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  1. Article ; Online: V. Aboyans et al. in response to the article by M. Helfre et al.: Usefulness of a systematic screening of carotid atherosclerosis in asymptomatic people with type 2 diabetes for cardiovascular risk reclassification. Ann Endocrinol (Paris). 2017;78:14-19.

    Aboyans, Victor / Desormais, Ileana / Jarlan, Lucile / Teissier, Marie-Pierre / Lacroix, Philippe

    Annales d'endocrinologie

    2017  Volume 78, Issue 5, Page(s) 484–485

    MeSH term(s) Aspirin/administration & dosage ; Cardiovascular Diseases/prevention & control ; Carotid Artery Diseases/diagnosis ; Diabetes Mellitus, Type 2/complications ; Humans ; Risk Factors
    Chemical Substances Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2017-09-01
    Publishing country France
    Document type Letter
    ZDB-ID 299-9
    ISSN 2213-3941 ; 0003-4266
    ISSN (online) 2213-3941
    ISSN 0003-4266
    DOI 10.1016/j.ando.2017.05.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Vascular ultrasound for cardiovascular risk stratification in asymptomatic patients with type-2 diabetes.

    Kenne Malaha, Angeladine / Magne, Julien / Jarlan, Lucile / Mansour, Katia / Ait-Ouatet, Melissa / Galinat, Sophie / Teissier, Marie-Pierre / Lacroix, Philippe / Desormais, Ileana / Aboyans, Victor

    Primary care diabetes

    2021  Volume 15, Issue 4, Page(s) 726–732

    Abstract: Aims: To identify new independent vascular markers to predict cardiovascular events in patients with type-2 diabetes (T2D), and their incremental value compared to the Swedish National Diabetes Register (NDR) risk score.: Methods: A retrospective ... ...

    Abstract Aims: To identify new independent vascular markers to predict cardiovascular events in patients with type-2 diabetes (T2D), and their incremental value compared to the Swedish National Diabetes Register (NDR) risk score.
    Methods: A retrospective cohort study was conducted on 1332 asymptomatic patients with T2D, free from prior CV event, assessed for a cardiovascular work-up, including Duplex ultrasonography to detect plaque on carotid and femoral arteries. The extent of atherosclerosis was rated as atherosclerosis burden score (ABS). Patients were followed up to 5 years and the occurrence of cardiovascular events recorded.
    Results: A total of 82 patients (6.2%) experienced a cardiovascular event, including 34 (2.6%) myocardial infarction, 18 (1.4%) cardiac revascularisation and 17 (1.3%) stroke. The independent determinants of these events were male sex (HR = 1.81 [1.13-2.88], p = 0.013) and ABS ≥ 2 (HR = 1.98 [1.21-3.25], p = 0.007). The NDR risk score performed poorly to predict cardiovascular events (area under the curve = 0.56 [0.49-0.63], p = 0.11), whereas screening for atherosclerotic plaques provided significant incremental prognostic value over the NDR score (model χ2 increase: +231%, p = 0.002).
    Conclusion: Duplex ultrasonography to screen for atherosclerotic plaques improve the estimation of cardiovascular prognosis on top of clinical data and could be routinely used to improve cardiovascular risk stratification.
    MeSH term(s) Cardiovascular Diseases/diagnostic imaging ; Cardiovascular Diseases/epidemiology ; Diabetes Mellitus, Type 2/diagnostic imaging ; Diabetes Mellitus, Type 2/epidemiology ; Heart Disease Risk Factors ; Humans ; Male ; Retrospective Studies ; Risk Assessment ; Risk Factors
    Language English
    Publishing date 2021-04-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2273997-X
    ISSN 1878-0210 ; 1751-9918
    ISSN (online) 1878-0210
    ISSN 1751-9918
    DOI 10.1016/j.pcd.2021.04.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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