Article ; Online: Assessment of protein–protein interfaces in cryo-EM derived assemblies
Nature Communications, Vol 12, Iss 1, Pp 1-
2021 Volume 12
Abstract: Here, the authors present Protein Interface-score (PI-score), a machine learning-based metric that has been trained on protein–protein interfaces’ features from high-resolution crystal structures. They use the PI-score to evaluate the protein–protein ... ...
| Abstract | Here, the authors present Protein Interface-score (PI-score), a machine learning-based metric that has been trained on protein–protein interfaces’ features from high-resolution crystal structures. They use the PI-score to evaluate the protein–protein interfaces in more than 1000 PDB-deposited cryo-EM structures and show that it can be used as a complementary assessment tool for cryo-EM model validation. |
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| Keywords | Science ; Q |
| Language | English |
| Publishing date | 2021-06-01T00:00:00Z |
| Publisher | Nature Portfolio |
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
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