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  1. Article: Fabrication of Fe(III)-doped mesoporous silica nanoparticles as biocompatible and biodegradable theranostic system for Remdesivir delivery and MRI contrast agent.

    Arkaban, Hasan / Jaberi, Javad / Bahramifar, Ali / Zolfaghari Emameh, Reza / Farnoosh, Gholamreza / Arkaban, Mehdi / Taheri, Ramezan Ali

    Inorganic chemistry communications

    2023  Volume 150, Page(s) 110398

    Abstract: Coronavirus causes the majority of common colds and is spread in the same way that all viruses attack the respiratory system. Despite the trials and efforts to produce a suitable vaccine, there are solutions for the quick, effective and efficient use of ... ...

    Abstract Coronavirus causes the majority of common colds and is spread in the same way that all viruses attack the respiratory system. Despite the trials and efforts to produce a suitable vaccine, there are solutions for the quick, effective and efficient use of existing drugs to prevent infections and improve the condition of patients. In this study, we synthesized mSiO
    Language English
    Publishing date 2023-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2026959-6
    ISSN 1387-7003
    ISSN 1387-7003
    DOI 10.1016/j.inoche.2023.110398
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Management of Brain Cancer and Neurodegenerative Disorders with Polymer-Based Nanoparticles as a Biocompatible Platform.

    Bazi Alahri, Mehdi / Jibril Ibrahim, Alhawarin / Barani, Mahmood / Arkaban, Hassan / Shadman, Seyedeh Malahat / Salarpour, Soodeh / Zarrintaj, Payam / Jaberi, Javad / Turki Jalil, Abduladheem

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 2

    Abstract: The blood-brain barrier (BBB) serves as a protective barrier for the central nervous system (CNS) against drugs that enter the bloodstream. The BBB is a key clinical barrier in the treatment of CNS illnesses because it restricts drug entry into the brain. ...

    Abstract The blood-brain barrier (BBB) serves as a protective barrier for the central nervous system (CNS) against drugs that enter the bloodstream. The BBB is a key clinical barrier in the treatment of CNS illnesses because it restricts drug entry into the brain. To bypass this barrier and release relevant drugs into the brain matrix, nanotechnology-based delivery systems have been developed. Given the unstable nature of NPs, an appropriate amount of a biocompatible polymer coating on NPs is thought to have a key role in reducing cellular cytotoxicity while also boosting stability. Human serum albumin (HSA), poly (lactic-co-glycolic acid) (PLGA), Polylactide (PLA), poly (alkyl cyanoacrylate) (PACA), gelatin, and chitosan are only a few of the significant polymers mentioned. In this review article, we categorized polymer-coated nanoparticles from basic to complex drug delivery systems and discussed their application as novel drug carriers to the brain.
    MeSH term(s) Humans ; Polylactic Acid-Polyglycolic Acid Copolymer ; Polyglycolic Acid ; Lactic Acid ; Drug Delivery Systems ; Drug Carriers ; Brain Neoplasms/drug therapy ; Blood-Brain Barrier ; Nanoparticles ; Neurodegenerative Diseases
    Chemical Substances Polylactic Acid-Polyglycolic Acid Copolymer (1SIA8062RS) ; Polyglycolic Acid (26009-03-0) ; Lactic Acid (33X04XA5AT) ; Drug Carriers
    Language English
    Publishing date 2023-01-14
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28020841
    Database MEDical Literature Analysis and Retrieval System OnLINE

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