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Article ; Online: Osteoarthritis year in review 2023: Imaging.

Jarraya, Mohamed / Guermazi, Ali / Roemer, Frank W

2023 Volume 32, Issue 1, Page(s) 18–27

Abstract: Purpose: This narrative review summarizes the original research in the field of in vivo osteoarthritis (OA) imaging between 1 January 2022 and 1 April 2023.: Methods: A PubMed search was conducted using the following several terms pertaining to OA ... ...

Abstract	Purpose: This narrative review summarizes the original research in the field of in vivo osteoarthritis (OA) imaging between 1 January 2022 and 1 April 2023. Methods: A PubMed search was conducted using the following several terms pertaining to OA imaging, including but not limited to "Osteoarthritis / OA", "Magnetic resonance imaging / MRI", "X-ray" "Computed tomography / CT", "artificial intelligence /AI", "deep learning", "machine learning". This review is organized by topics including the anatomical structure of interest and modality, AI, challenges of OA imaging in the context of clinical trials, and imaging biomarkers in clinical trials and interventional studies. Ex vivo and animal studies were excluded from this review. Results: Two hundred and forty-nine publications were relevant to in vivo human OA imaging. Among the articles included, the knee joint (61%) and MRI (42%) were the predominant anatomical area and imaging modalities studied. Marked heterogeneity of structural tissue damage in OA knees was reported, a finding of potential relevance to clinical trial inclusion. The use of AI continues to rise rapidly to be applied in various aspect of OA imaging research but a lack of generalizability beyond highly standardized datasets limit interpretation and wide-spread application. No pharmacologic clinical trials using imaging data as outcome measures have been published in the period of interest. Conclusions: Recent advances in OA imaging continue to heavily weigh on the use of AI. MRI remains the most important modality with a growing role in outcome prediction and classification.
MeSH term(s)	Humans ; Artificial Intelligence ; Osteoarthritis/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Tomography, X-Ray Computed ; Knee Joint ; Osteoarthritis, Knee/diagnostic imaging
Language	English
Publishing date	2023-10-23
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	1167809-4
ISSN	1522-9653 ; 1063-4584
ISSN (online)	1522-9653
ISSN	1063-4584
DOI	10.1016/j.joca.2023.10.005
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Article ; Online: Clinical imaging of marrow adiposity.

Jarraya, Mohamed / Bredella, Miriam A

Best practice & research. Clinical endocrinology & metabolism

2021 Volume 35, Issue 4, Page(s) 101511

Abstract: Research examining bone marrow adipose tissue (BMAT) has rapidly expanded during the last two decades, leading to advances in knowledge on the role of BMAT in the pathogenesis of bone loss and endocrine disorders. Clinical imaging has played a crucial ... ...

Abstract	Research examining bone marrow adipose tissue (BMAT) has rapidly expanded during the last two decades, leading to advances in knowledge on the role of BMAT in the pathogenesis of bone loss and endocrine disorders. Clinical imaging has played a crucial role for the in vivo assessment of BMAT, allowing non-invasive quantification and evaluation of BMAT composition. In the present work, we review different imaging methods for assessing properties of BMAT. Our aim is to review conventional magnetic resonance imaging (MRI), water-fat imaging, and single-voxel proton magnetic resonance spectroscopy (
MeSH term(s)	Adipose Tissue/diagnostic imaging ; Adiposity ; Bone Marrow/diagnostic imaging ; Diabetes Mellitus, Type 2/diagnostic imaging ; Humans ; Magnetic Resonance Imaging ; Obesity/diagnostic imaging
Language	English
Publishing date	2021-02-20
Publishing country	Netherlands
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	2052339-7
ISSN	1878-1594 ; 1532-1908 ; 1521-690X
ISSN (online)	1878-1594 ; 1532-1908
ISSN	1521-690X
DOI	10.1016/j.beem.2021.101511
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Article ; Online: A call for screening MRI as a tool for osteoarthritis clinical trials.

Guermazi, Ali / Roemer, Frank W / Jarraya, Mohamed / Hayashi, Daichi

Skeletal radiology

2023 Volume 52, Issue 11, Page(s) 2011–2019

Abstract: Conventional radiography is the most commonly used imaging modality for the evaluation of osteoarthritis (OA) in clinical trials of disease-modifying OA drugs (DMOADs). Unfortunately, radiography has many shortcomings as an imaging technique to ... ...

Abstract	Conventional radiography is the most commonly used imaging modality for the evaluation of osteoarthritis (OA) in clinical trials of disease-modifying OA drugs (DMOADs). Unfortunately, radiography has many shortcomings as an imaging technique to meaningfully assess the pathological features of OA. In this perspective paper, we will describe the reasons why radiography is not an ideal tool for structural OA assessment and why magnetic resonance imaging (MRI) should be preferred for such purposes. These shortcomings include a lack of reproducibility of radiographic joint space measurements (if conducted without using a standardized positioning frame), a lack of sensitivity and specificity, an insufficient definition of disease severity, a weak association of radiographic structural damage and pain, a lack of ability to depict many faces of OA, and incapability to depict diagnoses of exclusion. MRI offers solutions to these limitations of radiography. Several different phenotypes of OA have been recognized and it is important to recruit appropriate patients for specific therapeutic approaches in DMOAD trials. Radiography does not allow such phenotypical stratification. We will explain known hurdles for widespread deployment of MRI at eligibility screening and how they can be overcome by technological advances and the use of simplified image assessment.
MeSH term(s)	Humans ; Magnetic Resonance Imaging/methods ; Osteoarthritis/pathology ; Osteoarthritis, Knee/diagnostic imaging ; Radiography ; Reproducibility of Results ; Clinical Trials as Topic
Language	English
Publishing date	2023-05-01
Publishing country	Germany
Document type	Journal Article
ZDB-ID	527592-1
ISSN	1432-2161 ; 0364-2348
ISSN (online)	1432-2161
ISSN	0364-2348
DOI	10.1007/s00256-023-04354-z
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Article ; Online: The role of imaging in disentangling the enigma of osteoarthritis.

Guermazi, Ali / Hayashi, Daichi / Jarraya, Mohamed / Roemer, Frank W

Skeletal radiology

2023 Volume 52, Issue 11, Page(s) 2005–2006

MeSH term(s)	Humans ; Diagnostic Imaging ; Osteoarthritis/diagnostic imaging
Language	English
Publishing date	2023-09-05
Publishing country	Germany
Document type	Editorial
ZDB-ID	527592-1
ISSN	1432-2161 ; 0364-2348
ISSN (online)	1432-2161
ISSN	0364-2348
DOI	10.1007/s00256-023-04454-w
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Article: Effect of Yoga on Motor Skills and Self-Esteem in Kindergarten Children: A Randomized Controlled Trial.

Jarraya, Sana / Jarraya, Mohamed / Nouira, Saber

International journal of yoga therapy

2022 Volume 32, Issue 2022

Abstract: The present randomized controlled trial examines the effects of yoga, as opposed to general physical education (PE) and passive controls, on the motor skills and self-esteem of Tunisian kindergarten children. Fifty-four children (24 females, 30 males; ... ...

Abstract	The present randomized controlled trial examines the effects of yoga, as opposed to general physical education (PE) and passive controls, on the motor skills and self-esteem of Tunisian kindergarten children. Fifty-four children (24 females, 30 males; age 5.2 ± 0.6 years; weight 17.8 ± 2.3 kg; height 103.1 ± 5.0 cm; BMI 17.26 ± 0.46 kg/m2) were randomly divided into three groups of 18 (yoga, PE, and controls), and blindly administered the Eurofit physical fitness test battery and the Rosenberg Self-Esteem Scale prior to and after 12 weeks. During this period, the yoga and PE groups attended two weekly yoga and PE sessions of 30 minutes each, respectively. At T0, no significant differences between the groups were observed (p > 0.660). Repeated-measures analysis of variance associated yoga with higher levels of motor skills (p < 0.05; effect size for arm strength [ηp2] = 0.17, leg strength [ηp2] = 0.17, flexibility [ηp2] = 0.33; speed [ηp2] = 0.61, and balance [ηp2] = 0.19) and global self-esteem in comparison to the PE and control groups (p < 0.001; ηp2 = 0.42). Twelve weeks of kindergarten-based yoga appears to improve self-esteem and motor skills in 5-year-old children. The yoga intervention as a school routine seems to enhance development, health, and the well-being of children.
MeSH term(s)	Child, Preschool ; Female ; Humans ; Male ; Motor Skills ; Physical Fitness ; Schools ; Self Concept ; Yoga
Language	English
Publishing date	2022-08-01
Publishing country	United States
Document type	Journal Article ; Randomized Controlled Trial
ISSN	1531-2054
ISSN	1531-2054
DOI	10.17761/2022-D-21-00060
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Article ; Online: Kindergarten-Based Progressive Muscle Relaxation Training Enhances Attention and Executive Functioning: A Randomized Controlled Trial.

Jarraya, Sana / Jarraya, Mohamed / Engel, Florian A

Perceptual and motor skills

2022 Volume 129, Issue 3, Page(s) 644–669

Abstract: In the present study, we assessed the impact of kindergarten-based progressive muscle relaxation (PMR) on attention and executive functioning of 5-6-year-old children. In this randomized-controlled trial, 52 children (26 female; 26 male; ...

Abstract	In the present study, we assessed the impact of kindergarten-based progressive muscle relaxation (PMR) on attention and executive functioning of 5-6-year-old children. In this randomized-controlled trial, 52 children (26 female; 26 male;
MeSH term(s)	Attention ; Autogenic Training ; Child ; Child, Preschool ; Executive Function ; Exercise ; Female ; Humans ; Male ; Muscle Relaxation ; Schools
Language	English
Publishing date	2022-03-31
Publishing country	United States
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	204507-2
ISSN	1558-688X ; 0031-5125
ISSN (online)	1558-688X
ISSN	0031-5125
DOI	10.1177/00315125221080334
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Article ; Online: Effect of Social Context on Cognitive and Motor Behavior: A Systematic Review.

Mnif, Maha / Chikh, Soufien / Jarraya, Mohamed

Journal of motor behavior

2022 Volume 54, Issue 5, Page(s) 631–647

Abstract: Human cognitive and motor behavior is influenced by the social contexts. The aim of this systematic review is to investigate the impact of the social contexts on human behaviors. A systematic search of the literature was performed via Pub-Med/Medline, ... ...

Abstract	Human cognitive and motor behavior is influenced by the social contexts. The aim of this systematic review is to investigate the impact of the social contexts on human behaviors. A systematic search of the literature was performed via Pub-Med/Medline, Web of sciences, Google scholar, Science direct, Springer-Link and EMBASE and 68 articles were selected. After applying all the inclusion and exclusion criteria, 16 articles were retained. The results show that the presence of other people and the social context influence motor behavior (i.e. movement duration, trajectory behavior, maximum speed) and cognitive behavior (reaction time). Studies have shown an improvement in performance in the presence of other people compared to the individual situation. However, other studies showed that the presence of other people led to deterioration in performance compared to the individual situation. The improvement of behavior is attributed to the social phenomenon of facilitation while the deterioration was explained by the conduct theory or the distraction conflict theory. These social phenomena of facilitation or inhibition could be related to the perception-action theory, which interferes with interaction with other. This, in turn, seems to be associated with neural circuits of mirror neurons and motor system.
MeSH term(s)	Cognition ; Humans ; Mirror Neurons ; Movement ; Reaction Time ; Social Environment
Language	English
Publishing date	2022-04-05
Publishing country	United States
Document type	Journal Article ; Systematic Review
ZDB-ID	2066611-1
ISSN	1940-1027 ; 0022-2895
ISSN (online)	1940-1027
ISSN	0022-2895
DOI	10.1080/00222895.2022.2060928
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Article ; Online: One night of total sleep deprivation impairs decision-making skills, anaerobic performances, mood states, and perceptual responses in elite Kung-Fu athletes

Saddoud, Anis / Rekik, Ghazi / Belkhir, Yosra / Kammoun, Noureddine / Hidouri, Sami / Chlif, Mehdi / Jarraya, Mohamed

Biological Rhythm Research. 2023 Jan. 02, v. 54, no. 1 p.102-116

2023

Abstract: To explore how one night of total sleep deprivation (TSD) could affect cognitive and physical performances, as well as subjective experiences in 24 elite Kung-Fu athletes (age: 20.2 ± 1.76 years; body mass: 64.67 ± 6.52 kg; height: 1.71 ± 0.04 m). ... ...

Abstract	To explore how one night of total sleep deprivation (TSD) could affect cognitive and physical performances, as well as subjective experiences in 24 elite Kung-Fu athletes (age: 20.2 ± 1.76 years; body mass: 64.67 ± 6.52 kg; height: 1.71 ± 0.04 m). Participants completed, in a randomized counterbalanced order, two tests sessions in the late-afternoon (separated by 72-h recovery) under normal sleep (NS) and TSD conditions. Specific decision-making skills (decision accuracy (DA) and decision time (DT)), various anaerobic-exercises performance (i.e. seated medicine-ball throw (SMBT), horizontal jump (HJ), vertical jump (VJ), isometric back-muscles strength (IBMS), and isometric leg-muscles strength (ILMS)), mood states, and perceptual responses (attention and concentration) were assessed. The TSD was associated with lower values of vigor, and higher values of anxiety, depression, fatigue, anger, confusion, and total mood disturbance, compared to NS. The TSD resulted in lower attention and concentration, compared to NS. Similarly, lower performances of SMBT, HJ, VJ, and ILMS were recorded after TSD compared to NS. For cognitive performances, the TSD resulted in higher DA and lower DT, compared to NS. In summary, one night of TSD elicits negative effects on decision-making and anaerobic performance in Kung-Fu elites through disturbances in mood and attentional capacities.
Keywords	anxiety ; biological rhythms ; body weight ; cognition ; decision making ; research ; sleep deprivation ; vigor ; Total sleep deprivation ; sports performance ; mood ; attention ; Kung-Fu
Language	English
Dates of publication	2023-0102
Size	p. 102-116.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	1185065-6
ISSN	1744-4179 ; 0929-1016
ISSN (online)	1744-4179
ISSN	0929-1016
DOI	10.1080/09291016.2022.2090673
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Effects of Hatha yoga on cognitive functions in the elderly: a cross-sectional study.

Baklouti, Souad / Aloui, Asma / Baklouti, Hana / Souissi, Nizar / Jarraya, Mohamed

The Libyan journal of medicine

2022 Volume 17, Issue 1, Page(s) 2080799

Abstract: This study aimed to investigate the effects of Hatha yoga practice on cognitive functions in the elderly. Thirty healthy older men participated in this study. They belonged to 2 groups. The first group included 15 Hatha yoga practitioners for at least 2 ... ...

Abstract	This study aimed to investigate the effects of Hatha yoga practice on cognitive functions in the elderly. Thirty healthy older men participated in this study. They belonged to 2 groups. The first group included 15 Hatha yoga practitioners for at least 2 years. The control group involved 15 male older adults who shared the same characteristics (age, years of formal education, and level of physical activity) as the Hatha yoga group but were naive to yoga, meditation, or any mind-body intervention. Neuropsychological tests were applied to measure selective attention, sustained attention, episodic memory, and processing speed. The following tests were administered: The French adaptation of the Victoria Stroop test, the Zazzo's Cancellation Task, the Five Word Test, and a battery of computerized tests to evaluate reaction time. Long-term Hatha yoga practice showed promising results related to executive functions and reaction time, but no significant difference was found between the two groups in episodic memory and sustained attention although a trend of improvement was observed in favor of Hatha yoga practitioners. In conclusion, long-term Hatha yoga practitioners have better cognitive abilities compared to the control group in certain aspects of cognitive functions. Further physiological and psychological variables need to be examined in order to highlight the correlation between yoga intervention and cognitive performance.
MeSH term(s)	Aged ; Cognition ; Cross-Sectional Studies ; Exercise ; Humans ; Male ; Meditation ; Yoga/psychology
Language	English
Publishing date	2022-06-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2273005-9
ISSN	1819-6357 ; 1819-6357
ISSN (online)	1819-6357
ISSN	1819-6357
DOI	10.1080/19932820.2022.2080799
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Article ; Online: Crystal arthropathies and osteoarthritis-where is the link?

Jarraya, Mohamed / Roemer, Frank / Kwoh, C Kent / Guermazi, Ali

Skeletal radiology

2022 Volume 52, Issue 11, Page(s) 2037–2043

Abstract: Osteoarthritis (OA) is one of the leading causes of disability worldwide. As our understanding of OA progressively has moved from a purely mechanical "wear and tear" concept toward a complex multi-tissue condition in which inflammation plays a central ... ...

Abstract	Osteoarthritis (OA) is one of the leading causes of disability worldwide. As our understanding of OA progressively has moved from a purely mechanical "wear and tear" concept toward a complex multi-tissue condition in which inflammation plays a central role, the possible role of crystal-induced inflammation in OA incidence and progression may be relevant. In addition to gout, which affects 4% of the US population, basic calcium phosphate and calcium pyrophosphate deposition both may induce joint inflammation and may play a role in pain in OA. This narrative review article discusses the possible mechanisms underlying the associations between crystal-induced arthropathies and OA, and the important implications of these for clinical practice and future research.
MeSH term(s)	Humans ; Uric Acid ; Crystal Arthropathies/diagnostic imaging ; Gout ; Osteoarthritis/diagnostic imaging ; Inflammation ; Calcinosis/complications
Chemical Substances	Uric Acid (268B43MJ25)
Language	English
Publishing date	2022-12-20
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	527592-1
ISSN	1432-2161 ; 0364-2348
ISSN (online)	1432-2161
ISSN	0364-2348
DOI	10.1007/s00256-022-04246-8
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