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  1. Article: Growth and decomposition of millets in Odisha: 1960–61 to 2019–20

    Jena, D. / Mishra, S.

    Agricultural science digest. 2022 June, v. 42, no. 3

    2022  

    Abstract: Odisha started a programme to revive millets in 2017. Keeping this in the background, this paper examines growth of production, area and yield and decomposition of production of millets in Odisha in the last six decades by using triennium ending data, ... ...

    Abstract Odisha started a programme to revive millets in 2017. Keeping this in the background, this paper examines growth of production, area and yield and decomposition of production of millets in Odisha in the last six decades by using triennium ending data, TE1962–63 to TE2019–20. Boyce's kinked exponential method has been used to estimate growth for production, area and yield. Production was decomposed to area, yield and interaction effects. Millets as a crop group is compared with other foodgrain groups and then analysis was carried out for four specific millet crops- ragi, jowar, bajra and small millets. In Odisha, the 1960s and 1970s indicate an increasing trend in production of and area under millets. There is a reversal of these trends since 1980s. The decline started first for small millets in the 1980s and subsequently since the 1990s for the three major millets- bajra, jowar and ragi. Decomposition of millets production indicates that the decline since 1980s is largely on account of area effect, but also because of yield effect in the 1990s and 2010s.
    Keywords Cenchrus americanus ; Eleusine coracana subsp. coracana ; agricultural sciences ; millets
    Language English
    Dates of publication 2022-06
    Size p. 272-277.
    Publishing place Agricultural Research Communication Centre
    Document type Article
    ISSN 0976-0547
    DOI 10.18805/ag.D-5447
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Challenges and Therapeutic Approaches for the Protein Delivery System: A Review.

    Jena, Devashish / Nimisha / Chauhan, Iti / Verma, Madhu

    Pharmaceutical nanotechnology

    2024  

    Abstract: The protein delivery system is one of the innovative or novel drug delivery systems in the present era. Proteins play an indispensable role in our body and are mainly found in every part, like tissue and cells of our body. It also controls various ... ...

    Abstract The protein delivery system is one of the innovative or novel drug delivery systems in the present era. Proteins play an indispensable role in our body and are mainly found in every part, like tissue and cells of our body. It also controls various functions, such as maintaining our tissue, transportation, muscle recovery, enzyme production and acting as an energy source for our body. Protein therapeutics have big future perspectives, and their use in the treatment of a wide range of serious diseases has transformed the delivery system in the pharmaceutical and biotechnology industries. The chief advantage of protein delivery is that it can be delivered directly to the systemic circulation. So far, parenteral routes, such as intravenous, intramuscular, and subcutaneous, are the most often used method of administering protein drugs. Alternative routes like buccal, oral, pulmonary, transdermal, nasal, and ocular routes have also shown a remarkable success rate. However, as with all other types of delivery, here, several challenges are posed due to the presence of various barriers, such as the enzymatic barrier, intestinal epithelial barrier, capillary endothelial barrier, and blood-brain barrier. There are several approaches that have been explored to overcome these barriers, such as chemical modification, enzymatic inhibitors, penetration enhancers, and mucoadhesive polymers. This review article discusses the protein, its functions, routes of administration, challenges, and strategies to achieve ultimate formulation goals. Recent advancements like the protein Pegylation method and Depofoam technology are another highlight of the article.
    Language English
    Publishing date 2024-01-08
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 2211-7393
    ISSN (online) 2211-7393
    DOI 10.2174/0122117385265979231115074255
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Immunotherapy for advanced thyroid cancers - rationale, current advances and future strategies.

    French, Jena D

    Nature reviews. Endocrinology

    2020  Volume 16, Issue 11, Page(s) 629–641

    Abstract: In the past decade, the field of cancer immunotherapy has been revolutionized by immune checkpoint blockade (ICB) technologies. Success across a broad spectrum of cancers has led to a paradigm shift in therapy for patients with advanced cancer. Early ... ...

    Abstract In the past decade, the field of cancer immunotherapy has been revolutionized by immune checkpoint blockade (ICB) technologies. Success across a broad spectrum of cancers has led to a paradigm shift in therapy for patients with advanced cancer. Early data are now accumulating in progressive thyroid cancers treated with single-agent ICB therapies and combination approaches that incorporate ICB technologies. This Review discusses our current knowledge of the immune response in thyroid cancers, the latest and ongoing immune-based approaches, and the future of immunotherapies in thyroid cancer. Physiologically relevant preclinical mouse models and human correlative research studies will inform development of the next stage of immune-based therapies for patients with advanced thyroid cancer.
    MeSH term(s) Animals ; Combined Modality Therapy ; Humans ; Immune Checkpoint Inhibitors ; Immunotherapy/methods ; Immunotherapy/trends ; Mice ; Thyroid Neoplasms/genetics ; Thyroid Neoplasms/immunology ; Thyroid Neoplasms/therapy
    Chemical Substances Immune Checkpoint Inhibitors
    Keywords covid19
    Language English
    Publishing date 2020-08-24
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2489381-X
    ISSN 1759-5037 ; 1759-5029
    ISSN (online) 1759-5037
    ISSN 1759-5029
    DOI 10.1038/s41574-020-0398-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Amino-functionalized novel biosorbent for effective removal of fluoride from water: process optimization using artificial neural network and mechanistic insights.

    Jena, Dipankar / Bej, Anjan Kumar / Giri, Anil Kumar / Mishra, Prakash Chandra

    Environmental science and pollution research international

    2024  Volume 31, Issue 20, Page(s) 29415–29433

    Abstract: Aqueous fluoride ( ...

    Abstract Aqueous fluoride (
    MeSH term(s) Fluorides/chemistry ; Neural Networks, Computer ; Adsorption ; Water Pollutants, Chemical/chemistry ; Water Purification/methods ; Kinetics ; Water/chemistry
    Chemical Substances Fluorides (Q80VPU408O) ; Water Pollutants, Chemical ; Water (059QF0KO0R)
    Language English
    Publishing date 2024-04-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-33046-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Immunotherapy for advanced thyroid cancers - rationale, current advances and future strategies

    French, Jena D

    Nat. rev. endocrinol

    Abstract: In the past decade, the field of cancer immunotherapy has been revolutionized by immune checkpoint blockade (ICB) technologies. Success across a broad spectrum of cancers has led to a paradigm shift in therapy for patients with advanced cancer. Early ... ...

    Abstract In the past decade, the field of cancer immunotherapy has been revolutionized by immune checkpoint blockade (ICB) technologies. Success across a broad spectrum of cancers has led to a paradigm shift in therapy for patients with advanced cancer. Early data are now accumulating in progressive thyroid cancers treated with single-agent ICB therapies and combination approaches that incorporate ICB technologies. This Review discusses our current knowledge of the immune response in thyroid cancers, the latest and ongoing immune-based approaches, and the future of immunotherapies in thyroid cancer. Physiologically relevant preclinical mouse models and human correlative research studies will inform development of the next stage of immune-based therapies for patients with advanced thyroid cancer.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32839578
    Database COVID19

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  6. Article ; Online: Insertion loss of regular finite cylinder arrays with porous layers between the rows.

    Jena, D P / Qiu, Xiaojun

    The Journal of the Acoustical Society of America

    2021  Volume 149, Issue 4, Page(s) 2395

    Abstract: It has been demonstrated recently via simulations in a duct that the sound transmission loss of porous materials can be increased with embedded periodic scatterers [Jena and Qiu, J. Acoust. Soc. Am. 147, 978-983 (2020)]. In this paper, the insertion loss ...

    Abstract It has been demonstrated recently via simulations in a duct that the sound transmission loss of porous materials can be increased with embedded periodic scatterers [Jena and Qiu, J. Acoust. Soc. Am. 147, 978-983 (2020)]. In this paper, the insertion loss (IL) of two types of finite size structures constructed by installing two parallel porous sheets within rows of periodic scatterers is investigated in free field. One structure uses rigid cylindrical shells, while the other uses split ring shells, which are obtained by making uniform vertical slits in cylindrical shells. The simulation results show that the mixed structure has larger IL than the summation of the ILs of the individual periodic scatterers and two parallel porous sheets in the frequency range after the first bandgap due to Bragg diffraction, and an additional peak in IL is introduced for the split ring scatterers due to their local resonance. The amplitude, frequency, and bandwidth of the resonance peak can be tuned by changing the geometry of the slit for some specific broadband sound absorption. Finally, the experiment results obtained in an anechoic chamber are presented to support the simulation results and analyses.
    Language English
    Publishing date 2021-05-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219231-7
    ISSN 1520-8524 ; 0001-4966
    ISSN (online) 1520-8524
    ISSN 0001-4966
    DOI 10.1121/10.0004131
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Experimental and

    Panda, Itishree / Behera, Bikash Ranjan / Jena, Debasmita / Behera, Santosh Kumar / Samal, Sangram Keshari / Pradhan, Sanghamitra

    RSC advances

    2024  Volume 14, Issue 4, Page(s) 2453–2465

    Abstract: Ionic liquids have gained attention as 'designer solvents' since they offer a broad spectrum of properties that can be tuned by altering the constituent ions. In this work, 1-alkyl-2-methyl imidazolium-based ionic liquids with two different alkyl chains ( ...

    Abstract Ionic liquids have gained attention as 'designer solvents' since they offer a broad spectrum of properties that can be tuned by altering the constituent ions. In this work, 1-alkyl-2-methyl imidazolium-based ionic liquids with two different alkyl chains (alkyl = hexyl and octyl) have been synthesized and characterized. Since the binary mixture of ionic liquids with molecular solvents can give rise to striking physicochemical properties, the interaction of the synthesized room temperature ionic liquids, 1-hexyl-2-methyl imidazolium bromide [HMIM][Br]/1-octyl-2-methyl imidazolium bromide [OMIM][Br] with DMSO has been examined through density and specific conductance at
    Language English
    Publishing date 2024-01-12
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra07417j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Trends in gynecological cancer incidence, mortality, and survival among elderly women: A SEER study.

    Priyadarshini, Subhadra / Swain, Prafulla Kumar / Agarwal, Khushi / Jena, Diptismita / Padhee, Sourav

    Aging medicine (Milton (N.S.W))

    2024  Volume 7, Issue 2, Page(s) 179–188

    Abstract: Objectives: This paper aims to comprehensively analyze trends in gynecological cancers among elderly women in the United States from 1975 to 2020.: Methods: Surveillance, Epidemiology, and End Results (SEER) population data were utilized for the ... ...

    Abstract Objectives: This paper aims to comprehensively analyze trends in gynecological cancers among elderly women in the United States from 1975 to 2020.
    Methods: Surveillance, Epidemiology, and End Results (SEER) population data were utilized for the analysis. Annual Percentage Change (APC) and Average APC were estimated using join-point regression to assess trends in mortality rates.
    Results: The study reveals an increasing pattern of incidence and mortality in all gynaecological cancer sites except cervical cancer among elderly. The incidence of cervical cancer decreased from 1975 to 2007 and then increased, whereas cancer-specific mortality decreased from 1977 to 2020, indicating positive advancements in detection and treatment.
    Conclusions: Despite progress in managing certain gynecological cancers, challenges persist, particularly evidenced by increasing mortality rates for cancers in other female genital organs. This underscores the necessity for sustained research efforts and targeted interventions to address these ongoing challenges effectively.
    Language English
    Publishing date 2024-04-29
    Publishing country Australia
    Document type Journal Article
    ISSN 2475-0360
    ISSN (online) 2475-0360
    DOI 10.1002/agm2.12297
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Six-Year Follow-up of Childhood Stimulation on Development of Children With and Without Anemia.

    Hossain, Sheikh Jamal / Tofail, Fahmida / Mehrin, Syeda Fardina / Hamadani, Jena D

    Pediatrics

    2023  Volume 151, Issue Suppl 2

    Abstract: Background and objectives: Previously, in 30 Bangladeshi villages, 2 groups of children with iron-deficiency anemia (IDA) and nonanemic (NA) iron sufficiency aged 6 to 24 months participated in 2 parallel cluster randomized controlled trials of the ... ...

    Abstract Background and objectives: Previously, in 30 Bangladeshi villages, 2 groups of children with iron-deficiency anemia (IDA) and nonanemic (NA) iron sufficiency aged 6 to 24 months participated in 2 parallel cluster randomized controlled trials of the effect of psychosocial stimulation on neurodevelopment. The intervention was composed of weekly play sessions at home for 9 months. All children with anemia received iron treatment of 6 months. The intervention improved the mental development of NA but not IDA groups. Six years after end line when the children were aged 8 to 9 years, we aimed to determine if benefits were sustained in the NA group or late-onset benefits emerged in the IDA group.
    Methods: We relocated 372 (90%) of the initial 412 children from all the clusters (villages), and assessed their IQ with the Wechsler Abbreviated Scale of Intelligence-II, motor development, and school achievement including math, spelling, and reading. Analyses were by intention-to-treat, adjusting for clustering.
    Results: There was a significant interaction between anemia groups (IDA/NA) and intervention on IQ. The intervention benefitted the NA group's Full-Scale IQ (effect size, 0.43 [95% confidence interval, 0.08-0.79]) and Perceptual Reasoning Index (effect size, 0.48 [95% confidence interval, 0.08-0.89]) but did not affect the IDA group's outcomes. No other outcomes were significant.
    Conclusions: The benefits from early childhood psychosocial stimulation on the NA group's IQ, 6 years after intervention ended, adds to the limited evidence on the sustainability of benefits in low- and middle-income countries. Reasons for lack of effect in children with anemia are unknown.
    MeSH term(s) Humans ; Child ; Child, Preschool ; Infant ; Follow-Up Studies ; Anemia ; Iron ; Anemia, Iron-Deficiency/therapy ; Child Development
    Chemical Substances Iron (E1UOL152H7)
    Language English
    Publishing date 2023-04-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.2023-060221E
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Statistical modeling and estimating number of healthy life years lost and healthy life expectancy in India, 2000-2019.

    Jena, Diptismita / Swain, Prafulla Kumar / Tripathy, Manas Ranjan / Sarangi, Pravat Kumar

    Aging medicine (Milton (N.S.W))

    2023  Volume 6, Issue 4, Page(s) 435–445

    Abstract: Objective: In this study, our objective is to propose various models to estimate healthy life year lost (HLYL) and healthy life expectancy (HLE) in India.: Methods: The HLYL and HLE were estimated and further these estimates were compared with the ... ...

    Abstract Objective: In this study, our objective is to propose various models to estimate healthy life year lost (HLYL) and healthy life expectancy (HLE) in India.
    Methods: The HLYL and HLE were estimated and further these estimates were compared with the direct life table method and the World Health Organization (WHO) method. From the mortality perspective, we have developed a log-logistic model for estimating the parameter (bx), which is characterized by HLYL. The results were compared with other models, such as the Gompertz and Weibull model. Here, we have also obtained the HLE by subtracting HLYL from the total life expectancy.
    Results: The result shows an increasing trend of HLYL among the male, female, and the total population in India.
    Conclusion: From the log-logistic model, the HLYL was estimated as 8.79 years, 8.36 years, and 9.38 years for the total, male, and female populations, respectively, in India during 2019.
    Language English
    Publishing date 2023-09-27
    Publishing country Australia
    Document type Journal Article
    ISSN 2475-0360
    ISSN (online) 2475-0360
    DOI 10.1002/agm2.12269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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