Article ; Online: Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus.
Pediatric endocrinology, diabetes, and metabolism
2023 Volume 27, Issue 3, Page(s) 151–158
Abstract: Introduction: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in ... ...
| Title translation | Zastosowanie systemu ciągłego monitorowania glikemii u dzieci z dobrze kontrolowaną cukrzycą typu 1. |
|---|---|
| Abstract | Introduction: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study. Material and methods: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled metabolically (median HbA1c: 7.0%), and treated with continuous subcutaneous insulin infusion (CSII). The patients had used CGM for at least 150 days. We analysed the participants in subgroups based on baseline HbA1c < 7%, ≥ 7%, age, and sex. Results: Children with baseline HbA1c < 7% were characterized by significantly increased HbA1c after the median of 273 days (217; 320) of CGM usage (6.3% vs. 6.6%, respectively; p = 0.002). No significant change in HbA1c was noted in children with baseline HbA1c ≥ 7% (7.5% vs. 7.4%, respectively; p = 0.191), but 20% of the group reached the target of HbA1c < 7.0%. The analysis of CGM data revealed that no group achieved the CGM targets of good metabolic control. Total daily insulin requirements remained stable in both groups (p = 0.752; p = 0.274), but the amount of basal insulin increased statistically in both groups (p = 0.009; p ≤ 0.001). Conclusions: The application of CGM provides detailed information concerning glycaemic control and is beneficial in some, but not all, T1D children with good diabetes control. |
| MeSH term(s) | Blood Glucose ; Blood Glucose Self-Monitoring ; Child ; Diabetes Mellitus, Type 1/drug therapy ; Female ; Glycated Hemoglobin/analysis ; Humans ; Hypoglycemic Agents/therapeutic use ; Insulin/therapeutic use ; Insulin Infusion Systems |
| Chemical Substances | Blood Glucose ; Glycated Hemoglobin A ; Hypoglycemic Agents ; Insulin |
| Language | English |
| Publishing date | 2023-02-10 |
| Publishing country | Poland |
| Document type | Journal Article |
| ZDB-ID | 2617120-X |
| ISSN | 2083-8441 ; 2083-8441 |
| ISSN (online) | 2083-8441 |
| ISSN | 2083-8441 |
| DOI | 10.5114/pedm.2021.107717 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.