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  1. Article ; Online: Is Levetiracetam a Superior Anti-Seizure Medication in Pediatric Status Epilepticus?

    Iyer, Anand S

    Indian pediatrics

    2023  Volume 60, Issue 8, Page(s) 517–518

    MeSH term(s) Child ; Humans ; Levetiracetam/therapeutic use ; Anticonvulsants/therapeutic use ; Status Epilepticus/drug therapy ; Phenytoin/therapeutic use
    Chemical Substances Levetiracetam (44YRR34555) ; Anticonvulsants ; Phenytoin (6158TKW0C5)
    Language English
    Publishing date 2023-05-19
    Publishing country India
    Document type Journal Article ; Comment
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 859: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Noninvasive Ventilation in Seriously Ill Older Adults at the End of Life-The Evidence Remains Elusive.

    Iyer, Anand S

    JAMA internal medicine

    2020  Volume 181, Issue 1, Page(s) 102–103

    MeSH term(s) Aged ; Death ; Humans ; Noninvasive Ventilation ; Respiration, Artificial ; Terminal Care
    Language English
    Publishing date 2020-10-19
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2699338-7
    ISSN 2168-6114 ; 2168-6106
    ISSN (online) 2168-6114
    ISSN 2168-6106
    DOI 10.1001/jamainternmed.2020.5648
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.119: Show issues Location:
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  3. Article ; Online: The "Good" Home Death in Pulmonary Disease: Avoiding the "Bad" and the "Ugly".

    Iyer, Anand S

    Chest

    2020  Volume 158, Issue 2, Page(s) 449–450

    MeSH term(s) Humans ; Lung Diseases ; United States
    Language English
    Publishing date 2020-08-20
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2020.04.005
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    Ui III Zs.45: Show issues Location:
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    Zs.MO 349: Show issues

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  4. Article ; Online: End-of-Life Preferences in Older US Adults-Bridging the "What Matters" Chasm.

    Iyer, Anand S / Brown, Cynthia J

    JAMA network open

    2022  Volume 5, Issue 1, Page(s) e2142279

    MeSH term(s) Adult ; Aged ; Death ; Humans ; Middle Aged ; Terminal Care
    Language English
    Publishing date 2022-01-04
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2021.42279
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  5. Article ; Online: Cognitive behavioural therapy sessions approach ineffective for anxiety and depression in COPD: is the door closed for good?

    Yohannes, Abebaw Mengistu / Iyer, Anand S / Hoth, Karin Ferneyhough / Dransfield, Mark T

    The European respiratory journal

    2024  Volume 63, Issue 1

    MeSH term(s) Humans ; Depression/therapy ; Depression/psychology ; Psychosocial Intervention ; Anxiety/therapy ; Anxiety/psychology ; Cognitive Behavioral Therapy ; Pulmonary Disease, Chronic Obstructive/complications ; Pulmonary Disease, Chronic Obstructive/therapy ; Pulmonary Disease, Chronic Obstructive/psychology
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.01857-2023
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    Zs.A 2322: Show issues Location:
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    Zs.MO 292: Show issues

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  6. Article ; Online: Optimizing sexual reproductive health of men and women with cystic fibrosis: A systematic review.

    Iyer, Anand G / Yu, Benjamin / Reddy, Amit / Khera, Mohit

    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

    2024  

    Abstract: This systematic review summarizes the impact of cystic fibrosis (CF) on sexual and reproductive health (SRH) in males and females, covering pubertal development, hormonal function, family planning, and fertility. Included articles featured historical CF ... ...

    Abstract This systematic review summarizes the impact of cystic fibrosis (CF) on sexual and reproductive health (SRH) in males and females, covering pubertal development, hormonal function, family planning, and fertility. Included articles featured historical CF diagnostic criteria, preclinical or clinical data (retrospective cohorts or open label trials), while excluded articles lacked full text availability, explicit methodology, or comparisons between CF and non-CF patients. Genotype differences in CFTR mutations influenced symptom severity. Males with CF experienced delayed puberty, hypogonadism, infertility from obstructive azoospermia, and semen parameter issues. Female CF patients showed decreased fertility, possibly linked to disrupted ionic balance and ovarian cystic disease. Assistive reproductive technologies addressed fertility issues, but success varied based on disease severity and genotype. CFTR modulators aided pulmonary function and sexual health but require further assessment for fertility benefits.
    Language English
    Publishing date 2024-02-03
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2084724-5
    ISSN 1873-5010 ; 1569-1993
    ISSN (online) 1873-5010
    ISSN 1569-1993
    DOI 10.1016/j.jcf.2024.01.009
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    Zs.A 6028: Show issues Location:
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    Zs.MO 459: Show issues

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  7. Article ; Online: Web Exclusive. Annals On Call - COPD: What Clinicians Need to Know-Part 2.

    Centor, Robert M / Iyer, Anand S

    Annals of internal medicine

    2021  Volume 174, Issue 8, Page(s) OC1

    Language English
    Publishing date 2021-08-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/A20-0018
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    Ua VI Zs.178/2: Show issues Location:
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  8. Article ; Online: Web Exclusive. Annals On Call - COPD: What Clinicians Need to Know-Part 1.

    Centor, Robert M / Iyer, Anand S

    Annals of internal medicine

    2021  Volume 174, Issue 7, Page(s) OC1

    Language English
    Publishing date 2021-07-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/A20-0017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.178/2: Show issues Location:
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  9. Article ; Online: Somatostatin receptors and the associated intracellular machinery: the two sides of the coin.

    Campana, Claudia / Iyer, Anand M / Ferone, Diego / Gatto, Federico / Hofland, Leo J

    The Journal of endocrinology

    2024  Volume 260, Issue 3

    Abstract: Somatostatin receptors (SSTs) are widely expressed in pituitary tumors and neuroendocrine neoplasms (NENs) of different origins, i.e. the gastrointestinal tract and the thorax (lungs and thymus), thus representing a well-established target for medical ... ...

    Abstract Somatostatin receptors (SSTs) are widely expressed in pituitary tumors and neuroendocrine neoplasms (NENs) of different origins, i.e. the gastrointestinal tract and the thorax (lungs and thymus), thus representing a well-established target for medical treatment with SST ligands (SRLs). However, the response to SRLs is highly heterogeneous between tumors. Two main factors can contribute to this variability: (i) the differential SST expression among tumor types and (ii) the differential expression/modulation of the SST-related intracellular machinery. In this literature review, we provide an overview of available data on the variable expression of SSTs in pituitary tumors and NENs, together with the resulting clinical implications. Moreover, we aim to describe the complex intracellular machinery involved in SST signaling and trafficking. Particularly, we will focus on β-arrestins and describe their role in receptor internalization and recycling, as well as the various functions of these scaffold molecules in tumor pathogenesis and progression. This review highlights the interplay between membrane receptors and intracellular machinery, together with its role in determining the clinical behavior of the tumor and the response to treatment in patients with pituitary tumors or NENs.
    MeSH term(s) Humans ; Receptors, Somatostatin/metabolism ; Receptors, Somatostatin/therapeutic use ; Pituitary Neoplasms/drug therapy ; Neuroendocrine Tumors
    Chemical Substances Receptors, Somatostatin
    Language English
    Publishing date 2024-02-07
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 3028-4
    ISSN 1479-6805 ; 0022-0795
    ISSN (online) 1479-6805
    ISSN 0022-0795
    DOI 10.1530/JOE-23-0298
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh III Zs.133: Show issues Location:
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  10. Article ; Online: The Development and Potential Applications of an Automated Method for Detecting and Classifying Continuous Glucose Monitoring Patterns.

    Shomali, Mansur / Liu, Shiping / Kumbara, Abhimanyu / Iyer, Anand / Gao, Guodong Gordon

    Journal of diabetes science and technology

    2024  , Page(s) 19322968241232378

    Abstract: Introduction: Continuous glucose monitoring (CGM) is emerging as a transformative tool for helping people with diabetes self-manage their glucose and supporting clinicians in effective treatment. Unfortunately, many CGM users, and clinicians, find ... ...

    Abstract Introduction: Continuous glucose monitoring (CGM) is emerging as a transformative tool for helping people with diabetes self-manage their glucose and supporting clinicians in effective treatment. Unfortunately, many CGM users, and clinicians, find interpreting the large volume of CGM data to be overwhelming and complex. To address this challenge, an efficient, intelligent method for detecting and classifying discernable patterns in CGM data was desired.
    Methods: We developed an automated artificial intelligence (AI)-driven method to detect and classify different discernable CGM patterns which called "CGM events." We trained different models using 60 days of CGM data from 27 individuals with diabetes from a publicly available data set and then evaluated model performance using separate test data from the same group. Each event is classified according to clinical significance based on three parameters: (1) glucose category at or near the beginning of the CGM event; (2) a calculated severity score that encompasses both signal shape and temporal characteristics (e.g., how high the CGM curve goes (measured in mg/dL) and how long it stays above target (as established by published consensus guidelines); and (3) the glucose category at or near the end of the event.
    Results: The system accurately detected and classified events from actual CGM data. This was also validated with expert diabetes clinicians.
    Conclusions: Advanced pattern recognition methods can be used to detect and classify CGM events of interest and may be used to provide actionable insights and self-management support to CGM users and decision support to the clinicians caring for them.
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article
    ISSN 1932-2968
    ISSN (online) 1932-2968
    DOI 10.1177/19322968241232378
    Database MEDical Literature Analysis and Retrieval System OnLINE

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