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Article ; Online: Eid-al-Fitr festivity and Ramadan fasting attitude among individuals with diabetes from Saudi Arabia and Pakistan: a cross-sectional study.

Gazzaz, Zohair J / Baig, Mukhtiar / Kanpurwala, Muhammad Adnan / Jamil, Tahir / Mojaddidi, Moaz A / Murad, Manal A

2022 Volume 12, Issue 9, Page(s) e054902

Abstract: Objectives: The present study aimed to assess the attitude of Saudi and Pakistani individuals with diabetes regarding Eid-al-Fitr festivities, exploring diabetes care during the month of Ramadan and these individuals' dietary patterns on Eid day.: ... ...

Abstract	Objectives: The present study aimed to assess the attitude of Saudi and Pakistani individuals with diabetes regarding Eid-al-Fitr festivities, exploring diabetes care during the month of Ramadan and these individuals' dietary patterns on Eid day. Design: Cross-sectional study. Setting: Jeddah (Saudi Arabia) and Karachi (Pakistan). Participants: Of the total 405 subjects, 204 individuals with diabetes from Saudi Arabia (SA) and 201 from Pakistan (Pak) were enrolled. Data collection and analysis: This survey-based study was carried out in SA and Pak after Eid-al-Fitr 2020. An online questionnaire was circulated via various social media platforms. The data analyses were performed using SPSS V.26. Results: There were 80 subjects with type 1 diabetes mellitus (DM) and 325 subjects with type 2 DM. Among our study subjects, 73 were on insulin, 260 were on oral antidiabetics (OADs) and 72 were taking both OADs and insulin. Two-thirds of the participants, 276 (68%) visited their physicians before Ramadan. Many participants (175, 43.2%) broke their fast a day or more because of diabetes. Many participants consumed sugary food on Eid day. The use of chocolates, sugary foods and fresh juices on Eid-al-Fitr was higher in Saudi subjects than in Pakistani ones (p<0.001). Saudi subjects with diabetes adhered more strictly to medications during Ramadan than Pakistani subjects (p=0.01). Saudi participants were more compliant with monitoring DM during Eid-al-Fitr compared with Pakistani subjects. Many participants in both groups felt stressed or depressed and stated that their Eid celebrations were restrictive because of their DM conditions. Conclusions: Most Saudi and Pakistani participants enjoyed Eid celebrations by abstaining from dietary restrictions. The sugar consumption attitude during Eid day was not up to the mark. Many subjects broke their fasts for a day or more because of diabetes. Saudis were more vigilant in monitoring DM than Pakistanis during Eid-al-Fitr. Individuals with diabetes should consult their physicians before Ramadan for checkups and counselling.
MeSH term(s)	Humans ; Saudi Arabia ; Pakistan ; Cross-Sectional Studies ; Fasting ; Hypoglycemic Agents/therapeutic use ; Insulin/therapeutic use ; Diabetes Mellitus/drug therapy
Chemical Substances	Hypoglycemic Agents ; Insulin
Language	English
Publishing date	2022-09-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2021-054902
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Resistance of high-temperature cuprate superconductors

Jamil Tahir-Kheli

New Journal of Physics, Vol 15, Iss 7, p

2013 Volume 073020

Abstract: Cuprate superconductors have many different atoms per unit cell. A large fraction of cells (5–25%) must be modified (‘doped’) before the material superconducts. Thus it is not surprising that there is little consensus on the superconducting mechanism, ... ...

Abstract	Cuprate superconductors have many different atoms per unit cell. A large fraction of cells (5–25%) must be modified (‘doped’) before the material superconducts. Thus it is not surprising that there is little consensus on the superconducting mechanism, despite almost 200 000 papers (Mann 2011 Nature 475 280). Most astonishing is that for the simplest electrical property, the resistance, ‘despite sustained theoretical efforts over the past two decades, its origin and its relation to the superconducting mechanism remain a profound, unsolved mystery’ (Hussey et al 2011 Phil. Trans. R. Soc. A 369 1626). Currently, model parameters used to fit normal state properties are experiment specific and vary arbitrarily from one doping to the other. Here, we provide a quantitative explanation for the temperature and doping dependence of the resistivity in one self-consistent model by showing that cuprates are intrinsically inhomogeneous with a percolating metallic region and insulating regions. Using simple counting of dopant-induced plaquettes, we show that the superconducting pairing and resistivity are due to phonons.
Keywords	Science ; Q ; Physics ; QC1-999
Language	English
Publishing date	2013-01-01T00:00:00Z
Publisher	IOP Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Formulation, evaluation and in vitro characterization of gastroretentive floating tablet of diclofenac sodium.

Shehzad, Muhammad Qaiser / Nazir, Taha / Nazir, Saeed-Ur-Rashid / Taha, Nida / Jamil, Tahir / Akram, Muhammad Abdullah

Pakistan journal of pharmaceutical sciences

2020 Volume 32, Issue 6, Page(s) 2573–2578

Abstract: Currently a variety of tools and techniques are used to deliver complex medicines. Whereas, certain advanced methods assure the safety and usefulness by regulating the pharmacokinetic and pharmacodynamic. Thus, we aimed this study to develop a novel ... ...

Abstract	Currently a variety of tools and techniques are used to deliver complex medicines. Whereas, certain advanced methods assure the safety and usefulness by regulating the pharmacokinetic and pharmacodynamic. Thus, we aimed this study to develop a novel gastro retentive floating tablets. The formulation was designed to provide the desired controlled and complete release of drug for prolonged period of time. The formulations were evaluated for physical characterization. The obtained results of hardness (4.6-5.1), friability (0.20-0.43%), weight variation (350 ±2 - 350±5) and in vitro buoyancy were found within official limits of United Stated Pharmacopoeia (USP). Whereas, the F-7 showed most optimized intra gastric floating characteristics and exhibited 93.87% release of diclofenac sodium in 9 hours. The Floating Lag Time of 8 minutes and Total Floating Time >12 hours were recorded. In-vitro drug release kinetics evaluated using the linear regression method was found to follow the Zero Order and Peppas model for the release of both the drugs. DSC thermograph and FTIR spectra depicted that there was no chemical incompatibility between drugs and polymers. In conclusion the desgined tablet can be use in clinical practice as model drug. Because, the pre-compression and post-compression parameters were satisfactory and within desired limits.
MeSH term(s)	Delayed-Action Preparations/administration & dosage ; Delayed-Action Preparations/pharmacokinetics ; Diclofenac/administration & dosage ; Diclofenac/pharmacokinetics ; Drug Compounding/methods ; Drug Liberation ; Humans ; Spectroscopy, Fourier Transform Infrared ; Tablets
Chemical Substances	Delayed-Action Preparations ; Tablets ; Diclofenac (144O8QL0L1)
Language	English
Publishing date	2020-01-22
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	885131-1
ISSN	1011-601X
ISSN	1011-601X
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Article ; Online: Robotic repair of symptomatic Spigelian hernias: a series of three cases and surgical technique review.

Jamshidian, Mitra / Stanek, Stephen / Sferra, Joseph / Jamil, Tahir

Journal of robotic surgery

2017 Volume 12, Issue 3, Page(s) 557–560

Abstract: Spigelian hernias are a rare defect in the Spigelian aponeurosis, comprising of 0.1-2% of all hernias. These rare hernias can contain intra-abdominal tissue, and rarely bladder. Spigelian hernias pose a high risk for incarceration or strangulation of its ...

Abstract	Spigelian hernias are a rare defect in the Spigelian aponeurosis, comprising of 0.1-2% of all hernias. These rare hernias can contain intra-abdominal tissue, and rarely bladder. Spigelian hernias pose a high risk for incarceration or strangulation of its herniated content if not repaired promptly. There are a number of routinely employed operative techniques to repair Spigelian hernias, including open or laparoscopic, suture or mesh repair, transabdominal pre-peritoneal approach or totally extraperitoneal approach. Robotic Spigelian repairs have been rarely reported in the literature. We report three cases of incarcerated Spigelian hernias that were successfully repaired robotically with mesh.
MeSH term(s)	Abdomen/diagnostic imaging ; Aged ; Hernia, Abdominal/surgery ; Humans ; Male ; Robotic Surgical Procedures/instrumentation ; Robotic Surgical Procedures/methods ; Surgical Mesh ; Tomography, X-Ray Computed
Language	English
Publishing date	2017-08-28
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2268283-1
ISSN	1863-2491 ; 1863-2483
ISSN (online)	1863-2491
ISSN	1863-2483
DOI	10.1007/s11701-017-0742-9
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Article ; Online: Decoration of open pore network in Polyvinylidene fluoride/MWCNTs with chitosan for the removal of reactive orange 16 dye.

Wasim, Maria / Sagar, Sadia / Sabir, Aneela / Shafiq, Muhammad / Jamil, Tahir

Carbohydrate polymers

2017 Volume 174, Page(s) 474–483

Abstract: Inspired by the hydrophilic, biocompatible, adsorbent properties of chitosan. A simple, adaptable, green synthesis method was developed to prepare a thin film composite membranes using chitosan as a pore decorating material for the removal of anionic dye- ...

Abstract	Inspired by the hydrophilic, biocompatible, adsorbent properties of chitosan. A simple, adaptable, green synthesis method was developed to prepare a thin film composite membranes using chitosan as a pore decorating material for the removal of anionic dye-Reactive orange 16 (RO-16). The hydrophilic chitosan was used to fill up the porous hydrophobic PVDF substrate, modified by MWCNTs. The dye rejection was carried out through the formation of a strong electrostatic interaction between the cationic group of chitosan surface and the anionic group of RO-16 dye. The dye molecules accumulate on the chitosan surface, thus promoting the higher retention rate. The TFC membranes were evaluated using dead filtration plant. It is found that the modified membranes showed RO-16 rejection up to 91% with optimum permeation flux of 170kgm
Language	English
Publishing date	2017-10-15
Publishing country	England
Document type	Journal Article
ZDB-ID	1501516-6
ISSN	1879-1344 ; 0144-8617
ISSN (online)	1879-1344
ISSN	0144-8617
DOI	10.1016/j.carbpol.2017.06.086
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Article: Formulation of novel chitosan guargum based hydrogels for sustained drug release of paracetamol

Sami, Amtul Jamil / Khalid, Madeeha / Jamil, Tahir / Aftab, Saira / Mangat, Sermad Ahmad / Shakoori, A.R / Iqbal, Sara

International journal of biological macromolecules. 2018 Mar., v. 108

2018

Abstract: The report presents the formulation of hydrogel based on biopolymers chitosan and guar gum after cross-linking for sustained release of a commonly used orally prescribed analgesic Paracetamol. The oral ingestion of Paracetamol is associated with ... ...

Abstract	The report presents the formulation of hydrogel based on biopolymers chitosan and guar gum after cross-linking for sustained release of a commonly used orally prescribed analgesic Paracetamol. The oral ingestion of Paracetamol is associated with complications of the gastric tract and liver metabolism that can be effectually avoided by using transdermal drug delivery systems. The formulated transdermal patch was characterized for physicochemical properties including swelling, bonding pattern (using FTIR Fourier Transform Infra-Red and Scanning Electron Microscopy SEM) and antimicrobial activity. Biocompatibility and cytotoxicity was examined in vitro using cell culture in HeLa cell lines. After characterizing the novel formulated hydrogel were employed for the preparation of drug encapsulated in alginate beads as a transdermal patch. After formulation of the transdermal patch, the drug release was studied using an avian skin model. The results followed zero order kinetics and Non-Fickian law for diffusion. Paracetamol due to its small molecular mass (151.163g/mol) released in a sustained manner. The released drug successfully retained its biological effects including anti-inflammatory and anti-protease activity, indicating no interaction between the drug and the formulated hydrogel. It was shown that the formulated hydrogels could be safely used as a dermal patch for the sustained drug release of Paracetamol.
Keywords	Fourier transform infrared spectroscopy ; acetaminophen ; alginates ; antimicrobial properties ; biocompatibility ; biopolymers ; birds ; cell culture ; chitosan ; crosslinking ; cytotoxicity ; drug delivery systems ; guar gum ; human cell lines ; hydrogels ; ingestion ; liver ; metabolism ; models ; molecular weight ; scanning electron microscopy
Language	English
Dates of publication	2018-03
Size	p. 324-332.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2017.12.008
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Performance behavior of modified cellulosic fabrics using polyurethane acrylate copolymer.

Zuber, Mohammad / Shah, Sayyed Asim Ali / Jamil, Tahir / Asghar, Muhammad Irfan

International journal of biological macromolecules

2014 Volume 67, Page(s) 254–259

Abstract: The surface of the cellulosic fabrics was modified using self-prepared emulsions of polyurethane acrylate copolymers (PUACs). PUACs were prepared by varying the molecular weight of polycaprolactone diol (PCL). The PCL was reacted with isophorone ... ...

Abstract	The surface of the cellulosic fabrics was modified using self-prepared emulsions of polyurethane acrylate copolymers (PUACs). PUACs were prepared by varying the molecular weight of polycaprolactone diol (PCL). The PCL was reacted with isophorone diisocyanate (IPDI) and chain was extended with 2-hydroxy ethyl acrylate (HEA) to form vinyl terminated polyurethane (VTPU) preploymer. The VTPU was further co-polymerized through free radical polymerization with butyl acrylate in different proportions. The FT-IR spectra of monomers, prepolymers and copolymers assured the formation of proposed PUACs structure. The various concentrations of prepared PUACs were applied onto the different fabric samples using dip-padding techniques. The results revealed that the application of polyurethane butyl acrylate copolymer showed a pronounced effect on the tear strength and pilling resistance of the treated fabrics.
MeSH term(s)	Acrylates/chemistry ; Cellulose/chemistry ; Polymerization ; Polymers/chemistry ; Polyurethanes/chemistry ; Spectroscopy, Fourier Transform Infrared ; Textiles
Chemical Substances	Acrylates ; Polymers ; Polyurethanes ; ethyl acrylate (71E6178C9T) ; Cellulose (9004-34-6)
Language	English
Publishing date	2014-06
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2014.03.021
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Article ; Online: Co-concentration effect of silane with natural extract on biodegradable polymeric films for food packaging.

Bashir, Anbreen / Jabeen, Sehrish / Gull, Nafisa / Islam, Atif / Sultan, Misbah / Ghaffar, Abdul / Khan, Shahzad Maqsood / Iqbal, Sadia Sagar / Jamil, Tahir

International journal of biological macromolecules

2018 Volume 106, Page(s) 351–359

Abstract: Novel biodegradable films were prepared by blending guar gum, chitosan and poly (vinyl alcohol) having mint (ME) and grapefruit peel (GE) extracts and crosslinked with nontoxic tetraethoxysilane (TEOS). The co-concentration effect of TEOS with natural ... ...

Abstract	Novel biodegradable films were prepared by blending guar gum, chitosan and poly (vinyl alcohol) having mint (ME) and grapefruit peel (GE) extracts and crosslinked with nontoxic tetraethoxysilane (TEOS). The co-concentration effect of TEOS with natural extracts on the films was studied. FTIR analysis confirmed the presence of incorporated components and the developed interactions among the polymer chains. The surface morphology of the films by SEM showed the hydrophilic character due to porous network structure. The films having both ME and GE with maximum amount of crosslinker (100μL), showed maximum swelling (58g/g) and stability while the optical properties showed increased protection against UV light. This film sample showed compact network structure which enhanced the ultimate tensile strength (40.03MPa) and elongation at break (104.8%). ME/GE conferred the antioxidant properties determined by radical scavenging activity and total phenolic contents (TPC) as ME films have greater TPC compared to GE films. The soil burial test exhibited the degradation of films rapidly (6days) confirming their strong microbial activity in soil. The lower water vapour transmission rate and water vapour permeability showed better shelf life; hence, these biodegradable films are environmental friendly and have potential for food and other packaging.
MeSH term(s)	Biodegradation, Environmental ; Chitosan/chemistry ; Citrus paradisi/chemistry ; Cross-Linking Reagents/chemistry ; Food Packaging/methods ; Galactans/chemistry ; Humans ; Mannans/chemistry ; Membranes, Artificial ; Mentha/chemistry ; Plant Extracts/chemistry ; Plant Gums/chemistry ; Polyvinyl Alcohol/chemistry ; Porosity ; Silanes/chemistry ; Steam/analysis ; Tensile Strength ; Ultraviolet Rays
Chemical Substances	Cross-Linking Reagents ; Galactans ; Mannans ; Membranes, Artificial ; Plant Extracts ; Plant Gums ; Silanes ; Steam ; tetraethoxysilane (42064KRE49) ; Polyvinyl Alcohol (9002-89-5) ; Chitosan (9012-76-4) ; guar gum (E89I1637KE)
Language	English
Publishing date	2018-01
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2017.08.025
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Article ; Online: Formulation of novel chitosan guargum based hydrogels for sustained drug release of paracetamol.

Sami, Amtul Jamil / Khalid, Madeeha / Jamil, Tahir / Aftab, Saira / Mangat, Sermad Ahmad / Shakoori, A R / Iqbal, Sara

International journal of biological macromolecules

2018 Volume 108, Page(s) 324–332

Abstract	The report presents the formulation of hydrogel based on biopolymers chitosan and guar gum after cross-linking for sustained release of a commonly used orally prescribed analgesic Paracetamol. The oral ingestion of Paracetamol is associated with complications of the gastric tract and liver metabolism that can be effectually avoided by using transdermal drug delivery systems. The formulated transdermal patch was characterized for physicochemical properties including swelling, bonding pattern (using FTIR Fourier Transform Infra-Red and Scanning Electron Microscopy SEM) and antimicrobial activity. Biocompatibility and cytotoxicity was examined in vitro using cell culture in HeLa cell lines. After characterizing the novel formulated hydrogel were employed for the preparation of drug encapsulated in alginate beads as a transdermal patch. After formulation of the transdermal patch, the drug release was studied using an avian skin model. The results followed zero order kinetics and Non-Fickian law for diffusion. Paracetamol due to its small molecular mass (151.163g/mol) released in a sustained manner. The released drug successfully retained its biological effects including anti-inflammatory and anti-protease activity, indicating no interaction between the drug and the formulated hydrogel. It was shown that the formulated hydrogels could be safely used as a dermal patch for the sustained drug release of Paracetamol.
MeSH term(s)	Acetaminophen/administration & dosage ; Acetaminophen/chemistry ; Acetaminophen/pharmacokinetics ; Animals ; Anti-Infective Agents/chemistry ; Anti-Infective Agents/pharmacology ; Cell Line ; Cell Survival/drug effects ; Chickens ; Chitosan/chemistry ; Delayed-Action Preparations ; Diffusion ; Drug Carriers/chemistry ; Drug Compounding ; Drug Liberation ; Galactans/chemistry ; Humans ; Hydrogels/chemistry ; Mannans/chemistry ; Plant Gums/chemistry ; Spectroscopy, Fourier Transform Infrared
Chemical Substances	Anti-Infective Agents ; Delayed-Action Preparations ; Drug Carriers ; Galactans ; Hydrogels ; Mannans ; Plant Gums ; Acetaminophen (362O9ITL9D) ; Chitosan (9012-76-4) ; guar gum (E89I1637KE)
Language	English
Publishing date	2018-03
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2017.12.008
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Article ; Online: γ-Irradiated chitosan based injectable hydrogels for controlled release of drug (Montelukast sodium).

Hafeez, Sadaf / Islam, Atif / Gull, Nafisa / Ali, Abbas / Khan, Shahzad Maqsood / Zia, Saba / Anwar, Kalsoom / Khan, Saba Urooge / Jamil, Tahir

International journal of biological macromolecules

2018 Volume 114, Page(s) 890–897

Abstract: Novel pH-sensitive γ-irradiated low molecular weight (MW) chitosan (CS) (pre-irradiated) and poly (vinyl alcohol) (PVA) blended injectable hydrogels, crosslinked with varying concentrations of glycerol, were fabricated for drug delivery application. The ... ...

Abstract	Novel pH-sensitive γ-irradiated low molecular weight (MW) chitosan (CS) (pre-irradiated) and poly (vinyl alcohol) (PVA) blended injectable hydrogels, crosslinked with varying concentrations of glycerol, were fabricated for drug delivery application. The effect of low MW irradiated CS on controlled drug release was evaluated to address the problem of higher viscosity and lower solubility of high MW CS. The FTIR spectra of hydrogels depicted the presence of all the incorporated functional groups and the developed interactions (physical and chemical). The surface morphology of hydrogels assessed by scanning electron microscope exhibited porous microstructure. All hydrogels were subjected to the swelling analysis in different media (water, buffer and electrolytes). The pH sensitive hydrogel samples exhibited less swelling at acidic and neutral pH while higher swelling at basic pH. CPG-0.5 showed the highest swelling at all pH media as compared to other hydrogel samples. CPG-1.0 was selected for the release analysis of drug because of its highest swelling (114.47%) in distilled water having neutral pH. It was loaded with model drug (Montelukast Sodium) during the preparation phase and studied for drug release capability. The in-vitro controlled release evaluation of hydrogel (CPG-1.0) was performed in SGF and SIF using UV-visible spectroscopy. The results confirmed their applications in injectable drug release systems as all the loaded drug was released in 30 min in SGF (pH -1.2) while the release of drug in SIF (pH -6.8) was in controlled manner (99.62% in 3 h). The improved antibacterial activity of these hydrogel films was owing to the fact that the γ-irradiated low MW CS has ruptured the bacterial cell and its metabolism more efficiently by inflowing in the cell.
MeSH term(s)	Acetates/administration & dosage ; Chitosan/administration & dosage ; Chitosan/chemistry ; Chitosan/radiation effects ; Cross-Linking Reagents/pharmacology ; Delayed-Action Preparations ; Drug Delivery Systems ; Drug Evaluation, Preclinical ; Drug Liberation ; Escherichia coli/drug effects ; Gamma Rays ; Glycerol/pharmacology ; Hydrogels/administration & dosage ; Hydrogels/chemistry ; Hydrogels/radiation effects ; Hydrogen Bonding ; Hydrogen-Ion Concentration ; Hydrophobic and Hydrophilic Interactions ; Microscopy, Electron, Scanning ; Molecular Weight ; Polyvinyl Alcohol/administration & dosage ; Porosity ; Quinolines/administration & dosage ; Spectrophotometry, Ultraviolet ; Spectroscopy, Fourier Transform Infrared
Chemical Substances	Acetates ; Cross-Linking Reagents ; Delayed-Action Preparations ; Hydrogels ; Quinolines ; Polyvinyl Alcohol (9002-89-5) ; Chitosan (9012-76-4) ; montelukast (MHM278SD3E) ; Glycerol (PDC6A3C0OX)
Language	English
Publishing date	2018-02-17
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2018.02.107
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