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  1. Article ; Online: COVID-19 pandemic: An analysis of the healthcare, social and economic challenges in Bangladesh.

    Islam, Sufia / Islam, Rizwanul / Mannan, Fouzia / Rahman, Sabera / Islam, Tahiya

    Progress in disaster science

    2020  Volume 8, Page(s) 100135

    Abstract: Bangladesh is one of the worst hit countries in South Asia for COVID-19 outbreak. The objective of this article is to analyse healthcare, social and economic challenges faced by the country. Quantitative data and qualitative information from different ... ...

    Abstract Bangladesh is one of the worst hit countries in South Asia for COVID-19 outbreak. The objective of this article is to analyse healthcare, social and economic challenges faced by the country. Quantitative data and qualitative information from different sources have been used. Our analysis indicates that limited well-equipped hospitals, inadequate testing facilities, lack of awareness, improper knowledge, attitude to and practice of rules, poverty and precarious employment are the factors dominant in spreading COVID-19. Strict enforcement measures and ensuring people's adherence to rules may help reduce spread of infections. Adequate healthcare services are essential for establishing proper medical care.
    Language English
    Publishing date 2020-11-17
    Publishing country England
    Document type Journal Article
    ISSN 2590-0617
    ISSN (online) 2590-0617
    DOI 10.1016/j.pdisas.2020.100135
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Clinical features of pneumonia in severely malnourished children with diarrhoea compared to those without diarrhoea.

    Islam, Sufia / Nasrin, Nishat / Tithi, Nigar Sultana / Lehmann, Christian / Chisti, Mohammod Jobayer

    Frontiers in bioscience (Landmark edition)

    2021  Volume 26, Issue 10, Page(s) 717–722

    Abstract: ... ...

    Abstract Introduction
    MeSH term(s) Bangladesh/epidemiology ; Child ; Child, Preschool ; Diarrhea ; Hospitalization ; Humans ; Infant ; Pneumonia/complications ; Retrospective Studies
    Language English
    Publishing date 2021-10-30
    Publishing country Singapore
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2704569-9
    ISSN 2768-6698 ; 1093-9946
    ISSN (online) 2768-6698
    ISSN 1093-9946
    DOI 10.52586/4982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Sensitivity Patterns of Bacterial Pathogens Isolated from Blood Cultures of Under-Five Children with Pneumonia and Clinical Sepsis.

    Islam, Sufia / Akand, Ashiqur Rahman / Nova, Tasnova Tasnim / Lehmann, Christian / Chisti, Mohammod Jobayer

    Life (Basel, Switzerland)

    2021  Volume 11, Issue 5

    Abstract: Treatment options for pneumonia and sepsis by antibiotics are limited due to the development of multidrug-resistant bacterial strains. This unmatched case-control study determined the antibiotic sensitivity against bacterial isolates obtained from septic ...

    Abstract Treatment options for pneumonia and sepsis by antibiotics are limited due to the development of multidrug-resistant bacterial strains. This unmatched case-control study determined the antibiotic sensitivity against bacterial isolates obtained from septic and nonseptic children with pneumonia. Children of either sex aged 0-59 months with a history of cough or shortness of breath and radiologically confirmed pneumonia were enrolled in this study. Cases with clinical signs of sepsis at admission (
    Language English
    Publishing date 2021-05-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life11050450
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: COVID-19 pandemic: An analysis of the healthcare, social and economic challenges in Bangladesh

    Islam, Sufia Islam Rizwanul Mannan Fouzia Rahman Sabera Islam Tahiya

    Progress in Disaster Science

    Abstract: Bangladesh is one of the worst hit countries in South Asia for COVID-19 outbreak The objective of this article is to analyse healthcare, social and economic challenges faced by the country Quantitative data and qualitative information from different ... ...

    Abstract Bangladesh is one of the worst hit countries in South Asia for COVID-19 outbreak The objective of this article is to analyse healthcare, social and economic challenges faced by the country Quantitative data and qualitative information from different sources have been used Our analysis indicates that limited well-equipped hospitals, inadequate testing facilities, lack of awareness, improper knowledge, attitude to and practice of rules, poverty and precarious employment are the factors dominant in spreading COVID-19 Strict enforcement measures and ensuring people's adherence to rules may help reduce spread of infections Adequate healthcare services are essential for establishing proper medical care
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #926481
    Database COVID19

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  5. Article ; Online: COVID-19 pandemic

    Islam, Sufia / Islam, Rizwanul / Mannan, Fouzia / Rahman, Sabera / Islam, Tahiya

    Progress in Disaster Science

    An analysis of the healthcare, social and economic challenges in Bangladesh.

    2020  , Page(s) 100135

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2590-0617
    DOI 10.1016/j.pdisas.2020.100135
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Bacterial Resistance in Pneumonia in Developing Countries-A Role for Iron Chelation.

    Islam, Sufia / Chisti, Mohammod Jobayer / Ahmed, Muniruddin / Anwar, Nafiza / Lehmann, Christian

    Tropical medicine and infectious disease

    2019  Volume 4, Issue 2

    Abstract: Pneumonia represents one of the major infectious diseases in developing countries and is associated with high mortality, in particular in children under the age of five. The main causative bacterial agents ... ...

    Abstract Pneumonia represents one of the major infectious diseases in developing countries and is associated with high mortality, in particular in children under the age of five. The main causative bacterial agents are
    Language English
    Publishing date 2019-04-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2414-6366
    ISSN (online) 2414-6366
    DOI 10.3390/tropicalmed4020059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Endothelial glycocalyx in acute care surgery - what anaesthesiologists need to know for clinical practice.

    Astapenko, David / Benes, Jan / Pouska, Jiri / Lehmann, Christian / Islam, Sufia / Cerny, Vladimir

    BMC anesthesiology

    2019  Volume 19, Issue 1, Page(s) 238

    Abstract: The endothelial glycocalyx (EG) is the thin sugar-based lining on the apical surface of endothelial cells. It has been linked to the physiological functioning of the microcirculation and has been found to be damaged in critical illness and after acute ... ...

    Abstract The endothelial glycocalyx (EG) is the thin sugar-based lining on the apical surface of endothelial cells. It has been linked to the physiological functioning of the microcirculation and has been found to be damaged in critical illness and after acute care surgery. This review aims to describe the role of EG in severely injured patients undergoing surgery, discuss specific situations (e.G. major trauma, hemorrhagic shock, trauma induced coagulopathy) as well as specific interventions commonly applied in these patients (e.g. fluid therapy, transfusion) and specific drugs related to perioperative medicine with regard to their impact on EG.EG in acute care surgery is exposed to damage due to tissue trauma, inflammation, oxidative stress and inadequate fluid therapy. Even though some interventions (transfusion of plasma, human serum albumin, hydrocortisone, sevoflurane) are described as potentially EG protective there is still no specific treatment for EG protection and recovery in clinical medicine.The most important principle to be adopted in routine clinical practice at present is to acknowledge the fragile structure of the EG and avoid further damage which is potentially related to worsened clinical outcome.
    MeSH term(s) Anesthesiology/methods ; Endothelial Cells/metabolism ; Glycocalyx/physiology ; Humans ; Microcirculation/physiology ; Perioperative Care/methods ; Surgical Procedures, Operative/methods
    Language English
    Publishing date 2019-12-20
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ISSN 1471-2253
    ISSN (online) 1471-2253
    DOI 10.1186/s12871-019-0896-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Challenges for microcirculation research in developing countries.

    Islam, Sufia / Ahmed, Najneen / Rivu, Sanzana Fareen / Khalil, Marjana / Tanjia, Nafisa / Lehmann, Christian

    Clinical hemorheology and microcirculation

    2019  Volume 73, Issue 4, Page(s) 599–607

    Abstract: Background: Microvascular dysfunction is a main contributor to morbidity and mortality worldwide. Sophisticated technical tools (e.g. miniaturized hardware, automated software), along with skilled personnel are the prerequisite for quantitative ... ...

    Abstract Background: Microvascular dysfunction is a main contributor to morbidity and mortality worldwide. Sophisticated technical tools (e.g. miniaturized hardware, automated software), along with skilled personnel are the prerequisite for quantitative observations of the microvasculature.
    Objective: This review aimed to get an overview about on-going microcirculatory research in developing countries, particularly of the South-East Asia region for the last five years and to project the challenges faced in microcirculation research in developing countries.
    Methods: Original research articles originating from 194 countries were searched in PubMed database on the field of microcirculation research for the last five years.
    Results: Our findings showed that around 1800 articles have been published from developing countries compared to more than 5000 from developed countries on different aspects of microcirculation. The overall publication per million populations for developing countries was found to be 0.37 where for developed countries it was 3.62.
    Conclusions: Initiation and execution of sophisticated research in microcirculation is a demand of the time. Such research, initially, may seem unmanageable in developing countries with limited resources and infrastructure settings. Collaborative scientific projects may aid in establishing networks for microvascular research in developing countries.
    MeSH term(s) Developing Countries ; Humans ; Microcirculation ; Research Design
    Language English
    Publishing date 2019-06-26
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1381750-4
    ISSN 1875-8622 ; 1386-0291
    ISSN (online) 1875-8622
    ISSN 1386-0291
    DOI 10.3233/CH-190611
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Iron Overload and Breast Cancer: Iron Chelation as a Potential Therapeutic Approach.

    Islam, Sufia / Hoque, Nazia / Nasrin, Nishat / Hossain, Mehnaz / Rizwan, Farhana / Biswas, Kushal / Asaduzzaman, Muhammad / Rahman, Sabera / Hoskin, David W / Sultana, Saki / Lehmann, Christian

    Life (Basel, Switzerland)

    2022  Volume 12, Issue 7

    Abstract: Breast cancer has historically been one of the leading causes of death for women worldwide. As of 2020, breast cancer was reported to have overtaken lung cancer as the most common type of cancer globally, representing an estimated 11.3% of all cancer ... ...

    Abstract Breast cancer has historically been one of the leading causes of death for women worldwide. As of 2020, breast cancer was reported to have overtaken lung cancer as the most common type of cancer globally, representing an estimated 11.3% of all cancer diagnoses. A multidisciplinary approach is taken for the diagnosis and treatment of breast cancer that includes conventional and targeted treatments. However, current therapeutic approaches to treating breast cancer have limitations, necessitating the search for new treatment options. Cancer cells require adequate iron for their continuous and rapid proliferation. Excess iron saturates the iron-binding capacity of transferrin, resulting in non-transferrin-bound iron (NTBI) that can catalyze free-radical reactions and may lead to oxidant-mediated breast carcinogenesis. Moreover, excess iron and the disruption of iron metabolism by local estrogen in the breast leads to the generation of reactive oxygen species (ROS). Therefore, iron concentration reduction using an iron chelator can be a novel therapeutic strategy for countering breast cancer development and progression. This review focuses on the use of iron chelators to deplete iron levels in tumor cells, specifically in the breast, thereby preventing the generation of free radicals. The inhibition of DNA synthesis and promotion of cancer cell apoptosis are the targets of breast cancer treatment, which can be achieved by restricting the iron environment in the body. We hypothesize that the usage of iron chelators has the therapeutic potential to control intracellular iron levels and inhibit the breast tumor growth. In clinical settings, iron chelators can be used to reduce cancer cell growth and thus reduce the morbidity and mortality in breast cancer patients.
    Language English
    Publishing date 2022-06-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life12070963
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: COVID-19 Pandemic: How is Bangladesh coping with the rapid spread of coronavirus infection?

    Islam, Sufia / Mannan, Fouzia / Islam, Tahiya / Rahman, Sabera / Liza, Saki Sultana / Chisti, Mohammod Jobayer / Islam, Rizwanul

    Journal of infection in developing countries

    2020  Volume 14, Issue 10, Page(s) 1098–1105

    Abstract: The novel coronavirus has become a global risk because of its massive transmission and high rates of mutation. Efficient clinical management remains a challenge in combatting the severe acute respiratory syndrome caused by this virulent strain. This ... ...

    Abstract The novel coronavirus has become a global risk because of its massive transmission and high rates of mutation. Efficient clinical management remains a challenge in combatting the severe acute respiratory syndrome caused by this virulent strain. This contagious disease is new to the people of Bangladesh. The country is at high risk of spreading the coronavirus infection particularly because of its high population density. Significant morbidity and mortality have been observed for the quick transmission of this virus since March 8, 2020. The basic objective of this article is to analyze the preparedness of Bangladesh, given its constraints and limitations, to cope with the rapid spread of COVID-19 infection. In doing so, it summarizes the origin of coronavirus, epidemiology, mode of transmission, diagnosis, treatment, prevention and control of the disease. Although many steps have been taken by the Government and the private sector of Bangladesh to create awareness about measures needed to prevent the deadly infections, many people are unaware of and reluctant to accept the prescribed rules. Inadequacy of diagnostic facilities and limitations of clinical care and health care services were major constraints faced in treating COVID-19 infected people in Bangladesh. Greater compliance by the people in following the suggested measures may help reduce the rapid spread of the disease and overcome the challenges faced by this pandemic.
    MeSH term(s) Bangladesh/epidemiology ; Betacoronavirus ; COVID-19 ; Communicable Disease Control/organization & administration ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Guidelines as Topic ; Humans ; Pandemics/prevention & control ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Risk Factors ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-10-31
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2394024-4
    ISSN 1972-2680 ; 2036-6590
    ISSN (online) 1972-2680
    ISSN 2036-6590
    DOI 10.3855/jidc.13289
    Database MEDical Literature Analysis and Retrieval System OnLINE

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