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  1. Article ; Online: The effectiveness of a noninterruptive alert to increase prescription of take-home naloxone in emergency departments.

    Jennings, Lindsey K / Ward, Ralph / Pekar, Ekaterina / Szwast, Elizabeth / Sox, Luke / Hying, Joseph / Mccauley, Jenna / Obeid, Jihad S / Lenert, Leslie A

    Journal of the American Medical Informatics Association : JAMIA

    2023  Volume 30, Issue 4, Page(s) 683–691

    Abstract: Objective: Opioid-related overdose (OD) deaths continue to increase. Take-home naloxone (THN), after treatment for an OD in an emergency department (ED), is a recommended but under-utilized practice. To promote THN prescription, we developed a ... ...

    Abstract Objective: Opioid-related overdose (OD) deaths continue to increase. Take-home naloxone (THN), after treatment for an OD in an emergency department (ED), is a recommended but under-utilized practice. To promote THN prescription, we developed a noninterruptive decision support intervention that combined a detailed OD documentation template with a reminder to use the template that is automatically inserted into a provider's note by decision rules. We studied the impact of the combined intervention on THN prescribing in a longitudinal observational study.
    Methods: ED encounters involving an OD were reviewed before and after implementation of the reminder embedded in the physicians' note to use an advanced OD documentation template for changes in: (1) use of the template and (2) prescription of THN. Chi square tests and interrupted time series analyses were used to assess the impact. Usability and satisfaction were measured using the System Usability Scale (SUS) and the Net Promoter Score.
    Results: In 736 OD cases defined by International Classification of Disease version 10 diagnosis codes (247 prereminder and 489 postreminder), the documentation template was used in 0.0% and 21.3%, respectively (P < .0001). The sensitivity and specificity of the reminder for OD cases were 95.9% and 99.8%, respectively. Use of the documentation template led to twice the rate of prescribing of THN (25.7% vs 50.0%, P < .001). Of 19 providers responding to the survey, 74% of SUS responses were in the good-to-excellent range and 53% of providers were Net Promoters.
    Conclusions: A noninterruptive decision support intervention was associated with higher THN prescribing in a pre-post study across a multiinstitution health system.
    MeSH term(s) Humans ; Naloxone/therapeutic use ; Narcotic Antagonists/therapeutic use ; Opioid-Related Disorders/drug therapy ; Drug Overdose ; Emergency Service, Hospital
    Chemical Substances Naloxone (36B82AMQ7N) ; Narcotic Antagonists
    Language English
    Publishing date 2023-01-31
    Publishing country England
    Document type Observational Study ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1205156-1
    ISSN 1527-974X ; 1067-5027
    ISSN (online) 1527-974X
    ISSN 1067-5027
    DOI 10.1093/jamia/ocac257
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4128: Show issues Location:
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    Zs.MO 312: Show issues

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  2. Article: Trends in Self-Reported Fentanyl and Other Illicit Substance Use in South Carolina Emergency Department Patients, 2020-2022.

    Lane, Suzanne M / Jennings, Lindsey K / Gainey, Sarah S / Barth, Kelly S / Haynes, Louise / Moreland, Angela / Hartwell, Karen / Brady, Kathleen T

    The Journal of emergency medicine

    2023  Volume 65, Issue 6, Page(s) e534–e541

    Abstract: Background: Opioid-involved deaths are continuing to increase across the United States, exceeding 100,000 for the first time in 2021. Contamination with, and intentional use of, synthetic opioids such as fentanyl are a major driver of this increase. ... ...

    Abstract Background: Opioid-involved deaths are continuing to increase across the United States, exceeding 100,000 for the first time in 2021. Contamination with, and intentional use of, synthetic opioids such as fentanyl are a major driver of this increase. Utilizing self-report substance use data of patients being treated in the emergency department (ED) can be useful to determine which substances patients are intentionally seeking.
    Objectives: 1) Examine changes in self-reported illicit substance use (including fentanyl) over time; 2) Examine changes in the co-occurrence of self-reported fentanyl with other illicit substance use over time.
    Methods: All patients presenting to the study EDs that answered anything other than "never" on the National Institute on Drug Abuse Quick Screen and were seen by a peer recovery specialist in the ED between July 1, 2020 and December 31, 2022 were included for analysis. The substance of use as reported by each patient was recorded by the peer recovery specialist. Differences in substance use by type over time were examined using chi-squared tests of proportions.
    Results: There were 7568 patients that met inclusion criteria. Self-reported fentanyl (1760%; p < 0.0001) and cocaine (82%; p = 0.034) use increased, whereas heroin use (16%; p < 0.0001) decreased.
    Conclusions: Self-reported fentanyl and cocaine use has increased significantly in South Carolina ED patients between 2020 and 2022. Given the high morbidity and mortality associated with fentanyl and fentanyl analog use, further measures to identify these patients and provide harm reduction and treatment from the ED setting are warranted.
    MeSH term(s) Humans ; United States ; Fentanyl ; Self Report ; South Carolina/epidemiology ; Opioid-Related Disorders ; Drug Overdose/epidemiology ; Analgesics, Opioid/therapeutic use ; Heroin ; Cocaine ; Emergency Service, Hospital
    Chemical Substances Fentanyl (UF599785JZ) ; Analgesics, Opioid ; Heroin (70D95007SX) ; Cocaine (I5Y540LHVR)
    Language English
    Publishing date 2023-08-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605559-x
    ISSN 0736-4679
    ISSN 0736-4679
    DOI 10.1016/j.jemermed.2023.08.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1895: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Characterization of peer support services for substance use disorders in 11 US emergency departments in 2020: findings from a NIDA clinical trials network site selection process.

    Jennings, Lindsey K / Lander, Laura / Lawdahl, Tricia / McClure, Erin A / Moreland, Angela / McCauley, Jenna L / Haynes, Louise / Matheson, Timothy / Jones, Richard / Robey, Thomas E / Kawasaki, Sarah / Moschella, Phillip / Raheemullah, Amer / Miller, Suzette / Gregovich, Gina / Waltman, Deborah / Brady, Kathleen T / Barth, Kelly S

    Addiction science & clinical practice

    2024  Volume 19, Issue 1, Page(s) 26

    Abstract: Introduction: Emergency departments (ED) are incorporating Peer Support Specialists (PSSs) to help with patient care for substance use disorders (SUDs). Despite rapid growth in this area, little is published regarding workflow, expectations of the peer ... ...

    Abstract Introduction: Emergency departments (ED) are incorporating Peer Support Specialists (PSSs) to help with patient care for substance use disorders (SUDs). Despite rapid growth in this area, little is published regarding workflow, expectations of the peer role, and core components of the PSS intervention. This study describes these elements in a national sample of ED-based peer support intervention programs.
    Methods: A survey was conducted to assess PSS site characteristics as part of site selection process for a National Institute on Drug Abuse (NIDA) Clinical Trials Network (CTN) evaluating PSS effectiveness, Surveys were distributed to clinical sites affiliated with the 16 CTN nodes. Surveys were completed by a representative(s) of the site and collected data on the PSS role in the ED including details regarding funding and certification, services rendered, role in medications for opioid use disorder (MOUD) and naloxone distribution, and factors impacting implementation and maintenance of ED PSS programs. Quantitative data was summarized with descriptive statistics. Free-text fields were analyzed using qualitative content analysis.
    Results: A total of 11 surveys were completed, collected from 9 different states. ED PSS funding was from grants (55%), hospital funds (46%), peer recovery organizations (27%) or other (18%). Funding was anticipated to continue for a mean of 16 months (range 12 to 36 months). The majority of programs provided "general recovery support (81%) Screening, Brief Intervention, and Referral to Treatment (SBIRT) services (55%), and assisted with naloxone distribution to ED patients (64%). A minority assisted with ED-initiated buprenorphine (EDIB) programs (27%). Most (91%) provided services to patients after they were discharged from the ED. Barriers to implementation included lack of outpatient referral sources, barriers to initiating MOUD, stigma at the clinician and system level, and lack of ongoing PSS availability due to short-term grant funding.
    Conclusions: The majority of ED-based PSSs were funded through time-limited grants, and short-term grant funding was identified as a barrier for ED PSS programs. There was consistency among sites in the involvement of PSSs in facilitation of transitions of SUD care, coordination of follow-up after ED discharge, and PSS involvement in naloxone distribution.
    MeSH term(s) United States ; Humans ; National Institute on Drug Abuse (U.S.) ; Emergency Service, Hospital ; Naloxone/therapeutic use ; Opioid-Related Disorders/drug therapy ; Nitrosamines
    Chemical Substances N-nitrosoiminodiacetic acid (25081-31-6) ; Naloxone (36B82AMQ7N) ; Nitrosamines
    Language English
    Publishing date 2024-04-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2492632-2
    ISSN 1940-0640 ; 1940-0640
    ISSN (online) 1940-0640
    ISSN 1940-0640
    DOI 10.1186/s13722-024-00453-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Retention in Treatment after Emergency Department-Initiated Buprenorphine.

    Jennings, Lindsey K / Lane, Suzanne / McCauley, Jenna / Moreland, Angela / Hartwell, Karen / Haynes, Louise / Barth, Kelly S / Gainey, Sarah S / Brady, Kathleen T

    The Journal of emergency medicine

    2021  Volume 61, Issue 3, Page(s) 211–221

    Abstract: Background: Emergency department-initiated buprenorphine (EDIB) has been shown to be effective in connecting patients with opioid use disorder (OUD) to outpatient treatment. Five diverse emergency departments (EDs) have successfully implemented EDIB ... ...

    Abstract Background: Emergency department-initiated buprenorphine (EDIB) has been shown to be effective in connecting patients with opioid use disorder (OUD) to outpatient treatment. Five diverse emergency departments (EDs) have successfully implemented EDIB programs.
    Objectives: 1) To measure attendance at the first referral appointment and 30-day retention in treatment rates for patients receiving EDIB; 2) To describe demographic and opioid use characteristics of patients receiving EDIB; and 3) To determine average length of time in treatment after EDIB at the five participating EDs.
    Methods: All patients receiving EDIB at the participating EDs (n = 522) were seen by a peer recovery specialist in the ED and demographic and opioid use characteristics were recorded. Patients were followed prospectively. The referral site was contacted and information regarding attendance at the first referral appointment and 30-day retention in treatment was obtained. All patients still in treatment at 30 days were continually followed at subsequent 30-day intervals until the referral site indicated the patient had ended treatment at their facility.
    Results: The rate of attendance at the first referral appointment was 77.0% for patients receiving EDIB. At 30-day follow-up, 43.1% of patients were retained in treatment. The mean age of patient enrollment was 36.7 years, 58% of enrollees were male, 90.5% were white, and 73.4% had no medical insurance. Seventy-seven percent reported no substance use other than opioids. The mean time in treatment was 158 days.
    Conclusions: EDIB programs across diverse ED settings are effective at promoting attendance at the first referral appointment for OUD treatment; however, additional work is warranted to increase 30-day treatment retention rates, particularly among patients with nonprescription-only use profiles.
    MeSH term(s) Adult ; Buprenorphine/therapeutic use ; Emergency Service, Hospital ; Humans ; Male ; Opiate Substitution Treatment ; Opioid-Related Disorders/drug therapy ; Referral and Consultation
    Chemical Substances Buprenorphine (40D3SCR4GZ)
    Language English
    Publishing date 2021-06-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605559-x
    ISSN 0736-4679
    ISSN 0736-4679
    DOI 10.1016/j.jemermed.2021.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1895: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Rates of substance use disorder treatment seeking visits after emergency department-initiated buprenorphine.

    Jennings, Lindsey K / Bogan, Carolyn / McCauley, Jenna J / Moreland, Angela / Lane, Suzanne / Ward, Ralph / Hartwell, Karen J / Haynes, Louise / Brady, Kathleen T

    The American journal of emergency medicine

    2020  Volume 38, Issue 5, Page(s) 975–978

    Abstract: Background: Emergency department-initiated buprenorphine (EDIB) programs have been shown to improve treatment outcomes for patients with opioid use disorders (OUD); however, little is known about how EDIB implementation impacts the patient census at ... ...

    Abstract Background: Emergency department-initiated buprenorphine (EDIB) programs have been shown to improve treatment outcomes for patients with opioid use disorders (OUD); however, little is known about how EDIB implementation impacts the patient census at participating hospitals.
    Objectives: To determine if implementation of an EDIB program was associated with changes in the number of patients presenting to the ED seeking treatment for substance use disorder (SUD).
    Methods: We conducted a retrospective evaluation at a single academic ED that began offering EDIB in December 2017. Data span the period of December 2016 to April 2019, All ED visits with a chief complaint of addiction problem, detoxification, drug/alcohol assessment, drug problem, or withdrawal charted by nursing at the time of triage were eligible for inclusion. Charts were reviewed to determine: (1) treatment status and (2) substance(s) for which the patient was seeking treatment. An interrupted time series analysis was used to compare the pre- and post-EDIB rates for all-substance, as well as opioid-specific, treatment-seeking visits.
    Results: For all-substance visits, the predicted level change in the treatment-seeking rate after EDIB was implemented was positive but not significant (0.000497, p = 0.53); the trend change after EDIB was also not significant (-0.00004, p = 0.73). For visits involving opioids, the predicted level change was (0.000638, p = 0.21); and the trend change was (0.000047, p = 0.49).
    Conclusion: Implementation of an EDIB program was not associated with increased rates of presentation by patients requesting treatment for a substance use disorder in the participating ED setting.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Buprenorphine/therapeutic use ; Emergency Service, Hospital ; Female ; Humans ; Interrupted Time Series Analysis ; Male ; Middle Aged ; Narcotic Antagonists/therapeutic use ; Opiate Substitution Treatment ; Opioid-Related Disorders/drug therapy ; Patient Acceptance of Health Care/statistics & numerical data ; Retrospective Studies ; Young Adult
    Chemical Substances Narcotic Antagonists ; Buprenorphine (40D3SCR4GZ)
    Language English
    Publishing date 2020-02-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2020.02.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2005: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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