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  1. Article ; Online: RETRACTED: Neurocutaneous Melanosis and Nevus of Ota: A Brief Report.

    Issa, Chad P / Issa, Peter P / Allen, Whitney / Pollard, Hayden / Bouquet, Mikki

    publication RETRACTED

    Clinical pediatrics

    2023  Volume 63, Issue 4, Page(s) NP1–NP4

    Language English
    Publishing date 2023-04-20
    Publishing country United States
    Document type Journal Article ; Retracted Publication
    ZDB-ID 207678-0
    ISSN 1938-2707 ; 0009-9228
    ISSN (online) 1938-2707
    ISSN 0009-9228
    DOI 10.1177/00099228231165713
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Hashimoto's Thyroiditis: A Protective Factor against Recurrence in BRAF-Wild Type Differentiated Thyroid Carcinoma.

    Issa, Peter P / Omar, Mahmoud / Buti, Yusef / Aboueisha, Mohamed / Munshi, Ruhul / Hussein, Mohammad / Haidari, Muhib / Blair, Graham / Issa, Chad P / Shama, Mohamed / Toraih, Eman / Kandil, Emad

    Cancers

    2023  Volume 15, Issue 8

    Abstract: A recent work analyzing the concomitant factors BRAF mutation (risk factor) and Hashimoto's thyroiditis (HT) (protective factor) found that the presence of HT reduced lymph node metastasis in BRAF-mutated papillary thyroid carcinoma. Whether this notion ... ...

    Abstract A recent work analyzing the concomitant factors BRAF mutation (risk factor) and Hashimoto's thyroiditis (HT) (protective factor) found that the presence of HT reduced lymph node metastasis in BRAF-mutated papillary thyroid carcinoma. Whether this notion is upheld with respect to disease recurrence and differentiated thyroid carcinoma (DTC), however, is unknown. We aimed to investigate the effect of underlying HT in DTC patients and its influence on recurrence with a specific emphasis in BRAF-mutated tumors. A total of 469 patients were included. Patients were stratified according to BRAF and HT status. Multivariate regression analysis was conducted to determine protective and risk factors of disease recurrence in patients with DTC. HT was associated with less-aggressive carcinomas including more frequent microcarcinomas (HT: 45.0% vs. no-HT: 34.0%,
    Language English
    Publishing date 2023-04-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15082371
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: From ablation to operation: Unraveling the surgical outcomes and complications of thyroidectomy after radiofrequency ablation.

    Hussein, Mohammad / Toraih, Eman / Issa, Peter P / Omar, Mahmoud / Aboueisha, Mohamed / Buti, Yusef / Issa, Chad P / Albuck, Aaron L / Cironi, Katherine / Attia, Abdallah S / LaForteza, Alexandra C / Shama, Mohamed / Kandil, Emad

    Surgery

    2023  Volume 175, Issue 1, Page(s) 146–152

    Abstract: Background: Radiofrequency ablation is a minimally invasive treatment for thyroid nodules; however, concerns exist regarding its impact on subsequent thyroid surgery. We compared surgical outcomes and complications between patients undergoing ... ...

    Abstract Background: Radiofrequency ablation is a minimally invasive treatment for thyroid nodules; however, concerns exist regarding its impact on subsequent thyroid surgery. We compared surgical outcomes and complications between patients undergoing thyroidectomy after radiofrequency ablation (post-radiofrequency ablation thyroidectomy group) and those without prior radiofrequency ablation (non-radiofrequency ablation thyroidectomy group).
    Methods: We retrospectively analyzed thyroidectomy patients, comparing post-radiofrequency ablation thyroidectomy and non-radiofrequency ablation thyroidectomy groups, examining demographics, nodule characteristics, surgical techniques, and complications.
    Results: The study included 96 patients (73 in the non-radiofrequency ablation thyroidectomy group and 23 in the post-radiofrequency ablation thyroidectomy group). The mean age was 53.3 ± 14.4 years, with 78.1% female patients and 36.5% African American patients. Median operative time was similar between the post-radiofrequency ablation thyroidectomy (110 minutes) and the non-radiofrequency ablation thyroidectomy (92 minutes) cohorts (P = .40). Complications were reported in 13 patients, without significant differences between groups (P = .54). No permanent complications, including nerve injury or hypoparathyroidism, were reported in either cohort. Prior radiofrequency ablation treatment did not increase the risk of complications (odds ratio = 3.48, 95% confidence interval = 0.70-17.43, P = .16).
    Conclusion: Our work found no differences in outcomes or safety in patients undergoing thyroidectomy with or without previous radiofrequency ablation treatment, potentiating the post-radiofrequency ablation thyroidectomy group as a safe management option. Accordingly, this may reassure both clinicians and patients of the safety of radiofrequency ablation in treating patients with thyroid nodules.
    MeSH term(s) Humans ; Female ; Adult ; Middle Aged ; Aged ; Male ; Thyroidectomy/adverse effects ; Thyroidectomy/methods ; Thyroid Nodule/surgery ; Retrospective Studies ; Radiofrequency Ablation/adverse effects ; Treatment Outcome ; Catheter Ablation/adverse effects ; Catheter Ablation/methods
    Language English
    Publishing date 2023-10-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 202467-6
    ISSN 1532-7361 ; 0039-6060
    ISSN (online) 1532-7361
    ISSN 0039-6060
    DOI 10.1016/j.surg.2023.09.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Radiofrequency Ablation of Indeterminate Thyroid Nodules: The First North American Comparative Analysis.

    Issa, Peter P / Omar, Mahmoud / Issa, Chad P / Buti, Yusef / Hussein, Mohammad / Aboueisha, Mohamed / Abdelhady, Ali / Shama, Mohamed / Lee, Grace S / Toraih, Eman / Kandil, Emad

    International journal of molecular sciences

    2022  Volume 23, Issue 19

    Abstract: Thyroid nodules can be classified as benign, malignant, or indeterminate, the latter of which make up 10-30% of nodules. Radiofrequency ablation (RFA) has become an attractive and promising therapy for the treatment of benign thyroid nodules. However, ... ...

    Abstract Thyroid nodules can be classified as benign, malignant, or indeterminate, the latter of which make up 10-30% of nodules. Radiofrequency ablation (RFA) has become an attractive and promising therapy for the treatment of benign thyroid nodules. However, few studies have investigated the safety and efficacy of RFA for the management of indeterminate thyroid nodules. In this study, 178 patients with thyroid nodules diagnosed as benign (Bethesda II) or indeterminate (Bethesda III/IV) by preoperative cytopathological analysis were included. Patients in the benign and indeterminate cohorts had similar thyroid nodule volume reduction rates at 65.60% and 64.20%, respectively (
    MeSH term(s) Catheter Ablation/adverse effects ; Humans ; North America ; Radiofrequency Ablation ; Retrospective Studies ; Thyroid Nodule/diagnosis ; Treatment Outcome
    Language English
    Publishing date 2022-09-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms231911493
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Hashimoto's Thyroiditis Minimizes Lymph Node Metastasis in

    Issa, Peter P / Omar, Mahmoud / Buti, Yusef / Issa, Chad P / Chabot, Bert / Carnabatu, Christopher J / Munshi, Ruhul / Hussein, Mohammad / Aboueisha, Mohamed / Shama, Mohamed / Corsetti, Ralph L / Toraih, Eman / Kandil, Emad

    Biomedicines

    2022  Volume 10, Issue 8

    Abstract: Hashimoto's thyroiditis (HT) (autoimmune thyroiditis) is a clinicopathological entity associated with chronic lymphocytic infiltration resulting in hypothyroidism. HT is a double-edged sword that increases the risk of papillary thyroid cancer (PTC), yet ... ...

    Abstract Hashimoto's thyroiditis (HT) (autoimmune thyroiditis) is a clinicopathological entity associated with chronic lymphocytic infiltration resulting in hypothyroidism. HT is a double-edged sword that increases the risk of papillary thyroid cancer (PTC), yet it serves as a protective factor for PTC progression.
    Language English
    Publishing date 2022-08-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines10082051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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