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  1. Article ; Online: Testing entanglement of annihilation photons.

    Ivashkin, Alexander / Abdurashitov, Dzhonrid / Baranov, Alexander / Guber, Fedor / Morozov, Sergey / Musin, Sultan / Strizhak, Alexander / Tkachev, Igor

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 7559

    Abstract: We present a new experimental study of the quantum entanglement of photon pairs produced in positron-electron annihilation at rest. Each annihilation photon has an energy that is five orders of magnitude higher than the energy of photons in optical ... ...

    Abstract We present a new experimental study of the quantum entanglement of photon pairs produced in positron-electron annihilation at rest. Each annihilation photon has an energy that is five orders of magnitude higher than the energy of photons in optical experiments. It provides a unique opportunity for controlled Compton pre-scattering of initial photons before the polarization measurements. The experimental setup includes a system of Compton polarimeters to measure the angular correlations of annihilation photons in initial and thus prepared pre-scattered states. For the first time, a direct comparison of the polarization correlations of initial and pre-scattered annihilation photons has been carried out. The angular distributions of scattered in polarimeters photons turned out to be the same for both types of events. Moreover, the correlation function in the Bell's inequality is also the same for both states. We discuss the implications of our results for quantum measurement theory and for the quantum-entangled positron emission tomography.
    Language English
    Publishing date 2023-05-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-34767-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Mesenchymal Cells Retain the Specificity of Embryonal Origin During Osteogenic Differentiation.

    Lobov, Arseniy / Kuchur, Polina / Khizhina, Aigul / Kotova, Anastasia / Ivashkin, Andrei / Kostina, Daria / Klausen, Polina / Khokhlova, Evgeniia / Repkin, Egor / Postnikova, Kseniia / Perepletchikova, Daria / Denisov, Evgeny / Gerashchenko, Tatiana / Tikhilov, Rashid / Bozhkova, Svetlana / Sereda, Andrey / Karelkin, Vitaliy / Enukashvily, Natella / Malashicheva, Anna

    Stem cells (Dayton, Ohio)

    2023  Volume 42, Issue 1, Page(s) 76–89

    Abstract: Mesenchymal stem cells (MSCs) are widely used in therapy, but the differences between MSCs of various origins and their ability to undergo osteogenic differentiation and produce extracellular matrix are not fully understood. To address this, we conducted ...

    Abstract Mesenchymal stem cells (MSCs) are widely used in therapy, but the differences between MSCs of various origins and their ability to undergo osteogenic differentiation and produce extracellular matrix are not fully understood. To address this, we conducted a comparative analysis of mesenchymal cell primary cultures from 6 human sources, including osteoblast-like cells from the adult femur, adipose-derived stem cells, Wharton's jelly-derived mesenchymal cells, gingival fibroblasts, dental pulp stem cells, and periodontal ligament stem cells. We analyzed these cells' secretome, proteome, and transcriptome under standard and osteogenic cultivation conditions. Despite the overall similarity in osteogenic differentiation, the cells maintain their embryonic specificity after isolation and differentiation in vitro. Furthermore, we propose classifying mesenchymal cells into 3 groups: dental stem cells of neural crest origin, mesenchymal stem cells, and fetal stem cells. Specifically, fetal stem cells have the most promising secretome for various applications, while mesenchymal stem cells have a specialized secretome optimal for extracellular matrix production. Nevertheless, mesenchymal cells from all sources secreted core bone extracellular matrix-associated proteins. In conclusion, our study illuminates the distinctive characteristics of mesenchymal stem cells from various sources, providing insights into their potential applications in regenerative medicine and enhancing our understanding of the inherent diversity of mesenchymal cells in vivo.
    MeSH term(s) Adult ; Humans ; Osteogenesis ; Wharton Jelly ; Cell Differentiation ; Cell Culture Techniques ; Cells, Cultured ; Mesenchymal Stem Cells/metabolism
    Language English
    Publishing date 2023-11-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1143556-2
    ISSN 1549-4918 ; 1066-5099
    ISSN (online) 1549-4918
    ISSN 1066-5099
    DOI 10.1093/stmcls/sxad081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [External osteosynthesis according to G.A. Ilizarov in the treatment of lesions of the distal tibia].

    Khrupkin, V I / Artem'ev, A A / Ivashkin, A N / Maksimenko, V N / Varenik, N N

    Voenno-meditsinskii zhurnal

    2007  Volume 328, Issue 4, Page(s) 46–52

    MeSH term(s) External Fixators ; Fracture Healing ; Humans ; Ilizarov Technique/instrumentation ; Recovery of Function ; Tibial Fractures/surgery ; Trauma Severity Indices ; Treatment Outcome
    Language Russian
    Publishing date 2007-04
    Publishing country Russia (Federation)
    Document type Clinical Trial ; Journal Article
    ZDB-ID 392041-0
    ISSN 0026-9050 ; 0300-9114
    ISSN 0026-9050 ; 0300-9114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Rol' EGF-stimulirovannogo épidermisa v reguliatsii zazhivleniia ran.

    Ivanov, A A / Fedorov, D N / Vasil'ev, A V / Khodzhabekian, G V / Ivashkin, A N

    Arkhiv patologii

    2002  Volume 64, Issue 1, Page(s) 11–14

    Abstract: Sluggish wounds are characterized by impaired proportions of proinflammatory cytokines, deficiency of fibrogenic growth factors, imbalance in the system of matrix metalloproteinases and their inhibitors this preventing reparation. The study was made of ... ...

    Title translation The role of EGF-stimulated epidermis in the regulation of wound healing.
    Abstract Sluggish wounds are characterized by impaired proportions of proinflammatory cytokines, deficiency of fibrogenic growth factors, imbalance in the system of matrix metalloproteinases and their inhibitors this preventing reparation. The study was made of biopsies obtained from patients with sluggish wounds before the treatment, 5, 10 and 15 days after transplantation on the wound of allogenic EGF-stimulated cryopreserved epidermis. The wound closure with biologically active coat was followed by the reduction of expression of proinflammatory cytokines and return to their normal correlations, higher production of fibrogenic growth factors, restoration of balance in the expression of MMP-9 and TIMP-1/TIMP-2.
    MeSH term(s) Animals ; Cytokines/biosynthesis ; Epidermal Growth Factor/pharmacology ; Epidermis/drug effects ; Epidermis/metabolism ; Epidermis/pathology ; Humans ; Matrix Metalloproteinase 9/biosynthesis ; Rabbits ; Skin/injuries ; Skin Transplantation/pathology ; Wound Healing/drug effects
    Chemical Substances Cytokines ; Epidermal Growth Factor (62229-50-9) ; Matrix Metalloproteinase 9 (EC 3.4.24.35)
    Language Russian
    Publishing date 2002-01
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 127285-8
    ISSN 0004-1955
    ISSN 0004-1955
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Morfologicheskaia i immunogistokhimicheskaia kharakteristika reparativnykh protsessov v dlitel'no ne zazhivaiushchikh ranakh.

    Fedorov, D N / Ivashkin, A N / Shinin, V V / Vasil'ev, A V / Ivanov, A A

    Arkhiv patologii

    2002  Volume 64, Issue 1, Page(s) 8–11

    Abstract: Sluggish wounds (SW) are characterized by chronic inflammation, abnormal proportion of extracellular matrix (ECM) components, appearance of ECM components that do not occur under normal conditions, this preventing formation of basal membrane (BM) and ... ...

    Title translation Morphological and immunohistochemical characteristics of repair processes in nonhealing wounds.
    Abstract Sluggish wounds (SW) are characterized by chronic inflammation, abnormal proportion of extracellular matrix (ECM) components, appearance of ECM components that do not occur under normal conditions, this preventing formation of basal membrane (BM) and reepithelization of the wound. 89 biopsies from 25 patients with SW were studied before treatment and in different intervals after transplantation of allogenic cryopreserved epithelium on the wound. Decreased collagen type III content and accumulation of tenastcin in combination with low number of myofibroblasts were observed in ECM before the transplantation. Normalization of quantitative and qualitative composition of ECM components, BM formation, wound reepithelization without scarring were noted after the transplantation; myofibroblast number remained very low. Wound healing without contraction and scarring is a distinctive feature of reparative process in SW when allogenic cryopreserved epidermis is used.
    MeSH term(s) Extracellular Matrix/metabolism ; Extracellular Matrix/pathology ; Granulation Tissue/metabolism ; Granulation Tissue/pathology ; Humans ; Immunohistochemistry ; Skin Transplantation/pathology ; Time Factors ; Wound Healing
    Language Russian
    Publishing date 2002-01
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 127285-8
    ISSN 0004-1955
    ISSN 0004-1955
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online: Progress in developing a spiral fiber tracker for the J-PARC E36 experiment

    Tabata, Makoto / Horie, Keito / Igarashi, Youichi / Imazato, Jun / Ito, Hiroshi / Ivashkin, Alexander / Kawai, Hideyuki / Kudenko, Yury / Mineev, Oleg / Shimizu, Suguru / Toyoda, Akihisa / Yamazaki, Hirohito

    2014  

    Abstract: This paper reports the recent progress made in developing a spiral fiber tracker (SFT) for use in the E36 experiment scheduled at the Japan Proton Accelerator Research Complex (J-PARC). The primary goal of this positive kaon decay experiment, which uses ... ...

    Abstract This paper reports the recent progress made in developing a spiral fiber tracker (SFT) for use in the E36 experiment scheduled at the Japan Proton Accelerator Research Complex (J-PARC). The primary goal of this positive kaon decay experiment, which uses a stopped kaon beam, is to test lepton flavor universality to search for physics beyond the Standard Model of particle physics. For this experiment, we are currently upgrading the E246 apparatus, which consists of the superconducting toroidal spectrometer previously used at the High Energy Accelerator Research Organization (KEK), Japan. Conducting high-precision measurements will rely on efficiently detecting and tracking charged particles (i.e., positive muons and positrons) from kaon decays. Combined with the three existing layers of multiwire proportional chambers, the SFT comprises four layers of ribbons, with each layer containing 1-mm-diameter double-clad plastic scintillating fibers; the ribbons are spirally wound in two helicities around the kaon stopping target at the center of the detector system. Scintillation photons are read out by multipixel photon counters connected to the scintillating fibers by clear optical fiber extensions. A preliminary bench test shows that a prototype two-layer fiber ribbon exhibits 99.6% detection efficiency at the 1-photoelectron threshold. Finally, the SFT was successfully assembled around the target holder.

    Comment: Proceedings of 3rd International Conference on Technology and Instrumentation in Particle Physics (TIPP 2014), 4 pages, 2 figures
    Keywords Physics - Instrumentation and Detectors ; High Energy Physics - Experiment ; Nuclear Experiment
    Subject code 621
    Publishing date 2014-11-24
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Vliianie obshchego i lokal'nogo oblucheniia, modifitsirovannogo giperglikemieĭ, na metastazirovanie kartsinosarkomy Uoker 256 u krys.

    Kutlimuratov, A B / Ivashkin, A V / Zakirkhodzhaev, U D

    Eksperimental'naia onkologiia

    1990  Volume 12, Issue 2, Page(s) 76–79

    Abstract: It has been shown that the local radiation therapy, and also radiation therapy modified by the short-term hyperglycemia really increase the life-span of rats with Walker 256 carcinosarcoma. At the same time the metastatic process also increases, ... ...

    Title translation The effect of whole-body and local irradiation, modified by hyperglycemia, on the metastasis of Walker carcinosarcoma 256 in rats.
    Abstract It has been shown that the local radiation therapy, and also radiation therapy modified by the short-term hyperglycemia really increase the life-span of rats with Walker 256 carcinosarcoma. At the same time the metastatic process also increases, especially after the modified radiation therapy. The total irradiation of experimental animals in a dose of 50 sGy before the modified radiation therapy considerably decreases the frequency of metastatic process. A conclusion is drawn that the total irradiation has a prophylactic influence on metastases under conditions of modified radiation therapy.
    MeSH term(s) Animals ; Blood Glucose/analysis ; Carcinoma 256, Walker/blood ; Carcinoma 256, Walker/mortality ; Carcinoma 256, Walker/radiotherapy ; Combined Modality Therapy ; Female ; Glucose/administration & dosage ; Lymphatic Metastasis ; Radiotherapy Dosage ; Rats ; Time Factors ; Whole-Body Irradiation
    Chemical Substances Blood Glucose ; Glucose (IY9XDZ35W2)
    Language Russian
    Publishing date 1990
    Publishing country Ukraine
    Document type Comparative Study ; English Abstract ; Journal Article
    ZDB-ID 603099-3
    ISSN 0204-3564
    ISSN 0204-3564
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  8. Article ; Online: Directed, Elliptic, and Higher Order Flow Harmonics of Protons, Deuterons, and Tritons in Au+Au Collisions at sqrt[s_{NN}]=2.4  GeV.

    Adamczewski-Musch, J / Arnold, O / Behnke, C / Belounnas, A / Belyaev, A / Berger-Chen, J C / Blanco, A / Blume, C / Böhmer, M / Bordalo, P / Chernenko, S / Chlad, L / Ciepal, I / Deveaux, C / Dreyer, J / Epple, E / Fabbietti, L / Fateev, O / Filip, P /
    Fonte, P / Franco, C / Friese, J / Fröhlich, I / Galatyuk, T / Garzón, J A / Gernhäuser, R / Golosov, O / Golubeva, M / Greifenhagen, R / Guber, F / Gumberidze, M / Harabasz, S / Heinz, T / Hennino, T / Hlavac, S / Höhne, C / Holzmann, R / Ierusalimov, A / Ivashkin, A / Kämpfer, B / Karavicheva, T / Kardan, B / Koenig, I / Koenig, W / Kohls, M / Kolb, B W / Korcyl, G / Kornakov, G / Kornas, F / Kotte, R / Kugler, A / Kunz, T / Kurepin, A / Kurilkin, A / Kurilkin, P / Ladygin, V / Lalik, R / Lapidus, K / Lebedev, A / Lopes, L / Lorenz, M / Mahmoud, T / Maier, L / Malige, A / Mamaev, M / Mangiarotti, A / Markert, J / Matulewicz, T / Maurus, S / Metag, V / Michel, J / Mihaylov, D M / Morozov, S / Müntz, C / Münzer, R / Naumann, L / Nowakowski, K / Parpottas, Y / Pechenov, V / Pechenova, O / Petukhov, O / Piasecki, K / Pietraszko, J / Przygoda, W / Pysz, K / Ramos, S / Ramstein, B / Rathod, N / Reshetin, A / Rodriguez-Ramos, P / Rosier, P / Rost, A / Rustamov, A / Sadovsky, A / Salabura, P / Scheib, T / Schuldes, H / Schwab, E / Scozzi, F / Seck, F / Sellheim, P / Selyuzhenkov, I / Siebenson, J / Silva, L / Singh, U / Smyrski, J / Sobolev, Yu G / Spataro, S / Spies, S / Ströbele, H / Stroth, J / Sturm, C / Svoboda, O / Szala, M / Tlusty, P / Traxler, M / Tsertos, H / Usenko, E / Wagner, V / Wendisch, C / Wiebusch, M G / Wirth, J / Wójcik, D / Zanevsky, Y / Zumbruch, P

    Physical review letters

    2020  Volume 125, Issue 26, Page(s) 262301

    Abstract: Flow coefficients v_{n} of the orders n=1-6 are measured with the High-Acceptance DiElectron Spectrometer (HADES) at GSI for protons, deuterons, and tritons as a function of centrality, transverse momentum, and rapidity in Au+Au collisions at sqrt[s_{NN}] ...

    Abstract Flow coefficients v_{n} of the orders n=1-6 are measured with the High-Acceptance DiElectron Spectrometer (HADES) at GSI for protons, deuterons, and tritons as a function of centrality, transverse momentum, and rapidity in Au+Au collisions at sqrt[s_{NN}]=2.4  GeV. Combining the information from the flow coefficients of all orders allows us to construct for the first time, at collision energies of a few GeV, a multidifferential picture of the angular emission pattern of these particles. It reflects the complicated interplay between the effect of the central fireball pressure on the emission of particles and their subsequent interaction with spectator matter. The high precision information on higher order flow coefficients is a major step forward in constraining the equation of state of dense baryonic matter.
    Language English
    Publishing date 2020-10-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.125.262301
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  9. Article ; Online: Electromagnetic Calorimeter for HADES Experiment

    Rodríguez-Ramos P. / Chlad L. / Epple E. / Fabbietti L. / Galatyuk T. / Golubeva M. / Guber F. / Hlaváč S. / Ivashkin A. / Kajetanowic M. / Kardan B. / Koenig W. / Korcyl G. / Kugler A. / Lapidus K. / Linev S. / Lisowski E. / Neiser A. / Ott O. /
    Otte O. / Pethukov O. / Pietraszko J. / Reshetin A. / Rost A. / Salabura P. / Sobolev Y.G. / Svoboda O. / Thomas A. / Tlusty P. / Traxler M.

    EPJ Web of Conferences, Vol 81, p

    2014  Volume 06009

    Abstract: Electromagnetic calorimeter (ECAL) is being developed to complement dilepton spectrometer HADES. ECAL will enable the HADES@FAIR experiment to measure data on neutral meson production in heavy ion collisions at the energy range of 2-10 AGeV on the beam ... ...

    Abstract Electromagnetic calorimeter (ECAL) is being developed to complement dilepton spectrometer HADES. ECAL will enable the HADES@FAIR experiment to measure data on neutral meson production in heavy ion collisions at the energy range of 2-10 AGeV on the beam of future accelerator SIS100@FAIR. We will report results of the last beam test with quasi-monoenergetic photons carried out in MAMI facility at Johannes Gutenberg Universität Mainz.
    Keywords Physics ; QC1-999 ; Science ; Q
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Electromagnetic Calorimeter for HADES Experiment

    Rodríguez-Ramos P. / Chlad L. / Epple E. / Fabbietti L. / Galatyuk T. / Golubeva M. / Guber F. / Hlaváč S. / Ivashkin A. / Kajetanowic M. / Kardan B. / Koenig W. / Korcyl G. / Kugler A. / Lapidus K. / Linev S. / Lisowski E. / Neiser A. / Ott O. /
    Otte O. / Pethukov O. / Pietraszko J. / Reshetin A. / Rost A. / Salabura P. / Sobolev Y.G. / Svoboda O. / Thomas A. / Tlusty P. / Traxler M.

    EPJ Web of Conferences, Vol 81, p

    2014  Volume 06009

    Abstract: Electromagnetic calorimeter (ECAL) is being developed to complement dilepton spectrometer HADES. ECAL will enable the HADES@FAIR experiment to measure data on neutral meson production in heavy ion collisions at the energy range of 2-10 AGeV on the beam ... ...

    Abstract Electromagnetic calorimeter (ECAL) is being developed to complement dilepton spectrometer HADES. ECAL will enable the HADES@FAIR experiment to measure data on neutral meson production in heavy ion collisions at the energy range of 2-10 AGeV on the beam of future accelerator SIS100@FAIR. We will report results of the last beam test with quasi-monoenergetic photons carried out in MAMI facility at Johannes Gutenberg Universität Mainz.
    Keywords Physics ; QC1-999 ; Science ; Q
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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