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  1. Article: Integrating Molecular Diagnostics and GIS Mapping: A Multidisciplinary Approach to Understanding Tuberculosis Disease Dynamics in South Africa Using Xpert MTB/RIF.

    Scott, Lesley Erica / Shapiro, Anne Nicole / Da Silva, Manuel Pedro / Tsoka, Jonathan / Jacobson, Karen Rita / Emch, Michael / Moultrie, Harry / Jenkins, Helen Elizabeth / Moore, David / Van Rie, Annelies / Stevens, Wendy Susan

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 20

    Abstract: An investigation was carried out to examine the use of national Xpert MTB/RIF data (2013-2017) and GIS technology for MTB/RIF surveillance in South Africa. The aim was to exhibit the potential of using molecular diagnostics for TB surveillance across the ...

    Abstract An investigation was carried out to examine the use of national Xpert MTB/RIF data (2013-2017) and GIS technology for MTB/RIF surveillance in South Africa. The aim was to exhibit the potential of using molecular diagnostics for TB surveillance across the country. The variables analysed include
    Language English
    Publishing date 2023-10-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13203163
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Pediatric Multidrug-resistant Tuberculosis in Kyiv City, Ukraine.

    Chiang, Silvia Shinpei / Sheremeta, Yana / Padilla, Rachel Sophie / Jenkins, Helen Elizabeth / Horsburgh, Charles Robert / Petrenko, Vasyl / Rybak, Natasha Renee

    Journal of epidemiology and global health

    2019  Volume 9, Issue 1, Page(s) 56–61

    Abstract: Few reports have described pediatric Multidrug-resistant Tuberculosis (MDR-TB) in the former Soviet republics, despite the fact that these countries have the highest proportion of TB cases that are MDR. We aimed to examine pediatric MDR-TB in Ukraine. ... ...

    Abstract Few reports have described pediatric Multidrug-resistant Tuberculosis (MDR-TB) in the former Soviet republics, despite the fact that these countries have the highest proportion of TB cases that are MDR. We aimed to examine pediatric MDR-TB in Ukraine. This retrospective cohort study included all children <18 years of age who started undergoing MDR-TB treatment between January 1, 2011 and July 31, 2016 at Kyiv City Pediatric TB Hospital. From each child's clinical chart, we abstracted demographic and clinical data. Using Fisher's exact test, we compared characteristics between children with microbiologically confirmed vs. probable (i.e., clinically diagnosed) MDR-TB. The study population included 20 children with a median age of 5 years. At diagnosis, 12 (60%) had intrathoracic lymphadenopathy as their only radiographic abnormality, and two (10%) were asymptomatic. Children with confirmed MDR-TB were more likely to be adolescents or have radiologic abnormalities in addition to intrathoracic lymphadenopathy. Median treatment duration was 20 months. Eighteen (90%) children were treated successfully. The remaining two were transferred to another facility, and their final outcomes were unknown. The excellent outcomes in this cohort are consistent with high treatment success rates for pediatric MDR-TB reported in other parts of the world.
    MeSH term(s) Adolescent ; Antitubercular Agents/therapeutic use ; Child ; Child, Preschool ; Female ; Humans ; Male ; Mycobacterium tuberculosis/drug effects ; Retrospective Studies ; Tuberculosis, Multidrug-Resistant/epidemiology ; Ukraine/epidemiology
    Chemical Substances Antitubercular Agents
    Language English
    Publishing date 2019-02-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2645324-1
    ISSN 2210-6014 ; 2210-6014
    ISSN (online) 2210-6014
    ISSN 2210-6014
    DOI 10.2991/jegh.k.190225.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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