LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 46

Search options

  1. Article ; Online: A Healthy Dose of Price Transparency in US Health Care Services.

    Jenny, Hillary E / Jenny, Brenna E

    JAMA surgery

    2020  Volume 155, Issue 7, Page(s) 544–545

    MeSH term(s) Commerce ; Disclosure ; Health Services/economics ; United States
    Language English
    Publishing date 2020-05-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701841-6
    ISSN 2168-6262 ; 2168-6254
    ISSN (online) 2168-6262
    ISSN 2168-6254
    DOI 10.1001/jamasurg.2020.0754
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Data-Driven Insights on the Effects of COVID-19 on Public Interest in Medical Aesthetics: Part II (Active Analysis).

    Jenny, Hillary E / Chandawarkar, Akash / Kim, Roy

    Aesthetic surgery journal

    2020  Volume 41, Issue 3, Page(s) NP75–NP82

    Abstract: Background: The COVID-19 pandemic significantly affected financial and psychosocial factors that influence plastic surgery demand.: Objectives: The authors sought to actively assess public interest changes and the reasons underlying these shifts.: ... ...

    Abstract Background: The COVID-19 pandemic significantly affected financial and psychosocial factors that influence plastic surgery demand.
    Objectives: The authors sought to actively assess public interest changes and the reasons underlying these shifts.
    Methods: Using Amazons' Mechanical Turk, we crowdsourced public opinions regarding aesthetic interventions from April 30 to May 3, 2020. The survey assessed prior experience with and interest in 6 aesthetic interventions before and during the pandemic and reasons for changing interest. United States residents aged 18 years and over who passed the attention check were included.
    Results: We included 704 of 838 total responses. One-half of respondents were female; the median age group was 25 to 34 years. During the pandemic, 21% of respondents had increased and 33% decreased interest in at least one intervention. Non-invasive procedures (7.3%), facial aesthetic surgery (6.6%), and medical-grade skincare (5.9%) elicited the greatest interest increase. Seeing themselves in the mirror more often (43.2%), desire to look better after the crisis (41.8%), and increased time on social media (40.4%) were the top reasons for increased interest. The most common reasons for decreased interest were changing spending priorities (58%), focusing on other health aspects (49.8%), and worrying about infection in medical facilities (46.3%). Almost one-half of respondents considered virtual consultations for interventions of increased interest.
    Conclusions: The COVID-19 pandemic significantly affected interest in medical aesthetics. Offering telemedicine and discussing detailed COVID-19 infection control policies with patients will be critical to address patient needs and concerns. These findings can be used to improve patient outreach, advertisement, and counseling as practices focus on reopening.
    MeSH term(s) Adolescent ; Adult ; COVID-19 ; Esthetics ; Female ; Humans ; Pandemics ; SARS-CoV-2 ; Surgery, Plastic ; Telemedicine ; United States
    Keywords covid19
    Language English
    Publishing date 2020-11-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2087022-X
    ISSN 1527-330X ; 1090-820X ; 1084-0761
    ISSN (online) 1527-330X
    ISSN 1090-820X ; 1084-0761
    DOI 10.1093/asj/sjaa173
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: In vivo

    McClain, Shannan P / Ma, Xiang / Johnson, Desiree A / Johnson, Caroline A / Layden, Aryanna E / Yung, Jean C / Lubejko, Susan T / Livrizzi, Giulia / Jenny He, X / Zhou, Jingjing / Ventriglia, Emilya / Rizzo, Arianna / Levinstein, Marjorie / Gomez, Juan L / Bonaventura, Jordi / Michaelides, Michael / Banghart, Matthew R

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Traditional methods for site-specific drug delivery in the brain are slow, invasive, and difficult to interface with recordings of neural activity. Here, we demonstrate the feasibility and experimental advantages of : Highlights: A photoactivatable ... ...

    Abstract Traditional methods for site-specific drug delivery in the brain are slow, invasive, and difficult to interface with recordings of neural activity. Here, we demonstrate the feasibility and experimental advantages of
    Highlights: A photoactivatable opioid agonist (PhOX) and antagonist (PhNX) for
    Language English
    Publishing date 2023-02-03
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.02.02.526901
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: National Trends in Pediatric Facial Fractures: The Impact of Health Care Policy.

    Jenny, Hillary E / Yesantharao, Pooja / Redett, Richard J / Yang, Robin

    Plastic and reconstructive surgery

    2020  Volume 147, Issue 2, Page(s) 432–441

    Abstract: Background: Traumatic injuries are significant sources of morbidity and mortality in the pediatric population. Using a national database, this study aims to characterize pediatric facial fracture management and the effect of health care policy changes ... ...

    Abstract Background: Traumatic injuries are significant sources of morbidity and mortality in the pediatric population. Using a national database, this study aims to characterize pediatric facial fracture management and the effect of health care policy changes on populations receiving treatment.
    Methods: A retrospective cohort study was performed using Healthcare Cost and Utilization Project Kids' Inpatient Database databases from 2000 to 2016. Pediatric patients admitted with a facial fracture diagnosis were included. Clinical outcomes include mortality, reduction of fracture during hospital stay, and open fracture reduction. The impact of the Affordable Care Act on patient demographics and management was assessed.
    Results: Between 2000 and 2016, 82,414 patients were managed for facial fractures, 8.3 percent of whom were managed after implementation of the Affordable Care Act (n = 6841). Mean age was 15.2 years, and the male-to-female ratio was 2.9:1. Significant racial disparities were identified before the Affordable Care Act: African American and Native American patients had decreased odds of having facial fracture reduction during the initial hospital stay (OR, 0.84 and 0.86, respectively), and identifying as either Hispanic or Native American was associated with higher odds of mortality (OR, 1.4 or 2.4, respectively). Race was not contributory to patient mortality after the Affordable Care Act. Before Affordable Care Act implementation, patients receiving care with no charge (including charity care/charity research) had lower odds of having an open reduction or any reduction; insurance status was not contributory to management after the Affordable Care Act.
    Conclusion: Although the Affordable Care Act may have increased access to care for certain populations, race- and sex-associated differences in mortality rate and fracture management should be further investigated to ensure a national standard of equitable patient care.
    MeSH term(s) Adolescent ; Child ; Child, Preschool ; Databases, Factual/statistics & numerical data ; Facial Bones/injuries ; Facial Bones/surgery ; Female ; Health Policy ; Healthcare Disparities/economics ; Healthcare Disparities/statistics & numerical data ; Healthcare Disparities/trends ; Hospital Mortality/trends ; Humans ; Insurance Coverage/statistics & numerical data ; Length of Stay/statistics & numerical data ; Length of Stay/trends ; Male ; Minority Groups/statistics & numerical data ; Patient Acceptance of Health Care/statistics & numerical data ; Patient Protection and Affordable Care Act/economics ; Patient Protection and Affordable Care Act/statistics & numerical data ; Patient Protection and Affordable Care Act/trends ; Retrospective Studies ; Skull Fractures/economics ; Skull Fractures/mortality ; Skull Fractures/surgery ; United States/epidemiology ; Young Adult
    Language English
    Publishing date 2020-11-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0000000000007537
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Safety of Irradiated Homologous Costal Cartilage Graft in Cleft Rhinoplasty.

    Jenny, Hillary E / Siegel, Nicholas / Yang, Robin / Redett, Richard J

    Plastic and reconstructive surgery

    2020  Volume 147, Issue 1, Page(s) 76e–81e

    Abstract: Background: Autologous cartilage grafts have a low risk of infection and extrusion in cleft rhinoplasty. However, harvesting autologous cartilage involves donor-site morbidity and increased time under anesthesia. Irradiated homologous costal cartilage ... ...

    Abstract Background: Autologous cartilage grafts have a low risk of infection and extrusion in cleft rhinoplasty. However, harvesting autologous cartilage involves donor-site morbidity and increased time under anesthesia. Irradiated homologous costal cartilage grafts may be an effective alternative.
    Methods: A retrospective study was performed on patients with a history of cleft lip who underwent rhinoplasty for cleft nasal deformity at Johns Hopkins Hospital from 2009 to 2018. Patients were excluded if their rhinoplasty did not involve a cartilage graft.
    Results: One hundred sixty-five cleft rhinoplasties (patient age, 2 to 72 years; 52 percent female) were performed. Median follow-up time was 256 days; 30 percent were revision operations. Ninety-six procedures (58 percent) used irradiated homologous costal cartilage grafts, with the remaining using autologous cartilage. Complications resulted from 18 procedures (11 percent), seven (10 percent) involving autologous cartilage and 11 (12 percent) involving irradiated homologous costal cartilage. Most autologous cartilage complications (86 percent) required operative intervention, versus seven of 11 (64 percent) for irradiated homologous costal cartilage. Complications associated with irradiated homologous costal cartilage included infection (n = 5), warping (n = 2), and extrusion (n = 1), while two patients with autologous cartilage experienced collapse and one each experienced resorption, warping, and hypertrophic donor-site scarring. There was no difference between groups regarding complication rate or complications requiring operative intervention (p = 0.3 and p = 0.5, respectively).
    Conclusions: Irradiated homologous costal cartilage grafts are equally safe and effective as autologous cartilage for use in cleft rhinoplasty. These grafts are readily available and eliminate donor-site morbidity.
    Clinical question/level of evidence: Therapeutic, III.
    MeSH term(s) Adolescent ; Adult ; Aged ; Autografts/microbiology ; Autografts/transplantation ; Cadaver ; Child ; Child, Preschool ; Cleft Lip/surgery ; Costal Cartilage/radiation effects ; Costal Cartilage/transplantation ; Female ; Follow-Up Studies ; Heterografts/microbiology ; Heterografts/transplantation ; Humans ; Male ; Middle Aged ; Patient Satisfaction/statistics & numerical data ; Reoperation/statistics & numerical data ; Retrospective Studies ; Rhinoplasty/adverse effects ; Rhinoplasty/methods ; Rhinoplasty/statistics & numerical data ; Sterilization/methods ; Surgical Wound Infection/epidemiology ; Surgical Wound Infection/microbiology ; Surgical Wound Infection/prevention & control ; Tissue and Organ Harvesting/methods ; Transplantation, Autologous/adverse effects ; Transplantation, Autologous/statistics & numerical data ; Transplantation, Homologous/adverse effects ; Transplantation, Homologous/methods ; Transplantation, Homologous/statistics & numerical data ; Young Adult
    Language English
    Publishing date 2020-12-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0000000000007431
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Public Perceptions of Physician Attire and Professionalism in the US.

    Xun, Helen / Chen, Jonlin / Sun, Alexander H / Jenny, Hillary E / Liang, Fan / Steinberg, Jordan P

    JAMA network open

    2021  Volume 4, Issue 7, Page(s) e2117779

    Abstract: Importance: In recent years, casual physician attire (fleece jackets and softshell jackets) has become increasingly popular, but to our knowledge, public perceptions of these garments have not been studied. Furthermore, gender biases may result in ... ...

    Abstract Importance: In recent years, casual physician attire (fleece jackets and softshell jackets) has become increasingly popular, but to our knowledge, public perceptions of these garments have not been studied. Furthermore, gender biases may result in differing expectations and perceptions of female and male physicians and may be associated with patient rapport and trust building.
    Objective: To characterize public perceptions of casual physician attire and implicit gender biases in public assessment of physicians' professional attire.
    Design, setting, and participants: This survey study used a population-based survey administered via Amazon Mechanical Turk from May to June 2020 among individuals aged 18 years or older who were US residents and for whom English was the primary language.
    Intervention: Survey featuring photographs of a male or female model wearing various types of physician attire (white coat, business attire, and scrubs).
    Main outcomes and measures: Respondents' ratings of professionalism, experience, and friendliness of the male and female models in various attire and perceptions of the models' most likely health care profession. Preference scores for various outfits were calculated as the difference between the preference score for an outfit and the mean preference score for the outfit-role pairing.
    Results: Of 522 surveys completed, 487 were included for analysis; the mean (SD) age of respondents was 36.2 (12.4) years, 260 (53.4%) were female, and 372 (76.4%) were White individuals. Respondents perceived models of health care professionals wearing white coats vs those wearing fleece or softshell jackets as significantly more experienced (mean [SD] experience score: white coat, 4.9 [1.5]; fleece, 3.1 [1.5]; softshell, 3.1 [1.5]; P < .001) and professional (mean [SD] professionalism score: white coat, 4.9 [1.6]; fleece, 3.2 [1.5]; softshell, 3.3 [1.5]; P < .001). A white coat with scrubs attire was most preferred for surgeons (mean [SD] preference index: 1.3 [2.3]), whereas a white coat with business attire was preferred for family physicians and dermatologists (mean [SD] preference indexes, 1.6 [2.3] and 1.2 [2.3], respectively; P < .001). Regardless of outerwear, female models in business attire as inner wear were rated as less professional than male counterparts (mean [SD] professionalism score: male, 65.8 [25.4]; female, 56.2 [20.2]; P < .001). Both the male and the female model were identified by the greater number of respondents as a physician or surgeon; however, the female model vs the male model was mistaken by more respondents as a medical technician (39 [8.0] vs 16 [3.3%]; P < .005), physician assistant (56 [11.5%] vs 11 [2.3%]; P < .001), or nurse (161 [33.1%] vs 133 [27.3%]; P = .050).
    Conclusions and relevance: In this survey study, survey respondents rated physicians wearing casual attire as less professional and experienced than those wearing a white coat. Gender biases were found in impressions of professionalism, with female physicians' roles being more frequently misidentified. Understanding disparate public perceptions of physician apparel may inform interventions to address professional role confusion and cumulative career disadvantages for women in medicine.
    MeSH term(s) Adult ; Clothing/psychology ; Female ; Health Personnel/psychology ; Humans ; Male ; Physician's Role/psychology ; Physician-Patient Relations ; Physicians/psychology ; Physicians, Women/psychology ; Professionalism ; Public Opinion ; Sexism/psychology ; Trust ; United States
    Language English
    Publishing date 2021-07-01
    Publishing country United States
    Document type Journal Article
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2021.17779
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Characterizing the Global Need for Plastic Surgery Service.

    Ma, Xiya / Long, Chao / Rai, Sushant / Pradhan, Rohan / Jenny, Hillary E

    Plastic and reconstructive surgery

    2021  Volume 147, Issue 5, Page(s) 905e–906e

    MeSH term(s) Humans ; Internship and Residency ; Plastic Surgery Procedures ; Surgery, Plastic/education
    Language English
    Publishing date 2021-04-20
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0000000000007859
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article: Data-Driven Insights on the Effects of COVID-19 on Public Interest in Medical Aesthetics: Part II (Active Analysis)

    Jenny, Hillary E / Chandawarkar, Akash / Kim, Roy

    Abstract: BACKGROUND: The COVID-19 pandemic significantly affected financial and psychosocial factors that influence plastic surgery demand. OBJECTIVES: The authors sought to actively assess public interest changes and the reasons underlying these shifts. METHODS: ...

    Abstract BACKGROUND: The COVID-19 pandemic significantly affected financial and psychosocial factors that influence plastic surgery demand. OBJECTIVES: The authors sought to actively assess public interest changes and the reasons underlying these shifts. METHODS: Using Amazons' Mechanical Turk, we crowdsourced public opinions regarding aesthetic interventions from April 30 to May 3, 2020. The survey assessed prior experience with and interest in 6 aesthetic interventions before and during the pandemic and reasons for changing interest. United States residents aged 18 years and over who passed the attention check were included. RESULTS: We included 704 of 838 total responses. One-half of respondents were female; the median age group was 25 to 34 years. During the pandemic, 21% of respondents had increased and 33% decreased interest in at least one intervention. Non-invasive procedures (7.3%), facial aesthetic surgery (6.6%), and medical-grade skincare (5.9%) elicited the greatest interest increase. Seeing themselves in the mirror more often (43.2%), desire to look better after the crisis (41.8%), and increased time on social media (40.4%) were the top reasons for increased interest. The most common reasons for decreased interest were changing spending priorities (58%), focusing on other health aspects (49.8%), and worrying about infection in medical facilities (46.3%). Almost one-half of respondents considered virtual consultations for interventions of increased interest. CONCLUSIONS: The COVID-19 pandemic significantly affected interest in medical aesthetics. Offering telemedicine and discussing detailed COVID-19 infection control policies with patients will be critical to address patient needs and concerns. These findings can be used to improve patient outreach, advertisement, and counseling as practices focus on reopening.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #892072
    Database COVID19

    Kategorien

  9. Article ; Online: Data-Driven Insights on the Effects of COVID-19 on Public Interest in Medical Aesthetics

    Jenny, Hillary E / Chandawarkar, Akash / Kim, Roy

    Aesthetic Surgery Journal ; ISSN 1090-820X 1527-330X

    Part II (Active Analysis)

    2020  

    Abstract: Abstract Background The COVID-19 pandemic significantly affected financial and psychosocial factors that influence plastic surgery demand. Objectives The authors sought to actively assess public interest changes and the reasons underlying these shifts. ... ...

    Abstract Abstract Background The COVID-19 pandemic significantly affected financial and psychosocial factors that influence plastic surgery demand. Objectives The authors sought to actively assess public interest changes and the reasons underlying these shifts. Methods Using Amazons’ Mechanical Turk, we crowdsourced public opinions regarding aesthetic interventions from April 30 to May 3, 2020. The survey assessed prior experience with and interest in 6 aesthetic interventions before and during the pandemic and reasons for changing interest. United States residents aged 18 years and over who passed the attention check were included. Results We included 704 of 838 total responses. One-half of respondents were female; the median age group was 25 to 34 years. During the pandemic, 21% of respondents had increased and 33% decreased interest in at least one intervention. Non-invasive procedures (7.3%), facial aesthetic surgery (6.6%), and medical-grade skincare (5.9%) elicited the greatest interest increase. Seeing themselves in the mirror more often (43.2%), desire to look better after the crisis (41.8%), and increased time on social media (40.4%) were the top reasons for increased interest. The most common reasons for decreased interest were changing spending priorities (58%), focusing on other health aspects (49.8%), and worrying about infection in medical facilities (46.3%). Almost one-half of respondents considered virtual consultations for interventions of increased interest. Conclusions The COVID-19 pandemic significantly affected interest in medical aesthetics. Offering telemedicine and discussing detailed COVID-19 infection control policies with patients will be critical to address patient needs and concerns. These findings can be used to improve patient outreach, advertisement, and counseling as practices focus on reopening.
    Keywords Surgery ; General Medicine ; covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    DOI 10.1093/asj/sjaa173
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  10. Article ; Online: Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons

    Xinyi Jenny He / Janki Patel / Connor E Weiss / Xiang Ma / Brenda L Bloodgood / Matthew R Banghart

    eLife, Vol

    2021  Volume 10

    Abstract: Functional interactions between G protein-coupled receptors are poised to enhance neuronal sensitivity to neuromodulators and therapeutic drugs. Mu and delta opioid receptors (MORs and DORs) can interact when overexpressed in the same cells, but whether ... ...

    Abstract Functional interactions between G protein-coupled receptors are poised to enhance neuronal sensitivity to neuromodulators and therapeutic drugs. Mu and delta opioid receptors (MORs and DORs) can interact when overexpressed in the same cells, but whether co-expression of endogenous MORs and DORs in neurons leads to functional interactions is unclear. Here, in mice, we show that both MORs and DORs inhibit parvalbumin-expressing basket cells (PV-BCs) in hippocampal CA1 through partially occlusive signaling pathways that terminate on somato-dendritic potassium channels and presynaptic calcium channels. Using photoactivatable opioid neuropeptides, we find that DORs dominate the response to enkephalin in terms of both ligand sensitivity and kinetics, which may be due to relatively low expression levels of MOR. Opioid-activated potassium channels do not show heterologous desensitization, indicating that MORs and DORs signal independently. In a direct test for heteromeric functional interactions, the DOR antagonist TIPP-Psi does not alter the kinetics or potency of either the potassium channel or synaptic responses to photorelease of the MOR agonist [d-Ala2, NMe-Phe4, Gly-ol5]enkephalin (DAMGO). Thus, aside from largely redundant and convergent signaling, MORs and DORs do not functionally interact in PV-BCs in a way that impacts somato-dendritic potassium currents or synaptic transmission. These findings imply that cross-talk between MORs and DORs, either in the form of physical interactions or synergistic intracellular signaling, is not a preordained outcome of co-expression in neurons.
    Keywords neuropeptide ; GPCR ; opioid ; heteromer ; neuromodulation ; enkephalin ; Medicine ; R ; Science ; Q ; Biology (General) ; QH301-705.5
    Subject code 572
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher eLife Sciences Publications Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

To top