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  1. Article ; Online: Shinorine and porphyra-334 isolated from laver (

    Choi, Su-Young / Lee, Su Yeon / Kim, Hyung Gyun / Jeong, Jae Cheon / Batara, Don Carlo / Kim, Sung-Hak / Cho, Jeong-Yong

    Food science and biotechnology

    2022  Volume 31, Issue 5, Page(s) 617–625

    Abstract: Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 ... ...

    Abstract Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from
    Language English
    Publishing date 2022-03-28
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2000008-X
    ISSN 2092-6456 ; 1226-7708
    ISSN (online) 2092-6456
    ISSN 1226-7708
    DOI 10.1007/s10068-022-01055-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Shinorine and porphyra-334 isolated from laver (Porphyra dentata) inhibit adipogenesis in 3T3-L1 cells

    Choi, Su-Young / Lee, Su Yeon / Kim, Hyung Gyun / Jeong, Jae Cheon / Batara, Don Carlo / Kim, Sung-Hak / Cho, Jeong-Yong

    Food science and biotechnology. 2022 May, v. 31, no. 5

    2022  

    Abstract: Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from Porphyra spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined ...

    Abstract Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from Porphyra spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined in vitro utilizing 3T3-L1 preadipocytes. Shinorine and porphyra-334 were extracted from laver (Porphyra dentata) 50% methanolic (MeOH) extract of and their structures were elucidated by MS and NMR spectroscopy. Both compounds had no cytotoxic effect in 3T3-L1 cells (< 200 μg/mL) and inhibited the accumulation of lipid droplets in 3T3-L1 mature adipocytes in a dose-dependent manner (0.1 and 1.0 μM). Interestingly, both compounds had also significantly reduced the expression of adipogenic-related genes such as peroxisome proliferator-activated receptor γ2 (PPARγ2), CCAAT/enhancer-binding protein α (C/EBPα), adiponectin, and leptin in 3T3-L1 cells. The findings suggest that shinorine and porphyra-334 have the potential to inhibit adipogenesis in 3T3-L1 preadipocytes.
    Keywords Porphyra ; adipocytes ; adipogenesis ; adiponectin ; antioxidants ; biotechnology ; cytotoxicity ; dose response ; edible seaweed ; food science ; leptin ; lipids ; nuclear magnetic resonance spectroscopy ; radiation resistance
    Language English
    Dates of publication 2022-05
    Size p. 617-625.
    Publishing place Springer Nature Singapore
    Document type Article
    ZDB-ID 2000008-X
    ISSN 1226-7708
    ISSN 1226-7708
    DOI 10.1007/s10068-022-01055-6
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Clinical and radiographic features of adult-onset ankylosing spondylitis in Korean patients: comparisons between males and females.

    Jung, Young-Ok / Kim, Inje / Kim, Suho / Suh, Chang-Hee / Park, Han Jung / Park, Won / Kwon, Seoung Ryul / Jeong, Jae Cheon / Lee, Yun Jong / Ryu, Hee Jung / Park, Young Bae / Lee, Jisoo / Lee, You-Hyun / Seo, Young Il / Chung, Won Tae / Hong, Seung-Jae / Hong, Yeon-Sik / Baek, Han Joo / Choi, Hyo Jin /
    Kang, Hyo-Jong / Lee, Chan-Hee / Kim, Sang-Hyon / Kim, Hyun Ah

    Journal of Korean medical science

    2010  Volume 25, Issue 4, Page(s) 532–535

    Abstract: The objective of this study was to investigate clinical and radiographic features and gender differences in Korean patients with adult-onset ankylosing spondylitis. Multicenter cross-sectional studies were conducted in the rheumatology clinics of 13 ... ...

    Abstract The objective of this study was to investigate clinical and radiographic features and gender differences in Korean patients with adult-onset ankylosing spondylitis. Multicenter cross-sectional studies were conducted in the rheumatology clinics of 13 Korean tertiary referral hospitals. All patients had a confirmed diagnosis of ankylosing spondylitis according to the modified New York criteria. Clinical, laboratory, and radiographic features were evaluated and disease activities were assessed using the Bath ankylosing spondylitis disease activity index. Five hundred and five patients were recruited. The male to female ratio was 6.1:1. Average age at symptom onset was 25.4+/-8.9 yr and average disease duration was 9.6+/-6.8 yr. Males manifested symptoms at a significantly earlier age. HLA-B27 was more frequently positive in males. Hips were more commonly affected in males, and knees in females. When spinal mobility was measured using tragus-to-wall distance and the modified Schober's test, females had significantly better results. Radiographic spinal changes, including bamboo spine and syndesmophytes, were more common in males after adjustment of confounding factors. In conclusion, we observed significant gender differences in radiographic spinal involvement as well as other clinical manifestations among Korea patients with adult-onset ankylosing spondylitis. These findings may influence the timing of the diagnosis and the choice of treatment.
    MeSH term(s) Adult ; Age of Onset ; Asian Continental Ancestry Group ; Female ; HLA-B27 Antigen ; Humans ; Joints/pathology ; Male ; Radiography ; Severity of Illness Index ; Spondylitis, Ankylosing/diagnosis ; Spondylitis, Ankylosing/diagnostic imaging ; Spondylitis, Ankylosing/pathology ; Spondylitis, Ankylosing/physiopathology
    Chemical Substances HLA-B27 Antigen
    Language English
    Publishing date 2010-03-19
    Publishing country Korea (South)
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639262-3
    ISSN 1598-6357 ; 1011-8934
    ISSN (online) 1598-6357
    ISSN 1011-8934
    DOI 10.3346/jkms.2010.25.4.532
    Database MEDical Literature Analysis and Retrieval System OnLINE

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