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  1. Article: [Current Status and Challenges of Cancer Survivorship Researchs in Japan].

    Ito, Yuri

    Gan to kagaku ryoho. Cancer & chemotherapy

    2024  Volume 51, Issue 2, Page(s) 115–118

    Abstract: Cancer patients have been able to live longer according to the development of early diagnosis and treatment. On the other hand, prolonged treatment period, increased cost burdens, and various late complications can occur as a result. In this article, I ... ...

    Abstract Cancer patients have been able to live longer according to the development of early diagnosis and treatment. On the other hand, prolonged treatment period, increased cost burdens, and various late complications can occur as a result. In this article, I introduce research on cancer survivorship in Japan, about the statistics for cancer survivors, physical, mental, and social late complications. I also summarize the issues of survivorship research that should be conducted in Japan in the future. First, the 5-year survival has been used as a prognostic indicator for cancer survivors, however, the conditional survival, which is more useful information to predict the patients' future, was introduced. In addition, studies on late complications of cancer patients were summarized, including studies on the development of secondary cancer as a physical complication, suicide as a psychological complication, and continued employment and economic toxicity as social complications. Finally, we summarized the research and data bases that are needed to realize"cancer control that leaves no one behind".
    MeSH term(s) Humans ; Japan ; Cancer Survivors ; Databases, Factual ; Employment ; Neoplasms, Second Primary
    Language Japanese
    Publishing date 2024-03-07
    Publishing country Japan
    Document type English Abstract ; Journal Article
    ZDB-ID 604842-0
    ISSN 0385-0684
    ISSN 0385-0684
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2573: Show issues Location:
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  2. Article ; Online: Who should be treated for nontuberculous mycobacterial pulmonary disease?

    Ito, Yutaka

    Respiratory investigation

    2023  Volume 61, Issue 4, Page(s) 387–388

    MeSH term(s) Humans ; Mycobacterium Infections, Nontuberculous/drug therapy ; Mycobacterium Infections, Nontuberculous/microbiology ; Lung Diseases/therapy
    Language English
    Publishing date 2023-04-19
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2660821-2
    ISSN 2212-5353 ; 2212-5345
    ISSN (online) 2212-5353
    ISSN 2212-5345
    DOI 10.1016/j.resinv.2023.03.002
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  3. Article ; Online: Hidetoshi Yamada: His journey in the carbohydrate world.

    Ito, Yukishige

    Advances in carbohydrate chemistry and biochemistry

    2022  Volume 81, Page(s) 3–7

    Abstract: Professor Hidetoshi Yamada, who demonstrated his creativity in various respects, passed away in November 2019. His research targets were highly diverse, including sweet saponins, ellagitannins, novel cyclodextrins, and conformationally distorted donors ... ...

    Abstract Professor Hidetoshi Yamada, who demonstrated his creativity in various respects, passed away in November 2019. His research targets were highly diverse, including sweet saponins, ellagitannins, novel cyclodextrins, and conformationally distorted donors for stereoselective glycosylations. In memory of his creativity, this chapter highlights his prominent achievements in carbohydrate chemistry.
    MeSH term(s) Humans ; Candy ; Chemistry, Organic ; Cyclodextrins ; Educational Personnel ; Glycosylation
    Chemical Substances Cyclodextrins
    Language English
    Publishing date 2022-10-28
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2162-5530
    ISSN (online) 2162-5530
    DOI 10.1016/bs.accb.2022.09.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online: HOKEM

    Ito, Yoshiki

    Human and Object Keypoint-based Extension Module for Human-Object Interaction Detection

    2023  

    Abstract: Human-object interaction (HOI) detection for capturing relationships between humans and objects is an important task in the semantic understanding of images. When processing human and object keypoints extracted from an image using a graph convolutional ... ...

    Abstract Human-object interaction (HOI) detection for capturing relationships between humans and objects is an important task in the semantic understanding of images. When processing human and object keypoints extracted from an image using a graph convolutional network (GCN) to detect HOI, it is crucial to extract appropriate object keypoints regardless of the object type and to design a GCN that accurately captures the spatial relationships between keypoints. This paper presents the human and object keypoint-based extension module (HOKEM) as an easy-to-use extension module to improve the accuracy of the conventional detection models. The proposed object keypoint extraction method is simple yet accurately represents the shapes of various objects. Moreover, the proposed human-object adaptive GCN (HO-AGCN), which introduces adaptive graph optimization and attention mechanism, accurately captures the spatial relationships between keypoints. Experiments using the HOI dataset, V-COCO, showed that HOKEM boosted the accuracy of an appearance-based model by a large margin.

    Comment: Accepted to IEEE ICIP 2023
    Keywords Computer Science - Computer Vision and Pattern Recognition ; Computer Science - Machine Learning
    Subject code 004
    Publishing date 2023-06-25
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Increased data accumulation from COVID-19 cases in children is needed.

    Ito, Yoshinori

    Pediatrics international : official journal of the Japan Pediatric Society

    2021  Volume 63, Issue 9, Page(s) 1006

    MeSH term(s) COVID-19 ; Child ; Humans ; SARS-CoV-2
    Language English
    Publishing date 2021-09-02
    Publishing country Australia
    Document type Editorial ; Comment
    ZDB-ID 1470376-2
    ISSN 1442-200X ; 1328-8067
    ISSN (online) 1442-200X
    ISSN 1328-8067
    DOI 10.1111/ped.14711
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 848: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Comparison of visual outcomes between medical treatment alone and Ahmed glaucoma valve implantation in Shiba dogs with primary angle closure glaucoma.

    Kubo, Akira / Ito, Yosuke

    Veterinary ophthalmology

    2024  

    Abstract: Objective: The objective of the study was to evaluate visual outcomes between medical treatment alone (MED) and Ahmed glaucoma valve implantation (AGVI) in Shiba dogs with primary angle closure glaucoma (PACG).: Procedures: Records of 65 Shiba dogs ( ... ...

    Abstract Objective: The objective of the study was to evaluate visual outcomes between medical treatment alone (MED) and Ahmed glaucoma valve implantation (AGVI) in Shiba dogs with primary angle closure glaucoma (PACG).
    Procedures: Records of 65 Shiba dogs (104 eyes) with PACG were retrospectively reviewed. Vision was assessed qualitatively using both the menace response and maze testing. The significance of age, sex, intraocular pressure (IOP), and duration of clinical signs (≤72 h or >72 h) at first presentation (V1) was assessed. Eyes with vision at V1 were divided into groups according to subsequent treatment method (MED versus AGVI), and vision as a survival outcome was compared between group by the Kaplan-Meier method.
    Results: At V1, 65 eyes (62.5%) of 54 dogs had vision. There was no statistically significant difference in age or sex on the presence of vision at V1. Median IOP was higher in blind (52 mmHg) compared to sighted eyes (28 mmHg) (p < .001). Eyes presenting in ≤72 h of the onset of clinical signs were more likely to have vision (86.7%) compared to those presenting after 72 h (44.1%) (p < .001). By the Kaplan-Meier analysis, the cumulative visual retention rate was significantly higher with AGVI than with MED (69.2% vs. 7.7%; p < .01) at 12 months. The median time to visual loss was 39.9 months with AGVI vs. 1.7 months with MED.
    Conclusions: AGVI resulted in better visual outcomes than MED and should be considered in Shiba dogs with PACG that are visual at the time of presentation and suitable for surgery.
    Language English
    Publishing date 2024-02-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2011043-1
    ISSN 1463-5224 ; 1463-5216
    ISSN (online) 1463-5224
    ISSN 1463-5216
    DOI 10.1111/vop.13189
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  7. Article ; Online: The contribution of carbon budget to masting intervals in Veratrum album populations inhabiting different elevations.

    Ito, Yohei / Kudo, Gaku

    American journal of botany

    2024  Volume 111, Issue 3, Page(s) e16295

    Abstract: Premise: Mast flowering/seeding is often more extreme in lower-resource environments, such as alpine compared to lowland habitats. We studied a masting herb that had less extreme masting at higher elevations, and tested if this difference could be ... ...

    Abstract Premise: Mast flowering/seeding is often more extreme in lower-resource environments, such as alpine compared to lowland habitats. We studied a masting herb that had less extreme masting at higher elevations, and tested if this difference could be explained by higher photosynthetic productivity and/or lower reproductive investment at the higher-elevation sites.
    Methods: We examined the relationship between flowering intervals and carbon budget (i.e., the balance between reproductive investment and annual carbon fixation) in a masting herb, Veratrum album subsp. oxysepalum, across five lowland and six alpine populations in northern Japan. We evaluated the previous flowering histories of individual plants based on rhizome morphology and analyzed the masting patterns of individual populations. Total mass of the reproductive organs, as a proxy of reproductive investment, was compared between the lowland and alpine populations. Annual carbon fixation was estimated on the basis of photosynthetic capacity, total leaf area per plant, and seasonal transition of light availability.
    Results: Interval between high-flowering years was shorter and total reproductive investment was smaller in the alpine than in the lowland populations. Owing to its high photosynthetic capacity and continuous bright conditions, annual carbon fixation per plant was 1.5 times greater in alpine habitat than in lowland habitat. These results suggest that V. album alpine populations have shorter flowering intervals than lowland populations due to faster recovery from energy loss after reproduction.
    Conclusions: Our study demonstrated that masting intervals in V. album populations can be explained by habitat-specific carbon budget balances.
    MeSH term(s) Veratrum ; Carbon ; Reproduction ; Rhizome ; Photosynthesis ; Seeds
    Chemical Substances Carbon (7440-44-0)
    Language English
    Publishing date 2024-02-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2935-x
    ISSN 1537-2197 ; 0002-9122
    ISSN (online) 1537-2197
    ISSN 0002-9122
    DOI 10.1002/ajb2.16295
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  8. Article ; Online: Covalently immobilized biosignal molecule materials for tissue engineering.

    Ito, Yoshihiro

    Soft matter

    2020  Volume 4, Issue 1, Page(s) 46–56

    Abstract: Immobilization of biosignal molecules including growth factors and cytokines is important for developing biologically active materials which can contribute to tissue engineering as a component. The immobilization has more meanings than only ... ...

    Abstract Immobilization of biosignal molecules including growth factors and cytokines is important for developing biologically active materials which can contribute to tissue engineering as a component. The immobilization has more meanings than only immobilization of the enzyme in a bioreactor or ligand-receptor interactions, because the immobilized biosignal molecules work on cells which have very complex structures and functions. This review discusses recent progress in immobilization of biosignal molecules, including the mechanisms and design concepts.
    Language English
    Publishing date 2020-09-07
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2191476-X
    ISSN 1744-6848 ; 1744-683X
    ISSN (online) 1744-6848
    ISSN 1744-683X
    DOI 10.1039/b708359a
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  9. Article: [Socioeconomic Inequalities in Cancer Outcome in Japan].

    Ito, Yuri

    Gan to kagaku ryoho. Cancer & chemotherapy

    2020  Volume 47, Issue 7, Page(s) 1007–1011

    Abstract: The Japanese government set the target to "reduce health inequalities" in the second version of "Healthy Japan 21". However, it is not enough to monitor the socioeconomic inequalities in cancer. In England, National Health Service(NHS) targeted to " ... ...

    Abstract The Japanese government set the target to "reduce health inequalities" in the second version of "Healthy Japan 21". However, it is not enough to monitor the socioeconomic inequalities in cancer. In England, National Health Service(NHS) targeted to "tackle the inequalities in cancer" since 2000. In this review, I introduced some researches for the socioeconomic inequalities in cancer in Japan. We monitored the area-level socioeconomic inequalities in mortality using vital statistics data in Japan using the areal-based deprivation index. Among total inequalities in all cause of death, inequalities in cancer death is the most contributed. Inequalities in lung cancer mortality were widest for both sexes, which is related to the inequalities in smoking rate. We also monitored socioeconomic inequalities in stage-specific incidence using population-based cancer registry. For most of cancer sites, higher late-stage incidence were observed in the more deprived area, which might be due to poor access to the cancer screening in those area. Socioeconomic inequalities in cancer survival were also observed, especially for the cancer sites which has favor prognosis. Although stage at diagnosis plays an important role in these socioeconomic inequalities, other factors such as co-morbidities are likely play a part. We need further study to understand the mechanism of inequalities in cancer using more clinically detail database in near future.
    MeSH term(s) Female ; Humans ; Incidence ; Japan ; Male ; Neoplasms/economics ; Neoplasms/therapy ; Sex Factors ; Socioeconomic Factors ; State Medicine
    Language Japanese
    Publishing date 2020-06-18
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 604842-0
    ISSN 0385-0684
    ISSN 0385-0684
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Active Surveillance May Be the Best Initial Management for Papillary Thyroid Microcarcinoma.

    Ito, Yasuhiro / Miyauchi, Akira

    Journal of the Endocrine Society

    2023  Volume 7, Issue 7, Page(s) bvad063

    Abstract: Active surveillance for low-risk papillary thyroid microcarcinoma (PTMC; T1aN0MI) was initiated at Kuma Hospital (Kobe, Japan) in 1993, based on a proposal by Akira Miyauchi. Favorable outcomes of such surveillance have been reported. Our latest study ... ...

    Abstract Active surveillance for low-risk papillary thyroid microcarcinoma (PTMC; T1aN0MI) was initiated at Kuma Hospital (Kobe, Japan) in 1993, based on a proposal by Akira Miyauchi. Favorable outcomes of such surveillance have been reported. Our latest study revealed 5- and 10-year tumor enlargement rates (by ≥ 3 mm) of 3.0% and 5.5% and 5- and 10-year node metastasis appearance rates of 0.9% and 1.1%, respectively. The postoperative prognosis did not differ between patients who underwent immediate surgery and those who underwent conversion surgery after progression. These findings suggest that active surveillance may be the best initial management of PTMCs.
    Language English
    Publishing date 2023-05-16
    Publishing country United States
    Document type Journal Article
    ISSN 2472-1972
    ISSN (online) 2472-1972
    DOI 10.1210/jendso/bvad063
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