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  1. Article ; Online: Hot isostatic pressing as an alternative thermo-mechanical treatment for metallic full-arch implant-supported frameworks obtained by additive and subtractive manufacturing technology: Vertical and horizontal fit, screw removal torque, and stress analysis.

    Barbin, Thaís / Borges, Guilherme Almeida / Jardini, André Luiz / Mesquita, Marcelo Ferraz

    Journal of prosthodontics : official journal of the American College of Prosthodontists

    2024  

    Abstract: Purpose: To assess vertical and horizontal fit, screw removal torque, and stress analysis (considered biomechanical aspects) of full-arch implant frameworks manufactured in Ti-6Al-4V through milling, and additive manufacturing Direct Metal Laser ... ...

    Abstract Purpose: To assess vertical and horizontal fit, screw removal torque, and stress analysis (considered biomechanical aspects) of full-arch implant frameworks manufactured in Ti-6Al-4V through milling, and additive manufacturing Direct Metal Laser Sintering (DMLS) and Electron Beam Melting (EBM), and the effect of the thermo-mechanical treatment Hot Isostatic Pressing (HIP) as a post-treatment after manufacturing.
    Material and methods: Maxillary full-arch implant frameworks were made by milling, DMLS, and EBM. The biomechanical assessments were screw removal torque, strain-gauge analyses, and vertical and horizontal marginal fits. The vertical fit was assessed by the single-screw test and with all screws tightened. All frameworks were submitted to a standardized HIP cycle (920°C, 1000 bar pressure, 2 h), and the tests were repeated (α = 0.05).
    Results: At the initial time, milled frameworks presented higher screw removal torque values, and DMLS and EBM frameworks presented lower levels of strain. Using the single-screw test, milled and DMLS frameworks presented higher vertical fit values, and with all screws tightened and horizontally, higher fit values were found for milled frameworks, followed by DMLS and EBM. After HIP, milling and EBM frameworks presented higher screw removal torque values; the lowest strain values were found for EBM. Using the single-screw test, milled and DMLS frameworks presented higher vertical fit values, and with all screws tightened and horizontally no differences were found.
    Conclusions: DMLS and EBM full-arch frameworks presented adequate values of screw removal torque, strain, and marginal fit, although the worst values of marginal fit were found for EBM frameworks. The HIP cycle enhanced the screw removal torque of milled and EBM frameworks and reduced the strain values of milled frameworks. The HIP represents a reliable post-treatment for Ti-6Al-4V dental prostheses produced by milling and EBM technologies.
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1197213-0
    ISSN 1532-849X ; 1059-941X
    ISSN (online) 1532-849X
    ISSN 1059-941X
    DOI 10.1111/jopr.13842
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Biological performance of a bioabsorbable Poly (L-Lactic Acid) produced in polymerization unit:

    Xavier, Mariana / Farez, Nayla / Salvatierra, Paola Luciana / Jardini, Andre Luiz / Kharmandayan, Paulo / Feldman, Sara

    F1000Research

    2021  Volume 10, Page(s) 1275

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Absorbable Implants ; Animals ; Female ; Lactic Acid ; Polyesters ; Polymerization ; Rabbits
    Chemical Substances Polyesters ; Lactic Acid (33X04XA5AT) ; poly(lactide) (459TN2L5F5)
    Language English
    Publishing date 2021-12-13
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2699932-8
    ISSN 2046-1402 ; 2046-1402
    ISSN (online) 2046-1402
    ISSN 2046-1402
    DOI 10.12688/f1000research.73754.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Extracellular matrix-derived and low-cost proteins to improve polyurethane-based scaffolds for vascular grafts.

    Rodrigues, Isabella C P / Lopes, Éder S N / Pereira, Karina D / Huber, Stephany C / Jardini, André Luiz / Annichino-Bizzacchi, Joyce M / Luchessi, Augusto D / Gabriel, Laís P

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 5230

    Abstract: Vascular graft surgeries are often conducted in trauma cases, which has increased the demand for scaffolds with good biocompatibility profiles. Biodegradable scaffolds resembling the extracellular matrix (ECM) of blood vessels are promising vascular ... ...

    Abstract Vascular graft surgeries are often conducted in trauma cases, which has increased the demand for scaffolds with good biocompatibility profiles. Biodegradable scaffolds resembling the extracellular matrix (ECM) of blood vessels are promising vascular graft materials. In the present study, polyurethane (PU) was blended with ECM proteins collagen and elastin (Col-El) and gelatin (Gel) to produce fibrous scaffolds by using the rotary jet spinning (RJS) technique, and their effects on in vitro properties were evaluated. Morphological and structural characterization of the scaffolds was performed using scanning electron microscopy (SEM) and atomic force microscopy (AFM). Micrometric fibers with nanometric rugosity were obtained. Col-El and Gel reduced the mechanical strength and increased the hydrophilicity and degradation rates of PU. No platelet adhesion or activation was observed. The addition of proteins to the PU blend increased the viability, adhesion, and proliferation of human umbilical vein endothelial cells (HUVECs). Therefore, PU-Col-El and PU-Gel scaffolds are promising biomaterials for vascular graft applications.
    MeSH term(s) Bioprosthesis ; Blood Vessel Prosthesis ; Extracellular Matrix ; Human Umbilical Vein Endothelial Cells ; Humans ; Polyurethanes/chemistry ; Polyurethanes/pharmacology
    Chemical Substances Polyurethanes
    Language English
    Publishing date 2022-03-28
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-09040-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Cardiac tissue engineering: current state-of-the-art materials, cells and tissue formation.

    Rodrigues, Isabella Caroline Pereira / Kaasi, Andreas / Maciel Filho, Rubens / Jardini, André Luiz / Gabriel, Laís Pellizzer

    Einstein (Sao Paulo, Brazil)

    2018  Volume 16, Issue 3, Page(s) eRB4538

    Abstract: Cardiovascular diseases are the major cause of death worldwide. The heart has limited capacity of regeneration, therefore, transplantation is the only solution in some cases despite presenting many disadvantages. Tissue engineering has been considered ... ...

    Abstract Cardiovascular diseases are the major cause of death worldwide. The heart has limited capacity of regeneration, therefore, transplantation is the only solution in some cases despite presenting many disadvantages. Tissue engineering has been considered the ideal strategy for regenerative medicine in cardiology. It is an interdisciplinary field combining many techniques that aim to maintain, regenerate or replace a tissue or organ. The main approach of cardiac tissue engineering is to create cardiac grafts, either whole heart substitutes or tissues that can be efficiently implanted in the organism, regenerating the tissue and giving rise to a fully functional heart, without causing side effects, such as immunogenicity. In this review, we systematically present and compare the techniques that have drawn the most attention in this field and that generally have focused on four important issues: the scaffold material selection, the scaffold material production, cellular selection and in vitro cell culture. Many studies used several techniques that are herein presented, including biopolymers, decellularization and bioreactors, and made significant advances, either seeking a graft or an entire bioartificial heart. However, much work remains to better understand and improve existing techniques, to develop robust, efficient and efficacious methods.
    MeSH term(s) Biopolymers ; Bioreactors ; Cell Culture Techniques/methods ; Heart Transplantation/methods ; Heart Transplantation/trends ; Humans ; Myocardium/cytology ; Tissue Engineering/methods ; Tissue Engineering/trends ; Tissue Scaffolds
    Chemical Substances Biopolymers
    Language Portuguese
    Publishing date 2018-09-21
    Publishing country Brazil
    Document type Journal Article ; Review
    ZDB-ID 2418293-X
    ISSN 2317-6385 ; 1679-4508
    ISSN (online) 2317-6385
    ISSN 1679-4508
    DOI 10.1590/S1679-45082018RB4538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: An assessment of biomedical CoCrMo alloy fabricated by direct metal laser sintering technique for implant applications.

    de Castro Girão, Daniel / Béreš, Miloslav / Jardini, André Luiz / Filho, Rubens Maciel / Silva, Cleiton Carvalho / de Siervo, Abner / Gomes de Abreu, Hamilton Ferreira / Araújo, Walney Silva

    Materials science & engineering. C, Materials for biological applications

    2019  Volume 107, Page(s) 110305

    Abstract: CoCrMo alloys have been used for several decades in implantable devices due to their favourable mechanical properties, low wear rate in addition to good biocompatibility and high corrosion resistance. These alloys are conventionally produced via casting ... ...

    Abstract CoCrMo alloys have been used for several decades in implantable devices due to their favourable mechanical properties, low wear rate in addition to good biocompatibility and high corrosion resistance. These alloys are conventionally produced via casting and/or forging route, however additive manufacturing techniques being recently employed in their fabrication. In this work, CoCrMo samples were produced by direct metal laser sintering additive manufacturing process. The microstructure and surface composition were examined employing scanning electron microscopy, X-ray diffraction and X-ray photoelectron spectroscopy (XPS). The corrosion resistance was measured in 0.14 M sodium chloride solution and in phosphate buffered solution (PBS) both with and without addition of albumin at pH 7.4 and 37 °C. For this, potentiodynamic tests in addition to electrochemical impedance spectroscopy were employed. The studied CoCrMo alloy exhibits a good corrosion resistance in solutions tested being the highest in PBS solution without albumin addition. The XPS analysis showed that the passive film composition and its thickness are not modified by the adsorbed layer. Microstructural analysis revealed occurrence of strain-induced martensitic transformation.
    MeSH term(s) Biocompatible Materials/chemistry ; Corrosion ; Lasers ; Materials Testing ; Vitallium/chemistry
    Chemical Substances Biocompatible Materials ; Vitallium (12629-02-6)
    Language English
    Publishing date 2019-10-21
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2012160-X
    ISSN 1873-0191 ; 0928-4931
    ISSN (online) 1873-0191
    ISSN 0928-4931
    DOI 10.1016/j.msec.2019.110305
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  6. Article: Osseointegration Improvement of Co-Cr-Mo Alloy Produced by Additive Manufacturing.

    Iatecola, Amilton / Longhitano, Guilherme Arthur / Antunes, Luiz Henrique Martinez / Jardini, André Luiz / Miguel, Emilio de Castro / Béreš, Miloslav / Lambert, Carlos Salles / Andrade, Tiago Neves / Buchaim, Rogério Leone / Buchaim, Daniela Vieira / Pomini, Karina Torres / Dias, Jefferson Aparecido / Spressão, Daniele Raineri Mesquita Serva / Felix, Marcílio / Cardoso, Guinea Brasil Camargo / da Cunha, Marcelo Rodrigues

    Pharmaceutics

    2021  Volume 13, Issue 5

    Abstract: Cobalt-base alloys (Co-Cr-Mo) are widely employed in dentistry and orthopedic implants due to their biocompatibility, high mechanical strength and wear resistance. The osseointegration of implants can be improved by surface modification techniques. ... ...

    Abstract Cobalt-base alloys (Co-Cr-Mo) are widely employed in dentistry and orthopedic implants due to their biocompatibility, high mechanical strength and wear resistance. The osseointegration of implants can be improved by surface modification techniques. However, complex geometries obtained by additive manufacturing (AM) limits the efficiency of mechanical-based surface modification techniques. Therefore, plasma immersion ion implantation (PIII) is the best alternative, creating nanotopography even in complex structures. In the present study, we report the osseointegration results in three conditions of the additively manufactured Co-Cr-Mo alloy: (i) as-built, (ii) after PIII, and (iii) coated with titanium (Ti) followed by PIII. The metallic samples were designed with a solid half and a porous half to observe the bone ingrowth in different surfaces. Our results revealed that all conditions presented cortical bone formation. The titanium-coated sample exhibited the best biomechanical results, which was attributed to the higher bone ingrowth percentage with almost all medullary canals filled with neoformed bone and the pores of the implant filled and surrounded by bone ingrowth. It was concluded that the metal alloys produced for AM are biocompatible and stimulate bone neoformation, especially when the Co-28Cr-6Mo alloy with a Ti-coated surface, nanostructured and anodized by PIII is used, whose technology has been shown to increase the osseointegration capacity of this implant.
    Language English
    Publishing date 2021-05-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics13050724
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  7. Article ; Online: Cranial reconstruction: 3D biomodel and custom-built implant created using additive manufacturing.

    Jardini, André Luiz / Larosa, Maria Aparecida / Maciel Filho, Rubens / Zavaglia, Cecília Amélia de Carvalho / Bernardes, Luis Fernando / Lambert, Carlos Salles / Calderoni, Davi Reis / Kharmandayan, Paulo

    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery

    2014  Volume 42, Issue 8, Page(s) 1877–1884

    Abstract: Additive manufacturing (AM) technology from engineering has helped to achieve several advances in the medical field, particularly as far as fabrication of implants is concerned. The use of AM has made it possible to carry out surgical planning and ... ...

    Abstract Additive manufacturing (AM) technology from engineering has helped to achieve several advances in the medical field, particularly as far as fabrication of implants is concerned. The use of AM has made it possible to carry out surgical planning and simulation using a three-dimensional physical model which accurately represents the patient's anatomy. AM technology enables the production of models and implants directly from a 3D virtual model, facilitating surgical procedures and reducing risks. Furthermore, AM has been used to produce implants designed for individual patients in areas of medicine such as craniomaxillofacial surgery, with optimal size, shape and mechanical properties. This work presents AM technologies which were applied to design and fabricate a biomodel and customized implant for the surgical reconstruction of a large cranial defect. A series of computed tomography data was obtained and software was used to extract the cranial geometry. The protocol presented was used to create an anatomic biomodel of the bone defect for surgical planning and, finally, the design and manufacture of the patient-specific implant.
    MeSH term(s) Alloys/chemistry ; Biocompatible Materials/chemistry ; Biomedical Engineering ; Biomedical Technology ; Computer Simulation ; Computer-Aided Design ; Decompressive Craniectomy/adverse effects ; Frontal Bone/injuries ; Frontal Bone/surgery ; Humans ; Image Processing, Computer-Assisted/methods ; Imaging, Three-Dimensional/methods ; Male ; Models, Anatomic ; Patient Care Planning ; Printing, Three-Dimensional ; Prostheses and Implants ; Prosthesis Design ; Reconstructive Surgical Procedures/methods ; Skull/surgery ; Software ; Surgery, Computer-Assisted ; Titanium/chemistry ; Tomography, X-Ray Computed/methods ; User-Computer Interface ; Young Adult
    Chemical Substances Alloys ; Biocompatible Materials ; titanium alloy (TiAl6V4) (12743-70-3) ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2014-12
    Publishing country Scotland
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 91267-0
    ISSN 1878-4119 ; 1010-5182 ; 0301-0503
    ISSN (online) 1878-4119
    ISSN 1010-5182 ; 0301-0503
    DOI 10.1016/j.jcms.2014.07.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 882: Show issues Location:
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