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  1. Article ; Online: PROPHYLACTIC ANTIBIOTICS DURING THE IMPLANT PROSTHETIC PHASE MAY NOT SUBSTANTIALLY DECREASE THE INCIDENCE OF INFECTIOUS COMPLICATIONS.

    Lazic, Marko / Jakovljevic, Aleksandar / Valente, Nicola Alberto

    The journal of evidence-based dental practice

    2023  Volume 24, Issue 1, Page(s) 101963

    Abstract: Article title and bibliographic information: Does the Prosthetic Phase of Dental Implants Justify the Prescription of Preventive Antibiotics in Healthy Patients? A Systematic Review. Salgado-Peralvo AO, Uribarri A, Peña-Cardelles JF, Kewalramani N, ... ...

    Abstract Article title and bibliographic information: Does the Prosthetic Phase of Dental Implants Justify the Prescription of Preventive Antibiotics in Healthy Patients? A Systematic Review. Salgado-Peralvo AO, Uribarri A, Peña-Cardelles JF, Kewalramani N, Rodríguez JLG, Velasco-Ortega E. J Oral Implantol. 2023 Feb 1;49(1):93-101.
    Source of funding: The authors declared that no funding was received to support the study.
    Type of study/design: Systematic review.
    MeSH term(s) Humans ; Anti-Bacterial Agents/therapeutic use ; Incidence ; Systematic Reviews as Topic
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-12-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2056058-8
    ISSN 1532-3390 ; 1532-3382
    ISSN (online) 1532-3390
    ISSN 1532-3382
    DOI 10.1016/j.jebdp.2023.101963
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  2. Article ; Online: LIMITED EVIDENCE SHOWS A HIGH GLOBAL BURDEN OF APICAL PERIODONTITIS AMONG ADULTS WORLDWIDE.

    Jakovljevic, Aleksandar / Aminoshariae, Anita

    The journal of evidence-based dental practice

    2021  Volume 22, Issue 1, Page(s) 101667

    Abstract: Article title and bibliographic information: Tibúrcio-Machado CS, Michelon C, Zanatta FB, Gomes MS, Marin JA, Bier CA. The global prevalence of apical periodontitis: a systematic review and meta-analysis. Int Endod J. 2021;54(5):712-735.: Source of ... ...

    Abstract Article title and bibliographic information: Tibúrcio-Machado CS, Michelon C, Zanatta FB, Gomes MS, Marin JA, Bier CA. The global prevalence of apical periodontitis: a systematic review and meta-analysis. Int Endod J. 2021;54(5):712-735.
    Source of funding: Information not available.
    Type of study/design: Systematic review with meta-analysis.
    MeSH term(s) Adult ; Humans ; Periapical Periodontitis/epidemiology ; Prevalence
    Language English
    Publishing date 2021-11-27
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2056058-8
    ISSN 1532-3390 ; 1532-3382
    ISSN (online) 1532-3390
    ISSN 1532-3382
    DOI 10.1016/j.jebdp.2021.101667
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  3. Article ; Online: ENDODONTIC PERIAPICAL LESIONS ARE CHARACTERIZED WITH THE HIGH PREVALENCE OF VIABLE AND ACTIVEMICROORGANISMS.

    Jakovljevic, Aleksandar / Ivanovic, Katarina Beljic

    The journal of evidence-based dental practice

    2021  Volume 21, Issue 4, Page(s) 101636

    Abstract: Article title and bibliographic information: Bronzato JD, Bomfim RA, Hayasida GZP, Cúri M, Estrela C, Paster BJ, Gomes BPFA. Analysis of microorganisms in periapical lesions: A systematic review and meta-analysis. Arch Oral Biol. 2021;124:105055. doi:10. ...

    Abstract Article title and bibliographic information: Bronzato JD, Bomfim RA, Hayasida GZP, Cúri M, Estrela C, Paster BJ, Gomes BPFA. Analysis of microorganisms in periapical lesions: A systematic review and meta-analysis. Arch Oral Biol. 2021;124:105055. doi:10.1016/j.archoralbio.2021.105055. Epub 2021 Feb 12.
    Source of funding: Supported by the Brazilian agencies São Paulo Research Foundation (FAPESP) under grant no. 2015/23,479-5; National Scientific and Technological Development Council (CNPq) under grants no 308,162/2014-5 and 303,852/2019-4; and Coordination for Improvement of Higher Education Personnel (CAPES) Finance Code 001; grants no 88,887.369163/2019-00 and 88,887.342794/2019-00..
    Type of study/design: Systematic review with meta-analysis of data.
    MeSH term(s) Brazil ; Humans ; Prevalence
    Language English
    Publishing date 2021-09-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2056058-8
    ISSN 1532-3390 ; 1532-3382
    ISSN (online) 1532-3390
    ISSN 1532-3382
    DOI 10.1016/j.jebdp.2021.101636
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  4. Article ; Online: Periodontal health status in systemic sclerosis patients: Systematic review and meta-analysis.

    Sredojevic, Stefan / Colak, Dejana / Gaspersic, Rok / Pavlov Dolijanovic, Slavica / Jakovljevic, Aleksandar / Nikolic-Jakoba, Natasa

    PloS one

    2024  Volume 19, Issue 2, Page(s) e0291078

    Abstract: Objective: The present systematic review and meta-analysis aimed to evaluate the periodontal health of systemic sclerosis patients compared with non-systemic sclerosis controls.: Materials and methods: Online databases were searched for eligible ... ...

    Abstract Objective: The present systematic review and meta-analysis aimed to evaluate the periodontal health of systemic sclerosis patients compared with non-systemic sclerosis controls.
    Materials and methods: Online databases were searched for eligible studies on February 24, 2023. The primary outcomes of interest in systemic sclerosis patients and controls included the clinical attachment level, periodontal probing depth, recession depth, plaque index, bleeding on probing score, gingival index, number of teeth with periodontitis, prevalence of periodontitis and gingivitis, and extent and severity of periodontitis.
    Results: Fourteen studies met inclusion criteria and were incorporated in the qualitative and quantitative analysis. In comparison with the controls, systemic sclerosis patients had a higher prevalence of periodontitis (OR = 7.63 (1.74-33.50), p = 0.04, I2 = 69%), including more severe forms of periodontitis (OR = 6.68 (3.39-13.15), p = 0.85, I2 = 0%), as well as higher periodontal probing depth ((0.88 (0.45-1.31), p = 0.02, I2 = 99%)), clinical attachment level (1.22 (0.8-1.64), p = 0.003, I2 = 98%), and plaque presence (0.83 (0.13-1.53), p = 0.03, I2 = 96%). There was no statistically significant difference in gingival inflammation (1.14 (0.07-2.21), p = 0.04, I2 = 98%).
    Conclusions: The systematic review and the meta-analysis showed that systemic sclerosis patients suffer from worse periodontal health than non-systemic sclerosis individuals.
    MeSH term(s) Humans ; Periodontitis/complications ; Periodontitis/epidemiology ; Gingivitis/complications ; Gingivitis/epidemiology ; Periodontal Index ; Prevalence ; Periodontal Attachment Loss
    Language English
    Publishing date 2024-02-02
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0291078
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  5. Article ; Online: Effectiveness of vital pulp treatment in managing nontraumatic pulpitis associated with no or nonspontaneous pain: A systematic review.

    Jakovljevic, Aleksandar / Jaćimović, Jelena / Aminoshariae, Anita / Fransson, Helena

    International endodontic journal

    2022  Volume 56 Suppl 3, Page(s) 340–354

    Abstract: Background: The exposed pulp has been the topic of numerous studies, but well-designed and well-executed comparative trials on the outcome and treatment of these teeth have been limited.: Objectives: This study was conducted to answer the following ... ...

    Abstract Background: The exposed pulp has been the topic of numerous studies, but well-designed and well-executed comparative trials on the outcome and treatment of these teeth have been limited.
    Objectives: This study was conducted to answer the following questions: in patients with nontraumatic pulpitis associated with no or nonspontaneous pain in permanent teeth, (i) is direct pulp capping or pulpotomy (partial/full) as effective as selective or stepwise caries removal [Population/participants, Intervention(s), Comparator(s)/control, Outcome(s) (PICO) 1], (ii) is pulpotomy (partial/full) as effective as direct pulp capping (PICO 2) and (iii) is pulpotomy (partial/full) as effective as a pulpectomy (PICO 3), in terms of a combination of patient and clinical reported outcomes, with 'tooth survival' as the most critical outcome?
    Methods: A literature search was conducted using Clarivate Analytics' Web of Science, Scopus, PubMed and Cochrane Central Register of Controlled Trials from inception to November 3rd 2021. Grey literature and contents of the major subject journals were examined. Eligibility criteria followed the PICO questions. Two independent reviewers performed study selection, data extraction and appraisal; disagreements were resolved by a third reviewer. The risk of bias was assessed by the revised Cochrane risk-of-bias tool for randomized trials.
    Results: Three randomized clinical trials (RCTs) were included in the review. No study fulfilled the criteria to answer PICO 1. There were no significant differences in the reported outcomes between investigated treatments in all included RCTs. None of the included studies reported the most critical outcome 'tooth survival'. A high loss of patients during the follow-up period was observed.
    Discussion: Although a few studies fulfilled strict eligible criteria, the results of this systematic review clearly highlight a paucity of available evidence. At the present time, clinical decisions cannot be substantiated by direct comparative trials.
    Conclusions: Based on limited evidence, this systematic review discovered no significant differences in effectiveness between compared vital pulp treatments in managing nontraumatic pulpitis associated with no or nonspontaneous pain. Further high-quality RCTs are necessary to investigate the effectiveness of direct pulp capping or pulpotomy (partial/full) compared to selective or stepwise caries removal.
    Registration: PROSPERO database (CRD42021259742).
    MeSH term(s) Humans ; Pulpitis/therapy ; Dental Caries/therapy ; Dental Pulp ; Pulpotomy/methods ; Root Canal Therapy ; Dental Pulp Capping/methods ; Treatment Outcome
    Language English
    Publishing date 2022-05-25
    Publishing country England
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 603734-3
    ISSN 1365-2591 ; 0143-2885
    ISSN (online) 1365-2591
    ISSN 0143-2885
    DOI 10.1111/iej.13776
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  6. Article ; Online: Herpesviral-bacterial synergy in the pathogenesis of apical periodontitis: New insights and future perspectives.

    Jakovljevic, Aleksandar / Milasin, Jelena

    Journal of dental sciences

    2020  Volume 16, Issue 2, Page(s) 793–794

    Language English
    Publishing date 2020-05-16
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2213-8862
    ISSN (online) 2213-8862
    DOI 10.1016/j.jds.2020.05.001
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  7. Article ; Online: Diabetes Mellitus May Negatively Influence the Outcome of Conventional Nonsurgical Root Canal Treatment.

    Jakovljevic, Aleksandar / Duncan, Henry Fergus

    The journal of evidence-based dental practice

    2020  Volume 20, Issue 3, Page(s) 101467

    Abstract: Article title and bibliographic information: Association between diabetes and the outcome of root canal treatment in adults: an umbrella review. Nagendrababu V, Segura-Egea JJ, Fouad AF, Pulikkotil SJ, Dummer PMH. Int Endod J 2020;53(4):455-66.: ... ...

    Abstract Article title and bibliographic information: Association between diabetes and the outcome of root canal treatment in adults: an umbrella review. Nagendrababu V, Segura-Egea JJ, Fouad AF, Pulikkotil SJ, Dummer PMH. Int Endod J 2020;53(4):455-66.
    Source of funding: Authors declared that no funding was received to support the study.
    Type of study/design: Umbrella review (ie, overarching systematic review of systematic reviews).
    MeSH term(s) Adult ; Dental Pulp Cavity ; Diabetes Mellitus ; Humans ; Root Canal Therapy
    Language English
    Publishing date 2020-06-17
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 2056058-8
    ISSN 1532-3390 ; 1532-3382
    ISSN (online) 1532-3390
    ISSN 1532-3382
    DOI 10.1016/j.jebdp.2020.101467
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  8. Article ; Online: Human Cytomegalovirus May Contribute to the Development of Periodontitis, but Not to Apical Periodontitis of Endodontic Origin.

    Jakovljevic, Aleksandar / Milasin, Jelena

    The journal of evidence-based dental practice

    2020  Volume 20, Issue 4, Page(s) 101491

    Abstract: Article title and bibliographic information: Association between human cytomegalovirus and periodontitis: A systematic review and meta-analysis. Botero JE, Rodríguez-Medina C, Jaramillo-Echeverry A, Contreras A. J Periodontal Res. 2020;55(4):551-558.: ...

    Abstract Article title and bibliographic information: Association between human cytomegalovirus and periodontitis: A systematic review and meta-analysis. Botero JE, Rodríguez-Medina C, Jaramillo-Echeverry A, Contreras A. J Periodontal Res. 2020;55(4):551-558.
    Source of funding: Information not available TYPE OF STUDY/DESIGN: Systematic review with meta-analysis of data.
    MeSH term(s) Cytomegalovirus ; Humans ; Periapical Periodontitis ; Periodontitis
    Language English
    Publishing date 2020-09-15
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2056058-8
    ISSN 1532-3390 ; 1532-3382
    ISSN (online) 1532-3390
    ISSN 1532-3382
    DOI 10.1016/j.jebdp.2020.101491
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  9. Article ; Online: The Link Between Apical Periodontitis and Gastrointestinal Diseases-A Systematic Review.

    Jakovljevic, Aleksandar / Ideo, Francesca / Jacimovic, Jelena / Aminoshariae, Anita / Nagendrababu, Venkateshbabu / Azarpazhooh, Amir / Cotti, Elisabetta

    Journal of endodontics

    2023  

    Abstract: Introduction: This systematic review aimed to examine a potential link between apical periodontitis (AP) and gastrointestinal diseases (GIDs).: Methods: The protocol of the review has been registered in PROSPERO (CRD42022330771). The following ... ...

    Abstract Introduction: This systematic review aimed to examine a potential link between apical periodontitis (AP) and gastrointestinal diseases (GIDs).
    Methods: The protocol of the review has been registered in PROSPERO (CRD42022330771). The following engines were used with the aim of searching for relevant literature: PubMed, Web of Science, Scopus, Cochrane Central Register of Controlled Trials, and grey literature, from inception to May 2022. There were no language restrictions included. Study selection, data collection, and synthesis have been performed by 2 independent reviewers. For the purpose of estimating the quality of studies, the Newcastle-Ottawa Scale was used.
    Results: Four matched case control studies, as well as a single longitudinal cohort study were included in the final review. These were published between 2012 and 2017, and comprised 537 participants whose age range was 18 to 87 years. It was not possible to perform a meta-analysis due to different study designs and evaluated outcomes of included studies. Except for one study that was categorized as "Good," overall, for 4 out of 5 studies the quality was assessed as "Fair".
    Conclusions: This review highlighted sparse knowledge present in the literature concerned with the association between AP and GIDs. Available evidence reveals a potential link between impaired endodontic status, assessed by the number of root-filled teeth with periapical radiolucency, and GIDs. More research is needed to ascertain this association.
    Language English
    Publishing date 2023-08-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 752412-2
    ISSN 1878-3554 ; 0099-2399
    ISSN (online) 1878-3554
    ISSN 0099-2399
    DOI 10.1016/j.joen.2023.07.024
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  10. Article ; Online: Gene polymorphisms in odontogenic keratocysts and ameloblastomas: A systematic review.

    Andric, Miroslav / Jacimovic, Jelena / Jakovljevic, Aleksandar / Nikolic, Nadja / Milasin, Jelena

    Oral diseases

    2021  Volume 28, Issue 6, Page(s) 1421–1430

    Abstract: Objectives: The aim of this systematic review was to critically analyze available data on gene polymorphisms in odontogenic keratocysts (OKC) and ameloblastomas, including their possible relationship with clinical and histological features of these ... ...

    Abstract Objectives: The aim of this systematic review was to critically analyze available data on gene polymorphisms in odontogenic keratocysts (OKC) and ameloblastomas, including their possible relationship with clinical and histological features of these lesions.
    Materials and methods: A comprehensive search of Web of Science Scopus, PubMed, Cochrane Central Register of Controlled Trials and EMBASE was conducted using relevant key terms and supplemented by a gray literature search. Quality assessment of included studies was performed using criteria from the Strengthening the Reporting of Genetic Association (STREGA) statement.
    Results: Ten studies were included in the final review. Survivin -31G/C, interleukin IL-1α -889 C/T, p53 codon 72 G/C, tumor necrosis factor TNF-α (-308G>A) and its receptor TNF-R1 (36A>G), glioma-associated oncogene homolog 1 rs2228224 and matrix metalloproteinase 2 rs243865 gene polymorphisms were reported to be associated with OKC. For ameloblastomas, p53 codon 72 G/C, X-ray repair cross-complementing protein 1-codons 194 and 399 and matrix metalloproteinase 9 rs3918242 gene polymorphisms were identified as risk factors. It was not possible to establish a relationship between specific polymorphisms and clinical and histological features of investigated lesions.
    Conclusions: Several gene polymorphisms might be considered as a risk factor for the development of these lesions. Future studies should investigate whether these polymorphisms might be used to identify patients with increased risk of recurrence or aggressive disease.
    MeSH term(s) Ameloblastoma/pathology ; Humans ; Matrix Metalloproteinase 2/metabolism ; Odontogenic Cysts/genetics ; Odontogenic Cysts/pathology ; Odontogenic Tumors ; Polymorphism, Genetic ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism ; Tumor Suppressor Protein p53
    Chemical Substances Tumor Necrosis Factor-alpha ; Tumor Suppressor Protein p53 ; Matrix Metalloproteinase 2 (EC 3.4.24.24)
    Language English
    Publishing date 2021-04-08
    Publishing country Denmark
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.13865
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