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  1. Book ; Thesis: Mikrobewegungsanalyse des zementierten tibialen unikompartimentellen Kniegelenkersatzes

    Jäger, Sebastian

    2014  

    Author's details vorgelegt von Sebastian Jäger
    Language German
    Size 132 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 2014
    HBZ-ID HT018445246
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2014 E 1516 order for loan Magazin

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  2. Book ; Thesis: Isolierung und Charakterisierung von spezifisch an AML1-ETO-positive Leukämiezellen bindenden Peptiden

    Jäger, Sebastian

    2007  

    Author's details vorgelegt von Sebastian Jäger
    Subject code 616.994
    Language German
    Size 81 Bl. : Ill., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Freiburg (Breisgau), Univ., Diss., 2008
    HBZ-ID HT016818502
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2005 MB 71 order for loan Magazin

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  3. Article ; Online: Computer-simulated TOUCH prosthesis cup malposition and solutions.

    Knappe, Kevin / Schonhoff, Mareike / Jaeger, Sebastian / Bickert, Berthold / Harhaus, Leila / Panzram, Benjamin

    Hand surgery & rehabilitation

    2024  , Page(s) 101712

    Abstract: Introduction: Total joint replacement has become significantly more common as a treatment for advanced trapeziometacarpal joint osteoarthritis in recent years. The latest generation of prostheses with dual-mobility designs leads to very good functional ... ...

    Abstract Introduction: Total joint replacement has become significantly more common as a treatment for advanced trapeziometacarpal joint osteoarthritis in recent years. The latest generation of prostheses with dual-mobility designs leads to very good functional results and low rates of loosening and dislocation in the short and medium term. Biomechanical studies showed that central placement and parallel alignment of the cup with respect to the proximal articular surface of the trapezium are crucial for both cup stability and prevention of dislocation. Despite correct positioning of the guidewire, incorrect placement or tilting of the inserted cup may occur, requiring immediate intraoperative revision.
    Methods: The existing spherical and conical cup models in sizes 9 mm and 10 mm were transferred to a computer-aided design dataset. Depending on the intraoperative complication (tilting or incorrect placement), the revision options resulting from the various combinations of cup type and size were simulated and analyzed according to the resulting defect area and bony contact area.
    Results: In well centered cups, a size 9 conical cup could be replaced by a size 9 spherical cup and still be fixed by press-fit. Conversely, a size 9 spherical cup could not be replaced by a size 9 conical cup, but only by a size 10 cup, of whatever shape. When a size 9 conical cup was tilted up to 20°, the best revision option was to resect the sclerotic margin and insert a size 10 conical cup deeper into the cancellous bone, to achieve the largest contact area with the surrounding bone. When a size 9 cup of whatever shape was poorly centered (misplaced with respect to the dorsopalmar or radioulnar line of the trapezium), placement should be corrected using a size 10 cup, combined with autologous bone grafting of the defect. Again, the size 10 conical cup showed the largest bony contact area.
    Conclusion: Our computer-based measurements suggested options for intraoperative cup revision depending on cup shape and size and on type of misalignment with resulting bone defects. These suggestions, however, need to be confirmed in anatomic specimens before introducing them into clinical practice.
    Language English
    Publishing date 2024-05-01
    Publishing country France
    Document type Journal Article
    ZDB-ID 2848776-X
    ISSN 2468-1210
    ISSN (online) 2468-1210
    DOI 10.1016/j.hansur.2024.101712
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1791: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Steryl glucosides recovered from biodiesel tank deposits are an excellent source of phytosterols

    Carlucci, Renzo / Jäger, Sebastián N. / Labadie, Guillermo R.

    Industrial Crops & Products. 2022 Nov., v. 187 p.115307-

    2022  

    Abstract: Over the biodiesel production process some minor components are produced and being accumulated on the storage tanks where precipitate, having a negative impact on the quality of the final product. The identity of the main component of the tank deposits ... ...

    Abstract Over the biodiesel production process some minor components are produced and being accumulated on the storage tanks where precipitate, having a negative impact on the quality of the final product. The identity of the main component of the tank deposits have been unequivocally identified as steryl glucosides (SG). Looking for new repurposed and revalued byproducts from waste of biodiesel production, SG were recognized as potential candidates. Starting from biodiesel tank deposits, a purification procedure was proposed and optimized providing highly pure SG (99%). The procedure allowed the biodiesel recovery, and applied solvents that are commonly used on the vegetable oil and biodiesel factories. Finally, looking to demonstrate the potential of SG as a biorefinery valuable raw material, a process to produce phytosterols was investigated. The proposed circular procedure uses mineral acid and water as reaction media, without extractions with organic solvents. The reaction proved to be very efficient with yields as high as 95%, providing a highly pure raw product (99%). Moreover, the batch process allowed reusing the acidified water at least nine times.
    Keywords batch systems ; biodiesel ; biorefining ; glucosides ; phytosterols ; raw materials ; vegetable oil ; wastes ; Biorefinery ; Steryl glucoside ; Phytosterol
    Language English
    Dates of publication 2022-11
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 1132158-1
    ISSN 1872-633X ; 0926-6690
    ISSN (online) 1872-633X
    ISSN 0926-6690
    DOI 10.1016/j.indcrop.2022.115307
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 5577: Show issues

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  5. Article ; Online: Is taper corrosion in modular revision hip stem junctions associated with patient or implant specific factors? A retrieval analysis.

    Bormann, Therese / Kretzer, J Philippe / Jaeger, Sebastian / Lohmann, Christoph H

    Journal of the mechanical behavior of biomedical materials

    2023  Volume 150, Page(s) 106326

    Abstract: Implant modularity within revision total hip arthroplasty (THA) offers multiple implant configurations and allows surgeons a high intraoperative flexibility to restore functionality to the patients joint, even in complex revision cases. However, a rare ... ...

    Abstract Implant modularity within revision total hip arthroplasty (THA) offers multiple implant configurations and allows surgeons a high intraoperative flexibility to restore functionality to the patients joint, even in complex revision cases. However, a rare but devastating complication for patients, clinicians and manufacturers presenting a breakage of the taper junction between the distal stem and the proximal implant part. Aside from implant and patient specific risk factors, corrosion and fretting at the stem junctions have been associated with taper failure. Whether corrosive processes are a precursor of failure or rather an accompaniment of material fatigue is thereby still unclear. Therefore, this study aims to investigate the incidence of taper corrosion in a collection of 17 retrievals from a single type (MRP-Titan, Peter Brehm GmbH) and on the correlation of taper corrosion to implant and patient specific factors. None of the implants was revised for problems related to the taper junction, corrosion or the implant itself. The modular stem junction of all retrievals was visually rated with respect to corrosion, fretting and surface contamination. Additionally, the stability of taper junctions of retrievals where the proximal part with the neck was still assembled to the stem was determined by measuring the loosening moment of the securing screw and the push-out-force for taper dissociation. There was no difference between the mean push-out-force of the retrievals (14 kN ± 1.2 kN) and new reference samples (12.6 kN ± 0.5 kN). Approximately one third of the investigated retrievals showed considerable taper corrosion. The extent of corrosion increased with time in vivo and contamination of the neck piece, while it decreased with the loosening moment of the locking screw. The parameters femoral head offset, neck piece length, lateralized neck pieces, obesity of patients and septic/aseptic revision were not correlated to taper corrosion. Taper corrosion seems to occur regularly in modular taper junctions and is not necessarily connected to taper failure. A correct assembly of the junction and avoiding taper surface contamination during revision surgery is mandatory.
    MeSH term(s) Humans ; Hip Prosthesis/adverse effects ; Corrosion ; Prosthesis Design ; Arthroplasty, Replacement, Hip ; Reoperation ; Prosthesis Failure
    Language English
    Publishing date 2023-12-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2378381-3
    ISSN 1878-0180 ; 1751-6161
    ISSN (online) 1878-0180
    ISSN 1751-6161
    DOI 10.1016/j.jmbbm.2023.106326
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online: Automated Extraction of Fine-Grained Standardized Product Information from Unstructured Multilingual Web Data

    Flick, Alexander / Jäger, Sebastian / Trajanovska, Ivana / Biessmann, Felix

    2023  

    Abstract: Extracting structured information from unstructured data is one of the key challenges in modern information retrieval applications, including e-commerce. Here, we demonstrate how recent advances in machine learning, combined with a recently published ... ...

    Abstract Extracting structured information from unstructured data is one of the key challenges in modern information retrieval applications, including e-commerce. Here, we demonstrate how recent advances in machine learning, combined with a recently published multilingual data set with standardized fine-grained product category information, enable robust product attribute extraction in challenging transfer learning settings. Our models can reliably predict product attributes across online shops, languages, or both. Furthermore, we show that our models can be used to match product taxonomies between online retailers.

    Comment: ECIR 2023 Demo Track
    Keywords Computer Science - Information Retrieval ; Computer Science - Artificial Intelligence ; Computer Science - Machine Learning
    Publishing date 2023-02-23
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Book: Netzwerk-Design für LKW-Komplettladungsverkehre unter Berücksichtigung ökonomischer und sozialer Aspekte

    Jäger, Sebastian

    (Research)

    2017  

    Institution Springer Fachmedien Wiesbaden GmbH
    Author's details Sebastian Jäger
    Series title Research
    Keywords Arbeitskräftemangel ; Tourenplanung ; Arbeitszeitplan ; Lastkraftwagenfahrer ; Gemischt-ganzzahlige Optimierung ; Standortplanung ; Arbeitszufriedenheit ; Ladungsverkehr ; Lastkraftwagen ; Transportproblem ; Logistikzentrum ; Standortwahl ; Multikriterielle Entscheidungsanalyse ; Heuristik ; Deutschland
    Language German
    Size XXVII, 274 Seiten, Illustrationen, 21 cm x 14.8 cm, 398 g
    Publisher Springer Gabler
    Publishing place Wiesbaden
    Document type Book
    ISBN 3658165855 ; 9783658165857 ; 9783658165864 ; 3658165863
    Database ECONomics Information System

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  8. Conference proceedings: Beurteilung der optimalen Knochenauflage in Korrelation von Röntgen und CT bei einem neuen titanbeschichteten PE Glenoid im humanen Präparat: Was bedeuten Doppellinien und röntgenhelle Linie? Handelt es sich um Lücken?

    Sonntag, Nikolai / Bülhoff, Matthias / Jäger, Sebastian / Kasten, Philip

    2023  , Page(s) AB97–2502

    Event/congress Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2023); Berlin; ; Berufsverband für Orthopädie und Unfallchirurgie; 2023
    Keywords Medizin, Gesundheit ; zementfreies Glenoid ; anatomische Schulterendoprothetik ; zementfreies glenoidales Implantat ; Röntgen-helle Linien zementfreies Glenoid ; CT-Kontrolle zementfreies glenoidales Implantat ; aseptische Prothesenlockerung
    Publishing date 2023-10-23
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/23dkou605
    Database German Medical Science

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  9. Article ; Online: A Benchmark for Data Imputation Methods.

    Jäger, Sebastian / Allhorn, Arndt / Bießmann, Felix

    Frontiers in big data

    2021  Volume 4, Page(s) 693674

    Abstract: With the increasing importance and complexity of data pipelines, data quality became one of the key challenges in modern software applications. The importance of data quality has been recognized beyond the field of data engineering and database ... ...

    Abstract With the increasing importance and complexity of data pipelines, data quality became one of the key challenges in modern software applications. The importance of data quality has been recognized beyond the field of data engineering and database management systems (DBMSs). Also, for machine learning (ML) applications, high data quality standards are crucial to ensure robust predictive performance and responsible usage of automated decision making. One of the most frequent data quality problems is missing values. Incomplete datasets can break data pipelines and can have a devastating impact on downstream ML applications when not detected. While statisticians and, more recently, ML researchers have introduced a variety of approaches to impute missing values, comprehensive benchmarks comparing classical and modern imputation approaches under fair and realistic conditions are underrepresented. Here, we aim to fill this gap. We conduct a comprehensive suite of experiments on a large number of datasets with heterogeneous data and realistic missingness conditions, comparing both novel deep learning approaches and classical ML imputation methods when either only test or train and test data are affected by missing data. Each imputation method is evaluated regarding the imputation quality and the impact imputation has on a downstream ML task. Our results provide valuable insights into the performance of a variety of imputation methods under realistic conditions. We hope that our results help researchers and engineers to guide their data preprocessing method selection for automated data quality improvement.
    Language English
    Publishing date 2021-07-08
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2624-909X
    ISSN (online) 2624-909X
    DOI 10.3389/fdata.2021.693674
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Breakage of Tapered Junctions of Modular Stems in Revision Total Hip Arthroplasty-High Incidence in a Consecutive Series of a Single Institution.

    Bischel, Oliver E / Suda, Arnold J / Böhm, Paul M / Bormann, Therese / Jäger, Sebastian / Seeger, Jörn B

    Bioengineering (Basel, Switzerland)

    2023  Volume 10, Issue 3

    Abstract: Background: Modularity in revision THA (RTHA) has become accepted during the last three decades. Nevertheless, specific risks of modularity of current revision devices such as breakage of taper junctions occur during follow-up. Data reporting failure ... ...

    Abstract Background: Modularity in revision THA (RTHA) has become accepted during the last three decades. Nevertheless, specific risks of modularity of current revision devices such as breakage of taper junctions occur during follow-up. Data reporting failure rates are predominantly given by the manufacturers but independent data acquisition is missing so far.
    Questions/purposes: 1. What time-related risk of breakage of taper junction between neck and body of an established modular revision device can be expected in a consecutive single institutional series and a mid-term follow-up? 2. Are there specific factors influencing breakage in this cohort?
    Materials and methods: A retrospective analysis was performed of a consecutive series of 89 cases after femoral revision using a tapered modular revision stem. Mean follow-up period was 7.1 (range: 3.0-13.7) years. Breakage of stem as failure criteria of the implant was investigated with a Kaplan-Meier analysis.
    Results: Breakage of taper junctions occurred in four patients during follow-up showing a time-depending implant survival of 94.2 (95% CI: 88.6-100%) after 13.7 years. Implant survival of stems with lateralized necks of 87.4 (95% CI: 75.6-100%) after 13.7 years was significantly lower compared to the standard offset variant with 100% after 13.5 years (log rank test
    Conclusions: Cumulative risk for failure of taper junctions was high in this consecutive single institutional cohort and may further increase during follow-up. As independent data acquisition in registries is missing, failure rate may be higher than reported data of the manufacturers. The use of lateralized offset necks in obese patients of at least grade 1 obesity showed a significantly higher risk of breakage. The use of monobloc revision devices may be an option, but randomized control trials are currently missing to establish standardized treatment protocols considering individual risks for both monobloc and/or modular implants.
    Language English
    Publishing date 2023-03-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering10030341
    Database MEDical Literature Analysis and Retrieval System OnLINE

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