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  1. Article ; Online: Cancer Pain Management with Traditional Chinese Medicine: Current Status and Future Perspectives.

    Ji, Jiafu / Guo, Jingxuan / Chi, Yongliang / Su, Fan

    The American journal of Chinese medicine

    2024  Volume 52, Issue 1, Page(s) 123–135

    Abstract: Cancer pain, especially the moderate-to-severe pain experienced by patients with advanced cancer, is still one of the most challenging clinical problems. The current mainstream pharmacological treatment for cancer pain involves applying opioid ... ...

    Abstract Cancer pain, especially the moderate-to-severe pain experienced by patients with advanced cancer, is still one of the most challenging clinical problems. The current mainstream pharmacological treatment for cancer pain involves applying opioid medications and other pain-killing drugs. However, analgesic drugs have many adverse effects such as addiction, tolerance, and other formidable clinical and social issues. Thus, finding a new therapeutic approach to treat cancer pain is essential. Traditional Chinese medicine (TCM) has been increasingly applied in clinical practice because of its good efficacy and few side effects. However, its mechanisms of action in treating pain are still under investigation. The most important mechanism of cancer pain is that a large amount of pain-causing substances are secreted from cancer cells and promote their growth and invasion. The physical and chemical stimulations of these substances exist along with the cancer growth, leading to constantly increased pain sensation. Whether cancer pain can be alleviated by inhibiting cancer cells from releasing the substances and changing the microenvironment around the cancer mass, or even by eliminating pain-causing substances, is largely unknown. Based on TCM theory, this study reported that the aforementioned approach could effectively manage different cancer pains by tonifying
    MeSH term(s) Humans ; Medicine, Chinese Traditional ; Pain Management ; Cancer Pain/drug therapy ; Cancer Pain/etiology ; Quality of Life ; Drugs, Chinese Herbal/pharmacology ; Pain/drug therapy ; Pain/etiology ; Analgesics/therapeutic use ; Analgesics/pharmacology ; Neoplasms/complications ; Neoplasms/drug therapy
    Chemical Substances Drugs, Chinese Herbal ; Analgesics
    Language English
    Publishing date 2024-01-26
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 193085-0
    ISSN 1793-6853 ; 0090-2942 ; 0192-415X
    ISSN (online) 1793-6853
    ISSN 0090-2942 ; 0192-415X
    DOI 10.1142/S0192415X24500058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Chinese national clinical practice guidelines on the prevention, diagnosis, and treatment of early gastric cancer.

    Li, Peng / Li, Ziyu / Linghu, Enqiang / Ji, Jiafu

    Chinese medical journal

    2024  Volume 137, Issue 8, Page(s) 887–908

    Abstract: Background: Gastric cancer is one of the most common malignant tumors in the digestive system in China. Few comprehensive practice guidelines for early gastric cancer in China are currently available. Therefore, we created the Chinese national clinical ... ...

    Abstract Background: Gastric cancer is one of the most common malignant tumors in the digestive system in China. Few comprehensive practice guidelines for early gastric cancer in China are currently available. Therefore, we created the Chinese national clinical practice guideline for the prevention, diagnosis, and treatment of early gastric cancer.
    Methods: This clinical practice guideline (CPG) was developed in accordance with the World Health Organization's recommended process and with the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) in assessing evidence quality. We used the Evidence to Decision framework to formulate clinical recommendations to minimize bias and increase transparency in the CPG development process. We used the Reporting Items for practice Guidelines in HealThcare (RIGHT) statement and the Appraisal of Guidelines for Research and Evaluation II (AGREE II) as reporting and conduct guidelines to ensure completeness and transparency of the CPG.
    Results: This CPG contains 40 recommendations regarding the prevention, screening, diagnosis, treatment, and follow-up of early gastric cancer based on available clinical studies and guidelines. We provide recommendations for the timing of Helicobacter pylori eradication, screening populations for early gastric cancer, indications for endoscopic resection and surgical gastrectomy, follow-up interval after treatment, and other recommendations.
    Conclusions: This CPG can lead to optimum care for patients and populations by providing up-to-date medical information. We intend this CPG for widespread adoption to increase the standard of prevention, screening, diagnosis, treatment, and follow-up of early gastric cancer; thereby, contributing to improving national health care and patient quality of life.
    MeSH term(s) Stomach Neoplasms/diagnosis ; Stomach Neoplasms/therapy ; Stomach Neoplasms/prevention & control ; Humans ; China ; Early Detection of Cancer ; Practice Guidelines as Topic ; Helicobacter Infections/diagnosis ; Helicobacter Infections/drug therapy
    Language English
    Publishing date 2024-03-21
    Publishing country China
    Document type Journal Article
    ZDB-ID 127089-8
    ISSN 2542-5641 ; 0366-6999 ; 1002-0187
    ISSN (online) 2542-5641
    ISSN 0366-6999 ; 1002-0187
    DOI 10.1097/CM9.0000000000003101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Effect of acupuncture at Shuitong and Shuijin points on sufentanil-induced cough in general anesthesia induction: a randomized controlled trial.

    Xu, Jiping / Ji, Jiafu / Hu, Lihua / Li, Peng / Su, Fan

    Zhongguo zhen jiu = Chinese acupuncture & moxibustion

    2024  Volume 44, Issue 1, Page(s) 62–66

    Abstract: Objectives: To observe the therapeutic effect of acupuncture at Shuitong and Shuijin points on preventing sufentanil-induced cough and its influence on hemodynamics in general anesthesia induction.: Methods: A total of 80 patients scheduled for ... ...

    Title translation 针刺水通、水金穴对全身麻醉诱导期舒芬太尼诱发呛咳的影响：随机对照试验.
    Abstract Objectives: To observe the therapeutic effect of acupuncture at Shuitong and Shuijin points on preventing sufentanil-induced cough and its influence on hemodynamics in general anesthesia induction.
    Methods: A total of 80 patients scheduled for elective surgery undergoing general anesthesia were randomly divided into an observation group (40 cases) and a control group (39 cases,1 case eliminated). In the control group, the routine anesthesia was performed,with intravenous injection of 1% sufentanil citrate 0.5 μg/kg, 1% propofol (total amount was calculated according to 2 mg/kg) and cisatracurium besilate 0.2 mg/kg. In the observation group, before routine anesthesia induction, acupuncture was applied to Shuitong and Shuijin points on the right and the needles were retained for 30 min. During anesthesia induction, the complications i.e. cough and chest wall stiffness were observed, and the systolic blood pressure (SBP), heart rate (HR) and pulse oxygen saturation (SpO
    Results: During anesthesia induction,the condition of mild, moderate and severe cough in the observation group was superior to that of the control group (
    Conclusions: Acupuncture at Shuitong and Shuijin points can effectively prevent from sufentanil-induced cough, reduce the severity of cough and stabilize the hemodynamic indicators.
    MeSH term(s) Humans ; Sufentanil/adverse effects ; Acupuncture Therapy ; Anesthesia, General/adverse effects ; Elective Surgical Procedures ; Cough/etiology ; Cough/therapy
    Chemical Substances Sufentanil (AFE2YW0IIZ)
    Language Chinese
    Publishing date 2024-01-08
    Publishing country China
    Document type Randomized Controlled Trial ; Journal Article
    ISSN 0255-2930
    ISSN 0255-2930
    DOI 10.13703/j.0255-2930.20230101-k0002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Standardization of cancer biobank in precision medicine era].

    Ji, Jiafu

    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences

    2016  Volume 45, Issue 4, Page(s) 331–334

    Abstract: Tumor specimens have a great role in basic and clinical translational researches on cancer, especially in the era of precision medicine. Thus the standardization of cancer biobank is of high importance. The establishment and maintenance of cancer biobank ...

    Abstract Tumor specimens have a great role in basic and clinical translational researches on cancer, especially in the era of precision medicine. Thus the standardization of cancer biobank is of high importance. The establishment and maintenance of cancer biobank require comprehensive quality management, so as to provide high quality service for basic and clinical researches. At present, sample-oriented collection and management, and clinical and pathological data annotation are the main focuses of biobank standardization in China.
    MeSH term(s) Biological Specimen Banks/standards ; Biomedical Research ; China ; Documentation/standards ; Humans ; Neoplasms ; Precision Medicine ; Specimen Handling/standards
    Language Chinese
    Publishing date 2016-10-18
    Publishing country China
    Document type Journal Article
    ISSN 1008-9292
    ISSN 1008-9292
    DOI 10.3785/j.issn.1008-9292.2016.07.01
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A commentary on

    Wei, Jingtao / Bu, Zhaode / Ji, Jiafu

    Medical review (Berlin, Germany)

    2022  Volume 1, Issue 2, Page(s) 126–128

    Language English
    Publishing date 2022-02-22
    Publishing country Germany
    Document type Journal Article
    ISSN 2749-9642
    ISSN (online) 2749-9642
    DOI 10.1515/mr-2021-0032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Comments on

    Chen, Jiahui / Bu, Zhaode / Ji, Jiafu

    Chinese journal of cancer research = Chung-kuo yen cheng yen chiu

    2022  Volume 34, Issue 5, Page(s) 453–455

    Language English
    Publishing date 2022-04-02
    Publishing country China
    Document type Journal Article
    ZDB-ID 1067584-x
    ISSN 1993-0631 ; 1000-9604
    ISSN (online) 1993-0631
    ISSN 1000-9604
    DOI 10.21147/j.issn.1000-9604.2022.05.04
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A commentary on

    Wei Jingtao / Bu Zhaode / Ji Jiafu

    Medical Review, Vol 1, Iss 2, Pp 126-

    “A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells” – tumor microenvironment: the Achilles heel of cancer

    2021  Volume 128

    Keywords Medicine ; R
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher De Gruyter
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Comments on Chinese guidelines for diagnosis and treatment of gastric cancer 2018 (English edition).

    Bu, Zhaode / Ji, Jiafu

    Chinese journal of cancer research = Chung-kuo yen cheng yen chiu

    2020  Volume 32, Issue 4, Page(s) 446–447

    Language English
    Publishing date 2020-09-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 1067584-x
    ISSN 1993-0631 ; 1000-9604
    ISSN (online) 1993-0631
    ISSN 1000-9604
    DOI 10.21147/j.issn.1000-9604.2020.04.02
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  9. Article ; Online: N6-methyladenosine (m6A) RNA modification in cancer stem cells.

    Ma, Zhonghua / Ji, Jiafu

    Stem cells (Dayton, Ohio)

    2020  

    Abstract: Cancer stem cells (CSCs), a unique subset of undifferentiated cells with stem cell-like properties, have emerged as driving forces in mediating tumor growth, metastasis, and therapeutic resistance. Recent advances have highlighted that N6-methyladenosine ...

    Abstract Cancer stem cells (CSCs), a unique subset of undifferentiated cells with stem cell-like properties, have emerged as driving forces in mediating tumor growth, metastasis, and therapeutic resistance. Recent advances have highlighted that N6-methyladenosine (m6A) RNA modification plays an important role in cancer biology and CSCs. Dynamic m6A decoration has been demonstrated to be involved in CSC generation and maintenance, governing cancer progression and therapeutic resistance. In this review, we provide the first overview of the current knowledge of m6A modification implicated in CSCs and their impact on CSC properties, tumor progression, and responses to treatment. Finally, we also highlight the potential of m6A machinery as novel targets for cancer therapeutics. The involvement of m6A modification in CSCs provides a new direction for exploring cancer pathogenesis and inspires the development of effective strategies to fully eliminate both cancer cells and CSCs.
    Language English
    Publishing date 2020-09-27
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1143556-2
    ISSN 1549-4918 ; 1066-5099
    ISSN (online) 1549-4918
    ISSN 1066-5099
    DOI 10.1002/stem.3279
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Associations of Annual Hospital and Surgeon Volume with Patient Outcomes After Gastrectomy: A Systematic Review and Meta-analysis.

    Ji, Jiafu / Shi, Leiyu / Ying, Xiangji / Lu, Xinpu / Shan, Fei

    Annals of surgical oncology

    2022  Volume 29, Issue 13, Page(s) 8276–8297

    Abstract: Background: Procedural volume is an important determinant of outcomes in cancer surgery. There is a lack of a comprehensive and updated assessment of hospital and surgeon volumes in relation to short- and long-term outcomes after gastrectomy for cancer.! ...

    Abstract Background: Procedural volume is an important determinant of outcomes in cancer surgery. There is a lack of a comprehensive and updated assessment of hospital and surgeon volumes in relation to short- and long-term outcomes after gastrectomy for cancer.
    Methods: The PubMed and Embase databases were searched on January 2021. We conducted meta-analyses and meta-regressions assuming a random effects model to assess the associations of procedural volumes with outcomes after gastrectomy. Effect sizes included hazard ratios (HRs), odds ratios (ORs), and standardized mean differences (SMDs). Heterogeneity was evaluated with the I
    Results: We identified 53 primary publications on the effect of hospital (n = 48) or surgeon (n = 11) volume on 11 gastrectomy outcomes. Patients operated on in high-volume centers had better overall survival (HR 0.82, 95% confidence interval [CI] 0.75-0.90), lower short-term mortality (OR 0.66, 95% CI 0.58-0.75), more adequate lymphadenectomy (OR 2.14, 95% CI 1.76-2.59), and shorter length of stay (SMD - 0.08, 95% CI - 0.12 to - 0.04). The meta-analysis showed no significant associations of hospital volume with surgical complications, R0 or negative margin resection, or disease-free survival (all p > 0.05). A higher surgeon volume was associated with lower 30-day mortality (OR 0.94, 95% CI 0.90-0.97).
    Conclusions: The current study suggested with high confidence that gastric cancer patients operated on in high-volume centers had better overall survival. Centralization of gastrectomy in high-volume centers might lead to an overall improvement in other outcomes, but more studies, especially on surgeon volume, are needed.
    MeSH term(s) Humans ; Gastrectomy ; Surgeons ; Stomach Neoplasms ; Hospitals ; Odds Ratio
    Language English
    Publishing date 2022-09-15
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-022-12515-y
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