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  1. Article: Collodion phenotype remains a challenge for neonatologists: A rare case of self-healing collodion baby.

    Zdraveska, Nikolina / Kostovski, Aco / Sofijanova, Aspazija / Jancevska, Snezana / Damevska, Katerina

    Clinical case reports

    2022  Volume 10, Issue 7, Page(s) e6158

    Abstract: We report a unique case of self-healing collodion baby (CB) that was successfully managed despite the risk of potentially serious complications. Self-healing CB is a rare and distinct outcome of collodion phenotype occurring in approximately 10% of the ... ...

    Abstract We report a unique case of self-healing collodion baby (CB) that was successfully managed despite the risk of potentially serious complications. Self-healing CB is a rare and distinct outcome of collodion phenotype occurring in approximately 10% of the cases. The outcome depends on the initial assessment and adequate multidisciplinary approach.
    Language English
    Publishing date 2022-07-27
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.6158
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Neonatal lupus erythematosus-a rare syndrome of transient autoimmunity.

    Zdraveska, Nikolina / Kostovski, Aco / Sofijanova, Aspazija / Jancevska, Snezana / Jovanovska, Jana / Kacarska, Milena / Damevska, Katerina

    Clinical case reports

    2022  Volume 10, Issue 6, Page(s) e6004

    Abstract: Neonatal lupus erythematosus (NLE) is a rare autoimmune disease due to a passive transfer of maternal autoantibodies to the fetus. The clinical spectrum is variable and includes skin lesions, cardiac, hematological, or hepatobiliary disorders. We report ... ...

    Abstract Neonatal lupus erythematosus (NLE) is a rare autoimmune disease due to a passive transfer of maternal autoantibodies to the fetus. The clinical spectrum is variable and includes skin lesions, cardiac, hematological, or hepatobiliary disorders. We report an NLE case presenting with skin eruption that was initially considered as tinea.
    Language English
    Publishing date 2022-06-24
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.6004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Neonatal Hypoglycemia: Risk Factors and Outcomes.

    Stomnaroska, Orhideja / Petkovska, Elizabeta / Jancevska, Snezana / Danilovski, Dragan

    Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)

    2017  Volume 38, Issue 1, Page(s) 97–101

    Abstract: Background and aims: Severe neonatal hypoglycemia (HG) leads to neurologic damage, mental retardation, epilepsy, personality disorders, impaired cardiac performance and muscle weakness. We aimed to assess the clinical characteristics of children with ... ...

    Abstract Background and aims: Severe neonatal hypoglycemia (HG) leads to neurologic damage, mental retardation, epilepsy, personality disorders, impaired cardiac performance and muscle weakness. We aimed to assess the clinical characteristics of children with hypoglycemia in a random population of newborns.
    Patients, methods and results: We investigated 84 patients (M:F=35:48) born at the University Clinic for Gynecology and Obstetrics in Skopje (hospitalized in the NICU) who were found to have hypoglycemia. In total 89.25% of the babies were premature. The mean birth weight was 1795.95 +/596.08 grams, the mean birth length was 41.92+/- 4.62 cm, while the mean gestational age was 33.05±3.19 weeks. 32 children (38.08%) were very low birth weight (<1500g), 38 (45.22%) were low birth weight (1500-2500g), while there were 8 children (9.52%) appropriate for age BW and no high BW for age patients (>4000 g). HG duration was 2.42+/-2.41 hours. In the group as a whole, hypoxic-ischemic encephalopathy (HIE) was found in 3 children (3.57%), infections in 22 (26.18%), respiratory distress syndrome (RDS) in 9 patients (10.62%), intracranial haemorrhage in 2 patients (2.38%). There were no inborn errors of metabolism. There were two deaths (2.38%).
    Conclusion: Neonatal HG is a significant factor in the overall neonatal mortality. HG can also cause severe invalidity. We found that infections, LBW and low gestational age were most commonly associated with neonatal HG. However the Spearman test showed weak direct correlation, without statistical significance. Neonatal HG requires complex and team interaction of prenatal and postnatal approaches to reduce the incidence of seizures, their consequences and the overall mortality. Special consideration is to be taken in measures that avoid neonatal infections, HIE, LBW and low gestational age. Further studies on a larger population are needed to fully understand and prevent the phenomenon of HG in newborns.
    MeSH term(s) Biomarkers/blood ; Birth Weight ; Blood Glucose/metabolism ; Communicable Diseases/epidemiology ; Comorbidity ; Female ; Gestational Age ; Humans ; Hypoglycemia/blood ; Hypoglycemia/epidemiology ; Hypoglycemia/mortality ; Hypoglycemia/therapy ; Incidence ; Infant, Low Birth Weight ; Infant, Newborn ; Infant, Premature ; Infant, Very Low Birth Weight ; Macedonia (Republic) ; Male ; Prognosis ; Risk Assessment ; Risk Factors ; Severity of Illness Index
    Chemical Substances Biomarkers ; Blood Glucose
    Language English
    Publishing date 2017-06-07
    Publishing country North Macedonia
    Document type Journal Article
    ZDB-ID 2743787-5
    ISSN 1857-8985 ; 1857-9345
    ISSN (online) 1857-8985
    ISSN 1857-9345
    DOI 10.1515/prilozi-2017-0013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Hypoglycaemia in the Newborn.

    Stomnaroska, Orhideja / Petkovska, Elizabeta / Ivanovska, Sanja / Jancevska, Snezana / Danilovski, Dragan

    Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)

    2017  Volume 38, Issue 2, Page(s) 79–84

    Abstract: Aim: Severe neonatal hypoglycaemia (HG) leads to neurologic damage, mental retardation, epilepsy, impaired cardiac performance and muscle weakness. The aim was to assess the frequency and severity of HG in a population of newborns.: Patients and ... ...

    Abstract Aim: Severe neonatal hypoglycaemia (HG) leads to neurologic damage, mental retardation, epilepsy, impaired cardiac performance and muscle weakness. The aim was to assess the frequency and severity of HG in a population of newborns.
    Patients and methods: We investigated 739 patients with neonatal hypoglycaemia (HG) (M:F=370:369) born at the University Clinic for Gynaecology and Obstetritics in Skopje in the period 2014-2016 and treated at the neonatal intensive care unit (NICU). 1416 babies were treated in the same period in NICU, and HG was observed in 52.18%. The birth weight was dominated by children with low birth weight: very low birth weight (VLBW)(<1500g) 253 children, (34,23%), low birth weight (1500-2500g) 402 (54.39%), appropriate for gestational age (AGA) 78(10.55%), and high birth weight (>4000g) 6 babies (0.81%). The gestational age was also dominated by children with low gestational age: gestational week (GW) 20-25 four children (0.54%), 26-30 GW 133 babies (17.99%), 31-35 GW472 (63.87%), and 36-40 GW130 neonates (17.59 %). 241 mothers (32.61%) have had an infection during pregnancy, 82 preeclampsia or eclampsia (11.09%), 20 diabetes mellitus (2.70%), 78 placental situations (placenta previa, abruption) (10.55%). In this study 47 babies (6.35%) with HG and co-morbidities died. There was a significant positive correlation between HG birth weight (p<0.01), gestational age (p<0.05), and the lowest Apgar score (p<0.01). Neonatal deaths were significantly correlated with GA (р>0,01), co-morbidities of the mothers (р>0,05) but not with the birth weight (р>0,05). In contrast, a significant positive correlation was found between convulsions and body weight (р<0.05). The lowest Apgar score was positively correlated with the gestational age (0.01), but not with the birth weight (0.05).
    Conclusion: Low birth weight, low gestational age, maternal risk factors, hypoxic-ischemic encephalopathy and neonatal infections are associated with HG and are a significant factor in overall neonatal mortality. Those results indicate that diminishing the frequency of the neonatal HG and the rates of neonatal mortality requires complex interaction of prenatal and postnatal interventions.
    MeSH term(s) Biomarkers/blood ; Birth Weight ; Blood Glucose/metabolism ; Comorbidity ; Female ; Gestational Age ; Health Status ; Hospital Mortality ; Humans ; Hyperglycemia/blood ; Hyperglycemia/diagnosis ; Hyperglycemia/epidemiology ; Hyperglycemia/therapy ; Infant ; Infant Mortality ; Infant, Low Birth Weight ; Infant, Newborn ; Intensive Care Units, Neonatal ; Macedonia (Republic)/epidemiology ; Male ; Premature Birth ; Prognosis ; Risk Assessment ; Risk Factors ; Severity of Illness Index ; Time Factors
    Chemical Substances Biomarkers ; Blood Glucose
    Language English
    Publishing date 2017-10-06
    Publishing country North Macedonia
    Document type Journal Article
    ZDB-ID 2743787-5
    ISSN 1857-8985 ; 1857-9345
    ISSN (online) 1857-8985
    ISSN 1857-9345
    DOI 10.1515/prilozi-2017-0025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Neonatal Hypoglycemia: A Continuing Debate in Definition and Management.

    Stomnaroska-Damcevski, Orhideja / Petkovska, Elizabeta / Jancevska, Snezana / Danilovski, Dragan

    Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)

    2016  Volume 36, Issue 3, Page(s) 91–97

    Abstract: Neonatal hypoglycemia (NH) is one of the most common abnormalities encountered in the newborn. Maintaining glucose homeostasis is one of the important physiological events during fetal-to-neonatal transition. Transient low blood glucose concentrations ... ...

    Abstract Neonatal hypoglycemia (NH) is one of the most common abnormalities encountered in the newborn. Maintaining glucose homeostasis is one of the important physiological events during fetal-to-neonatal transition. Transient low blood glucose concentrations are frequently encountered in the majority of healthy newborns and are the reflections of normal metabolic adaptation processes. Nevertheless, there is a great concern that prolonged or recurrent low blood glucose levels may result in long-term neurological and developmental consequences. Strikingly, it was demonstrated that the incidence and timing of low glucose concentrations in the groups most at risk for asymptomatic neonatal hypoglycemia, did not find association between repetitive low glucose concentrations and poor neurodevelopmental outcomes. On the contrary, NH due to hyperinsulinism is strongly associated with brain injury. Fundamental issue of great professional controversy is concerning the best manner to manage asymptomatic newborns NH. Both, overtreating NH and undertreating NH are poles with significant potential disadvantages. Therefore, NH is one of the most important issues in the day-to-day practice. This article appraises the critical questions of definition (widely accepted blood glucose concentration: < 2.6 mmol/l or 47 mg/dl), follow-up ad management of NH.
    MeSH term(s) Biomarkers/blood ; Blood Glucose/metabolism ; Diagnosis, Differential ; Humans ; Hypoglycemia/blood ; Hypoglycemia/classification ; Hypoglycemia/diagnosis ; Hypoglycemia/etiology ; Hypoglycemia/therapy ; Infant, Newborn ; Infant, Newborn, Diseases/blood ; Infant, Newborn, Diseases/classification ; Infant, Newborn, Diseases/diagnosis ; Infant, Newborn, Diseases/etiology ; Infant, Newborn, Diseases/therapy ; Predictive Value of Tests ; Risk Factors ; Time Factors ; Treatment Outcome
    Chemical Substances Biomarkers ; Blood Glucose
    Language English
    Publishing date 2016-06-23
    Publishing country North Macedonia
    Document type Journal Article ; Review
    ZDB-ID 2743787-5
    ISSN 1857-8985 ; 1857-9345
    ISSN (online) 1857-8985
    ISSN 1857-9345
    DOI 10.1515/prilozi-2015-0083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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