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  1. Article ; Online: Effect of PEEP decremental on respiratory mechanics, gasses exchanges, pulmonary regional ventilation, and hemodynamics in patients with SARS-Cov-2-associated acute respiratory distress syndrome.

    Bonny, Vincent / Janiak, Vincent / Spadaro, Savino / Pinna, Andrea / Demoule, Alexandre / Dres, Martin

    Critical care (London, England)

    2020  Volume 24, Issue 1, Page(s) 596

    MeSH term(s) COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/therapy ; Hemodynamics/physiology ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/therapy ; Positive-Pressure Respiration ; Pulmonary Gas Exchange/physiology ; Pulmonary Ventilation/physiology ; Respiratory Distress Syndrome/physiopathology ; Respiratory Distress Syndrome/therapy ; Respiratory Distress Syndrome/virology ; Respiratory Mechanics/physiology ; Treatment Outcome
    Keywords covid19
    Language English
    Publishing date 2020-10-06
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-020-03311-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Correction to: Effect of PEEP decremental on respiratory mechanics, gas exchange, pulmonary regional ventilation, and hemodynamics in patients with SARS-Cov-2-associated Acute Respiratory Distress Syndrome.

    Bonny, Vincent / Janiak, Vincent / Spadaro, Savino / Pinna, Andrea / Demoule, Alexandre / Dres, Martin

    Critical care (London, England)

    2020  Volume 24, Issue 1, Page(s) 675

    Abstract: An amendment to this paper has been published and can be accessed via the original article. ...

    Abstract An amendment to this paper has been published and can be accessed via the original article.
    Language English
    Publishing date 2020-12-04
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-020-03392-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Lung aeration estimated by chest electrical impedance tomography and lung ultrasound during extubation.

    Joussellin, Vincent / Bonny, Vincent / Spadaro, Savino / Clerc, Sébastien / Parfait, Mélodie / Ferioli, Martina / Sieye, Antonin / Jalil, Yorschua / Janiak, Vincent / Pinna, Andrea / Dres, Martin

    Annals of intensive care

    2023  Volume 13, Issue 1, Page(s) 91

    Abstract: Background: This study hypothesized that patients with extubation failure exhibit a loss of lung aeration and heterogeneity in air distribution, which could be monitored by chest EIT and lung ultrasound. Patients at risk of extubation failure were ... ...

    Abstract Background: This study hypothesized that patients with extubation failure exhibit a loss of lung aeration and heterogeneity in air distribution, which could be monitored by chest EIT and lung ultrasound. Patients at risk of extubation failure were included after a successful spontaneous breathing trial. Lung ultrasound [with calculation of lung ultrasound score (LUS)] and chest EIT [with calculation of the global inhomogeneity index, frontback center of ventilation (CoV), regional ventilation delay (RVD) and surface available for ventilation] were performed before extubation during pressure support ventilation (H0) and two hours after extubation during spontaneous breathing (H2). EIT was then repeated 6 h (H6) after extubation. EIT derived indices and LUS were compared between patients successfully extubated and patients with extubation failure.
    Results: 40 patients were included, of whom 12 (30%) failed extubation. Before extubation, when compared with patients with successful extubation, patients who failed extubation had a higher LUS (19 vs 10, p = 0.003) and a smaller surface available for ventilation (352 vs 406 pixels, p = 0.042). After extubation, GI index and LUS were higher in the extubation failure group, whereas the surface available for ventilation was lower. The RVD and the CoV were not different between groups.
    Conclusion: Before extubation, a loss of lung aeration was observed in patients who developed extubation failure afterwards. After extubation, this loss of lung aeration persisted and was associated with regional lung ventilation heterogeneity. Trial registration Clinical trials, NCT04180410, Registered 27 November 2019-prospectively registered, https://clinicaltrials.gov/ct2/show/NCT04180410 .
    Language English
    Publishing date 2023-09-26
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2617094-2
    ISSN 2110-5820
    ISSN 2110-5820
    DOI 10.1186/s13613-023-01180-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Effect of PEEP decremental on respiratory mechanics, gasses exchanges, pulmonary regional ventilation, and hemodynamics in patients with SARS-Cov-2-associated acute respiratory distress syndrome

    Bonny, Vincent / Janiak, Vincent / Spadaro, Savino / Pinna, Andrea / Demoule, Alexandre / Dres, Martin

    Crit Care

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #818127
    Database COVID19

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