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  1. Article ; Online: Vitamin D and Respiratory Diseases : Based on 11th Dr. I. C. Verma Excellence in Research Award for Young Pediatricians Delivered as Oration on 15th Oct. 2023.

    Goyal, Jagdish Prasad

    Indian journal of pediatrics

    2023  Volume 91, Issue 1, Page(s) 67–72

    Abstract: The significance of Vitamin D has been appreciated beyond bone health and calcium metabolism. The importance of Vitamin D in respiratory health has been recognized due to its immunomodulatory and anti-microbial properties. The hypothesis is that Vitamin ... ...

    Abstract The significance of Vitamin D has been appreciated beyond bone health and calcium metabolism. The importance of Vitamin D in respiratory health has been recognized due to its immunomodulatory and anti-microbial properties. The hypothesis is that Vitamin D could have a significant role in the pathogenesis of respiratory diseases and may represent a novel preventive and therapeutic strategy. Furthermore, enumerable observational studies established the association of Vitamin D deficiency with respiratory diseases such as asthma, bronchiolitis, pneumonia, tuberculosis, etc. However, experimental studies have not shown the encouraging results. This brief review will summarize and discuss the synthesis and metabolism of Vitamin D, the prevalence of Vitamin D deficiency in children, its role in the pathogenesis of various childhood respiratory diseases, and an overview of the therapeutic trials assessing the role of Vitamin D supplementation in childhood respiratory diseases.
    MeSH term(s) Child ; Humans ; Vitamin D/therapeutic use ; Respiration Disorders/complications ; Respiration Disorders/drug therapy ; Vitamins/therapeutic use ; Pneumonia/drug therapy ; Vitamin D Deficiency/epidemiology ; Dietary Supplements
    Chemical Substances Vitamin D (1406-16-2) ; Vitamins
    Language English
    Publishing date 2023-11-10
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-023-04904-2
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  2. Article ; Online: Metabolic Syndrome and Childhood Asthma: Association or Causation?

    Goyal, Jagdish Prasad / Prabhakaran, Kalyana

    Indian journal of pediatrics

    2024  Volume 91, Issue 5, Page(s) 425

    MeSH term(s) Humans ; Child ; Metabolic Syndrome/complications ; Asthma/complications
    Language English
    Publishing date 2024-01-13
    Publishing country India
    Document type Editorial
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-023-05018-5
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  3. Article ; Online: Combating Tuberculosis in Malnourished Children: Addressing a Silent Epidemic.

    Rajvanshi, Nikhil / Goyal, Jagdish Prasad

    Indian journal of pediatrics

    2024  

    Language English
    Publishing date 2024-04-26
    Publishing country India
    Document type Editorial
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-024-05136-8
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  4. Article ; Online: Periostin: A Novel Biomarker for Asthma.

    Goyal, Jagdish Prasad / Rajvanshi, Nikhil

    Indian journal of pediatrics

    2023  Volume 90, Issue 5, Page(s) 427–428

    MeSH term(s) Humans ; Asthma/diagnosis ; Biomarkers ; Cell Adhesion Molecules/metabolism
    Chemical Substances Biomarkers ; Cell Adhesion Molecules
    Language English
    Publishing date 2023-03-08
    Publishing country India
    Document type Editorial ; Comment
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-023-04511-1
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  5. Article ; Online: In Reply: Olanzapine for Chemotherapy-induced Nausea and Vomiting Pediatric Population: Take Home Message?

    Meena, Jagdish Prasad / Gupta, Aditya Kumar / Jat, Kana Ram

    Journal of pediatric hematology/oncology

    2024  Volume 46, Issue 4, Page(s) 216

    MeSH term(s) Humans ; Olanzapine/therapeutic use ; Olanzapine/adverse effects ; Vomiting/chemically induced ; Vomiting/drug therapy ; Nausea/chemically induced ; Nausea/drug therapy ; Child ; Antiemetics/therapeutic use ; Antineoplastic Agents/adverse effects ; Neoplasms/drug therapy
    Chemical Substances Olanzapine (N7U69T4SZR) ; Antiemetics ; Antineoplastic Agents
    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Letter ; Journal Article
    ZDB-ID 1231152-2
    ISSN 1536-3678 ; 1077-4114 ; 0192-8562
    ISSN (online) 1536-3678
    ISSN 1077-4114 ; 0192-8562
    DOI 10.1097/MPH.0000000000002845
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Orbital Emphysema with Subcutaneous Emphysema: An Unusual Presentation of Common Cause.

    Prabhakaran, Kalyana / Uppaluri, Pradeep Babu / Goyal, Jagdish Prasad / Kumar, Prawin

    Indian journal of pediatrics

    2024  

    Language English
    Publishing date 2024-02-01
    Publishing country India
    Document type Journal Article
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-024-05029-w
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  7. Article ; Online: Lipodystrophy following diphtheria, pertussis and tetanus (DPT) vaccine.

    Prabhakaran, Kalyana / Agarwal, Saurabh / Goyal, Jagdish Prasad / Kumar, Prawin

    BMJ case reports

    2024  Volume 17, Issue 3

    MeSH term(s) Humans ; Tetanus Toxoid ; Diphtheria ; Whooping Cough ; Tetanus ; Corynebacterium ; Lipodystrophy
    Chemical Substances Tetanus Toxoid
    Language English
    Publishing date 2024-03-04
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2023-259514
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  8. Article: Utility of systemic immune-inflammation Index as a serum biomarker to differentiate between complicated and simple para-pneumonic effusion.

    Rajvanshi, Nikhil / Kumar, Prawin / Goyal, Jagdish Prasad

    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace

    2023  

    Abstract: The systemic immune-inflammation index (SII) is a novel inflammatory biomarker. Simple and complicated para-pneumonic effusion (PPE) are two significant complications of pneumonia. We evaluated the efficacy of the systemic immune inflammation index (SII) ...

    Abstract The systemic immune-inflammation index (SII) is a novel inflammatory biomarker. Simple and complicated para-pneumonic effusion (PPE) are two significant complications of pneumonia. We evaluated the efficacy of the systemic immune inflammation index (SII) to differentiate between the two. Records of all children up to 18 years of age admitted between April 2019 and September 2022 and diagnosed with Simple or complicated PPE were retrospectively evaluated. SII and other biomarkers were compared between both groups. ROC with the Youden index was used to estimate the discriminative value of SII. Fifty children were enrolled with a median (IQR) age of 81.5 (36.7, 133.5) months; 31 (62%) were male. Thirty-one (62%) had complicated PPE, and 19 (38%) had simple PPE. SII was significantly higher in complicated PPE (p=0.007). Good areas under the curve (AUCs) were found for CRP (0.771) and SII (0.736) to differentiate complicated from simple PPE. The best cut-off value for SII to differentiate complicated PPE from simple PPE was 1557×103µL, with a sensitivity of 82.4% and specificity of 57.6%. SII can be used as a screening tool to differentiate between complicated and simple PPE at the time of presentation.
    Language English
    Publishing date 2023-09-07
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1160940-0
    ISSN 1122-0643 ; 1120-0391
    ISSN 1122-0643 ; 1120-0391
    DOI 10.4081/monaldi.2023.2652
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  9. Article ; Online: Evaluation of Chronic Cough in Children Using Management Algorithm: A Prospective Cohort Study.

    Rajvanshi, Nikhil / Kumar, Prawin / Goyal, Jagdish Prasad

    Indian journal of pediatrics

    2023  Volume 91, Issue 4, Page(s) 337–343

    Abstract: Objective: To assess the use of a standardized evaluation algorithm [American College of Chest Physician (ACCP) 2006] in children with chronic cough.: Methods: In this prospective cohort study, children with chronic cough were evaluated as per the ... ...

    Abstract Objective: To assess the use of a standardized evaluation algorithm [American College of Chest Physician (ACCP) 2006] in children with chronic cough.
    Methods: In this prospective cohort study, children with chronic cough were evaluated as per the ACCP 2006 diagnostic algorithm. All children were followed regularly at an interval of 2-4 wk. The study's endpoint was for the patient being cough free for four weeks either following treatment or naturally.
    Results: The mean age of the 87 studied children (52 male, 35 female) was 11.9±3 y. Forty children (45.9%) had specific cough pointers on history and examination. Radiograph showed abnormalities in 12 (13.8%) children, and spirometry showed a reversible obstructive pattern on spirometry in 6 (6.9%) among 47 (54%) children without specific cough pointers. After a detailed evaluation, 16 (18.3%) children had no remarkable findings and were reviewed after two weeks. Spontaneous resolution of cough occurred in 6 children. A trial of inhalational corticosteroids (ICS) (9 children) or antibiotics (1 child) was given to the rest of the ten children. Specific underlying diagnoses could be established in 80 (91.9%) children. The most common etiology identified in the study was asthma and asthma-like illnesses (n = 52; 59.8%), followed by upper airway cough syndrome (n = 13; 14.9%) and tuberculosis (n = 9; 10.4%). Eighty-four (96.5%) children had complete resolution of cough during follow-up. The mean time to resolution in the study was 33.6±16.8 d.
    Conclusions: This study demonstrated that the ACCP 2006 algorithm is effective in establishing the underlying etiology and managing children with chronic cough.
    MeSH term(s) Child ; Humans ; Male ; Female ; Chronic Cough ; Prospective Studies ; Cough/etiology ; Asthma/complications ; Algorithms ; Chronic Disease ; Respiratory System Abnormalities
    Language English
    Publishing date 2023-06-08
    Publishing country India
    Document type Journal Article
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-023-04632-7
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  10. Article ; Online: Shorter Duration of Antibiotics in Low-Risk Febrile Neutropenia in Children with Malignancy.

    Meena, Jagdish Prasad / Gupta, Aditya Kumar

    Indian journal of pediatrics

    2021  Volume 88, Issue 3, Page(s) 217–218

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Child ; Febrile Neutropenia/drug therapy ; Humans ; Neoplasms/complications ; Neoplasms/drug therapy
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-01-07
    Publishing country India
    Document type Editorial ; Comment
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-020-03654-9
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