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  1. Book: Lithium affects Life History Traits in the Model Organism Drosophila melanogaster

    Jans, Katharina

    (Berichte aus der Ernährungswissenschaft)

    2023  

    Abstract: Lithium is a trace element in human nutrition. Although there are indications of a possible essential function of the alkali metal in the animal kingdom, none has yet been sufficiently defined and proven, thus leaving lithium to be categorized as ... ...

    Series title Berichte aus der Ernährungswissenschaft
    Abstract Lithium is a trace element in human nutrition. Although there are indications of a possible essential function of the alkali metal in the animal kingdom, none has yet been sufficiently defined and proven, thus leaving lithium to be categorized as potentially essential. This work focuses on the impact of dietary lithium on two competitive life-history traits, longevity and fecundity, in the model organism Drosophila melanogaster, with respect to lithium’s potential of modulating glycogen synth...
    Keywords Food Science ; Drosophila melanogaster ; Lithium
    Language English
    Size 224 p.
    Edition 1
    Publisher Shaker Verlag
    Document type Book
    Note Aktuell_PDA Manuell_26
    Format 148 x 210
    ISBN 9783844093223 ; 3844093222
    Database PDA

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  2. Article ; Online: Drosophila melanogaster

    Jans, Katharina / Lüersen, Kai / Rimbach, Gerald

    International journal of molecular sciences

    2021  Volume 22, Issue 21

    Abstract: The fruit ... ...

    Abstract The fruit fly
    MeSH term(s) Animals ; Boron/metabolism ; Drosophila melanogaster ; Lithium/metabolism ; Models, Animal ; Trace Elements/metabolism
    Chemical Substances Trace Elements ; Lithium (9FN79X2M3F) ; Boron (N9E3X5056Q)
    Language English
    Publishing date 2021-10-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms222111710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Dietary lithium stimulates female fecundity in Drosophila melanogaster.

    Jans, Katharina / Lüersen, Kai / von Frieling, Jakob / Roeder, Thomas / Rimbach, Gerald

    BioFactors (Oxford, England)

    2023  Volume 50, Issue 2, Page(s) 326–346

    Abstract: The trace element lithium exerts a versatile bioactivity in humans, to some extend overlapping with in vivo findings in the model organism Drosophila melanogaster. A potentially essential function of lithium in reproduction has been suggested since the ... ...

    Abstract The trace element lithium exerts a versatile bioactivity in humans, to some extend overlapping with in vivo findings in the model organism Drosophila melanogaster. A potentially essential function of lithium in reproduction has been suggested since the 1980s and multiple studies have since been published postulating a regulatory role of lithium in female gametogenesis. However, the impact of lithium on fruit fly egg production has not been at the center of attention to date. In the present study, we report that dietary lithium (0.1-5.0 mM LiCl) substantially improved life time egg production in D. melanogaster w
    MeSH term(s) Humans ; Animals ; Female ; Drosophila melanogaster/genetics ; Drosophila melanogaster/metabolism ; Lithium/pharmacology ; Lithium/metabolism ; Trace Elements/metabolism ; Reproduction ; Fertility ; Insulin/metabolism
    Chemical Substances Lithium (9FN79X2M3F) ; Trace Elements ; Insulin
    Language English
    Publishing date 2023-09-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 59230-4
    ISSN 1872-8081 ; 0951-6433
    ISSN (online) 1872-8081
    ISSN 0951-6433
    DOI 10.1002/biof.2007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Boron Contents of German Mineral and Medicinal Waters and Their Bioavailability in Drosophila melanogaster and Humans

    Seidel, Ulrike / Haegele, Franziska A. / Baumhof, Elena / Jans, Katharina / Seidler, Yvonne / Kremer, Daan / Bakker, Stephan J. L. / Birringer, Marc / Lüersen, Kai / Bosy‐Westphal, Anja / Rimbach, Gerald

    Molecular nutrition & food research. 2021 Aug., v. 65, no. 15

    2021  

    Abstract: SCOPE: Boron is a trace element that naturally occurs in soil, making mineral and medicinal water important contributors to overall intake. Thus, in a systematic screening, the mean boron concentrations of 381 German mineral and medicinal waters are ... ...

    Abstract SCOPE: Boron is a trace element that naturally occurs in soil, making mineral and medicinal water important contributors to overall intake. Thus, in a systematic screening, the mean boron concentrations of 381 German mineral and medicinal waters are determined. METHODS AND RESULTS: Boron concentrations in mineral and medicinal waters are analyzed by inductively coupled mass spectrometry (ICP‐MS). Highest boron values find in waters from the southwest of Germany. The boron content of the waters is positively correlated with the concentration of most other analyzed bulk elements, including calcium, potassium, magnesium, and sodium. Mineral waters with either low (7.9 µg L⁻¹), medium (113.9 µg L⁻¹), or high (2193.3 µg L⁻¹) boron content are chosen for boron exposure experiments in fruit flies (Drosophila melanogaster) and humans. In flies, boron‐rich mineral water significantly increases boron accumulation, with the accumulation predominantly occurring in the exoskeleton. In humans, serum boron and 24‐h urinary boron excretion significantly increase only in response to the intake of boron‐rich mineral water. CONCLUSION: Overall, the current data demonstrate that mineral and medicinal waters vary substantially in the content of boron and that boron‐rich mineral water can be used to elevate the boron status, both in flies and humans.
    Keywords Drosophila melanogaster ; bioavailability ; blood serum ; boron ; calcium ; excretion ; exoskeleton ; food research ; fruits ; magnesium ; mass spectrometry ; mineral water ; nutrition ; potassium ; sodium ; soil ; Germany
    Language English
    Dates of publication 2021-08
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 2160372-8
    ISSN 1613-4133 ; 1613-4125
    ISSN (online) 1613-4133
    ISSN 1613-4125
    DOI 10.1002/mnfr.202100345
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: Lithium Content of 160 Beverages and Its Impact on Lithium Status in

    Seidel, Ulrike / Jans, Katharina / Hommen, Niklas / Ipharraguerre, Ignacio R / Lüersen, Kai / Birringer, Marc / Rimbach, Gerald

    Foods (Basel, Switzerland)

    2020  Volume 9, Issue 6

    Abstract: Lithium (Li) is an important micronutrient in human nutrition, although its exact molecular function as a potential essential trace element has not yet been fully elucidated. It has been previously shown that several mineral waters are rich and highly ... ...

    Abstract Lithium (Li) is an important micronutrient in human nutrition, although its exact molecular function as a potential essential trace element has not yet been fully elucidated. It has been previously shown that several mineral waters are rich and highly bioavailable sources of Li for human consumption. Nevertheless, little is known about the extent in which other beverages contribute to the dietary Li supply. To this end, the Li content of 160 different beverages comprising wine and beer, soft and energy drinks and tea and coffee infusions was analysed by inductively coupled plasma mass spectrometry (ICP-MS). Furthermore, a feeding study in
    Language English
    Publishing date 2020-06-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods9060795
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Boron Contents of German Mineral and Medicinal Waters and Their Bioavailability in Drosophila melanogaster and Humans.

    Seidel, Ulrike / Haegele, Franziska A / Baumhof, Elena / Jans, Katharina / Seidler, Yvonne / Kremer, Daan / Bakker, Stephan J L / Birringer, Marc / Lüersen, Kai / Bosy-Westphal, Anja / Rimbach, Gerald

    Molecular nutrition & food research

    2021  Volume 65, Issue 15, Page(s) e2100345

    Abstract: Scope: Boron is a trace element that naturally occurs in soil, making mineral and medicinal water important contributors to overall intake. Thus, in a systematic screening, the mean boron concentrations of 381 German mineral and medicinal waters are ... ...

    Abstract Scope: Boron is a trace element that naturally occurs in soil, making mineral and medicinal water important contributors to overall intake. Thus, in a systematic screening, the mean boron concentrations of 381 German mineral and medicinal waters are determined.
    Methods and results: Boron concentrations in mineral and medicinal waters are analyzed by inductively coupled mass spectrometry (ICP-MS). Highest boron values find in waters from the southwest of Germany. The boron content of the waters is positively correlated with the concentration of most other analyzed bulk elements, including calcium, potassium, magnesium, and sodium. Mineral waters with either low (7.9 µg L
    Conclusion: Overall, the current data demonstrate that mineral and medicinal waters vary substantially in the content of boron and that boron-rich mineral water can be used to elevate the boron status, both in flies and humans.
    MeSH term(s) Adult ; Aluminum/analysis ; Animals ; Biological Availability ; Boron/analysis ; Boron/blood ; Boron/pharmacokinetics ; Boron/urine ; Dietary Supplements ; Drosophila melanogaster/drug effects ; Fresh Water/analysis ; Fresh Water/chemistry ; Germany ; Healthy Volunteers ; Humans ; Lithium/analysis ; Male ; Mineral Waters/analysis ; Trace Elements/analysis
    Chemical Substances Mineral Waters ; Trace Elements ; Lithium (9FN79X2M3F) ; Aluminum (CPD4NFA903) ; Boron (N9E3X5056Q)
    Language English
    Publishing date 2021-06-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2160372-8
    ISSN 1613-4133 ; 1613-4125
    ISSN (online) 1613-4133
    ISSN 1613-4125
    DOI 10.1002/mnfr.202100345
    Database MEDical Literature Analysis and Retrieval System OnLINE

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