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  1. AU="Janjua, Muhammad Burhan"
  2. AU="Sejal M. Patel"
  3. AU="Yuchen Wang"
  4. AU="Williams, Gareth"
  5. AU="Garber, John J"
  6. AU="Seon-Ah Cha"
  7. AU="Hill, Hanna"
  8. AU=Panteli Michalis
  9. AU="Rocha, Jorge"
  10. AU="Zheng, Yifeng"
  11. AU="Simmons, Benno I."
  12. AU="Rivest, Jean"
  13. AU=Tian Henghe
  14. AU=Rahal Elias A.
  15. AU=Denholt Charlotte
  16. AU=Neale Benjamin M
  17. AU="Simon, Krzysztof"
  18. AU="Srivastava, Abhay Krishna"
  19. AU=Serrano Luis A
  20. AU="D'Orio, Vincent"
  21. AU="Davies, Neville"
  22. AU="Wise, J.C."
  23. AU="Mazer, Benjamin L"
  24. AU="Vellore J. Karthikeyan"

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  1. Artikel: Concurrent Presence of Thoracolumbar Scoliosis and Chiari Malformation: Is Operative Risk Magnified?

    Naessig, Sara / Tretiakov, Peter / Patel, Karan / Ahmad, Waleed / Pierce, Katherine / Kummer, Nicholas / Joujon-Roche, Rachel / Imbo, Bailey / Williamson, Tyler / Krol, Oscar / Janjua, Muhammad Burhan / Vira, Shaleen / Diebo, Bassel / Sciubba, Daniel / Passias, Peter

    Asian spine journal

    2023  Band 17, Heft 4, Seite(n) 703–711

    Abstract: Study design: Retrospective review of Kids' Inpatient Database (KID).: Purpose: Identify the risks and complications associated with surgery in adolescents diagnosed with Chiari and scoliosis.: Overview of literature: Scoliosis is frequently ... ...

    Abstract Study design: Retrospective review of Kids' Inpatient Database (KID).
    Purpose: Identify the risks and complications associated with surgery in adolescents diagnosed with Chiari and scoliosis.
    Overview of literature: Scoliosis is frequently associated with Chiari malformation (CM). More specifically, reports have been made about this association with CM type I in the absence of syrinx status.
    Methods: The KID was used to identify all pediatric inpatients with CM and scoliosis. The patients were stratified into three groups: those with concomitant CM and scoliosis (CMS group), those with only CM (CM group), and those with only scoliosis (Sc group). Multivariate logistic regressions were used to assess association between surgical characteristics and diagnosis with complication rate.
    Results: A total of 90,707 spine patients were identified (61.8% Sc, 37% CM, 1.2% CMS). Sc patients were older, had a higher invasiveness score, and higher Charlson comorbidity index (all p<0.001). CMS patients had significantly higher rates of surgical decompression (36.7%). Sc patients had significantly higher rates of fusions (35.3%) and osteotomies (1.2%, all p<0.001). Controlling for age and invasiveness, postoperative complications were significantly associated with spine fusion surgery for Sc patients (odds ratio [OR], 1.8; p<0.05). Specifically, posterior spinal fusion in the thoracolumbar region had a greater risk of complications (OR, 4.9) than an anterior approach (OR, 3.6; all p<0.001). CM patients had a significant risk of complications when an osteotomy was performed as part of their surgery (OR, 2.9) and if a spinal fusion was concurrently performed (OR, 1.8; all p<0.05). Patients in the CMS cohort were significantly likely to develop postoperative complications if they underwent a spinal fusion from both anterior (OR, 2.5) and posterior approach (OR, 2.7; all p<0.001).
    Conclusions: Having concurrent scoliosis and CM increases operative risk for fusion surgeries despite approach. Being independently inflicted with scoliosis or Chiari leads to increased complication rate when paired with thoracolumbar fusion and osteotomies; respectively.
    Sprache Englisch
    Erscheinungsdatum 2023-05-25
    Erscheinungsland Korea (South)
    Dokumenttyp Journal Article
    ZDB-ID 2559763-2
    ISSN 1976-7846 ; 1976-1902
    ISSN (online) 1976-7846
    ISSN 1976-1902
    DOI 10.31616/asj.2022.0077
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Congenital Scoliosis of the Pediatric Cervical Spine: Characterization of a 17-Patient Operative Cohort.

    Toll, Brandon J / Samdani, Amer F / Amanullah, Amir A / Pahys, Joshua M / Janjua, Muhammad Burhan / Hwang, Steven W

    Journal of pediatric orthopedics

    2021  Band 41, Heft 3, Seite(n) e211–e216

    Abstract: Background: Congenital cervical scoliosis is rare, and there is a paucity of literature describing surgical outcomes. We report surgical outcomes in a 17-patient cohort with surgical correction for congenital cervical scoliosis and identify risk factors ...

    Abstract Background: Congenital cervical scoliosis is rare, and there is a paucity of literature describing surgical outcomes. We report surgical outcomes in a 17-patient cohort with surgical correction for congenital cervical scoliosis and identify risk factors associated with complications.
    Methods: Data were retrospectively collected from a single-center cohort of 17 consecutive patients (9 boys, 8 girls) receiving surgical deformity correction for congenital cervical scoliosis. The mean age at surgery was 7.1±3.4 years with an average follow-up of 3.6±1.1 years.
    Results: There were 24 operations performed on 17 patients, and 4 complications (17%) were reported in the series, including one each of pressure ulcer, asystole, vertebral artery injury, and pseudarthrosis. The mean preoperative major curve angle was 36±20 degrees, which improved to 24±14 degrees (P=0.02). The mean operative time was 8±2 hours with a mean estimated blood loss of 298±690 mL. Halo-gravity traction was used in 5 patients and 6 cases were staged with anterior/posterior procedures.
    Conclusions: Congenital scoliosis of the cervical spine is a complex process. The spinal deformity of this nature can be managed successfully with carefully planned and executed surgical correction.
    Level of evidence: Level IV-retrospective review.
    Mesh-Begriff(e) Cervical Vertebrae/diagnostic imaging ; Cervical Vertebrae/surgery ; Child ; Child, Preschool ; Diskectomy ; Female ; Humans ; Laminectomy ; Male ; Operative Time ; Postoperative Complications ; Radiography ; Retrospective Studies ; Scoliosis/congenital ; Scoliosis/diagnostic imaging ; Scoliosis/surgery ; Spinal Fusion ; Traction
    Sprache Englisch
    Erscheinungsdatum 2021-07-16
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 604642-3
    ISSN 1539-2570 ; 0271-6798
    ISSN (online) 1539-2570
    ISSN 0271-6798
    DOI 10.1097/BPO.0000000000001718
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: The Importance of Incorporating Proportional Alignment in Adult Cervical Deformity Corrections Relative to Regional and Global Alignment: Steps Toward Development of a Cervical-Specific Score.

    Passias, Peter G / Williamson, Tyler K / Pierce, Katherine E / Schoenfeld, Andrew J / Krol, Oscar / Imbo, Bailey / Joujon-Roche, Rachel / Tretiakov, Peter / Ahmad, Salman / Bennett-Caso, Claudia / Mir, Jamshaid / Dave, Pooja / McFarland, Kimberly / Owusu-Sarpong, Stephane / Lebovic, Jordan A / Janjua, Muhammad Burhan / de la Garza-Ramos, Rafael / Vira, Shaleen / Diebo, Bassel /
    Koller, Heiko / Protopsaltis, Themistocles S / Lafage, Renaud / Lafage, Virginie

    Spine

    2023  Band 49, Heft 2, Seite(n) 116–127

    Abstract: Study design/setting: Retrospective single-center study.: Background: The global alignment and proportion score is widely used in adult spinal deformity surgery. However, it is not specific to the parameters used in adult cervical deformity (ACD).: ...

    Abstract Study design/setting: Retrospective single-center study.
    Background: The global alignment and proportion score is widely used in adult spinal deformity surgery. However, it is not specific to the parameters used in adult cervical deformity (ACD).
    Purpose: Create a cervicothoracic alignment and proportion (CAP) score in patients with operative ACD.
    Methods: Patients with ACD with 2-year data were included. Parameters consisted of relative McGregor's Slope [RMGS = (MGS × 1.5)/0.9], relative cervical lordosis [RCL = CL - thoracic kyphosis (TK)], Cervical Lordosis Distribution Index (CLDI = C2 - Apex × 100/C2 - T2), relative pelvic version (RPV = sacral slope - pelvic incidence × 0.59 + 9), and a frailty factor (greater than 0.33). Cutoff points were chosen where the cross-tabulation of parameter subgroups reached a maximal rate of meeting the Optimal Outcome. The optimal outcome was defined as meeting Good Clinical Outcome criteria without the occurrence of distal junctional failure (DJF) or reoperation. CAP was scored between 0 and 13 and categorized accordingly: ≤3 (proportioned), 4-6 (moderately disproportioned), >6 (severely disproportioned). Multivariable logistic regression analysis determined the relationship between CAP categories, overall score, and development of distal junctional kyphosis (DJK), DJF, reoperation, and Optimal Outcome by 2 years.
    Results: One hundred five patients with operative ACD were included. Assessment of the 3-month CAP score found a mean of 5.2/13 possible points. 22.7% of patients were proportioned, 49.5% moderately disproportioned, and 27.8% severely disproportioned. DJK occurred in 34.5% and DJF in 8.7%, 20.0% underwent reoperation, and 55.7% achieved Optimal Outcome. Patients severely disproportioned in CAP had higher odds of DJK [OR: 6.0 (2.1-17.7); P =0.001], DJF [OR: 9.7 (1.8-51.8); P =0.008], reoperation [OR: 3.3 (1.9-10.6); P =0.011], and lower odds of meeting the optimal outcome [OR: 0.3 (0.1-0.7); P =0.007] by 2 years, while proportioned patients suffered zero occurrences of DJK or DJF.
    Conclusion: The regional alignment and proportion score is a method of analyzing the cervical spine relative to global alignment and demonstrates the importance of maintaining horizontal gaze, while also matching overall cervical and thoracolumbar alignment to limit complications and maximize clinical improvement.
    Mesh-Begriff(e) Adult ; Humans ; Lordosis/diagnostic imaging ; Lordosis/surgery ; Retrospective Studies ; Kyphosis/surgery ; Neck ; Cervical Vertebrae/diagnostic imaging ; Cervical Vertebrae/surgery
    Sprache Englisch
    Erscheinungsdatum 2023-10-05
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 752024-4
    ISSN 1528-1159 ; 0362-2436
    ISSN (online) 1528-1159
    ISSN 0362-2436
    DOI 10.1097/BRS.0000000000004843
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: The Effects of Global Alignment and Proportionality Scores on Postoperative Outcomes After Adult Spinal Deformity Correction.

    Passias, Peter G / Krol, Oscar / Owusu-Sarpong, Stephane / Tretiakov, Peter / Passfall, Lara / Kummer, Nicholas / Ani, Fares / Imbo, Bailey / Joujon-Roche, Rachel / Williamson, Tyler K / Sagoo, Navraj S / Vira, Shaleen / Schoenfeld, Andrew / De la Garza Ramos, Rafael / Janjua, Muhammad Burhan / Sciubba, Daniel / Diebo, Bassel G / Paulino, Carl / Smith, Justin /
    Lafage, Renaud / Lafage, Virginie

    Operative neurosurgery (Hagerstown, Md.)

    2023  Band 24, Heft 5, Seite(n) 533–541

    Abstract: Background: Recent studies have suggested achieving global alignment and proportionality (GAP) alignment may influence mechanical complications after adult spinal deformity (ASD) surgery.: Objective: To investigate the association between the GAP ... ...

    Abstract Background: Recent studies have suggested achieving global alignment and proportionality (GAP) alignment may influence mechanical complications after adult spinal deformity (ASD) surgery.
    Objective: To investigate the association between the GAP score and mechanical complications after ASD surgery.
    Methods: Patients with ASD with at least 5-level fusion to pelvis and minimum 2-year data were included. Multivariate analysis was used to find an association between proportioned (P), GAP-moderately disproportioned, and severely disproportioned (GAP-SD) states and mechanical complications (inclusive of proximal junctional kyphosis [PJK], proximal junctional failure [PJF], and implant-related complications [IC]). Severe sagittal deformity was defined by a "++" in the Scoliosis Research Society (SRS)-Schwab criteria for sagittal vertebral axis or pelvic incidence and lumbar lordosis.
    Results: Two hundred ninety patients with ASD were included. Controlling for age, Charlson comorbidity index, invasiveness and baseline deformity, and multivariate analysis showed no association of GAP-moderately disproportioned patients with proximal junctional kyphosis, PJF, or IC, while GAP-SD patients showed association with IC (odds ratio [OR]: 1.7, [1.1-3.3]; P = .043). Aligning in GAP-relative pelvic version led to lower likelihood of all 3 mechanical complications (all P < .04). In patients with severe sagittal deformity, GAP-SD was predictive of IC (OR: 2.1, [1.1-4.7]; P = .047), and in patients 70 years and older, GAP-SD was also predictive of PJF development (OR: 2.5, [1.1-14.9]; P = .045), while improving in GAP led to lower likelihood of PJF (OR: 0.2, [0.02-0.8]; P = .023).
    Conclusion: Severely disproportioned in GAP is associated with development of any IC and junctional failure specifically in older patients and those with severe baseline deformity. Therefore, incorporation of patient-specific factors into realignment goals may better strengthen the utility of this novel tool.
    Mesh-Begriff(e) Humans ; Adult ; Aged ; Retrospective Studies ; Spinal Fusion/adverse effects ; Spine/surgery ; Kyphosis/surgery ; Kyphosis/etiology ; Lordosis/surgery ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology
    Sprache Englisch
    Erscheinungsdatum 2023-01-23
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2767575-0
    ISSN 2332-4260 ; 2332-4252
    ISSN (online) 2332-4260
    ISSN 2332-4252
    DOI 10.1227/ons.0000000000000572
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Impact of Frailty on the Development of Proximal Junctional Failure: Does Frailty Supersede Achieving Optimal Realignment?

    Krol, Oscar / McFarland, Kimberly / Owusu-Sarpong, Stephane / Sagoo, Navraj / Williamson, Tyler / Joujon-Roche, Rachel / Tretiakov, Peter / Imbo, Bailey / Dave, Pooja / Mir, Jamshaid / Lebovic, Jordan / Onafowokan, Oluwatobi O / Schoenfeld, Andrew J / De la Garza Ramos, Rafael / Janjua, Muhammad Burhan / Sciubba, Daniel M / Diebo, Bassel G / Vira, Shaleen / Smith, Justin S /
    Lafage, Virginie / Lafage, Renaud / Passias, Peter G

    Spine

    2023  Band 48, Heft 19, Seite(n) 1348–1353

    Abstract: Background: Patients undergoing surgery for adult spinal deformity (ASD) are often elderly, frail, and at elevated risk of adverse events perioperatively, with proximal junctional failure (PJF) occurring relatively frequently. Currently, the specific ... ...

    Abstract Background: Patients undergoing surgery for adult spinal deformity (ASD) are often elderly, frail, and at elevated risk of adverse events perioperatively, with proximal junctional failure (PJF) occurring relatively frequently. Currently, the specific role of frailty in potentiating this outcome is poorly defined.
    Purpose: To determine if the benefits of optimal realignment in ASD, with respect to the development of PJF, can be offset by increasing frailty.
    Study design: Retrospective cohort.
    Materials and methods: Operative ASD patients (scoliosis >20°, SVA>5 cm, pelvic tilt>25°, or TK>60°) fused to the pelvis or below with available baseline and 2-year (2Y) radiographic and HRQL data were included. The Miller Frailty Index (FI) was used to stratify patients into 2 categories: Not Frail (FI <3) and Frail (>3). Proximal Junctional Failure (PJF) was defined using the Lafage criteria. "Matched" and "unmatched" refers to ideal age-adjusted alignment postoperatively. Multivariable regression determined the impact of frailty on the development of PJF.
    Results: Two hundred eighty-four ASD patients met inclusion criteria [62.2yrs±9.9, 81%F, BMI: 27.5 kg/m 2 ±5.3, ASD-FI: 3.4±1.5, Charlson Comorbidity Index (CCI): 1.7±1.6]. Forty-three percent of patients were characterized as Not Frail (NF) and 57% were characterized as Frail (F). PJF development was lower in the NF group compared with the F group (7% vs . 18%; P =0.002). F patients had 3.2 × higher risk of PJF development compared to NF patients (OR: 3.2, 95% CI: 1.3-7.3, P =0.009). Controlling for baseline factors, F unmatched patients had a higher degree of PJF (OR: 1.4, 95% CI:1.02-1.8, P =0.03); however, with prophylaxis, there was no increased risk. Adjusted analysis shows F patients, when matched postoperatively in PI-LL, had no significantly higher risk of PJF.
    Conclusions: An increasingly frail state is significantly associated with the development of PJF after corrective surgery for ASD. Optimal realignment may mitigate the impact of frailty on eventual PJF. Prophylaxis should be considered in frail patients who do not reach ideal alignment goals.
    Mesh-Begriff(e) Adult ; Humans ; Aged ; Kyphosis/surgery ; Retrospective Studies ; Frailty/epidemiology ; Postoperative Complications/etiology ; Spinal Fusion/methods ; Risk Factors
    Sprache Englisch
    Erscheinungsdatum 2023-05-12
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 752024-4
    ISSN 1528-1159 ; 0362-2436
    ISSN (online) 1528-1159
    ISSN 0362-2436
    DOI 10.1097/BRS.0000000000004719
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  6. Artikel ; Online: National Trends in the Prevalence, Treatment, and Associated Spinal Diagnoses Among Pediatric Spondylolysis Patients.

    Horn, Samantha R / Shepard, Nicholas / Poorman, Gregory W / Bortz, Cole A / Segreto, Frank A / Janjua, Muhammad Burhan / Diebo, Bassel G / Vira, Shaleen / Passias, Peter

    Bulletin of the Hospital for Joint Disease (2013)

    2019  Band 76, Heft 4, Seite(n) 246–251

    Abstract: Introduction: Spondylolysis is an increasingly common diagnoses for young individuals and presents with a wide range of pathological and clinical findings. Most patients are treated conservatively, and surgery is reserved for severe cases. This is a ... ...

    Abstract Introduction: Spondylolysis is an increasingly common diagnoses for young individuals and presents with a wide range of pathological and clinical findings. Most patients are treated conservatively, and surgery is reserved for severe cases. This is a populations study defining the incidence of spondylolysis in the Kids' Inpatient Database (KID) and assess trends in diagnoses, causes, and treatments.
    Methods: Retrospective analysis of the prospectively collected information in KID was performed for the years 2003 through 2012. Patients with a diagnosis of spondylolysis (ICD-9-CM 756.11) between the ages of 0 and 20 years in the KID were identified. Incidence of spondylolysis was established using KID-supplied hospital- and year-adjusted trend weights. Demographics including age, race, gender, and Charlson Comorbidity Index were assessed for all spondylolysis patients. Primary outcome measures were yearadjusted and hospital-adjusted incidence of spondylolysis. Secondary outcome measures were concurrent diagnoses and surgical details.
    Results: Six hundred and sixteen patients with a diagnosis of spondylolysis (329 with primary diagnosis) were identified (female: 53.8%; age: 15.27 ± 3.32 years). The incidence of spondylolysis is 7 per 100,000 patients nationally. Spondylolysis incidence has increased over time (p < 0.001) though the operative rate for spondylolysis has remained the same in the last decade (70% average, p = 0.52). The average CCI is 0.234, the average length of stay is 3.76 days and 92.4% of patients were discharged home. The etiology of the spondylolysis was trauma in 8.6% of patients (3.2% car crash, 1.9% pedestrian, 1.3% fall, 1.3% assault, 1.1% other transport, 1.0% sports, 0.3% motorcycle, 0.2% firearm, 0.2% bicycle; 1.9% reported multiple trauma etiologies). The most common concurrent diagnoses for all spondylolysis patients were spondylolisthesis (28%), idiopathic scoliosis (4.4%), cerebral palsy (1.9%), and spina bifida (1.8%). Four hundred and thirty patients with spondylolysis underwent surgical treatment and 40% of the surgically treated patients had spondylolisthesis. The rate of fusions was 54.9% fusions and 21% decompression, though the rate of fusions or decompressions being performed for spondylolysis has remained the same in the last decade (average fusion rate: 55%; average decompression rate: 18%; both p > 0.05). Levels fused and complications did not differ depending on whether or not decompression was performed (p > 0.05). The posterior-only approach was used in 62.2% of surgeries and were mostly 2 to 3 level procedures (63.5%). Perioperative complications occurred in 8.1% of patients, with the most common complications being device-related (2.3%), respiratory (1.5%), and digestive (1.5%).
    Conclusions: The national incidence of spondylolysis has increased over time, and the surgical rate and treatment techniques have remained constant. The most common concurrent diagnoses were idiopathic scoliosis, cerebral palsy, and spina bifida. Further work is required to determine the significance of these trends and associations.
    Mesh-Begriff(e) Adolescent ; Cerebral Palsy/epidemiology ; Child ; Comorbidity ; Decompression, Surgical/adverse effects ; Decompression, Surgical/methods ; Decompression, Surgical/statistics & numerical data ; Female ; Humans ; Incidence ; International Classification of Diseases ; Male ; Postoperative Complications/epidemiology ; Scoliosis/epidemiology ; Spinal Dysraphism/epidemiology ; Spinal Fusion/adverse effects ; Spinal Fusion/methods ; Spinal Fusion/statistics & numerical data ; Spondylolysis/diagnosis ; Spondylolysis/epidemiology ; Spondylolysis/surgery ; United States/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2019-09-26
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 390411-8
    ISSN 2328-5273 ; 1936-9727 ; 1936-9719 ; 0018-5647 ; 0883-9344 ; 2328-4633
    ISSN (online) 2328-5273 ; 1936-9727
    ISSN 1936-9719 ; 0018-5647 ; 0883-9344 ; 2328-4633
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Klippel-Feil: A constellation of diagnoses, a contemporary presentation, and recent national trends.

    Zhou, Peter L / Poorman, Gregory W / Wang, Charles / Pierce, Katherine E / Bortz, Cole A / Alas, Haddy / Brown, Avery E / Tishelman, Jared C / Janjua, Muhammad Burhan / Vasquez-Montes, Dennis / Moon, John / Horn, Samantha R / Segreto, Frank / Ihejirika, Yael U / Diebo, Bassel G / Passias, Peter Gust

    Journal of craniovertebral junction & spine

    2019  Band 10, Heft 3, Seite(n) 133–138

    Abstract: Background: Klippel-Feil syndrome (KFS) includes craniocervical anomalies, low posterior hairline, and brevicollis, with limited cervical range of motion; however, there remains no consensus on inheritance pattern. This study defines incidence, ... ...

    Abstract Background: Klippel-Feil syndrome (KFS) includes craniocervical anomalies, low posterior hairline, and brevicollis, with limited cervical range of motion; however, there remains no consensus on inheritance pattern. This study defines incidence, characterizes concurrent diagnoses, and examines trends in the presentation and management of KFS.
    Methods: This was a retrospective review of the Kid's Inpatient Database (KID) for KFSpatients aged 0-20 years from 2003 to 2012. Incidence was established using KID-supplied year and hospital-trend weights. Demographics and secondary diagnoses associated with KFS were evaluated. Comorbidities, anomalies, and procedure type trends from 2003 to 2012 were assessed for likelihood to increase among the years studied using ANOVA tests.
    Results: Eight hundred and fifty-eight KFS diagnoses (age: 9.49 years; 51.1% females) and 475 patients with congenital fusion (CF) (age: 8.33 years; 50.3% females) were analyzed. We identified an incidence rate of 1/21,587 discharges. Only 6.36% of KFS patients were diagnosed with Sprengel's deformity; 1.44% with congenital fusion. About 19.1% of KFS patients presented with another spinal abnormality and 34.0% presented with another neuromuscular anomaly. About 36.51% of KFS patients were diagnosed with a nonspinal or nonmusculoskeletal anomaly, with the most prevalent anomalies being of cardiac origin (12.95%). About 7.34% of KFS patients underwent anterior fusions, whereas 6.64% of KFS patients underwent posterior fusions. The average number of levels operated on was 4.99 with 8.28% receiving decompressions. Interbody devices were used in 2.45% of cases. The rate of fusions with <3 levels (7.46%) was comparable to that of 3 levels or greater (7.81%).
    Conclusions: KFS patients were more likely to have other spinal abnormalities (19.1%) and nonnervous system abnormalities (13.63%). Compared to congenital fusions, KFS patients were more likely to have congenital abnormalities such as Sprengel's deformity. KFS patients are increasingly being treated with spinal fusion.
    Level of evidence: III.
    Sprache Englisch
    Erscheinungsdatum 2019-04-01
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2573344-8
    ISSN 0976-9285 ; 0974-8237
    ISSN (online) 0976-9285
    ISSN 0974-8237
    DOI 10.4103/jcvjs.JCVJS_65_19
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: A cost benefit analysis of increasing surgical technology in lumbar spine fusion.

    Passias, Peter G / Brown, Avery E / Alas, Haddy / Bortz, Cole A / Pierce, Katherine E / Hassanzadeh, Hamid / Labaran, Lawal A / Puvanesarajah, Varun / Vasquez-Montes, Dennis / Wang, Erik / Ihejirika, Rivka C / Diebo, Bassel G / Lafage, Virginie / Lafage, Renaud / Sciubba, Daniel M / Janjua, Muhammad Burhan / Protopsaltis, Themistocles S / Buckland, Aaron J / Gerling, Michael C

    The spine journal : official journal of the North American Spine Society

    2020  Band 21, Heft 2, Seite(n) 193–201

    Abstract: Background context: Numerous advances have been made in the field of spine fusion, such as minimally invasive (MIS) or robotic-assisted spine surgery. However, it is unknown how these advances have impacted the cost of care.: Purpose: Compare the ... ...

    Abstract Background context: Numerous advances have been made in the field of spine fusion, such as minimally invasive (MIS) or robotic-assisted spine surgery. However, it is unknown how these advances have impacted the cost of care.
    Purpose: Compare the economic outcomes of lumbar spine fusion between open, MIS, and robot-assisted surgery patients.
    Study design/setting: Retrospective review of a single center spine surgery database.
    Patient sample: Three hundred sixty propensity matched patients.
    Outcome measures: Costs, EuroQol-5D (EQ5D), cost per quality adjusted life years (QALY).
    Methods: Inclusion criteria: surgical patients >18 years undergoing lumbar fusion surgery. Patients were categorized into 3 groups based on procedure type: open, MIS, or robotic. Open patients undergoing poster spinal fusion were considered as the control group. MIS patients included those undergoing transforaminal or lateral lumbar interbody fusion with percutaneous screws. Robotic patients were those undergoing robot-assisted fusion. Propensity score matching was performed between all groups for the number of levels fused. Costs were calculated using the PearlDiver database, which reflects both private insurance and Medicare reimbursement claims for ICD-9 codes. For robotic cases, costs were reflective of operational fees and initial purchase cost. Complications and comorbidities and major complications and comorbidities were assessed according to CMS.gov manual definitions. QALYs and cost per QALY were calculated using a 3% discount rate to account for residual decline to life expectancy (78.7 years). Costs per QALY were calculated for both 1 year and life expectancy, assuming no loss of benefit. A 10,000 trial Monte Carlo simulation with probabilistic sensitivity analysis (PSA) assessed our model parameters and costs.
    Results: Three hundred sixty propensity matched patients (120 open, 120 MIS, 120 robotic) met inclusion criteria. Descriptive statistics for the cohort were: age 58.8±13.5, 50% women, BMI 29.4±6.3, operative time 294.4±119.0, LOS 4.56±3.31 days, estimated blood loss 515.9±670.0 cc, and 2.3±2.2 average levels fused. Rates of post-op complications were significantly higher in robotic cases versus open and MIS (43% vs. 21% and 22% for open and MIS, p<.05). However, revision rates were comparable between all groups (3% open, 3% MIS, 5% robotic, p>.05). After factoring in complications, revisions, and purchasing and operating fees, the costs of robotic cases was significantly higher than both open and MIS surgery ($60,047.01 vs. $42,538.98 open and $41,471.21 MIS). In a subanalysis of 42 patients with baseline (BL) and 1Y EQ5D data, the cost per QALY at 1Y for open, MIS, and robot-assisted cases was $296,624.48, $115,911.69, and $592,734.30. If utility gained was sustained to life expectancy, the cost per QALY was $14,905.75, $5,824.71, $29,785.64 for open, MIS, and robot-assisted cases. Results of the PSA were consistent with MIS surgery having the most incremental cost effectiveness when compared to open and robotic surgery.
    Conclusions: Numerous advances have been made in the field of spine surgery, however, there has been limited discussion of the effect these advances have on economic outcomes. When matched for levels fused, robot-assisted surgery patients had significantly higher rates of complications and 30% higher costs of surgery compared to minimally invasive and open spine surgery patients. While 1 year economic outcomes were not optimal for robotic surgery cases, the projected costs per QALYs at life expectancy were well below established acceptable thresholds. The above findings may be reflective of an educational learning curve and emerging surgical technologies undergoing progressive refinement.
    Mesh-Begriff(e) Aged ; Cost-Benefit Analysis ; Female ; Humans ; Lumbar Vertebrae/surgery ; Male ; Medicare ; Middle Aged ; Minimally Invasive Surgical Procedures ; Retrospective Studies ; Spinal Fusion ; Technology ; Treatment Outcome ; United States
    Sprache Englisch
    Erscheinungsdatum 2020-10-15
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2037072-6
    ISSN 1878-1632 ; 1529-9430
    ISSN (online) 1878-1632
    ISSN 1529-9430
    DOI 10.1016/j.spinee.2020.10.012
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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