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  1. Article ; Online: Application of natural preservatives and sweeteners in fruit products to reduce health risks - a review

    Akash Sanjay Valliath / Vishal Johar / Radhajogita Mondal / Swarna Tejaswi / Piu Das / Ishita Saha

    Environment Conservation Journal, Vol 24, Iss

    2023  Volume 4

    Abstract: The costs of food deterioration in terms of both money and health are rising. Fungi, bacteria, yeast, insects, and rodent contamination of food supplies continue to be a major public health concern. Chemical preservatives are effective but can be ... ...

    Abstract The costs of food deterioration in terms of both money and health are rising. Fungi, bacteria, yeast, insects, and rodent contamination of food supplies continue to be a major public health concern. Chemical preservatives are effective but can be potentially fatal to human health in certain cases. As potent food preservatives, essential oils made from plants are a great alternative to synthetic preservatives. They also possess a variety of anti-inflammatory, antibacterial, and antioxidant effects. The use of artificial sweeteners in food products, which raises safety questions and health issues while also having reduced nutritional value, is another problem in the food industry. Because natural sweeteners are linked to a healthy lifestyle and have superior nutritional qualities, consumers today prefer them. This article goes through the issues with artificial sweeteners and preservatives and goes into great length about the many different essential oils and natural sweeteners that are much safer and healthier alternatives.
    Keywords Food spoilage ; Health issues ; Preservative ; Processed food ; Sweetener ; Environmental sciences ; GE1-350
    Subject code 360
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher Action for Sustainable Efficacious Development and Awareness
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Role of anti-Mullerian hormone in polycystic ovary syndrome

    Koushik Bhattacharya / Ishita Saha / Debanjana Sen / Chaitali Bose / Gargi Ray Chaudhuri / Sulagna Dutta / Pallav Sengupta / Soumita Bhattacharya / Sharit Shekhar Barman / Alak Kumar Syamal

    Middle East Fertility Society Journal, Vol 27, Iss 1, Pp 1-

    2022  Volume 10

    Abstract: Abstract Polycystic ovary syndrome (PCOS) is the most common gynecological endocrine disorders affecting up to 10% of all females in their reproductive age, and its cause of onset is still elusive. A spectrum of recent research reflected diverse ... ...

    Abstract Abstract Polycystic ovary syndrome (PCOS) is the most common gynecological endocrine disorders affecting up to 10% of all females in their reproductive age, and its cause of onset is still elusive. A spectrum of recent research reflected diverse associations between increased plasma level of anti-Mullerian hormone (AMH) and different clinical features of PCOS. Since AMH levels reflect the pool of growing follicles that potentially can ovulate, it can be stated that serum AMH levels can be used to assess the “functional ovarian reserve,” rather mentioning it as the “ovarian reserve.” AMH also appears to be a premier endocrine parameter for the assessment of atrophied ovarian follicular pool in response to age of individuals. AMH hinders the follicular development as well as the follicular recruitment and ultimately resulting in follicular arrest which is the key pathophysiologic condition for the onset of PCOS. Furthermore, FSH-induced aromatase activity remains inhibited by AMH that aids emergence of other associated clinical signs of PCOS, such as excess androgen, followed by insulin resistance among the PCOS individuals. Given the versatile association of AMH with PCOS and scarcity in literature explaining the underling mechanisms how AMH relates with PCOS, this review article will discuss the roles of AMH in the pathogenesis of PCOS which may introduce a new era in treatment approach of PCOS.
    Keywords Anti-Mullerian hormone ; Folliculogenesis ; Gonadotropins ; Ovarian reserve ; Polycystic ovary syndrome ; Insulin resistance ; Medicine (General) ; R5-920 ; Reproduction ; QH471-489
    Language English
    Publishing date 2022-10-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Spermine and spermidine act as chemical chaperones and enhance chaperone-like and membranolytic activities of major bovine seminal plasma protein, PDC-109

    Singh, Bhanu Pratap / Indrani Nandi / Ishita Saha / Musti J. Swamy

    Biochemical and biophysical research communications. 2017,

    2017  

    Abstract: The major bovine seminal plasma protein, PDC-109, binds to choline phospholipids of the sperm plasma membrane and induces an efflux of cholesterol and choline phospholipids (cholesterol efflux), which is crucial for sperm capacitation. PDC-109 also ... ...

    Abstract The major bovine seminal plasma protein, PDC-109, binds to choline phospholipids of the sperm plasma membrane and induces an efflux of cholesterol and choline phospholipids (cholesterol efflux), which is crucial for sperm capacitation. PDC-109 also exhibits chaperone-like activity and protects target proteins against various kinds of stress. Here we show that the polyamines spermine and spermidine, present in high concentration in the seminal plasma of various mammals, increase the ability of PDC-109 to perturb membrane structure as well as its chaperone-like activity. Interestingly, spermine/spermidine alone did not perturb membrane structure but exhibited chaperone-like activity by protecting target proteins against thermal and oxidative stress. When spermine/spermidine was used along with PDC-109, the observed chaperone-like activity was considerably higher than that expected for a simple additive effect, suggesting that PDC-109 and the polyamines act in a synergistic fashion. These results indicate that at the high concentrations present in the seminal plasma spermine/spermidine exhibit a positive modulatory effect on the chaperone-like activity of PDC-109 and may also function as chemical chaperones and protect other seminal plasma proteins from various kinds of stress.
    Keywords additive effect ; cattle ; cholesterol ; choline ; molecular chaperones ; oxidative stress ; phospholipids ; plasma membrane ; seminal plasma ; seminal plasma proteins ; sperm capacitation ; spermatozoa ; spermidine ; spermine
    Language English
    Size p. .
    Publishing place Elsevier Inc.
    Document type Article
    Note Pre-press version
    ZDB-ID 205723-2
    ISSN 0006-291X ; 0006-291X
    ISSN (online) 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2017.09.148
    Database NAL-Catalogue (AGRICOLA)

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