LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Your last searches

  1. AU="Jennifer Huang"
  2. AU="Kim, Eun-Jin"

Search results

Result 1 - 10 of total 18

Search options

  1. Article ; Online: OpenNotes: transparency versus stigma in patient care.

    Harris, Jennifer Huang / Levy-Carrick, Nomi C / Nadkarni, Ashwini

    The lancet. Psychiatry

    2022  Volume 9, Issue 6, Page(s) 426–428

    MeSH term(s) Electronic Health Records ; Humans ; Patient Care ; Physician-Patient Relations ; Social Stigma
    Language English
    Publishing date 2022-03-24
    Publishing country England
    Document type Journal Article
    ISSN 2215-0374
    ISSN (online) 2215-0374
    DOI 10.1016/S2215-0366(22)00062-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Dynamics of the HIV epidemic in MSM.

    Jia, Yujiang / Aliyu, Muktar H / Jennifer Huang, Z

    BioMed research international

    2014  Volume 2014, Page(s) 497543

    MeSH term(s) Epidemics ; HIV/pathogenicity ; HIV Infections/epidemiology ; Homosexuality, Male ; Humans ; Male
    Language English
    Publishing date 2014-06-29
    Publishing country United States
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2014/497543
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Sirt3 Pharmacologically Promotes Insulin Sensitivity through PI3/AKT/mTOR and Their Downstream Pathway in Adipocytes

    Alexandra Yatine Lee / Sabrina Marie Christensen / Nhi Duong / Quoc-Anh Tran / Hou Mai Xiong / Jennifer Huang / Sarah James / Dimple Vallabh / George Talbott / Melanie Rose / Linh Ho

    International Journal of Molecular Sciences, Vol 23, Iss 3740, p

    2022  Volume 3740

    Abstract: Sirtuin-3 (Sirt3) is a major mitochondrial deacetylase enzyme that regulates multiple metabolic pathways, and its expression is decreased in diabetes type 1 and type 2 diabetes. This study aimed to elucidate Sirt3′s molecular mechanism in regulating ... ...

    Abstract Sirtuin-3 (Sirt3) is a major mitochondrial deacetylase enzyme that regulates multiple metabolic pathways, and its expression is decreased in diabetes type 1 and type 2 diabetes. This study aimed to elucidate Sirt3′s molecular mechanism in regulating insulin sensitivity in adipocytes that can contribute to the effort of targeting Sirt3 for the treatment of obesity and type 2 diabetes. We found that the Sirt3 activator honokiol (HNK) induced adipogenesis compared to the control, in contrast to Sirt3 inhibitor, 3-TYP. Accordingly, HNK increased expression of adipocyte gene markers, gene-involved lipolysis and glucose transport (GLUT4), while 3-TYP reduced expression of those genes. Interestingly, 3-TYP caused an increase in gene expression of adipocyte-specific cytokines including IL6, resistin, and TNF-α. However, changes in adipocyte-specific cytokines in HNK treated cells were not significant. In addition, HNK stimulated insulin pathway by promoting insulin receptor beta (IRβ) and PI3K/AKT/mTOR pathways, resulting in an increase in phosphorylation of the forkhead family FoxO1/FoxO3a/FoxO4 and glycogen synthase kinase-3 (GSK-3β), opposing 3-TYP. In line with these findings, HNK increased free fatty acid and glucose uptake, contrary to 3-TYP. In conclusion, Sirt3 activator-HNK induced adipogenesis and lipolysis reduced adipocytes specific cytokines. Intriguingly, HNK activated insulin signaling pathway and increased free fatty acid as well as glucose uptake and transport, in sharp contrast to 3-TYP. These results indicate that, via insulin signaling regulation, Sirt3 activation by HNK improves insulin resistance, while Sirt3 inhibition by 3-TYP might precipitate insulin resistance.
    Keywords Sirt3 ; Sirt3 activator ; Sirt3 inhibitor ; honokiol ; 3-TYP ; adipocytes ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Subject code 571 ; 616
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  4. Article ; Online: Dynamics of the HIV Epidemic in MSM

    Yujiang Jia / Muktar H. Aliyu / Z. Jennifer Huang

    BioMed Research International, Vol

    2014  Volume 2014

    Keywords Medicine ; R
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  5. Article ; Online: Impact of acculturation and psychological adjustment on mental health among migrant adolescents in Guangzhou, China: a cross-sectional questionnaire study.

    Shi, Lishuo / Chen, Wen / Bouey, Jennifer Huang / Lin, Yanwei / Ling, Li

    BMJ open

    2019  Volume 9, Issue 5, Page(s) e022712

    Abstract: Objectives: The aim of this study was to examine the pathway and associations among acculturation (ie, language, social interaction and lifestyle), psychological adjustment and mental health of internal migrant adolescents in China.: Design: Cross- ... ...

    Abstract Objectives: The aim of this study was to examine the pathway and associations among acculturation (ie, language, social interaction and lifestyle), psychological adjustment and mental health of internal migrant adolescents in China.
    Design: Cross-sectional questionnaire study.
    Setting: Six private migrant junior high schools located in Tianhe and Baiyun districts in Guangzhou were chosen as the study sites.
    Participants: A total of 1122 migrant adolescents aged 11-17 years old completed the study.
    Main outcome measures: Mental health was measured by using the Social Anxiety Scale for Children (SASC) and major depression disorder (MDD) in a Brief Child and Family Phone Interview. Acculturation and psychological adjustment were measured by a self-designed and verified questionnaire. Multiple regression models and structural equation models were performed to analyse the association among acculturation, psychological adjustment and mental health while controlling for participant demographic characteristics.
    Results: The average MDD score for boys was 8.78 (SD=2.17) and for girls was 8.56 (SD=2.22), while the average SASC score for boys was 14.67 (SD=3.72) and for girls was 13.41 (SD=4.01). Psychological adjustment had a direct positive effect on MDD (p<0.001, β=0.30) and SASC (p<0.001, β=0.28), and it was the key variable fully mediating the impact of acculturation components on MDD and partly mediating the impact of acculturation on SASC, whereas lifestyle showed a direct negative effect (p=0.003, β=-0.17) on SASC. Of the three acculturation components, lifestyle had the strongest influence on psychological adjustment (p<0.001, β=0.37 and 0.51), followed by social interaction (p<0.001, β=0.24 and 0.13) and language (p<0.001, β=0.17 and 0.11).
    Conclusions: The association between acculturation and the mental health of internal migrant adolescents was complex and could be mediated by psychological adjustment. Interventions such as promoting local language and social interaction are needed to enhance psychological adjustment and further improve the mental health of migrant adolescents.
    MeSH term(s) Acculturation ; Adaptation, Psychological ; Adolescent ; Adolescent Health ; Child ; China/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Interpersonal Relations ; Male ; Mental Health ; Social Adjustment ; Surveys and Questionnaires ; Transients and Migrants/psychology
    Language English
    Publishing date 2019-05-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2747269-3
    ISSN 2044-6055 ; 2044-6055 ; 2053-3624
    ISSN (online) 2044-6055
    ISSN 2044-6055 ; 2053-3624
    DOI 10.1136/bmjopen-2018-022712
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Improved Water and Waste Management Practices Reduce Diarrhea Risk in Children under Age Five in Rural Tanzania

    Paul H. McClelland / Claire T. Kenney / Federico Palacardo / Nicholas L. S. Roberts / Nicholas Luhende / Jason Chua / Jennifer Huang / Priyanka Patel / Leonardo Albertini Sanchez / Won J. Kim / John Kwon / Paul J. Christos / Madelon L. Finkel

    International Journal of Environmental Research and Public Health, Vol 19, Iss 4218, p

    A Community-Based, Cross-Sectional Analysis

    2022  Volume 4218

    Abstract: Diarrhea remains a significant cause of morbidity and mortality among children in developing countries. Water, sanitation, and hygiene practices (WASH) have demonstrated improved diarrhea-related outcomes but may have limited implementation in certain ... ...

    Abstract Diarrhea remains a significant cause of morbidity and mortality among children in developing countries. Water, sanitation, and hygiene practices (WASH) have demonstrated improved diarrhea-related outcomes but may have limited implementation in certain communities. This study analyzes the adoption and effect of WASH-based practices on diarrhea in children under age five in the rural Busiya chiefdom in northwestern Tanzania. In a cross-sectional analysis spanning July-September 2019, 779 households representing 1338 under-five children were surveyed. Among households, 250 (32.1%) reported at least one child with diarrhea over a two-week interval. Diarrhea prevalence in under-five children was 25.6%. In per-household and per-child analyses, the strongest protective factors against childhood diarrhea included dedicated drinking water storage (OR 0.25, 95% CI 0.18–0.36; p < 0.001), improved waste management (OR 0.37, 95% CI 0.27–0.51; p < 0.001), and separation of drinking water (OR 0.38, 95% CI 0.24–0.59; p < 0.001). Improved water sources were associated with decreased risk of childhood diarrhea in per-household analysis (OR 0.72, 95% CI 0.52–0.99, p = 0.04), but not per-child analysis (OR 0.83, 95% CI 0.65–1.05, p = 0.13). Diarrhea was widely treated (87.5%), mostly with antibiotics (44.0%) and oral rehydration solution (27.3%). Targeting water transportation, storage, and sanitation is key to reducing diarrhea in rural populations with limited water access.
    Keywords WASH ; drinking water ; diarrhea ; children under five ; prevention ; hygiene ; Medicine ; R
    Subject code 360
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  7. Article ; Online: Teaching Cultural Competency through Global Health Education at Weill Cornell Medicine

    Katharine-Grace Norris / Caitlin Noonan / Roger Ying / Claire T. Kenney / Jennifer Huang / Brienne Lubor / Rohini Kopparam / Elena Beideck / Priyanka Patel / Madelon L. Finkel

    International Journal of Medical Students, Vol 8, Iss 1, Pp 15-

    2020  Volume 19

    Abstract: Background: Educating medical students to better understand the complexities of cultural competence, the social determinants and environmental determinants of health that are important and integral components of the medical school curriculum. Methods: In ...

    Abstract Background: Educating medical students to better understand the complexities of cultural competence, the social determinants and environmental determinants of health that are important and integral components of the medical school curriculum. Methods: In 2014, Weill Cornell Medicine (WCM) implemented a new curriculum, the adoption of which provided the means to enhance an existing global health program, informally introduced in 2009, and to address the issues of cultural competency. In this article, we share WCM’s experience in building and expanding its global health curriculum. Results: A hallmark of our program is the successful collaboration between students and faculty to create a multi-disciplinary global health program that incorporates electives, clinical field placement, and collaborative research. Conclusion: Key lessons learned through our experience include the necessity for strong faculty-student collaboration, full support from the administration, and building global partnerships. Our example could be a useful guide for other medical schools seeking to establish a global health education curriculum.
    Keywords global health education ; cultural competency ; Medicine (General) ; R5-920 ; Public aspects of medicine ; RA1-1270
    Subject code 027
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher International Journal of Medical Students
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  8. Article ; Online: Intimate-Partner and Client-Initiated Violence among Female Street-Based Sex Workers in China

    Katie Hail-Jares / Ruth C F Chang / Sugy Choi / Huang Zheng / Na He / Z Jennifer Huang

    PLoS ONE, Vol 10, Iss 9, p e

    Does a Support Network Help?

    2015  Volume 0139161

    Abstract: Globally, female street-based sex workers are vulnerable to gender-based violence. Previous research has shown having a peer social network can reduce sex workers' risks of victimization. However, mechanisms of how social network impacts violence among ... ...

    Abstract Globally, female street-based sex workers are vulnerable to gender-based violence. Previous research has shown having a peer social network can reduce sex workers' risks of victimization. However, mechanisms of how social network impacts violence among female street-based sex workers are still far from clear.Our study was based on data abstracted from a paper-and-pencil survey administered among 218 female street-based sex workers in Shanghai, China. We focused on self-reported client-initiated violence and intimate-partner violence in emotional, physical, and sexual forms. Social networks were characterized by the size and sources of financial and psychosocial support (e.g. family, friends, and peers). Multi-variable logistic regression was used to estimate adjusted odds ratios (AOR) of each type of violence exposure by social network structure after the adjustment of age, education, and years in Shanghai.The street-based female sex workers in our study were primarily rural-to-urban migrants (95.7%) with an average age of 41 years old. 24.3% and 62.8% of the sex workers reported intimate-partner violence and client-initiated violence respectively. Lack of financial support, as defined by having only one individual or none in her peer support system to help financially, was significantly associated with self-reported intimate-partner violence (AOR: 2.5; 95% CI: 1.1-5.9). Respondents who reported client-initiated violence, by contrast, were more likely to report lacked psychosocial support from family (AOR: 2.2, 95% CI: 1.0-4.6) and peers (AOR: 5.1, 95% CI: 2.2-11).This study is one of the first to systematically analyze the associations between social network and gender-based violence among street-based female sex worker. We reported a high prevalence of both types of gender-based violence and their complex associations with family, friends, and peer support network. Policies with goals to reduce violence against women may apply these findings to leverage social network in the interventions against gender-based ...
    Keywords Medicine ; R ; Science ; Q
    Subject code 360
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  9. Article ; Online: Testing two types of self-help CBT-I for insomnia in older adults with arthritis or coronary artery disease.

    Rybarczyk, Bruce / Mack, Laurin / Harris, Jennifer Huang / Stepanski, Edward

    Rehabilitation psychology

    2011  Volume 56, Issue 4, Page(s) 257–266

    Abstract: Objective: The present study tested two methods of self-help cognitive-behavioral therapy for insomnia (CBT-I) for 106 older adults (mean age = 68) with osteoarthritis (n = 33) or coronary artery disease (n = 33) or no significant medical condition (n = ...

    Abstract Objective: The present study tested two methods of self-help cognitive-behavioral therapy for insomnia (CBT-I) for 106 older adults (mean age = 68) with osteoarthritis (n = 33) or coronary artery disease (n = 33) or no significant medical condition (n = 40). The latter was employed as a comparison group to test the differential efficacy between primary and comorbid insomnia.
    Method: Self-help CBT-I has demonstrated efficacy in previous studies, so two treatments were compared rather than employing a no treatment control group. Participants were randomly assigned to a book version or an enhanced multimedia version of CBT-I.
    Results: Both versions of CBT-I demonstrated efficacy in improving all measures of sleep at posttreatment, using intent-to-treat analyses. These sleep improvements were maintained among 86 treatment completers who participated in 1-year follow-up assessment. There were no significant differences in treatment response between primary (no medical condition) and comorbid insomnia participants and no significant differences between the two types of self-help according to sleep log measure. However, multimedia participants compared to book participants showed more improvement on three global sleep measures administered at posttreatment only.
    Conclusions: Although outcomes were attenuated relative to those obtained in therapist led intervention studies, the results suggest that self-help CBT-I has good potential to serve as a first-line, cost-effective treatment for both primary and comorbid insomnia in older adults.
    MeSH term(s) Aged ; Attitude to Health ; Books ; Cognitive Therapy/methods ; Coronary Artery Disease/complications ; Female ; Follow-Up Studies ; Health Behavior ; Humans ; Male ; Multimedia ; Osteoarthritis/complications ; Records as Topic ; Relaxation Therapy/methods ; Sleep Initiation and Maintenance Disorders/complications ; Sleep Initiation and Maintenance Disorders/therapy ; Treatment Outcome
    Language English
    Publishing date 2011-11
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural
    ZDB-ID 224747-1
    ISSN 1939-1544 ; 0090-5550
    ISSN (online) 1939-1544
    ISSN 0090-5550
    DOI 10.1037/a0025577
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Nitrite inhalants use and HIV infection among men who have sex with men in China.

    Li, Dongliang / Yang, Xueying / Zhang, Zheng / Qi, Xiao / Ruan, Yuhua / Jia, Yujiang / Pan, Stephen W / Xiao, Dong / Jennifer Huang, Z / Luo, Fengji / Hu, Yifei

    BioMed research international

    2014  Volume 2014, Page(s) 365261

    Abstract: Objective: This is the first study in China to examine the use of nitrite inhalants and its correlates among men who have sex with men (MSM) in Beijing, China.: Methods: A cross-sectional survey was conducted in 2012. Structured interviews collected ... ...

    Abstract Objective: This is the first study in China to examine the use of nitrite inhalants and its correlates among men who have sex with men (MSM) in Beijing, China.
    Methods: A cross-sectional survey was conducted in 2012. Structured interviews collected data on demographics, sexual and drug use behaviors, and the use of HIV services. Blood specimens were collected and tested for HIV and syphilis.
    Results: A total of 400 MSM eligible for the study were between 19 and 63 years of age and overall HIV prevalence was 6.0% (9.0% among nitrite inhalant users and 3.3% among nonusers). Nearly half (47.3%) of them reported ever using nitrite inhalants and 42.3% admitted using nitrite inhalants in the past year. Multivariable logistic analysis revealed that ever using nitrite inhalants in the past was independently associated with being aged ≤25 years, having higher education attainment, seeking sex via Internet, having casual partners in the past three months, and being HIV positive.
    Conclusion: The use of nitrite inhalants was alarmingly prevalent among MSM in Beijing. The independent association of the nitrite inhalant use with more casual sex partners and HIV infection underscored the need for intervention and prevention of nitrite inhalant use.
    MeSH term(s) Adult ; Aged ; Amyl Nitrite/poisoning ; Causality ; China/epidemiology ; Comorbidity ; HIV Infections/epidemiology ; Homosexuality, Male/statistics & numerical data ; Humans ; Illicit Drugs/poisoning ; Incidence ; Inhalant Abuse/epidemiology ; Male ; Middle Aged ; Risk Assessment ; Sexual Partners/classification ; Sexually Transmitted Diseases/epidemiology ; Unsafe Sex/statistics & numerical data ; Young Adult
    Chemical Substances Illicit Drugs ; Amyl Nitrite (8017-89-8)
    Language English
    Publishing date 2014-03-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2014/365261
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top