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  1. Book: Mensch, Körper, Krankheit

    Raichle, Gerda / Menche, Nicole / Huch, Renate / Jürgens, Klaus Dieter

    Anatomie, Physiologie, Krankheitsbilder

    2022  

    Author's details herausgegeben von: Prof. Dr. med. Dr. med. h.c. mult. Renate Huch (Zürich), Prof. Dr.-Ing. Dr. rer. biol. hum. habil. Klaus D. Jürgens (Hannover) ; Grafiken von: Gerda Raichle (Ulm) ; mit Beiträgen von: Prof. Dr. med. Renate Huch [und 5 anderen] ; unter Mitarbeit von: Dr. med. Nicole Menche (Langen)
    Keywords Generalistische Pflegeausbildung ; Heilpraktikerausbildung ; Gesundheit ; Anatomie ; Auszubildende in medizinischen Berufen ; Ergotherapeuten ; Heilpraktiker ; Interessierte Laien ; Krankenpflege ; Physiologie ; Pathologie ; Gesundheitswesen ; Beruf
    Subject Berufe ; Gesundheitsdienst ; Gesundheitssystem ; Gesundheitswirtschaft ; Medizinalwesen ; Medizinalsystem ; Allgemeine Pathologie ; Spezielle Pathologie ; Klinische Pathologie ; Allgemeine Krankheitslehre ; Humanphysiologie ; Mensch ; Körperfunktion ; Tiere ; Tieranatomie ; Kunst der Zergliederung ; Zergliederungskunst
    Language German
    Size 510 Seiten, Illustrationen
    Edition 9. Auflage
    Publisher Elsevier
    Publishing place München, Deutschland
    Publishing country Germany
    Document type Book
    Note Mit Freischalt-Code zu Online-Inhalten
    Old title Vorangegangen ist Mensch, Körper, Krankheit
    HBZ-ID HT021408311
    ISBN 978-3-437-26795-6 ; 3-437-26795-7 ; 9783437096877 ; 3437096877
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Mensch, Körper, Krankheit

    Raichle, Gerda / Huch, Renate / Jürgens, Klaus Dieter

    Anatomie, Physiologie, Krankheitsbilder

    2019  

    Author's details herausgegeben von: Prof. Dr. med. Dr. med. h.c. mult. Renate Huch (Zürich), Prof. Dr.-Ing. Dr. rer. biol. hum. habil. Klaus D. Jürgens (Hannover) ; Grafiken von: Gerda Raichle (Ulm) ; mit Beiträgen von: Prof. Dr. med. Renate Huch (Zürich) [und weiteren]
    Keywords Anatomie ; Auszubildende in medizinischen Berufen ; Ergotherapeuten ; Gesundheit ; Heilpraktiker ; Interessierte Laien ; Krankenpflege ; Physiologie ; Pathologie ; Gesundheitswesen ; Beruf
    Subject Berufe ; Gesundheitsdienst ; Gesundheitssystem ; Gesundheitswirtschaft ; Medizinalwesen ; Medizinalsystem ; Allgemeine Pathologie ; Spezielle Pathologie ; Klinische Pathologie ; Allgemeine Krankheitslehre ; Humanphysiologie ; Mensch ; Körperfunktion ; Tiere ; Tieranatomie ; Kunst der Zergliederung ; Zergliederungskunst
    Subject code 610
    Language German
    Size 508 Seiten, Illustrationen, Diagramme
    Edition 8. Auflage
    Publisher Elsevier
    Publishing place München
    Publishing country Germany
    Document type Book
    Old title Vorangegangen ist
    HBZ-ID HT020137418
    ISBN 978-3-437-26794-9 ; 3-437-26794-9 ; 9783437098024 ; 3437098020
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Mensch, Körper, Krankheit

    Hasel, Hubert / Koop, Maren / Munk, Katharina / Renz-Polster, Herbert / Fessel, Dodo / Calia, Giulio / Gold, Kai / Beck-Schimmer, Beatrice / Menche, Nicole / Weyers, Imke / Huch, Renate / Jürgens, Klaus Dieter

    Anatomie, Physiologie, Krankheitsbilder : Lehrbuch und Atlas für die Berufe im Gesundheistwesen

    2015  

    Author's details hrsg. von Renate Huch ; Klaus D. Jürgens. Mit Beiträgen von Hubert Hasel ; Maren Koop ; Katharina Munk ; Herbert Renz-Polster ; Dodo Fessel. Unter Mitarb. von Giulio Calia ; Kai Gold ; Beatrice Beck-Schimmer ; Nicole Menche ; Imke Weyers
    Keywords Anatomie ; Gesundheit ; Laien ; Krankenpflege ; Krankheitslehre ; Physiologie ; Rettungssanitäter ; Pathologie ; Gesundheitswesen ; Beruf
    Subject Humanphysiologie ; Mensch ; Körperfunktion ; Tiere ; Tieranatomie ; Kunst der Zergliederung ; Zergliederungskunst ; Berufe ; Gesundheitsdienst ; Gesundheitssystem ; Gesundheitswirtschaft ; Medizinalwesen ; Medizinalsystem ; Allgemeine Pathologie ; Spezielle Pathologie ; Klinische Pathologie ; Allgemeine Krankheitslehre
    Language German
    Size 488 S. : Ill., graf. Darst., 300 mm x 240 mm
    Edition 7. Aufl.
    Publisher Urban & Fischer in Elsevier
    Publishing place München
    Publishing country Germany
    Document type Book
    Accompanying material Zugang zu zusätzlichem Internetmaterial über Code
    HBZ-ID HT018505257
    ISBN 978-3-437-26793-2 ; 3-437-26793-0 ; 9783437188763 ; 9783437295980 ; 3437188763 ; 3437295985
    Database Catalogue ZB MED Medicine, Health

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  4. Article: Etruscan shrew muscle: the consequences of being small.

    Jürgens, Klaus D

    The Journal of experimental biology

    2002  Volume 205, Issue Pt 15, Page(s) 2161–2166

    Abstract: The skeletal muscles of the smallest mammal, the Etruscan shrew Suncus etruscus, are functionally and structurally adapted to the requirements of an enormously high energy turnover. Isometric twitch contractions of the extensor digitorum longus (EDL) and ...

    Abstract The skeletal muscles of the smallest mammal, the Etruscan shrew Suncus etruscus, are functionally and structurally adapted to the requirements of an enormously high energy turnover. Isometric twitch contractions of the extensor digitorum longus (EDL) and soleus muscles are shorter than in any other mammal, allowing these muscles to contract at outstandingly high frequencies. The skeletal muscles of S. etruscus contract at up to 900 min(-1) for respiration, up to 780 min(-1) for running and up to 3500 min(-1) for shivering. All skeletal muscles investigated lack slow-twitch type I fibres and consist only of fast-twitch type IID fibres. These fibres are optimally equipped with properties enabling a high rate of almost purely oxidative metabolism: they have a small diameter, their citrate synthase activity is higher and their lactate dehydrogenase activity is lower than in the muscles of any other mammal and they have a rapid shortening velocity. Differences in isometric twitch contraction times between different muscles are, at least in part, probably due to differences in cytosolic creatine kinase activities.
    MeSH term(s) Animals ; Body Constitution/physiology ; Energy Metabolism ; Isometric Contraction ; Muscle, Skeletal/physiology ; Shrews/physiology
    Language English
    Publishing date 2002-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 218085-6
    ISSN 1477-9145 ; 0022-0949
    ISSN (online) 1477-9145
    ISSN 0022-0949
    DOI 10.1242/jeb.205.15.2161
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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  5. Article ; Online: Significance of myoglobin as an oxygen store and oxygen transporter in the intermittently perfused human heart: a model study.

    Endeward, Volker / Gros, Gerolf / Jürgens, Klaus D

    Cardiovascular research

    2010  Volume 87, Issue 1, Page(s) 22–29

    Abstract: Aims: The mechanisms by which the left ventricular wall escapes anoxia during the systolic phase of low blood perfusion are investigated, especially the role of myoglobin (Mb), which can (i) store oxygen and (ii) facilitate intracellular oxygen ... ...

    Abstract Aims: The mechanisms by which the left ventricular wall escapes anoxia during the systolic phase of low blood perfusion are investigated, especially the role of myoglobin (Mb), which can (i) store oxygen and (ii) facilitate intracellular oxygen transport. The quantitative role of these two Mb functions is studied in the maximally working human heart.
    Methods and results: Because discrimination between Mb functions has not been achieved experimentally, we use a Krogh cylinder model here. At a heart rate of 200 beats/min and a 1:1 ratio of diastole/systole, the systole lasts for 150 ms. The basic model assumption is that, with mobile Mb, the oxygen stored in the end-diastolic left ventricle wall exactly meets the demand during the 150 ms of systolic cessation of blood flow. The coronary blood flow necessary to achieve this agrees with literature data. By considering Mb immobile or setting its concentration to zero, respectively, we find that, depending on Mb concentration, Mb-facilitated O(2) transport maintains O(2) supply to the left ventricle wall during 22-34 of the 150 ms, while Mb storage function accounts for a further 12-17 ms. When Mb is completely absent, anoxia begins to develop after 116-99 ms.
    Conclusion: While Mb plays no significant role during diastole, it supplies O(2) to the left ventricular wall for < or = 50 ms of the 150 ms systole, whereas capillary haemoglobin is responsible for approximately 80 ms. Slight increases in haemoglobin concentration, blood flow, or capillary density can compensate the absence of Mb, a finding which agrees well with the observations using Mb knockout mice.
    MeSH term(s) Adaptation, Physiological ; Animals ; Coronary Circulation ; Diffusion ; Heart Rate ; Heart Ventricles/metabolism ; Hemoglobins/metabolism ; Humans ; Mice ; Mice, Knockout ; Microcirculation ; Models, Cardiovascular ; Myocardial Contraction ; Myocardium/metabolism ; Myoglobin/blood ; Myoglobin/deficiency ; Myoglobin/genetics ; Oxygen/blood ; Oxygen Consumption ; Reproducibility of Results ; Sarcoplasmic Reticulum/metabolism ; Time Factors ; Ventricular Function, Left
    Chemical Substances Hemoglobins ; Myoglobin ; Oxygen (S88TT14065)
    Language English
    Publishing date 2010-07-01
    Publishing country England
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80340-6
    ISSN 1755-3245 ; 0008-6363
    ISSN (online) 1755-3245
    ISSN 0008-6363
    DOI 10.1093/cvr/cvq036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Physiologie

    Bartels, Rut / Bartels, Heinz / Jürgens, Klaus D

    Lehrbuch der Funktionen des menschlichen Körpers ; 25 Tabellen

    2004  

    Abstract: Das komplizierte Gebilde Mensch zu kennen und zu verstehen ist eine Grundvoraussetzung für medizinische und pflegerische Ausbildungsberufe. Neben den differenzierten Abläufen und Zusammenhängen der normalen Physiologie finden Sie auch krankhafte ... ...

    Author's details Rut Bartels; Heinz Bartels. Hrsg. von Klaus D. Jürgens
    Abstract Das komplizierte Gebilde Mensch zu kennen und zu verstehen ist eine Grundvoraussetzung für medizinische und pflegerische Ausbildungsberufe. Neben den differenzierten Abläufen und Zusammenhängen der normalen Physiologie finden Sie auch krankhafte Veränderungen und Hinweise zur Prävention einprägsam dargestellt. Neu in der 7. Auflage: -Inhalte komplett überarbeitet und aktualisiert; -Viele neue Untersuchungsverfahren hinzugefügt; -Hinweise zur Pathophysiologie und Prävention
    Keywords Physiologie
    Language German
    Size 398 S., Ill., graph. Darst.
    Edition 7., überarb. Aufl.
    Publisher Elsevier, Urban & Fischer
    Publishing place München
    Document type Book
    Note Hier auch später erschienene, unveränderte Nachdrucke
    ISBN 3437266411 ; 9783437266416
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  7. Book: Physiologie

    Bartels, Rut / Bartels, Heinz / Jürgens, Klaus D

    Lehrbuch der Funktionen des menschlichen Körpers ; 25 Tabellen

    2004  

    Abstract: Das komplizierte Gebilde Mensch zu kennen und zu verstehen ist eine Grundvoraussetzung für medizinische und pflegerische Ausbildungsberufe. Neben den differenzierten Abläufen und Zusammenhängen der normalen Physiologie finden Sie auch krankhafte ... ...

    Author's details Rut Bartels; Heinz Bartels. Hrsg. von Klaus D. Jürgens
    Abstract Das komplizierte Gebilde Mensch zu kennen und zu verstehen ist eine Grundvoraussetzung für medizinische und pflegerische Ausbildungsberufe. Neben den differenzierten Abläufen und Zusammenhängen der normalen Physiologie finden Sie auch krankhafte Veränderungen und Hinweise zur Prävention einprägsam dargestellt. Neu in der 7. Auflage: -Inhalte komplett überarbeitet und aktualisiert; -Viele neue Untersuchungsverfahren hinzugefügt; -Hinweise zur Pathophysiologie und Prävention
    Keywords Physiologie
    Language German
    Size 398 S., Ill., graph. Darst.
    Edition 7., überarb. Aufl.
    Publisher Elsevier, Urban & Fischer
    Publishing place München
    Document type Book
    Note Hier auch später erschienene, unveränderte Nachdrucke
    ISBN 3437266411 ; 9783437266416
    Database Former special subject collection: coastal and deep sea fishing

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  8. Book: Physiologie

    Bartels, Heinz / Bartels, Rut / Jürgens, Klaus D

    1998  

    Author's details Heinz Bartels und Rut Bartels. Unter Mitarb. von Klaus D. Jürgens. [Zeichn.: Günther Marks ...]
    Keywords Physiologie
    Language German
    Size X, 406 S., Ill., graph. Darst., 24 cm
    Edition 6., überarb. Aufl.
    Publisher Urban & Schwarzenberg
    Publishing place München u.a.
    Document type Book
    ISBN 3541090561 ; 9783541090563
    Database Former special subject collection: coastal and deep sea fishing

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  9. Article: Myoglobin: Just an Oxygen Store or Also an Oxygen Transporter?

    Jürgens, Klaus D. / Papadopoulos, Simon / Peters, Thomas / Gros, Gerolf

    News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

    2001  Volume 15, Page(s) 269–274

    Abstract: Besides acting as an oxygen store during times of reduced blood oxygen supply, myoglobin can also facilitate intracellular oxygen transport by diffusion of oxymyoglobin along a PO(2) gradient. We reassess the importance of myoglobin-facilitated oxygen ... ...

    Abstract Besides acting as an oxygen store during times of reduced blood oxygen supply, myoglobin can also facilitate intracellular oxygen transport by diffusion of oxymyoglobin along a PO(2) gradient. We reassess the importance of myoglobin-facilitated oxygen diffusion by applying new findings on the intracellular diffusivity of myoglobin in a model calculation.
    Language English
    Publishing date 2001-05-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632842-8
    ISSN 1522-161X ; 0886-1714
    ISSN (online) 1522-161X
    ISSN 0886-1714
    DOI 10.1152/physiologyonline.2000.15.5.269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2164: Show issues Location:
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  10. Article: Dipalmitoylphosphatidylcholine is not the major surfactant phospholipid species in all mammals.

    Lang, Carol J / Postle, Anthony D / Orgeig, Sandra / Possmayer, Fred / Bernhard, Wolfgang / Panda, Amiya K / Jürgens, Klaus D / Milsom, William K / Nag, Kaushik / Daniels, Christopher B

    American journal of physiology. Regulatory, integrative and comparative physiology

    2005  Volume 289, Issue 5, Page(s) R1426–39

    Abstract: Pulmonary surfactant, a complex mixture of lipids and proteins, lowers the surface tension in terminal air spaces and is crucial for lung function. Within an animal species, surfactant composition can be influenced by development, disease, respiratory ... ...

    Abstract Pulmonary surfactant, a complex mixture of lipids and proteins, lowers the surface tension in terminal air spaces and is crucial for lung function. Within an animal species, surfactant composition can be influenced by development, disease, respiratory rate, and/or body temperature. Here, we analyzed the composition of surfactant in three heterothermic mammals (dunnart, bat, squirrel), displaying different torpor patterns, to determine: 1) whether increases in surfactant cholesterol (Chol) and phospholipid (PL) saturation occur during long-term torpor in squirrels, as in bats and dunnarts; 2) whether surfactant proteins change during torpor; and 3) whether PL molecular species (molsp) composition is altered. In addition, we analyzed the molsp composition of a further nine mammals (including placental/marsupial and hetero-/homeothermic contrasts) to determine whether phylogeny or thermal behavior determines molsp composition in mammals. We discovered that like bats and dunnarts, surfactant Chol increases during torpor in squirrels. However, changes in PL saturation during torpor may not be universal. Torpor was accompanied by a decrease in surfactant protein A in dunnarts and squirrels, but not in bats, whereas surfactant protein B did not change in any species. Phosphatidylcholine (PC)16:0/16:0 is highly variable between mammals and is not the major PL in the wombat, dunnart, shrew, or Tasmanian devil. An inverse relationship exists between PC16:0/16:0 and two of the major fluidizing components, PC16:0/16:1 and PC16:0/14:0. The PL molsp profile of an animal species is not determined by phylogeny or thermal behavior. We conclude that there is no single PL molsp composition that functions optimally in all mammals; rather, surfactant from each animal is unique and tailored to the biology of that animal.
    MeSH term(s) 1,2-Dipalmitoylphosphatidylcholine/physiology ; Animals ; Body Temperature ; Chiroptera/physiology ; Cholesterol/analysis ; Cholesterol/physiology ; Cold Temperature ; Humans ; Macropodidae ; Male ; Marsupialia/physiology ; Phascolarctidae ; Phospholipids/analysis ; Phospholipids/physiology ; Phylogeny ; Pulmonary Surfactants/chemistry ; Pulmonary Surfactants/metabolism ; Rabbits ; Rats ; Rats, Sprague-Dawley ; Sciuridae/physiology ; Shrews ; Species Specificity ; Swine
    Chemical Substances Phospholipids ; Pulmonary Surfactants ; 1,2-Dipalmitoylphosphatidylcholine (2644-64-6) ; Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2005-07-21
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603839-6
    ISSN 1522-1490 ; 0363-6119
    ISSN (online) 1522-1490
    ISSN 0363-6119
    DOI 10.1152/ajpregu.00496.2004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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