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  1. Article ; Online: Barriers to hand hygiene compliance in intensive care units during the COVID-19 pandemic: A qualitative study.

    Ahmadipour, Maryam / Dehghan, Mahlagha / Ahmadinejad, Mehdi / Jabarpour, Maryam / Mangolian Shahrbabaki, Parvin / Ebrahimi Rigi, Zahra

    Frontiers in public health

    2022  Volume 10, Page(s) 968231

    Abstract: Background: The practice of hand washing is an effective way to prevent contamination and disease transmission. Following the COVID-19 pandemic, hand washing has become increasingly important. Therefore, this qualitative study aimed to understand ... ...

    Abstract Background: The practice of hand washing is an effective way to prevent contamination and disease transmission. Following the COVID-19 pandemic, hand washing has become increasingly important. Therefore, this qualitative study aimed to understand barriers to hand hygiene compliance among healthcare workers during the COVID-19 pandemic.
    Materials and methods: Twenty-five healthcare workers from intensive care units were sampled using purposive sampling in a qualitative content analysis study. Data were collected through a semi-structured interview and field notes. Based on the Lundman and Graneheim approach, the data were analyzed. COREQ checklist was used to report the research.
    Results: According to the findings, there are three main categories of barriers to hand hygiene practice: barriers related to individuals (including two subcategories of lack of knowledge of healthcare workers and healthcare workers' improper attitude), barriers related to management (including two subcategories of wrong behavioral patterns and unsuitable training and planning), and barriers related to organizations (including four subcategories of heavy workloads, improperly designed wards, a lack of equipment, and lack of quality equipment).
    Conclusions: This research indicates that hand washing practice increased during the COVID-19 pandemic. Nevertheless, some barriers persist, resulting in a decline in hand washing compliance among health care workers. This finding can help managers and policymakers remove barriers to hand washing compliance and improve healthcare workers' adherence to hand washing.
    MeSH term(s) COVID-19/prevention & control ; Guideline Adherence ; Hand Hygiene/methods ; Humans ; Intensive Care Units ; Pandemics
    Language English
    Publishing date 2022-08-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.968231
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Hospital challenges and managerial approaches to combat COVID-19 outbreak: a qualitative study in southeastern Iran.

    Ebrahimi Rigi, Zahra / Namjoo, Zakieh / Jabarpour, Maryam / Ahmadinejad, Mehdi / Ahmadipour, Maryam / Mangolian Shahrbabaki, Parvin / Dehghan, Mahlagha

    BMC health services research

    2023  Volume 23, Issue 1, Page(s) 690

    Abstract: Background: During the covid-19 pandemic, hospitals have faced several challenges, so they need to identify and address effective management strategies to cope with these challenges that enhance their current knowledge to deal with similar challenges in ...

    Abstract Background: During the covid-19 pandemic, hospitals have faced several challenges, so they need to identify and address effective management strategies to cope with these challenges that enhance their current knowledge to deal with similar challenges in the future. This study aimed to identify managerial strategies for dealing with Covid-19 pandemic challenges at a hospital in southeastern Iran.
    Methods: This qualitative content analysis study used purposive sampling to select eight managers, three nurses, and one worker from Shahid Bahonar Hospital. In this study, semi-structured interviews were used to collect data and Lundman and Graneheim's approach was used to analyze them.
    Results: Three hundred fifty codes remained after constant comparison, compression, and merging. The results demonstrated one theme "Managerial reengineering in the healthcare system during the Covid-19 crisis", two main categories, seven subcategories and, 19 sub- subcategories. The first main category was "The difficulty of managing challenges," including "Insufficient resources and physical space", "Socio-organizational challenges" and, "Incompetence and unpreparedness of managers." The second main category was "Reforming the management duties." This category included "Planning and decision-making," "Organization," "Leadership and motivation," and "Monitoring and control."
    Conclusions: Hospitals and managers were less prepared to cope with the Covid-19 crisis challenges due to health system organizations' less attention to biological crises. Healthcare organizations can carefully evaluate these challenges, and the strategies managers adopt to deal with these problems. They also can identify the strategies' strengths and weaknesses and propose more effective strategies. As a result, healthcare organizations will be better prepared for similar crises.
    MeSH term(s) Humans ; COVID-19/epidemiology ; Iran/epidemiology ; Pandemics ; Disease Outbreaks ; Hospitals
    Language English
    Publishing date 2023-06-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050434-2
    ISSN 1472-6963 ; 1472-6963
    ISSN (online) 1472-6963
    ISSN 1472-6963
    DOI 10.1186/s12913-023-09631-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Impact of COVID-19 Outbreak on Nosocomial Infection Rate: A Case of Iran.

    Jabarpour, Maryam / Dehghan, Mahlagha / Afsharipour, Giti / Hajipour Abaee, Elham / Mangolian Shahrbabaki, Parvin / Ahmadinejad, Mehdi / Maazallahi, Mahboobeh

    The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

    2021  Volume 2021, Page(s) 6650920

    Abstract: Background: Coronavirus disease-19 (COVID-19) is a new type of coronavirus that has caused a global pandemic. The disease is highly contagious, and all people are susceptible to the disease. Therefore, extensive measures were taken to prevent the spread ...

    Abstract Background: Coronavirus disease-19 (COVID-19) is a new type of coronavirus that has caused a global pandemic. The disease is highly contagious, and all people are susceptible to the disease. Therefore, extensive measures were taken to prevent the spread of the disease at the community and hospitals. This study aimed to investigate the impact of COVID-19 outbreak on nosocomial infection rate.
    Methods: This cross-sectional study was conducted in an educational hospital, southeast Iran. The nosocomial infection rates of critical/intensive care units (CCU/ICUs) and medical-surgical units were assessed during and before the COVID-19 outbreak.
    Results: There was a 19.75-point decrease in the total rate of nosocomial infection during the COVID-19 outbreak (
    Conclusions: Proper implementation of infection control protocols during the COVID-19 pandemic seems to reduce nosocomial infections.
    Language English
    Publishing date 2021-02-25
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 1057056-1
    ISSN 1712-9532 ; 1180-2332
    ISSN 1712-9532 ; 1180-2332
    DOI 10.1155/2021/6650920
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The impact of dyslipidemia and oxidative stress on vasoactive mediators in patients with renal dysfunction.

    Jabarpour, Maryam / Rashtchizadeh, Nadereh / Argani, Hassan / Ghorbanihaghjo, Amir / Ranjbarzadhag, Masoumeh / Sanajou, Davoud / Panah, Fatemeh / Alirezaei, Amirhesam

    International urology and nephrology

    2019  Volume 51, Issue 12, Page(s) 2235–2242

    Abstract: Hyperlipidemia and oxidative stress are indispensable features of chronic kidney disease (CKD) that favor the development of atherogenic plaques and cardiovascular disease (CVD). A number of vasoactive mediators including proprotein convertase subtilisin- ...

    Abstract Hyperlipidemia and oxidative stress are indispensable features of chronic kidney disease (CKD) that favor the development of atherogenic plaques and cardiovascular disease (CVD). A number of vasoactive mediators including proprotein convertase subtilisin-kexin type 9 (PCSK9), endothelin-1, nitric oxide, and angiotensin II have fundamental roles in the pathophysiology of atherosclerotic events; moreover, their levels are affected by dyslipidemia and oxidative stress due to renal dysfunction. Therefore, therapeutic measures aimed at correcting dyslipidemia and alleviating oxidative stress could potentially protect against CVD in CKD patients. In this review, we discuss the relation between dyslipidemia, oxidative stress, and vasoactive mediators as well as the available treatment options against these disturbances in CKD patients.
    MeSH term(s) Angiotensin II/physiology ; Dyslipidemias/complications ; Dyslipidemias/metabolism ; Endothelin-1/physiology ; Humans ; Nitric Oxide/physiology ; Oxidative Stress ; Proprotein Convertase 9/physiology ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/metabolism
    Chemical Substances Endothelin-1 ; Angiotensin II (11128-99-7) ; Nitric Oxide (31C4KY9ESH) ; PCSK9 protein, human (EC 3.4.21.-) ; Proprotein Convertase 9 (EC 3.4.21.-)
    Language English
    Publishing date 2019-10-22
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 204048-7
    ISSN 1573-2584 ; 0301-1623 ; 0042-1162
    ISSN (online) 1573-2584
    ISSN 0301-1623 ; 0042-1162
    DOI 10.1007/s11255-019-02319-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Protection of renal damage by HMG-CoA inhibitors: A comparative study between atorvastatin and rosuvastatin.

    Jabarpour, Maryam / Rashtchizadeh, Nadereh / Ghorbani Haghjo, Amir / Argani, Hassan / Nemati, Mahboub / Dastmalchi, Siavoush / Roshangar, Leila / Ranjbarzadhag, Masoumeh / Mesgari-Abbasi, Mehran / Bargahi, Nasrin / Sanajou, Davoud

    Iranian journal of basic medical sciences

    2020  Volume 23, Issue 2, Page(s) 206–213

    Abstract: Objectives: Hypercholesterolemia is a common metabolic disorder in developing and developed countries and is associated with the increased rates of chronic kidney disease (CKD). Statin therapy could reduce cholesterol synthesis as well as progression of ...

    Abstract Objectives: Hypercholesterolemia is a common metabolic disorder in developing and developed countries and is associated with the increased rates of chronic kidney disease (CKD). Statin therapy could reduce cholesterol synthesis as well as progression of CKD. Diversity between statins causes variety in pharmacokinetics and pharmacodynamics and also their pleiotropic effects. In the present investigation we aimed to evaluate the protective potentials of both atorvastatin (Ator) (as lipid-soluble statin) and rosuvastatin (Ros) (as water-soluble statin) against renal histopathological damages in the high cholesterol diet induced hypercholesterolemic rats (HCDIHR).
    Materials and methods: Serum lipid profile, oxidized low density lipoprotein (OX-LDL), malondialdehyde (MDA), urea and creatinine levels, as well as renal histopathology were evaluated.
    Results: While Ros acted better than Ator to reduce serum low density lipoprotein cholesterol (LDL-C) (
    Conclusion: The findings underline that the lipophilic Ator may performs better than Ros in attenuating renal damages in HCDIHR.
    Language English
    Publishing date 2020-04-25
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2500485-2
    ISSN 2008-3874 ; 2008-3866
    ISSN (online) 2008-3874
    ISSN 2008-3866
    DOI 10.22038/IJBMS.2019.38239.9080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The effect of oral melatonin on renal ischemia-reperfusion injury in transplant patients: A double-blind, randomized controlled trial.

    Panah, Fatemeh / Ghorbanihaghjo, Amir / Argani, Hassan / Haiaty, Sanya / Rashtchizadeh, Nadereh / Hosseini, Leila / Dastmalchi, Siavoush / Rezaeian, Rostam / Alirezaei, Amirhesam / Jabarpour, Maryam / Nazari Soltan Ahmad, Saeed / Sanajou, Davoud

    Transplant immunology

    2019  Volume 57, Page(s) 101241

    Abstract: Background: One of the important factors in the occurrence of acute kidney injury (AKI) among renal transplant patients (RTPs) is ischemia reperfusion injury (IRI). The current study aimed at determining the anti-inflammatory and anti-oxidative effects ... ...

    Abstract Background: One of the important factors in the occurrence of acute kidney injury (AKI) among renal transplant patients (RTPs) is ischemia reperfusion injury (IRI). The current study aimed at determining the anti-inflammatory and anti-oxidative effects of melatonin on the complications of IRI and the level of Klotho expression in these patients.
    Methods: A total of 40 renal transplant candidates were randomly assigned into placebo or melatonin group receiving the same dose of 3 mg/day. In order to measure serum melatonin levels, inflammatory and oxidative stress factors, renal function biomarkers, and Klotho gene/protein expression, venous blood samples were taken from patients over two different time points, i e, 24 h before the transplantation and at discharge from hospital.
    Results: Melatonin was associated with improvement in renal transplantation, since the serum level of neutrophil gelatinase-associated lipocalin, as a renal functional marker, significantly decreased (P < .001). The effect of melatonin as a suppressor of inflammation and oxidative stress was also evident in the melatonin group due to a significant reduction in the serum levels of MDA, CP, 8-OHdG, and TNF-α markers (P < .001).
    Conclusions: Reduction in serum levels of renal function and oxidative stress/inflammatory markers in the melatonin group indicates that melatonin can inhibit IRI outcomes in RTPs through its anti-oxidant and anti-inflammatory properties. However, these properties do not appear as a result of influence on the level of Klotho gene/protein expression.
    MeSH term(s) 8-Hydroxy-2'-Deoxyguanosine/blood ; Adult ; Anti-Inflammatory Agents/therapeutic use ; Antioxidants/therapeutic use ; Double-Blind Method ; Female ; Gene Expression Regulation/drug effects ; Glucuronidase/genetics ; Glucuronidase/metabolism ; Humans ; Kidney Transplantation ; Lipocalin-2/blood ; Male ; Malondialdehyde/blood ; Melatonin/therapeutic use ; Middle Aged ; Protein Carbonylation ; Reperfusion Injury/prevention & control ; Tumor Necrosis Factor-alpha/blood
    Chemical Substances Anti-Inflammatory Agents ; Antioxidants ; Lipocalin-2 ; Tumor Necrosis Factor-alpha ; Malondialdehyde (4Y8F71G49Q) ; 8-Hydroxy-2'-Deoxyguanosine (88847-89-6) ; Glucuronidase (EC 3.2.1.31) ; klotho protein (EC 3.2.1.31) ; Melatonin (JL5DK93RCL)
    Language English
    Publishing date 2019-08-22
    Publishing country Netherlands
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 1160846-8
    ISSN 1878-5492 ; 0966-3274
    ISSN (online) 1878-5492
    ISSN 0966-3274
    DOI 10.1016/j.trim.2019.101241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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