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Article ; Online: Transmittance thresholds of electrochromic glazing to achieve annual low-glare work environments

Wienold Jan / Jain Sneha / Andersen Marilyne

E3S Web of Conferences, Vol 362, p

2022 Volume 08001

Abstract: A recent study on the glare protection performance of electrochromic (EC) glazing showed that visible transmittance levels lower than 0.6% are necessary to achieve comfortable situations for sun positions, that were close to the central field of view. ... ...

Abstract	A recent study on the glare protection performance of electrochromic (EC) glazing showed that visible transmittance levels lower than 0.6% are necessary to achieve comfortable situations for sun positions, that were close to the central field of view. However, the question that arises is how often such situations occur throughout the year and how the glare protection performance of EC systems is for typical office situations for different climates and orientations. This study aims to quantify the annual performance for such configurations by applying improved simulation methods to conduct annual glare simulations and comparing them to the EN17037 classifications. The enhancement of the simulation method compared to existing methods was necessary to correctly consider the blurring effect in the lens of the eye – neglecting this would lead to an overestimation of glare. We found that for mid and north European climates the extreme situations do not occur such often, so that the ECglazing systems being able to switch to transmittance levels of 1% can mitigate glare throughout the year reasonably well for typical office situations and reaches typically the highest glare protection category according to EN17037 for a viewing direction, that is parallel to the facade. For more sunny climates such as Rome, slightly lower transmittance levels (around 0.5%) would be necessary to achieve a similar glare protection level. The study also revealed that tables E.7 and E.8 of EN17037 with pre-calculated 95-percentile Daylight Glare Probability (DGP) values should be re-calculated.
Keywords	Environmental sciences ; GE1-350
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
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Article: Knowledge, attitude, and practice on digital eye strain during coronavirus disease-2019 lockdown: A comparative study.

Jain, Sneha / Das, Oindrila / Roy, Aindrila / Das, Abhisekh

Oman journal of ophthalmology

2022 Volume 15, Issue 3, Page(s) 279–283

Abstract: Background: Computer vision syndrome is a group of eye and vision-related problems that result from prolonged computer use. The worldwide pandemic of coronavirus disease-2019 (COVID-19) lockdown has led to an increase in the digital screen exposure as ... ...

Abstract	Background: Computer vision syndrome is a group of eye and vision-related problems that result from prolonged computer use. The worldwide pandemic of coronavirus disease-2019 (COVID-19) lockdown has led to an increase in the digital screen exposure as jobs as well as academic learning have majorly shifted online. This has caused an increase in digital eye strain (DES) globally. The aims and objectives of this study were to compare the knowledge, attitude, and practices among medical and nonmedical professionals with regard to DES in a background of COVID-19 lockdown. Materials and methods: A cross-sectional, observational, online questionnaire-based research survey analysis was conducted among medical professionals with age- and sex-matched nonmedical professionals. Responses were collected over a week and analyzed. The level of significance was set at a Results: Our study included 353 (50.4%) medical and 347 (49.6%) nonmedical personnel. It was noted that 266 (75.4%) of medical professionals and 268 (77.2%) of nonmedical professionals experienced eye problems after prolonged digital screen exposure. A significant proportion of respondents experienced an increase in symptoms following COVID-19 lockdown with 140 (52.6%) being medical professionals and 163 (60.8%) nonmedical professionals ( Conclusions: DES is a preventable lifestyle-associated disorder. Awareness among the masses can reduce the adverse effects. Proper lighting, adequate viewing distance, voluntary blinking, and using lubricating eye drops are a few ways to reduce the chances of DES. Further studies are needed to formulate standardized guidelines for the management of DES.
Language	English
Publishing date	2022-11-02
Publishing country	India
Document type	Journal Article
ZDB-ID	2484272-2
ISSN	0974-7842 ; 0974-620X
ISSN (online)	0974-7842
ISSN	0974-620X
DOI	10.4103/ojo.ojo_135_21
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Article: Use of cribriform amplatzer septal occluder in the pediatric population: Feasibility, safety, and technical considerations.

Pradhan, Priya / Jain, Sneha / Sen, Supratim / Dalvi, Bharat

Annals of pediatric cardiology

2021 Volume 14, Issue 2, Page(s) 159–164

Abstract: Purpose: Fenestrated atrial septal defects (F-ASDs) in the pediatric population pose a challenge for transcatheter device closure since multiple devices are not preferred in small hearts. Oversizing the Amplatzer Septal Occluder (ASO) to cover the ... ...

Abstract	Purpose: Fenestrated atrial septal defects (F-ASDs) in the pediatric population pose a challenge for transcatheter device closure since multiple devices are not preferred in small hearts. Oversizing the Amplatzer Septal Occluder (ASO) to cover the surrounding fenestrations usually distorts the central waist as well as the disc profile and often defeats the purpose. This is a retrospective observational study with an aim to assess the feasibility and safety of cribriform ASO in closing F-ASDs in small children. Methods: Sixteen children with F-ASD who underwent device closure with cribriform ASO were included in the study. The fenestrated septal length (FSL) and the total septal length (TSL) were measured on transesophageal echocardiogram. A device size which was 1.5-2 times the FSL but smaller than the TSL was selected. The defect was closed with a device passed through a relatively centrally placed smaller fenestration. Results: The median age of the cohort was 5 years (2.5-10.5). Majority (14/16) required 25 or 30 mm cribriform ASO. Aneurysmal interatrial septum was seen in most of our patients (11/15). All the patients had successful device implantation. Complete closure of the defect was seen in 11 patients while 5 patients had insignificant residual shunt at a median follow-up of 40 months (1-60 months). There were no other complications. Conclusions: Cribriform ASO can be used safely and effectively in closing F-ASDs in children. Deployment of the device through a small central hole allows covering maximum fenestrations and gives more stability to the device. Residual shunts, although not infrequent, are insignificant.
Language	English
Publishing date	2021-04-10
Publishing country	India
Document type	Journal Article
ZDB-ID	2430956-4
ISSN	0974-5149 ; 0974-2069
ISSN (online)	0974-5149
ISSN	0974-2069
DOI	10.4103/apc.APC_69_20
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Article ; Online: Contemporary attitudes and beliefs on coronary artery calcium from social media using artificial intelligence.

Somani, Sulaiman / Balla, Sujana / Peng, Allison W / Dudum, Ramzi / Jain, Sneha / Nasir, Khurram / Maron, David J / Hernandez-Boussard, Tina / Rodriguez, Fatima

NPJ digital medicine

2024 Volume 7, Issue 1, Page(s) 83

Abstract: Coronary artery calcium (CAC) is a powerful tool to refine atherosclerotic cardiovascular disease (ASCVD) risk assessment. Despite its growing interest, contemporary public attitudes around CAC are not well-described in literature and have important ... ...

Abstract	Coronary artery calcium (CAC) is a powerful tool to refine atherosclerotic cardiovascular disease (ASCVD) risk assessment. Despite its growing interest, contemporary public attitudes around CAC are not well-described in literature and have important implications for shared decision-making around cardiovascular prevention. We used an artificial intelligence (AI) pipeline consisting of a semi-supervised natural language processing model and unsupervised machine learning techniques to analyze 5,606 CAC-related discussions on Reddit. A total of 91 discussion topics were identified and were classified into 14 overarching thematic groups. These included the strong impact of CAC on therapeutic decision-making, ongoing non-evidence-based use of CAC testing, and the patient perceived downsides of CAC testing (e.g., radiation risk). Sentiment analysis also revealed that most discussions had a neutral (49.5%) or negative (48.4%) sentiment. The results of this study demonstrate the potential of an AI-based approach to analyze large, publicly available social media data to generate insights into public perceptions about CAC, which may help guide strategies to improve shared decision-making around ASCVD management and public health interventions.
Language	English
Publishing date	2024-03-30
Publishing country	England
Document type	Journal Article
ISSN	2398-6352
ISSN (online)	2398-6352
DOI	10.1038/s41746-024-01077-w
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Article ; Online: The S-S bridge mutation between the A2 and A4 loops (T416C-I432C) of Cel7A of

Dodda, Subba Reddy / Hossain, Musaddique / Mondal, Sudipa / Das, Shalini / Khator Jain, Sneha / Aikat, Kaustav / Mukhopadhyay, Sudit S

Applied and environmental microbiology

2024 Volume 90, Issue 4, Page(s) e0232923

Abstract: Disulfide bonds are important for maintaining the structural conformation and stability of the protein. The introduction of the disulfide bond is a promising strategy to increase the thermostability of the protein. In this report, cysteine residues are ... ...

Abstract	Disulfide bonds are important for maintaining the structural conformation and stability of the protein. The introduction of the disulfide bond is a promising strategy to increase the thermostability of the protein. In this report, cysteine residues are introduced to form disulfide bonds in the Glycoside Hydrolase family GH 7 cellobiohydrolase (GH7 CBHs) or Cel7A of
MeSH term(s)	Aspergillus fumigatus/genetics ; Aspergillus fumigatus/metabolism ; Cellulose 1,4-beta-Cellobiosidase/genetics ; Cellulose 1,4-beta-Cellobiosidase/metabolism ; Cysteine ; Mutation ; Disulfides ; Enzyme Stability
Chemical Substances	Cellulose 1,4-beta-Cellobiosidase (EC 3.2.1.91) ; Cysteine (K848JZ4886) ; Disulfides
Language	English
Publishing date	2024-03-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	223011-2
ISSN	1098-5336 ; 0099-2240
ISSN (online)	1098-5336
ISSN	0099-2240
DOI	10.1128/aem.02329-23
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Article ; Online: Influence of macular pigment on the sensitivity to discomfort glare from daylight.

Jain, Sneha / Wienold, Jan / Eandi, Chiara / Gisselbaek, Sara / Kawasaki, Aki / Andersen, Marilyne

Scientific reports

2023 Volume 13, Issue 1, Page(s) 18551

Abstract: Understanding the factors that influence the human perception of glare is necessary to properly address glare risks in buildings and achieve comfortable visual environments, especially in the workplace. Yet large inter-individual variabilities in glare ... ...

Abstract	Understanding the factors that influence the human perception of glare is necessary to properly address glare risks in buildings and achieve comfortable visual environments, especially in the workplace. Yet large inter-individual variabilities in glare perception remain unexplained and thus uncovered by the current empirical glare models. We hypothesize that this variability has an origin in the human retina, in particular in the density of macular pigments present in its central area, which varies between individuals. Macular pigments are known to absorb blue light and attenuate chromatic aberration, thus reducing light scatter. This study presents the outcomes of the first experiment ever conducted in a daylit office environment, in which glare sensitivity and macular pigment density were measured and compared for 110 young healthy individuals, along with other ocular parameters. The participants were exposed to different glare conditions induced by the sun filtered through either color-neutral or blue-colored glazing. In neutral daylight conditions with sun disc in the near periphery, neither macular pigment nor any other investigated ocular factors have an impact on discomfort glare perception whereas glare perception in conditions with the blue-colored sun disc in the near periphery was found to be correlated with macular pigment optical density.
MeSH term(s)	Humans ; Glare ; Macular Pigment ; Macula Lutea ; Retinal Pigments ; Light ; Contrast Sensitivity
Chemical Substances	Macular Pigment ; Retinal Pigments
Language	English
Publishing date	2023-10-29
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-45785-x
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Article ; Online: Letter to the Editor on "Midterm Results of a Contemporary, Porous-Coated Acetabular System in Patients Undergoing Primary Total Hip Replacement for Degenerative Hip Disease: A Prospective, Multicenter Study".

Ow, Zachariah Gene Wing / Jain, Sneha Rajiv / Ng, Cheng Han

The Journal of arthroplasty

2020 Volume 35, Issue 11, Page(s) 3423–3424

MeSH term(s)	Acetabulum/surgery ; Arthroplasty, Replacement, Hip/adverse effects ; Hip Prosthesis ; Humans ; Porosity ; Prospective Studies
Language	English
Publishing date	2020-08-06
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	632770-9
ISSN	1532-8406 ; 0883-5403
ISSN (online)	1532-8406
ISSN	0883-5403
DOI	10.1016/j.arth.2020.07.079
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Article ; Online: Hybrid stenting of the arterial duct with carotid cutdown and flip technique: immediate and early results.

Sen, Supratim / Pradhan, Priya / Jain, Sneha / Trivedi, Dipesh / Kaushik, Pradeep

Cardiology in the young

2021 Volume 32, Issue 8, Page(s) 1254–1260

Abstract: Stenting of the arterial duct (PDA) has become a standard palliation for ductal-dependent pulmonary circulation. Carotid arterial access provides a direct route for stenting vertical ducts. We evaluated our early results of hybrid ductal stenting via ... ...

Abstract	Stenting of the arterial duct (PDA) has become a standard palliation for ductal-dependent pulmonary circulation. Carotid arterial access provides a direct route for stenting vertical ducts. We evaluated our early results of hybrid ductal stenting via surgical carotid cutdown. Methods and results: In this retrospective single centre cohort study, hybrid PDA stenting was attempted in 11 patients with "flip technique", between January 2020 and February 2021, and was successful in 10. Median age was 29 days (interquartile range 17.5-87) and mean weight 3.37 ± 1.23 kg. Mean fluoroscopy time was 13.58 ± 5.35 minutes, mean procedure time was 48.50 ± 22.5 minutes, and mean radiation dose was 1719.5 ± 1217.6 mGycm Conclusion: This study adds to the limited literature on ductal stenting with carotid access and the flip technique. In our early experience, the hybrid carotid approach is an attractive alternative to percutaneous carotid puncture and has simplified a complex and challenging intervention, with good outcomes.
MeSH term(s)	Adult ; Cohort Studies ; Ductus Arteriosus ; Ductus Arteriosus, Patent/surgery ; Humans ; Retrospective Studies ; Stents ; Treatment Outcome
Language	English
Publishing date	2021-10-11
Publishing country	England
Document type	Journal Article
ZDB-ID	1078466-4
ISSN	1467-1107 ; 1047-9511
ISSN (online)	1467-1107
ISSN	1047-9511
DOI	10.1017/S1047951121004017
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Article ; Online: Treatment effect of canagliflozin for patients on therapy for heart failure: Pooled analysis of the CANVAS program and CREDENCE trial.

Jain, Sneha S / Yu, Jie / Arnott, Clare / Neal, Bruce / Perkovic, Vlado / Neuen, Brendon L / Jardine, Meg / Mahaffey, Kenneth W

International journal of cardiology

2023 Volume 395, Page(s) 131444

Abstract: Background: Canagliflozin is a sodium-glucose cotransporter 2 inhibitor that has been shown to reduce cardiovascular events in diabetic patients with and without heart failure (HF). Whether the clinical benefits and safety profile of canagliflozin are ... ...

Abstract	Background: Canagliflozin is a sodium-glucose cotransporter 2 inhibitor that has been shown to reduce cardiovascular events in diabetic patients with and without heart failure (HF). Whether the clinical benefits and safety profile of canagliflozin are different in those on a beta blocker and an angiotensin-converting enzyme inhibitor/angiotensin receptor blocker (BB + RAASi) is unknown. Methods: We pooled participants with HF at baseline from the CANVAS Program and CREDENCE trial and assessed major adverse cardiovascular events and its components; hospitalization for heart failure (HHF); HHF or CV death; all-cause mortality; a renal composite; and a combined renal and CV composite. Results: Of 14,543 participants, 2113 had HF at baseline, and 1280 were on BB + RAASi. In those with a history of HF, participants on BB + RAASi therapy were more likely to have coronary atherosclerotic disease (82 vs 72%, p < 0.001), history of myocardial infarction (42 vs 29%, p < 0.001), higher mean body mass index (34 vs 32 kg/m Conclusion: Canagliflozin mostly improved CV and kidney outcomes in participants with a history of HF irrespective of use of BB + RAASi at baseline, with possible greater benefit on HHF/CV death in participants on BB + RAASi.
MeSH term(s)	Humans ; Canagliflozin/therapeutic use ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/epidemiology ; Cardiovascular Diseases ; Heart Failure/diagnosis ; Heart Failure/drug therapy ; Heart Failure/chemically induced ; Myocardial Infarction/drug therapy
Chemical Substances	Canagliflozin (0SAC974Z85) ; Sodium-Glucose Transporter 2 Inhibitors
Language	English
Publishing date	2023-10-14
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2023.131444
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Article: Response to the comments on "A Prospective Observational Study on Changes in Intraocular Pressure and Iridocorneal Angle Following the Use of Escitalopram and Amitriptyline".

Mandal, Shaswata / Acharya, Rudraprasad / Mallik, Nitu / Jain, Sneha / Ghosh, Asim Kumar / Ghosal, Malay Kumar / Pal, Arghya

Indian journal of psychological medicine

2023 Volume 45, Issue 3, Page(s) 324–325

Language	English
Publishing date	2023-04-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	2622378-8
ISSN	0975-1564 ; 0253-7176
ISSN (online)	0975-1564
ISSN	0253-7176
DOI	10.1177/02537176231164752
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