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Article: Single-cell analysis of bidirectional reprogramming between early embryonic states reveals mechanisms of differential lineage plasticities.

Garg, Vidur / Yang, Yang / Nowotschin, Sonja / Setty, Manu / Kuo, Ying-Yi / Sharma, Roshan / Polyzos, Alexander / Salataj, Eralda / Murphy, Dylan / Jang, Amy / Pe'er, Dana / Apostolou, Effie / Hadjantonakis, Anna-Katerina

bioRxiv : the preprint server for biology

2023  

Abstract: Two distinct fates, pluripotent epiblast (EPI) and primitive (extra-embryonic) endoderm (PrE), arise from common progenitor cells, the inner cell mass (ICM), in mammalian embryos. To study how these sister identities are forged, we leveraged embryonic ( ... ...

Abstract Two distinct fates, pluripotent epiblast (EPI) and primitive (extra-embryonic) endoderm (PrE), arise from common progenitor cells, the inner cell mass (ICM), in mammalian embryos. To study how these sister identities are forged, we leveraged embryonic (ES) and e
Language English
Publishing date 2023-03-29
Publishing country United States
Document type Preprint
DOI 10.1101/2023.03.28.534648
Database MEDical Literature Analysis and Retrieval System OnLINE

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