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Article ; Online: Familiarity Factors of Street Features in Pedestrian Wayfindings

Ismail Said

International Journal of Built Environment and Sustainability, Vol 5, Iss

2018 Volume 3

Abstract: From an origin point to a destination point, good wayfinding process requires familiar recognition on the street environment. However, the unclear reasons of identifying street features to determine a route to the destination influences a pedestrian to ... ...

Abstract	From an origin point to a destination point, good wayfinding process requires familiar recognition on the street environment. However, the unclear reasons of identifying street features to determine a route to the destination influences a pedestrian to select the wrong turn, walk in longer distance, and lost his direction. This paper aims to identify the factors that influence pedestrian familiarity, familiar or unfamiliar, in people wayfinding. Two hundred questionnaires were collected in Teluk Intan, Perak, Malaysia. Quotations from 30 interviews were used to triangulate the findings. Factor analysis available in IBM SPSS version 21 was used in exploring the familiarity factors for wayfinding. The finding suggests three factors influenced pedestrian to familiar with the street environment, which the factors are characteristic, attraction, and interest of street features. While, the duplication design of street features, error in defining the position of street features and form similarity of street features influence pedestrian to become unfamiliar with the street environment. This paper implies that thenphysical form of street features gives impact to pedestrian familiarity. Consideration of the three factors that influence pedestrian to familiar with the environment can improve how pedestrian experience in street network especially wayfinding.
Keywords	Affecting factors ; Pedestrian familiarity ; Wayfinding ; Street environment ; Street features ; Architecture ; NA1-9428 ; Human ecology. Anthropogeography ; GF1-900
Subject code	380
Language	English
Publishing date	2018-09-01T00:00:00Z
Publisher	Universiti Teknologi Malaysia
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Mapping the Arab genome.

Mbarek, Hamdi / Ismail, Said I

Nature genetics

2022 Volume 54, Issue 12, Page(s) 1761–1763

MeSH term(s)	Humans ; White People/genetics ; Genome, Human
Language	English
Publishing date	2022-11-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	1108734-1
ISSN	1546-1718 ; 1061-4036
ISSN (online)	1546-1718
ISSN	1061-4036
DOI	10.1038/s41588-022-01239-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A Geo-Spatial Analysis for Characterising Urban Sprawl Patterns in the Batticaloa Municipal Council, Sri Lanka

Mathanraj Seevarethnam / Noradila Rusli / Gabriel Hoh Teck Ling / Ismail Said

Land, Vol 10, Iss 636, p

2021 Volume 636

Abstract: Urban sprawl related to rapid urbanisation in developed and developing nations affects sustainable land use. In Sri Lanka, urban areas have mostly expanded in a rather spontaneous, unplanned manner (based on the current settlers’ subjective movement) ... ...

Abstract	Urban sprawl related to rapid urbanisation in developed and developing nations affects sustainable land use. In Sri Lanka, urban areas have mostly expanded in a rather spontaneous, unplanned manner (based on the current settlers’ subjective movement) rather than conforming to the local government’s development plan. This growth inevitably leads to uncontrolled urban sprawl in many Sri Lankan cities, including Batticaloa. So far, Sri Lanka’s planners or researchers have not yet tackled the sprawling developments in this city. Understanding the different forms and patterns of urban sprawl is the key to address sprawling growth. This study aims to identify the characteristics of urban sprawl in the Batticaloa municipal council using Geographic Information System (GIS) and remote sensing technology. Landsat satellite images for the years 2000, 2010, and 2020 as well as 2002, 2011, and 2019 population data were used and analysed using ArcGIS’ maximum likelihood classification tool and the density function, respectively, to delineate the characteristics of urban sprawl. The results revealed that low-density development, leapfrog development, commercial ribbon development, and scattered growth are the influencing characteristics of urban sprawl in the Batticaloa municipality. These characteristics were found mainly in the urban edge of the city and have led to urban sprawl. The finding provides knowledge into recognising the characteristics of urban sprawl with empirical evidence. It affords a clear direction for future studies of urban sprawl in rapidly growing cities that are numerous in Sri Lanka, and the identified characteristics of urban sprawl can be useful in minimising future sprawl. This result can be a tool for future urban planning and management in the Batticaloa municipality.
Keywords	urban sprawl ; land use ; urbanisation ; leapfrog development ; scattered development ; Agriculture ; S
Subject code	710
Language	English
Publishing date	2021-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Therapeutic aptamers in discovery, preclinical and clinical stages.

Ismail, Said I / Alshaer, Walhan

Advanced drug delivery reviews

2018 Volume 134, Page(s) 51–64

Abstract: The aptamer field witnessed steady growth during the past 28 years as evident from the exponentially increasing number of related publications. The field is "coming of age", but like other biomedical research areas facing a global push towards ... ...

Abstract	The aptamer field witnessed steady growth during the past 28 years as evident from the exponentially increasing number of related publications. The field is "coming of age", but like other biomedical research areas facing a global push towards translational research to carry ideas from bench- to bedside, there is pressure to show impact for aptamers at the clinical end. Being easy-to-make, non-immunogenic, stable and high-affinity nano-ligands, aptamers are perfectly poised to move in this direction. They can specifically bind targets ranging from small molecules to complex multimeric structures, making them potentially useful in a limitless variety of therapeutic approaches. This review will summarize efforts made to accomplish the therapeutic promise of aptamers, with a focus on aptamers directly acting as therapeutic molecules, rather than those used in targeted delivery of other drugs. The review will showcase representative examples at various stages of development, covering different disease categories.
MeSH term(s)	Aptamers, Nucleotide/chemistry ; Aptamers, Nucleotide/therapeutic use ; Drug Discovery ; Humans ; Immune System Diseases/drug therapy ; Inflammation/drug therapy ; Ligands ; Neurodegenerative Diseases/drug therapy
Chemical Substances	Aptamers, Nucleotide ; Ligands
Language	English
Publishing date	2018-08-17
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	639113-8
ISSN	1872-8294 ; 0169-409X
ISSN (online)	1872-8294
ISSN	0169-409X
DOI	10.1016/j.addr.2018.08.006
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Article ; Online: Overcoming Eurocentric bias makes for better science.

Dajani, Rana / Mbarek, Hamdi / Ismail, Said I / Mohammad, Abdullah / Somai, Melek

Med (New York, N.Y.)

2022 Volume 3, Issue 12, Page(s) 813–814

Abstract: To understand disease, scientists are producing comprehensive omics datasets. However, the majority of these are Eurocentric. Recently, the inclusion of patients from Asia and the Middle East in genomic analyses uncovered unique loci linked to COVID-19 ... ...

Abstract	To understand disease, scientists are producing comprehensive omics datasets. However, the majority of these are Eurocentric. Recently, the inclusion of patients from Asia and the Middle East in genomic analyses uncovered unique loci linked to COVID-19 severity. This demonstrates that focusing on diversity and underrepresented populations can benefit all.
Language	English
Publishing date	2022-12-05
Publishing country	United States
Document type	Letter
ISSN	2666-6340
ISSN (online)	2666-6340
DOI	10.1016/j.medj.2022.11.007
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Resilience of Pontian Farmers in the Face of the Impact Changes of Rapid Development in Iskandar Malaysia

Joharudin Samion / Ismail Said / Tun M Irfan Mohd Suria Affandi / Lee Yoke Lai

International Journal of Built Environment and Sustainability, Vol 8, Iss

2021 Volume 2

Abstract: The issues of community resilience arise from the need to develop an understanding of how people would respond to internal and external disturbances. In-depth discussion towards the impact of a city to a neighbouring district has little been discussed. ... ...

Abstract	The issues of community resilience arise from the need to develop an understanding of how people would respond to internal and external disturbances. In-depth discussion towards the impact of a city to a neighbouring district has little been discussed. The District of Pontian is located west of Iskandar Malaysia. It has received an unprecedented level of infrastructural development to boost the economy of Iskandar Malaysia. This study examines the land use pattern change of Pontian District impacted by Iskandar Malaysia. Additionally, the study aims to assess the social, economic and environmental capital and the factors that contribute to the adaptabilities and resilience of farmer communities in Pontian. Build-up area for each period using Google earth satellite imagery from the year 2005 to 2015, was classified to analyze the change of build-up area.Markov Chains technique is appliedto predict changesof land use. Next, survey questionnaires were utilized to measure the levels of community resilience. Subsequently, an interview was employed to identify the factors that contribute to the stresses. The results indicate that rapid development of Iskandar Malaysia gave an impact to agricultural land and changed the land use pattern of Pontian. The findings revealed the perspective of individuals, community, and system resilience capacity to survive. It was found that farmers were able to adapt to various stresses. The result indicates that individuals and communities can be adaptive, absorptive, and transformative. The findings can assist in formulation of strategies for communities to be better prepared for thecurrent and future impactof the triple threat of urbanization, globalization and climate change
Keywords	community resilience ; iskandar malaysia ; farmer community ; Architecture ; NA1-9428 ; Human ecology. Anthropogeography ; GF1-900
Subject code	710
Language	English
Publishing date	2021-05-01T00:00:00Z
Publisher	Universiti Teknologi Malaysia
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: SARS-CoV-2 entry in host cells-multiple targets for treatment and prevention.

Mahmoud, Ismail Sami / Jarrar, Yazun Bashir / Alshaer, Walhan / Ismail, Said

Biochimie

2020 Volume 175, Page(s) 93–98

Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new viral disease that has gained global attention owing to its ability to provoke community and health-care-associated outbreaks of severe infections in human populations. The virus poses ...

Abstract	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new viral disease that has gained global attention owing to its ability to provoke community and health-care-associated outbreaks of severe infections in human populations. The virus poses serious challenges to clinical management because there are still no approved anti- SARS-CoV-2 drugs available. In this mini-review, we summarize the much updated published reports that demonstrate the mechanism of SARS-CoV-2 entry into host cells, and discuss the availability and development of attractive host-based therapeutic options for SARS-CoV-2 infections.
MeSH term(s)	Betacoronavirus/metabolism ; Betacoronavirus/pathogenicity ; COVID-19 ; Coronavirus Infections/metabolism ; Coronavirus Infections/therapy ; Host-Pathogen Interactions/physiology ; Humans ; Pandemics ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/therapy ; SARS-CoV-2 ; Virus Internalization
Keywords	covid19
Language	English
Publishing date	2020-05-29
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	120345-9
ISSN	1638-6183 ; 0300-9084
ISSN (online)	1638-6183
ISSN	0300-9084
DOI	10.1016/j.biochi.2020.05.012
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Article ; Online: Differences of Street Connectivity Between Old And New Zones In Malaysian Small Town

Ismail Said / Wan Saiful Nizam Wan Mohamad

International Journal on Advanced Science, Engineering and Information Technology, Vol 7, Iss 4, Pp 1464-

2017 Volume 1470

Abstract: From the period before Malaysia’s independence until now, there are two significant characteristics of the town formed in small town. Pedestrian behavior in the streets is affected by the connectivity existed from the pattern of the street network of a ... ...

Abstract	From the period before Malaysia’s independence until now, there are two significant characteristics of the town formed in small town. Pedestrian behavior in the streets is affected by the connectivity existed from the pattern of the street network of a town. Thus, the existing of characteristics of new and old zone require pedestrian to travel differently in those environments. By considering a small town consists of the old and new zone and population between 30,000 to 100,000, street network of Bandar Teluk Intan, Perak was selected. Three sets of data were produced from the land use map and Google Map image, then analyzed it using UCL Depthmap 10. Firstly, solid and void data was used in Visibility graph analysis to measure street connectivity from pedestrian visualization. Second data which convex space data used in Convex space graph analysis to measure street connectivity of spaces in street network that offer pedestrian interaction. Axial-line data is the third data was used in Axial-line graph analysis to measure street connectivity from pedestrian movement in street network. Finding shows that in old zone, junctions act as a connector to other streets when pedestrian visualize during travel, space in square and market chosen as meeting place, and main road as a guide when pedestrian move. In new zone, main road is a connecting feature for pedestrian because it's easy to find, connect with most streets, and the possible space to meet people during travel.
Keywords	Street Network ; Street Connectivity ; Visibility Analysis ; Convex Space Analysis ; Axial-Line Analysis ; Science (General) ; Q1-390 ; Science ; Q
Subject code	380
Language	English
Publishing date	2017-08-01T00:00:00Z
Publisher	Indonesian Society for Knowledge and Human Development (INSIGHT)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Adolescents’ Sense of Community and Involvement in Playground Activities

Oluwagbemiga Paul Agboola / Mohamad Hisyam Rasidi / Ismail Said

International Journal of Built Environment and Sustainability, Vol 4, Iss

Panacea to Ameliorate Social Vices and Delinquencies

2017 Volume 2

Abstract: Researchers have identified defects in the physical environments in which they interact and play, which has resulted in a decline the expected values initiated in both the social, physical and psychological developments. The role of playground in the ... ...

Abstract	Researchers have identified defects in the physical environments in which they interact and play, which has resulted in a decline the expected values initiated in both the social, physical and psychological developments. The role of playground in the development of adolescent’s health, moral and social standard has attracted lower interest in the recent time. The adolescent sense of community relates to a positive experience in the community open space setting such as playground and social well-being with their peers in general. Over time, little efforts have been initiated by the researchers towards these phenomena. This current study fills the gap by examining the adolescents’ sense of community through a quantitative survey via appraisal of the quality of community playground, emotional connection and effects of their participation in playground activities on ameliorating the delinquents’ behavior and social vices. Completed survey questionnaires retrieved from a total number of 69 purposive respondents who are adolescents from three towns and analyzed through relative importance index (RII) via Likert scale. Results from the analysis indicated that adolescents’ positive attitudinal changes and reduction in social vices and delinquent’s behavior could be achieved through their involvements in quality and well-equipped playgrounds. Similarly, the significant role of sense of community in enhancing adolescent social participation in playground activities contributes to a major role in increasing their social well-being and togetherness. Thus, the study recommends appropriate future planning, design, and management of neighborhood playgrounds in Nigeria.
Keywords	Architecture ; NA1-9428 ; Human ecology. Anthropogeography ; GF1-900
Subject code	300
Language	English
Publishing date	2017-05-01T00:00:00Z
Publisher	Universiti Teknologi Malaysia
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: From goodwill to good deals: FELDA land resettlement scheme and the ascendancy of the landless poor in Malaysia

Barau, Aliyu Salisu / Ismail Said

Land use policy. 2016 July, v. 54

2016

Abstract: Land resettlement schemes are commonly used in the developing countries to leverage poor people’s access to land for shelter, food production, or boosting rural development. Unfortunately, not many resettlement schemes have effectively solved the ... ...

Abstract	Land resettlement schemes are commonly used in the developing countries to leverage poor people’s access to land for shelter, food production, or boosting rural development. Unfortunately, not many resettlement schemes have effectively solved the problems they were designed to tackle. For researchers and policymakers in particular, part of the problem has been the lack of enabling analytical tools for holistic and an in-depth analysis of the trajectories of the few successful models of land resettlement schemes. The current study examines the features of one of the most successful land resettlement initiatives, namely the Federal Land Development Authority (FELDA) scheme in Malaysia. Established in 1956, the scheme comprises over 400 settler communities that cover about 16% of Malaysia’s total land area. The FELDA scheme has tremendously transformed the lives of the landless population through provision of shelter, jobs, income from agribusiness shareholding, and ownership of highly valorised land titles. This study combined the path dependency approach and Earth system governance analytic tools to examine the trajectories and multidimensional features that make the FELDA scheme a good example to reckon with. Thus, broadening researchers and policymakers appreciation of the role of analytical dimensions is a major contribution of this study to the current debates on the pro-poor land governance strategies in the Global South. Finally, the study shines some light at the role of land governance in streamlining land development and goals of sustainable national planning.
Keywords	agribusiness ; developing countries ; Earth system science ; employment ; food production ; governance ; income ; land use ; models ; national planning ; ownership ; rural development ; Malaysia
Language	English
Dates of publication	2016-07
Size	p. 423-431.
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	852476-2
ISSN	0264-8377
ISSN	0264-8377
DOI	10.1016/j.landusepol.2016.03.009
Database	NAL-Catalogue (AGRICOLA)

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