoshima, Noriko / Uchida, Kenichi / Enomoto, Hirofumi / Furukawa, Tomohiro

Toxins

2024 Volume 16, Issue 3

Abstract: During an experiment where we were cultivating ... ...

Abstract	During an experiment where we were cultivating aflatoxigenic
MeSH term(s)	Aspergillus flavus ; Aflatoxins ; Klebsiella ; Dipeptides ; Arachis ; Glutathione Transferase
Chemical Substances	Aflatoxins ; alanylglycine (687-69-4) ; Dipeptides ; Glutathione Transferase (EC 2.5.1.18)
Language	English
Publishing date	2024-03-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518395-3
ISSN	2072-6651 ; 2072-6651
ISSN (online)	2072-6651
ISSN	2072-6651
DOI	10.3390/toxins16030141
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Combined usage of serodiagnosis and O antigen typing to isolate Shiga toxin-producing

Lee, Kenichi / Iguchi, Atsushi / Terano, Chikako / Hataya, Hiroshi / Isobe, Junko / Seto, Kazuko / Ishijima, Nozomi / Akeda, Yukihiro / Ohnishi, Makoto / Iyoda, Sunao

Microbiology spectrum

2023 Volume 12, Issue 1, Page(s) e0235523

Abstract: Importance: Hemolytic uremic syndrome (HUS) is a life-threatening disease caused by Shiga toxin- ... ...

Abstract	Importance: Hemolytic uremic syndrome (HUS) is a life-threatening disease caused by Shiga toxin-producing
MeSH term(s)	Humans ; Shiga Toxin/genetics ; O Antigens/genetics ; Shiga-Toxigenic Escherichia coli ; Serotyping/methods ; Hemolytic-Uremic Syndrome/diagnosis ; Escherichia coli Infections/diagnosis ; Genomics ; Serologic Tests
Chemical Substances	Shiga Toxin (75757-64-1) ; O Antigens
Language	English
Publishing date	2023-12-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	2807133-5
ISSN	2165-0497 ; 2165-0497
ISSN (online)	2165-0497
ISSN	2165-0497
DOI	10.1128/spectrum.02355-23
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Enhancing the photovoltaic performance of hybrid heterojunction solar cells by passivation of silicon surface via a simple 1-min annealing process.

Xie, Rongbin / Ishijima, Naoya / Sugime, Hisashi / Noda, Suguru

Scientific reports

2019 Volume 9, Issue 1, Page(s) 12051

Abstract: Solution-based heterojunction technology is emerging for facile fabrication of silicon (Si)-based solar cells. Surface passivation of Si substrate has been well established to improve the photovoltaic (PV) performance for the conventional bulk Si cells. ... ...

Abstract	Solution-based heterojunction technology is emerging for facile fabrication of silicon (Si)-based solar cells. Surface passivation of Si substrate has been well established to improve the photovoltaic (PV) performance for the conventional bulk Si cells. However, the impact is still not seen for the heterojunction cells. Here, we developed a facile and repeatable method to passivate the Si surface by a simple 1-min annealing process in vacuum, and integrated it into the heterojunction cells with poly(3,4-ethylenedioxythiophene): poly(styrenesulfonate) (PEDOT:PSS) or carbon nanotube (CNT). A thin and dense oxide layer was introduced on the Si surface to provide a high-quality hole transport layer and passivation layer. The layer enhanced the power conversion efficiency from 9.34% to 12.87% (1.38-times enhancement) for the PEDOT:PSS/n-Si cells and from 6.61% to 8.52% (1.29-times enhancement) for the CNT/n-Si cells. The simple passivation is a promising way to enhance the PV performance of the Si cells with various solution-based heterojunctions.
Language	English
Publishing date	2019-08-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-019-48504-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Increased resistance against tellurite is conferred by a mutation in the promoter region of uncommon tellurite resistance gene

Matsumoto, Yuko / Lee, Kenichi / Akasaka, Ryuya / Honjo, Hayato / Koizumi, Mitsumasa / Sato, Toshio / Kubomura, Akiko / Ishijima, Nozomi / Akeda, Yukihiro / Ohnishi, Makoto / Iyoda, Sunao

Applied and environmental microbiology

2024 , Page(s) e0228323

Abstract: Resistance to potassium tellurite (PT) is an important indicator in isolating Shiga toxin-producing : Importance: Selective agents are important for isolating Shiga toxin- ... ...

Abstract	Resistance to potassium tellurite (PT) is an important indicator in isolating Shiga toxin-producing Importance: Selective agents are important for isolating Shiga toxin-producing
Language	English
Publishing date	2024-05-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	223011-2
ISSN	1098-5336 ; 0099-2240
ISSN (online)	1098-5336
ISSN	0099-2240
DOI	10.1128/aem.02283-23
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 201: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Multiple-Locus Variable-Number Tandem Repeat Analysis Scheme for Non-O157 Shiga Toxin-Producing Escherichia coli: Focus on Serogroups O103, O121, O145, O165, and O91.

Izumiya, Hidemasa / Lee, Kenichi / Ishijima, Nozomi / Iyoda, Sunao / Ohnishi, Makoto

Japanese journal of infectious diseases

2020 Volume 73, Issue 6, Page(s) 481–490

Abstract: Non-O157 Shiga toxin-producing Escherichia coli (STEC) infections are a growing concern for public health. The number of sporadic cases and outbreaks of non-O157 STEC infections have increased in recent years. Molecular subtyping is an essential tool ... ...

Abstract	Non-O157 Shiga toxin-producing Escherichia coli (STEC) infections are a growing concern for public health. The number of sporadic cases and outbreaks of non-O157 STEC infections have increased in recent years. Molecular subtyping is an essential tool that allows high-resolution and rapid differentiation of isolates, identification of case clusters, and detection of outbreak clusters. Multiple-locus variable-number tandem repeat analysis (MLVA) is one of the most useful typing methods for differentiating isolates that cause foodborne diseases. In Japan, serogroups O26, O111, O103, O121, O145, O165, and O91 have been frequently isolated or associated with severe cases of non-O157 STEC infections. In this study, we designed an MLVA scheme (MLVA43) for serogroups O103, O121, O145, O165, and O91 by adding 26 new loci to an MLVA scheme (MLVA17) previously developed by our group for serogroups O157, O26, and O111 using 17 loci. We found that the discriminatory power of MLVA43 was comparable to that of pulsed-field gel electrophoresis (PFGE) for serogroups O103, O145, O165, and O91, and superior to that of PFGE for O121. MLVA43 identified more profiles than did MLVA17, except for serogroup O111 with 707 isolates. The MLVA43 scheme will enable rapid detection of outbreak clusters, which will aid in implementing rapid control measures against non-O157 STEC infections.
MeSH term(s)	DNA, Bacterial/analysis ; DNA, Bacterial/genetics ; Electrophoresis, Gel, Pulsed-Field/methods ; Escherichia coli Infections/microbiology ; Escherichia coli O157/genetics ; Genome, Bacterial ; Humans ; Japan ; Minisatellite Repeats/genetics ; Multilocus Sequence Typing/methods ; Serogroup ; Shiga-Toxigenic Escherichia coli/classification ; Shiga-Toxigenic Escherichia coli/genetics ; Shiga-Toxigenic Escherichia coli/isolation & purification ; Whole Genome Sequencing/methods
Chemical Substances	DNA, Bacterial
Language	English
Publishing date	2020-06-30
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1478383-6
ISSN	1884-2836 ; 1344-6304
ISSN (online)	1884-2836
ISSN	1344-6304
DOI	10.7883/yoken.JJID.2020.095
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ua VI Zs.409: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Regulation of constant cell elongation and Sfm pili synthesis in Escherichia coli via two active forms of FimZ orphan response regulator.

Ogawa, Ayano / Kojima, Fumika / Miyake, Yukari / Yoshimura, Miho / Ishijima, Nozomi / Iyoda, Sunao / Sekine, Yasuhiko / Yamanaka, Yuki / Yamamoto, Kaneyoshi

Genes to cells : devoted to molecular & cellular mechanisms

2022 Volume 27, Issue 11, Page(s) 657–674

Abstract: Escherichia coli (E. coli) has multiple copies of the chaperone-usher (CU) pili operon in five fimbria groups: CU pili, curli, type IV pili, type III secretion pili, and type IV secretion pili. Commensal E. coli K-12 contains 12 CU pili operons. Among ... ...

Abstract	Escherichia coli (E. coli) has multiple copies of the chaperone-usher (CU) pili operon in five fimbria groups: CU pili, curli, type IV pili, type III secretion pili, and type IV secretion pili. Commensal E. coli K-12 contains 12 CU pili operons. Among these operons, Sfm is expressed by the sfmACDHF operon. Transcriptome analyses, reporter assays, and chromatin immunoprecipitation PCR analyses reported that FimZ directly binds to and activates the sfmA promoter, transcribing sfmACDHF. In addition, FimZ regularly induces constant cell elongation in E. coli, which is required for F-type ATPase function. The bacterial two-hybrid system showed a specific interaction between FimZ and the α subunit of the cytoplasmic F
MeSH term(s)	Escherichia coli/genetics ; Escherichia coli/metabolism ; Fimbriae Proteins/genetics ; Fimbriae Proteins/metabolism ; Gene Expression Regulation, Bacterial ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; Molecular Chaperones/genetics ; Adenosine Triphosphatases/genetics
Chemical Substances	Fimbriae Proteins (147680-16-8) ; Bacterial Proteins ; Escherichia coli Proteins ; Molecular Chaperones ; Adenosine Triphosphatases (EC 3.6.1.-)
Language	English
Publishing date	2022-09-18
Publishing country	England
Document type	Journal Article
ZDB-ID	1330000-3
ISSN	1365-2443 ; 1356-9597
ISSN (online)	1365-2443
ISSN	1356-9597
DOI	10.1111/gtc.12982
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 4539: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Activation of AMP-activated protein kinase by retinoic acid sensitizes hepatocellular carcinoma cells to apoptosis induced by sorafenib.

Ishijima, Naoki / Kanki, Keita / Shimizu, Hiroki / Shiota, Goshi

Cancer science

2015 Volume 106, Issue 5, Page(s) 567–575

Abstract: To improve the outcome of cancer chemotherapy, strategies to enhance the efficacy of anticancer drugs are required. Sorafenib is the only drug to prolong overall survival of the patients with hepatocellular carcinoma (HCC), however, the outcome is still ... ...

Abstract	To improve the outcome of cancer chemotherapy, strategies to enhance the efficacy of anticancer drugs are required. Sorafenib is the only drug to prolong overall survival of the patients with hepatocellular carcinoma (HCC), however, the outcome is still not satisfactory. Retinoids, vitamin A derivatives, have been known to exhibit inhibitory effects on various cancers including HCC. In this study, we investigated the effects of combined treatment using sorafenib and retinoids including all-trans retinoic acid (ATRA), NIK-333, and Am80 on HCC cells. Cell viability assays in six HCC cell lines, HepG2, PLC/PRF/5, HuH6, HLE, HLF, and Hep3B, revealed that 5 and 10 μM ATRA, concentrations that do not exert cytotoxic effects, enhanced the cytotoxicity of sorafenib, being much more effective than NIK-333 and Am80. We found that ATRA induced AMP-activated protein kinase activation, which was followed by reduced intracellular ATP level. Gene expression analysis revealed that ATRA decreased the expression of glycolytic genes such as GLUT-1 and LDHA. In the combination treatment using ATRA and sorafenib, increased apoptosis, followed by the activation of p38 MAPK and JNK, the upregulation and translocation of Bax to mitochondria, and the activation of caspase-3, was observed. Suppression of AMP-activated protein kinase by siRNA restored the viability of the cells treated with ATRA and sorafenib. Our results thus indicate that ATRA is useful for enhancing the cytotoxicity of sorafenib against HCC cells by regulating the energy metabolism of HCC cells.
MeSH term(s)	AMP-Activated Protein Kinases/metabolism ; Adenosine Triphosphate/metabolism ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Apoptosis/drug effects ; Benzoates/administration & dosage ; Benzoates/pharmacology ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Glucose Transporter Type 1/genetics ; Humans ; Liver Neoplasms/drug therapy ; Liver Neoplasms/pathology ; Niacinamide/administration & dosage ; Niacinamide/analogs & derivatives ; Niacinamide/pharmacology ; Phenylurea Compounds/administration & dosage ; Phenylurea Compounds/pharmacology ; Retinoids/administration & dosage ; Retinoids/pharmacology ; Tetrahydronaphthalenes/administration & dosage ; Tetrahydronaphthalenes/pharmacology ; Tretinoin/administration & dosage ; Tretinoin/pharmacology ; bcl-2-Associated X Protein/metabolism
Chemical Substances	BAX protein, human ; Benzoates ; Glucose Transporter Type 1 ; Phenylurea Compounds ; Retinoids ; SLC2A1 protein, human ; Tetrahydronaphthalenes ; bcl-2-Associated X Protein ; tamibarotene (08V52GZ3H9) ; (2E,4E,6E,10E)-3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid (11ALM7A4RV) ; Niacinamide (25X51I8RD4) ; Tretinoin (5688UTC01R) ; Adenosine Triphosphate (8L70Q75FXE) ; sorafenib (9ZOQ3TZI87) ; AMP-Activated Protein Kinases (EC 2.7.11.31)
Language	English
Publishing date	2015-05
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1349-7006
ISSN (online)	1349-7006
DOI	10.1111/cas.12633
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Full text

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- Full text online
- Order with fees

Article: Toxic characteristics of the synthetic lipid A derivative DT-5461 in rats and monkeys.

Sagara-Ishijima, N / Furuhama, K

Toxicological sciences : an official journal of the Society of Toxicology

1999 Volume 49, Issue 2, Page(s) 324–331

Abstract: We compared lethal toxicity and potential for splenomegaly and disseminated intravascular coagulation (DIC) of the lipid A derivative DT-5461 with those of compound 506 (C506) and bacterial lipopolysaccharide (LPS). These agents were given intravenously, ...

Abstract	We compared lethal toxicity and potential for splenomegaly and disseminated intravascular coagulation (DIC) of the lipid A derivative DT-5461 with those of compound 506 (C506) and bacterial lipopolysaccharide (LPS). These agents were given intravenously, by either bolus intravenous injection (2 ml/min) or drip infusion (3 ml/4 h), into the tail vein of rats under various regimens. In naive rats, the lethal dose after bolus intravenous injection was clearly higher than that after drip infusion for C506 and LPS, but not for DT-5461. In partially hepatectomized or D-galactosamine-treated rats, a marked enhancement of the lethality was observed for all agents relative to that in naive rats. Splenomegaly was commonly seen in all surviving rats after treatment, and histopathological examination revealed lymphoid hyperplasia in the B-cell area of the white pulp zone and lympho-reticular cell proliferation of the red pulp zone. When administered intravenously by drip infusion to rats pretreated with 0.4 M lactic acid, both C506 and LPS provoked DIC. This was manifested by a decrease in platelet counts, prolongation of activated partial thromboplastin time (APTT), and an increase in fibrin-fibrinogen degradation products (FDP), with hepatocellular necrosis and glomercular fibrin thrombus formation. In contrast, DT-5461 showed no such toxic events with the same protocol. In14-day intravenous toxicity studies of DT-5461, rats were more susceptible to hepatocellular necrosis and splenomegaly than squirrel monkeys. These results demonstrate that DT-5461 is a promising compound, with antitumor activity dissociated from its toxic potential.
MeSH term(s)	Animals ; Disaccharides/administration & dosage ; Disaccharides/toxicity ; Disseminated Intravascular Coagulation/chemically induced ; Hyperplasia/chemically induced ; Lipid A/administration & dosage ; Lipid A/analogs & derivatives ; Lipid A/toxicity ; Lipopolysaccharides/toxicity ; Male ; Rats ; Rats, Sprague-Dawley ; Saimiri ; Species Specificity ; Splenomegaly/chemically induced ; Splenomegaly/mortality ; Splenomegaly/pathology ; Survival Rate
Chemical Substances	Disaccharides ; Lipid A ; Lipopolysaccharides ; DT 5461 (123598-19-6)
Language	English
Publishing date	1999-06
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	1420885-4
ISSN	1096-0929 ; 1096-6080
ISSN (online)	1096-0929
ISSN	1096-6080
DOI	10.1093/toxsci/49.2.324
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1709: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Blood transfusion and postoperative serum interleukin-6 levels in colorectal cancer patients.

Ishijima, N / Suzuki, H

Hepato-gastroenterology

1998 Volume 45, Issue 22, Page(s) 1011–1013

Abstract: Background/aims: Postoperative cytokine response affects various factors. However, excessive stress responses are deleterious as increased serum concentration of cytokines may induce tissue injury and an impaired immune system.: Methodology: We ... ...

Abstract	Background/aims: Postoperative cytokine response affects various factors. However, excessive stress responses are deleterious as increased serum concentration of cytokines may induce tissue injury and an impaired immune system. Methodology: We determined serum IL-6 levels in 35 patients who had undergone resection of colorectal carcinoma. Eleven patients had a blood transfusion before or during the operation (transfused group) but 24 patients had received no blood transfusion (control group). Serum IL-6 levels were determined before the operation, and at the end of operation,POD-1, 3, and 7. Results: There was no significant difference of preoperative mean levels of IL-6 between these two groups (p=0.20). Postoperative serum IL-6 levels were significantly elevated. Mean serum levels of IL-6 were significantly higher at the end of operation in the transfused group than in the control group (131.7 pg/ml in control group and 269.8 pg/ml in transfused group; p=0.02). Conclusion: The present study suggested that perioperative allogeneic blood transfusion can induce an excessive cytokine response and may be deleterious.
MeSH term(s)	Blood Transfusion ; Colorectal Neoplasms/blood ; Colorectal Neoplasms/surgery ; Enzyme-Linked Immunosorbent Assay ; Humans ; Interleukin-6/blood ; Intraoperative Period ; Postoperative Period ; Transfusion Reaction
Chemical Substances	Interleukin-6
Language	English
Publishing date	1998-07
Publishing country	Greece
Document type	Journal Article
ZDB-ID	801013-4
ISSN	0172-6390
ISSN	0172-6390
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ui V Zs.50: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: [Ras p-21 expression in colorectal neoplasia: preliminary report].

Ishijima, N / Suzuki, H

Nihon Geka Gakkai zasshi

1989 Volume 90, Issue 7, Page(s) 1128

MeSH term(s)	Colorectal Neoplasms/genetics ; Gene Expression ; Genes, ras ; Humans
Language	Japanese
Publishing date	1989-07
Publishing country	Japan
Document type	Journal Article
ZDB-ID	412544-7
ISSN	1880-1129 ; 0301-4894
ISSN (online)	1880-1129
ISSN	0301-4894
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 1737: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito