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  1. Book: Primer on prostate cancer

    James, Nicholas

    2014  

    Author's details Nicholas James
    Keywords Prostate/Cancer
    Subject code 616.99463
    Language English
    Size VIII, 50 S. : Ill., graph. Darst., 21 cm
    Publisher Springer Healthcare
    Publishing place London
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references
    HBZ-ID HT018439729
    ISBN 978-1-907673-81-8 ; 1-907673-81-4
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: The Evolving Spectrum of Inflammatory Demyelination of the Central Nervous System in Children.

    Brenton, James Nicholas

    Seminars in pediatric neurology

    2023  Volume 46, Page(s) 101057

    MeSH term(s) Humans ; Child ; Central Nervous System ; Demyelinating Diseases
    Language English
    Publishing date 2023-05-09
    Publishing country United States
    Document type Editorial
    ZDB-ID 1290000-x
    ISSN 1558-0776 ; 1071-9091
    ISSN (online) 1558-0776
    ISSN 1071-9091
    DOI 10.1016/j.spen.2023.101057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Environmental Influences on Risk and Disease Course in Pediatric Multiple Sclerosis.

    Dinov, Darina / Brenton, James Nicholas

    Seminars in pediatric neurology

    2023  Volume 46, Page(s) 101049

    Abstract: Pediatric multiple sclerosis (MS) accounts for 3%-10% of all patients diagnosed with MS. Complex interplay between environmental factors impacts the risk for MS and may also affect disease course. Many of these environmental factors are shared with adult- ...

    Abstract Pediatric multiple sclerosis (MS) accounts for 3%-10% of all patients diagnosed with MS. Complex interplay between environmental factors impacts the risk for MS and may also affect disease course. Many of these environmental factors are shared with adult-onset MS. However, children with MS are in closer temporal proximity to the biological onset of MS and have less confounding environmental exposures than their adult counterparts. Environmental factors that contribute to MS risk include: geographical latitude, viral exposures, obesity, vitamin deficiencies, smoking, air pollution, perinatal factors, gut microbiome, and diet. More recently, research efforts have shifted to studying the impact of these risk determinants on the clinical course of MS. In this article we will examine relevant environmental risk determinants of pediatric MS and review the current knowledge on how these factors may contribute to pediatric MS disease evolution.
    MeSH term(s) Adult ; Pregnancy ; Female ; Child ; Humans ; Multiple Sclerosis/epidemiology ; Multiple Sclerosis/etiology ; Risk Factors ; Environmental Exposure/adverse effects ; Disease Progression
    Language English
    Publishing date 2023-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1290000-x
    ISSN 1558-0776 ; 1071-9091
    ISSN (online) 1558-0776
    ISSN 1071-9091
    DOI 10.1016/j.spen.2023.101049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: How to Compose Platform Trials.

    Clarke, Noel W / James, Nicholas D

    European urology focus

    2023  Volume 9, Issue 5, Page(s) 715–718

    Abstract: Platform trials are adaptive randomised controlled trials that address multiple questions using a single protocol, which reduces the time taken to reach a meaningful trial endpoint. This mini review provides a description of how to conceive, design, and ... ...

    Abstract Platform trials are adaptive randomised controlled trials that address multiple questions using a single protocol, which reduces the time taken to reach a meaningful trial endpoint. This mini review provides a description of how to conceive, design, and carry out a platform trial in urology, using experience gained in the STAMPEDE trial. PATIENT SUMMARY: Clinical trials to test how well a new drug or treatment works can take a long time before meaningful results can be assessed. Trials with a platform design can test multiple treatments using just one protocol and control, which reduces the time taken to reach a trial endpoint.
    MeSH term(s) Humans ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2023-11-03
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2405-4569
    ISSN (online) 2405-4569
    DOI 10.1016/j.euf.2023.10.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Trauma Bay Evaluation and Resuscitative Decision-Making.

    Leeper, William Robert / James, Nicholas

    The Surgical clinics of North America

    2023  Volume 104, Issue 2, Page(s) 293–309

    Abstract: The reader of this article will now have the ability to reflect on all aspects of high-quality trauma bay care, from resuscitation to diagnosis and leadership to debriefing. Although there is no replacement for experience, both clinically and in a ... ...

    Abstract The reader of this article will now have the ability to reflect on all aspects of high-quality trauma bay care, from resuscitation to diagnosis and leadership to debriefing. Although there is no replacement for experience, both clinically and in a simulation environment, trauma clinicians are encouraged to make use of this article both as a primer at the beginning of a trauma rotation and a reference text to revisit after difficult cases in the trauma bay. Also, periods of reflection seem appropriate in the busy but, of course, rewarding career in trauma care.
    MeSH term(s) Humans ; Resuscitation ; Resuscitation Orders ; Leadership ; Clinical Competence ; Quality of Health Care ; Patient Care Team
    Language English
    Publishing date 2023-10-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 215713-5
    ISSN 1558-3171 ; 0039-6109
    ISSN (online) 1558-3171
    ISSN 0039-6109
    DOI 10.1016/j.suc.2024.01.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Oligometastatic Prostate Cancer Should Be Studied and Treated Differently to High-volume Disease. Con: The Underlying Biology is the Same, So They Should Not Be Treated Differently.

    James, Nicholas D

    European urology focus

    2019  Volume 5, Issue 2, Page(s) 119–122

    Abstract: The biology of oligo- and polymetastatic disease is likely to be similar. However, the prognosis is different and this may drive different therapy choices. Men should not be deprived of life-prolonging therapies unless the benefits of these therapies are ...

    Abstract The biology of oligo- and polymetastatic disease is likely to be similar. However, the prognosis is different and this may drive different therapy choices. Men should not be deprived of life-prolonging therapies unless the benefits of these therapies are outweighed by the risks from competing causes of mortality.
    MeSH term(s) Androstenes/therapeutic use ; Cost of Illness ; Docetaxel/therapeutic use ; Humans ; Male ; Molecular Biology/methods ; Neoplasm Metastasis/diagnostic imaging ; Neoplasm Metastasis/genetics ; Neoplasm Metastasis/pathology ; Neoplasm Metastasis/therapy ; Phenotype ; Positron-Emission Tomography/methods ; Prognosis ; Prostate-Specific Antigen/metabolism ; Prostatic Neoplasms/classification ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms/secondary ; Prostatic Neoplasms/therapy ; Radiotherapy/methods ; Tubulin Modulators/therapeutic use ; Whole Body Imaging/methods
    Chemical Substances Androstenes ; Tubulin Modulators ; Docetaxel (15H5577CQD) ; Prostate-Specific Antigen (EC 3.4.21.77) ; abiraterone (G819A456D0)
    Language English
    Publishing date 2019-02-23
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2405-4569
    ISSN (online) 2405-4569
    DOI 10.1016/j.euf.2019.01.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Prognostic and predictive models in hormone-sensitive prostate cancer.

    James, Nicholas D

    BJU international

    2018  Volume 122, Issue 3, Page(s) 352–353

    MeSH term(s) Humans ; Male ; Prognosis ; Prostate-Specific Antigen ; Prostatic Neoplasms
    Chemical Substances Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2018-09-05
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1462191-5
    ISSN 1464-410X ; 1464-4096 ; 1358-8672
    ISSN (online) 1464-410X
    ISSN 1464-4096 ; 1358-8672
    DOI 10.1111/bju.14395
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Harmonics, evolutionary generators, DANCE, and HEAR-functional dimensions.

    Furze, James Nicholas / Mayad, El Hassan

    Environmental science and pollution research international

    2021  Volume 28, Issue 45, Page(s) 64181–64190

    Abstract: Evolution of the major kingdoms of life has spanned over the last 4 billion years on Earth. Studies of the process comprise different fields of study with alternative perspectives. This paper focuses on mathematic unification of the subject area; ... ...

    Abstract Evolution of the major kingdoms of life has spanned over the last 4 billion years on Earth. Studies of the process comprise different fields of study with alternative perspectives. This paper focuses on mathematic unification of the subject area; enriching an engineering based structure to advance our understanding of pathways which lead to distinct constructs in life, furthering geographic bordering processes with biological context. Application of logistic regression requires partitioning of variance within cellular and molecular systems; use of higher mathematic technique (multi-objective genetic algorithm) generates variance within the different scales of evolution, the result of which is analogous with the Fisher equation model of gene distribution within populations. Laboratory and field studies were integrated to illustrate emergence in evolutionary processes in the terrestrial/soil environment. Nematological field and laboratory trials validate the existence of triangular relationships within biological communities; further harmonic constants between interacting species may be found with emergent consequence. We distinguish different strategical groupings in the soil community, with the core groupings recognized with Meloidogyne spp. illustrating positive (emergent) growth; Radopholus similis (neutral growth), and Helicotylenchus pseudorobustus (negative growth). The patterns of emergent systems are shown in the extremes of Morocco's dynamic soil environment. Fuzzy classification methods: Mamdani, Takugi-Sugeno-Kang; additional novel DANCE (Differential Algorithmic Network Centered Emergence) and functional expressions HEAR (Harmonic Evolutionary Algorithmic Resilience), are recommended to give a basis for development of constructs covering different categories of life.
    Language English
    Publishing date 2021-04-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-13159-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Vertical phytoremediation of wastewater using Vetiveria zizanioides L.

    Parnian, Amir / Furze, James Nicholas

    Environmental science and pollution research international

    2021  Volume 28, Issue 45, Page(s) 64150–64155

    Abstract: In many areas, wastewater feeds water bodies, which leads to it being non-usable for agricultural and other uses. Phytoremediation is a scientific approach which cleans contaminated waters, demanding large areas for application. Vertical agriculture is a ...

    Abstract In many areas, wastewater feeds water bodies, which leads to it being non-usable for agricultural and other uses. Phytoremediation is a scientific approach which cleans contaminated waters, demanding large areas for application. Vertical agriculture is a new method to compact plant cultures. This study investigates vertical wastewater phytoremediation (VWP). Twenty vetiver grasses were planted in a hydroponic vertical agriculture system. Wastewater flowed into the system in four different flow rates, 60, 80, 100, and 160 l day
    MeSH term(s) Biodegradation, Environmental ; Chrysopogon ; Ecosystem ; Humans ; Hydroponics ; Waste Water
    Chemical Substances Waste Water
    Language English
    Publishing date 2021-01-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-020-11906-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Correction to: Harmonics, evolutionary generators, DANCE, and HEAR-functional dimensions.

    Furze, James Nicholas / Mayad, El Hassan

    Environmental science and pollution research international

    2021  Volume 28, Issue 45, Page(s) 64191–64192

    Language English
    Publishing date 2021-09-25
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-15053-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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