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  1. Article ; Online: Exploring the evidence behind the comparable impact of the pneumococcal conjugate vaccines PHiD-CV and PCV13 on overall pneumococcal disease.

    Izurieta, Patricia / Nieto Guevara, Javier

    Human vaccines & immunotherapeutics

    2021  Volume 18, Issue 1, Page(s) 1872341

    Abstract: The worldwide implementation of pneumococcal conjugate vaccines (PCVs) in children has reduced the overall pneumococcal disease burden. Two PCVs are widely available for infant vaccination: the pneumococcal non- ... ...

    Abstract The worldwide implementation of pneumococcal conjugate vaccines (PCVs) in children has reduced the overall pneumococcal disease burden. Two PCVs are widely available for infant vaccination: the pneumococcal non-typeable
    MeSH term(s) Child ; Humans ; Infant ; Pneumococcal Infections/prevention & control ; Pneumococcal Vaccines ; Serogroup ; Streptococcus pneumoniae ; Vaccines, Conjugate ; Viral Vaccines
    Chemical Substances Pneumococcal Vaccines ; Vaccines, Conjugate ; Viral Vaccines
    Language English
    Publishing date 2021-02-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2664176-8
    ISSN 2164-554X ; 2164-5515
    ISSN (online) 2164-554X
    ISSN 2164-5515
    DOI 10.1080/21645515.2021.1872341
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6967: Show issues Location:
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  2. Article ; Online: Reply to '

    Nieto Guevara, Javier / Izurieta, Patricia

    Human vaccines & immunotherapeutics

    2020  Volume 16, Issue 9, Page(s) 2307–2308

    MeSH term(s) Child ; Colombia/epidemiology ; Humans ; Pneumococcal Infections/epidemiology ; Pneumococcal Infections/prevention & control ; Pneumococcal Vaccines ; Serogroup ; Streptococcus pneumoniae
    Chemical Substances 10-valent pneumococcal conjugate vaccine ; Pneumococcal Vaccines
    Language English
    Publishing date 2020-07-09
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2664176-8
    ISSN 2164-554X ; 2164-5515
    ISSN (online) 2164-554X
    ISSN 2164-5515
    DOI 10.1080/21645515.2020.1784654
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Underlying factors in paediatric invasive pneumococcal disease in Belgium.

    Izurieta, Patricia / Scherbakov, Michael / Vetter, Volker

    The Lancet. Infectious diseases

    2021  Volume 21, Issue 2, Page(s) 169–170

    MeSH term(s) Belgium/epidemiology ; Child ; Humans ; Pneumococcal Infections/epidemiology ; Pneumococcal Infections/prevention & control ; Pneumococcal Vaccines ; Retrospective Studies ; Vaccines, Conjugate
    Chemical Substances Pneumococcal Vaccines ; Vaccines, Conjugate
    Language English
    Publishing date 2021-01-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(20)30867-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5743: Show issues Location:
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  4. Article ; Online: Recommendation to Take a Holistic View of the Dynamic Pathogenic Pneumococcal Environment.

    Izurieta, Patricia / AbdelGhany, Mohammad / Paynter, Janine / Petousis-Harris, Helen

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2022  Volume 75, Issue 1, Page(s) e1204–e1205

    MeSH term(s) Humans ; Pneumococcal Infections/prevention & control ; Streptococcus pneumoniae
    Language English
    Publishing date 2022-03-02
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciac188
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Interpretation of the switch in a childhood pneumococcal vaccination programme from PCV13 to PCV10 in Belgium.

    Izurieta, Patricia / Breuer, Thomas

    The Lancet. Infectious diseases

    2018  Volume 18, Issue 8, Page(s) 831–832

    MeSH term(s) Belgium ; Immunization Programs ; Pneumococcal Vaccines ; Streptococcus pneumoniae ; Vaccination
    Chemical Substances 10-valent pneumococcal conjugate vaccine ; Pneumococcal Vaccines
    Language English
    Publishing date 2018-07-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(18)30410-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5743: Show issues Location:
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  6. Article ; Online: Systematic review of the efficacy, effectiveness and impact of high-valency pneumococcal conjugate vaccines on otitis media.

    Izurieta, Patricia / Scherbakov, Michael / Nieto Guevara, Javier / Vetter, Volker / Soumahoro, Lamine

    Human vaccines & immunotherapeutics

    2022  Volume 18, Issue 1, Page(s) 2013693

    Abstract: Otitis media (OM) is a common disease of childhood and available pneumococcal conjugate vaccines (PCVs), with different compositions, could have different impact on OM reduction. This systematic literature review evaluated available data describing the ... ...

    Abstract Otitis media (OM) is a common disease of childhood and available pneumococcal conjugate vaccines (PCVs), with different compositions, could have different impact on OM reduction. This systematic literature review evaluated available data describing the efficacy, effectiveness, and impact of 10-valent pneumococcal
    MeSH term(s) Child ; Humans ; Otitis Media/prevention & control ; Pneumococcal Infections/prevention & control ; Vaccination ; Vaccines, Conjugate
    Chemical Substances Vaccines, Conjugate
    Language English
    Publishing date 2022-01-12
    Publishing country United States
    Document type Journal Article ; Systematic Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2664176-8
    ISSN 2164-554X ; 2164-5515
    ISSN (online) 2164-554X
    ISSN 2164-5515
    DOI 10.1080/21645515.2021.2013693
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Response to: Pneumococcal conjugate vaccines in Latin America: are PCV10 and PCV13 similar in terms of protection against serotype 19A?

    Guevara, Javier Nieto / Izurieta, Patricia / Hoet, Bernard

    Expert review of vaccines

    2018  Volume 17, Issue 4, Page(s) 283–284

    MeSH term(s) Humans ; Infant ; Latin America ; Pneumococcal Infections ; Pneumococcal Vaccines ; Serogroup ; Streptococcus pneumoniae/immunology ; Vaccines, Conjugate
    Chemical Substances 10-valent pneumococcal conjugate vaccine ; Pneumococcal Vaccines ; Vaccines, Conjugate
    Language English
    Publishing date 2018-04-06
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2181284-6
    ISSN 1744-8395 ; 1476-0584
    ISSN (online) 1744-8395
    ISSN 1476-0584
    DOI 10.1080/14760584.2018.1459247
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6077: Show issues Location:
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  8. Article ; Online: Estimated public health impact of human rotavirus vaccine (HRV) and pneumococcal polysaccharide protein D-conjugate vaccine (PHiD-CV) on child morbidity and mortality in Gavi-supported countries.

    Marijam, Alen / Schuerman, Lode / Izurieta, Patricia / Pereira, Priya / Van Oorschot, Désirée / Mehta, Shailesh / Ota, Martin Oc / Standaert, Baudouin

    Human vaccines & immunotherapeutics

    2022  , Page(s) 2135916

    Abstract: Vaccine impact models against rotavirus disease (RD) and pneumococcal disease (PD) in low- and middle-income countries assume vaccine coverage based on other vaccines. We propose to assess the impact on severe disease cases and deaths avoided based on ... ...

    Abstract Vaccine impact models against rotavirus disease (RD) and pneumococcal disease (PD) in low- and middle-income countries assume vaccine coverage based on other vaccines. We propose to assess the impact on severe disease cases and deaths avoided based on vaccine doses delivered by one manufacturer to Gavi-supported countries. From the number of human rotavirus vaccine (HRV) and pneumococcal polysaccharide protein D-conjugate vaccine (PHiD-CV) doses delivered, we estimated the averted burden of disease 1) in a specific year and 2) for all children vaccinated during the study period followed-up until 5 years (y) of age. Uncertainty of the estimated impact was assessed in a probabilistic sensitivity analysis using Monte-Carlo simulations to provide 95% confidence intervals. From 2009 to 2019, approximately 143 million children received HRV in 57 Gavi-supported countries, avoiding an estimated 18.7 million severe RD cases and 153,000, deaths. From 2011 to 2019, approximately 146 million children received PHiD-CV in 36 countries, avoiding an estimated 5.0 million severe PD cases and 587,000 deaths. The number of severe cases and deaths averted for all children vaccinated during the study period until 5 years of age were about 23.2 million and 190,000, respectively, for HRV, and 6.6 million and 749,000, respectively, for PHiD-CV. Models based on doses delivered help to assess the impact of vaccination, plan vaccination programs and understand public health benefits. In 2019, HRV and PHiD-CV doses delivered over a 5-y period may have, on average, averted nine severe disease cases every minute and one child death every 4 min.
    Language English
    Publishing date 2022-12-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2664176-8
    ISSN 2164-554X ; 2164-5515
    ISSN (online) 2164-554X
    ISSN 2164-5515
    DOI 10.1080/21645515.2022.2135916
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6967: Show issues Location:
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  9. Article ; Online: Public health impact of pneumococcal conjugate vaccine infant immunization programs: assessment of invasive pneumococcal disease burden and serotype distribution.

    Izurieta, Patricia / Bahety, Priti / Adegbola, Richard / Clarke, Christopher / Hoet, Bernard

    Expert review of vaccines

    2018  Volume 17, Issue 6, Page(s) 479–493

    Abstract: Introduction: Pneumococcal conjugate vaccine (PCV) impact studies have reported substantial reductions in the incidence of invasive pneumococcal disease (IPD) after implementation of childhood PCV programs. Heterogeneity in surveillance systems, local ... ...

    Abstract Introduction: Pneumococcal conjugate vaccine (PCV) impact studies have reported substantial reductions in the incidence of invasive pneumococcal disease (IPD) after implementation of childhood PCV programs. Heterogeneity in surveillance systems, local epidemiology and PCV programs hampers comparisons between studies. We aimed to better understand the impact of childhood PCV programs on overall IPD and serotype distribution.
    Areas covered: We analyzed the impact of PCV programs on the incidence of overall IPD, and the distribution of vaccine serotypes (VT) and non-vaccine serotypes (NVT) in children <5 years and adults ≥65 years old. We retrieved datasets from observational post-marketing studies and surveillance reports from countries with high-quality surveillance data available for at least 2 years before PCV program initiation and 3 years after higher-valent PCV implementation. We harmonized pre- and post-PCV analysis periods and assessment methods.
    Expert commentary: After introduction of pediatric PCV programs, the residual overall IPD burden in children was low and in a narrow range across countries with high vaccination coverage, irrespective of differences in PCV programs and pneumococcal epidemiology. Effects on overall IPD were more variable in the elderly. Whereas IPD was mainly due to VTs before PCV introduction, NVTs are the major contributor today in children and adults.
    MeSH term(s) Aged ; Child, Preschool ; Humans ; Immunization Programs ; Incidence ; Infant ; Pneumococcal Infections/epidemiology ; Pneumococcal Infections/prevention & control ; Pneumococcal Vaccines/administration & dosage ; Public Health ; Vaccination Coverage/statistics & numerical data ; Vaccines, Conjugate/administration & dosage
    Chemical Substances Pneumococcal Vaccines ; Vaccines, Conjugate
    Language English
    Publishing date 2018-06-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2181284-6
    ISSN 1744-8395 ; 1476-0584
    ISSN (online) 1744-8395
    ISSN 1476-0584
    DOI 10.1080/14760584.2018.1413354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: CIRCULATING CLONAL COMPLEXES AND SEQUENCE TYPES OF STREPTOCOCCUS PNEUMONIAE SEROTYPE 19A WORLDWIDE: THE IMPORTANCE OF MULTIDRUG RESISTANCE: A SYSTEMATIC LITERATURE REVIEW.

    Ruiz García, Yara / Nieto Guevara, Javier / Izurieta, Patricia / Vojtek, Ivo / Ortega-Barría, Eduardo / Guzman-Holst, Adriana

    Expert review of vaccines

    2021  Volume 20, Issue 1, Page(s) 45–57

    Abstract: Introduction: Streptococcus pneumoniae: Areas covered: We performed a systematic literature review to analyze the frequency and clonal distribution of serotype 19A isolates in the pre- and post-PCV era worldwide providing a scientific background on ... ...

    Abstract Introduction: Streptococcus pneumoniae
    Areas covered: We performed a systematic literature review to analyze the frequency and clonal distribution of serotype 19A isolates in the pre- and post-PCV era worldwide providing a scientific background on the factors that influence multidrug resistance in pneumococcal isolates.
    Expert commentary: Serotype 19A IPD incidence increased in all regions following the introduction of the 7-valent PCV. The higher-valent PCVs have reduced the rates of 19A IPD isolates, but several circulating strains with diverse antibiotic resistance prevailed. Heterogeneous clonal distribution in serotype 19A was observed within countries and regions, irrespective of higher-valent PCV used. An increase of 19A isolates from pre- to post-vaccination periods were associated with frequently occurring serotype switching events and with the prevalence of multidrug resistant strains. Rational antibiotic policies must be implemented to control the emergence of resistance.
    MeSH term(s) Aged ; Anti-Bacterial Agents/pharmacology ; Child ; Drug Resistance, Multiple, Bacterial ; Humans ; Incidence ; Pneumococcal Infections/drug therapy ; Pneumococcal Infections/microbiology ; Pneumococcal Infections/prevention & control ; Pneumococcal Vaccines/administration & dosage ; Pneumococcal Vaccines/immunology ; Serogroup ; Streptococcus pneumoniae/drug effects ; Streptococcus pneumoniae/immunology ; Streptococcus pneumoniae/isolation & purification ; Vaccination ; Vaccines, Conjugate/administration & dosage
    Chemical Substances Anti-Bacterial Agents ; Pneumococcal Vaccines ; Vaccines, Conjugate
    Language English
    Publishing date 2021-02-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 2181284-6
    ISSN 1744-8395 ; 1476-0584
    ISSN (online) 1744-8395
    ISSN 1476-0584
    DOI 10.1080/14760584.2021.1873136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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