Article ; Online: The alarmin IL33 orchestrates type 2 immune-mediated control of thymus regeneration.
2023 Volume 14, Issue 1, Page(s) 7201
Abstract: As the primary site of T-cell development, the thymus dictates immune competency of the host. The rates of thymus function are not constant, and thymus regeneration is essential to restore new T-cell production following tissue damage from environmental ... ...
Abstract | As the primary site of T-cell development, the thymus dictates immune competency of the host. The rates of thymus function are not constant, and thymus regeneration is essential to restore new T-cell production following tissue damage from environmental factors and therapeutic interventions. Here, we show the alarmin interleukin (IL) 33 is a product of Sca1 |
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MeSH term(s) | Interleukin-33 ; Alarmins ; Immunity, Innate ; Interleukin-4 ; Lymphocytes |
Chemical Substances | Interleukin-33 ; Alarmins ; Interleukin-4 (207137-56-2) |
Language | English |
Publishing date | 2023-11-08 |
Publishing country | England |
Document type | Journal Article ; Research Support, Non-U.S. Gov't |
ZDB-ID | 2553671-0 |
ISSN | 2041-1723 ; 2041-1723 |
ISSN (online) | 2041-1723 |
ISSN | 2041-1723 |
DOI | 10.1038/s41467-023-43072-x |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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