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  1. Article ; Online: Response to: Factors associated with depression among Chinese residents in the later stages of the COVID-19 pandemic.

    Jiang, Y / Li, S M / Yang, Q P / Ji, Y Y / Zhu, H H

    QJM : monthly journal of the Association of Physicians

    2023  Volume 117, Issue 1, Page(s) 81

    MeSH term(s) Humans ; COVID-19/epidemiology ; Depression/epidemiology ; Pandemics ; China/epidemiology ; Anxiety
    Language English
    Publishing date 2023-08-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1199985-8
    ISSN 1460-2393 ; 0033-5622 ; 1460-2725
    ISSN (online) 1460-2393
    ISSN 0033-5622 ; 1460-2725
    DOI 10.1093/qjmed/hcad142
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Socio-demographic factors associated with depression maybe more important in the post-epidemic era.

    Jiang, Y / Li, S M / Yang, Q P / Ji, Y Y / Zhu, H H

    QJM : monthly journal of the Association of Physicians

    2023  Volume 116, Issue 9, Page(s) 818

    MeSH term(s) Humans ; Depression/epidemiology ; Socioeconomic Factors ; Anxiety ; Demography
    Language English
    Publishing date 2023-05-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1199985-8
    ISSN 1460-2393 ; 0033-5622 ; 1460-2725
    ISSN (online) 1460-2393
    ISSN 0033-5622 ; 1460-2725
    DOI 10.1093/qjmed/hcad118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: MiR-335-5p inhibits proliferation of Huh-7 liver cancer cells via targeting the Oct4/Akt pathway.

    Ji, Y-Y / Song, Y / Wang, A-N

    European review for medical and pharmacological sciences

    2021  Volume 25, Issue 4, Page(s) 1853–1860

    Abstract: Objective: The aim of this study was to detect the expression of micro ribonucleic acid (miR)-335-5p in the liver tissues of patients with liver cancer, and to explore its effect on liver cancer and mechanism using Huh7 human liver cancer cells.: ... ...

    Abstract Objective: The aim of this study was to detect the expression of micro ribonucleic acid (miR)-335-5p in the liver tissues of patients with liver cancer, and to explore its effect on liver cancer and mechanism using Huh7 human liver cancer cells.
    Patients and methods: Liver tissues were collected from patients with liver cancer. The expression of miR-335-5p in tissues was detected via quantitative reverse transcription-polymerase chain reaction (qRT-PCR). Subsequently, Huh7 cells were transfected with miR-335-5p in vitro. After overexpressing miR-335-5p, changes in the expression of octamer-binding transcription factor 4 (Oct4) gene were observed via qRT-PCR. Furthermore, the proliferation of Huh7 cells and the protein expressions of protein kinase B (Akt) and phosphorylated Akt (p-Akt) were detected using cell counting kit (CCK)-8 assay and Western blotting (WB), respectively.
    Results: Compared with Control group, the expression of miR-335-5p increased significantly in the liver tissues of liver cancer patients (p<0.01). In comparison with those in negative group, the messenger RNA (mRNA) expression of Oct4 and the proliferation rate of Huh7 cells were both significantly inhibited in miR-335-5p group (p<0.01, p<0.05). After overexpression of miR-335-5p, the protein expression level of p-Akt decreased remarkably (p<0.01).
    Conclusions: MiR-335-5p directly binds to the 3' untranslated region (3'UTR) of Oct4 mRNA to restrain the phosphorylation of Akt, thereby inhibiting Huh7 cell proliferation.
    MeSH term(s) Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; Cell Proliferation ; Female ; Humans ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Male ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Middle Aged ; Octamer Transcription Factor-3/genetics ; Octamer Transcription Factor-3/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism
    Chemical Substances MIRN335 microRNA, human ; MicroRNAs ; Octamer Transcription Factor-3 ; POU5F1 protein, human ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1)
    Language English
    Publishing date 2021-03-04
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_202102_25080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Predictive factors for enhanced community mental health vulnerability in this COVID-19 pandemic era.

    Li, S M / Guo, B B / Yang, Q P / Yin, J Y / Tian, L / Ji, Y Y / Jiang, Y / Zhu, H H

    QJM : monthly journal of the Association of Physicians

    2022  Volume 116, Issue 1, Page(s) 41–46

    Abstract: Objective: Explore the mental health status and its influencing factors of local community residents under the post-epidemic era of coronavirus disease 2019 (COVID-19) in China.: Methods: The basic information scale, self-rating depression scale and ... ...

    Abstract Objective: Explore the mental health status and its influencing factors of local community residents under the post-epidemic era of coronavirus disease 2019 (COVID-19) in China.
    Methods: The basic information scale, self-rating depression scale and self-rating anxiety scale were used to carry out an online questionnaire survey among community residents in Jiangsu Province, China, and the influencing factors of depression and anxiety were analyzed by multivariate logistic regression.
    Results: A total of 993 residents completed the mental health survey. It was found that the incidence of depressive and anxiety symptoms was 37.06% and 22.86%. Multivariate logistic regression analysis showed that women [odds ratio (OR) 95% confidence interval (95% CI) = 26.239 (14.743-46.698)], college degree and above [OR (95% CI) = 1.843 (1.085-3.130)] and ordinary residents [OR (95% CI) = 2.222 (1.441-3.425)] were risk factors for depressive symptoms, urban residents had lower risk [OR (95% CI) = 0.655 (0.394-0.829)]. Women [OR (95% CI) = 33.595 (15.812-71.381)] and ordinary residents [OR (95% CI) = 3.017 (1.602-5.680)] were risk factors for anxiety symptoms while the incidence was reduced in professional and technical personnel [OR (95% CI) = 0.271 (0.123-0.597)], workers [OR (95% CI) = 0.383 (0.168-0.876)], soldiers or policemen [OR (95% CI) = 0.200 (0.042-0.961)], married residents [OR (95% CI) = 0.463 (0.230-0.931)] and urban residents [OR (95% CI) = 0.531 (0.251-0.824)].
    Conclusion: The incidence of symptoms of depression and anxiety among residents was relatively high under the post-epidemic era of COVID-19, which could be affected by various factors.
    MeSH term(s) Humans ; Female ; COVID-19/epidemiology ; COVID-19/psychology ; SARS-CoV-2 ; Mental Health ; Pandemics ; Depression/epidemiology ; Depression/psychology ; Anxiety/etiology ; China/epidemiology
    Language English
    Publishing date 2022-08-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 1199985-8
    ISSN 1460-2393 ; 0033-5622 ; 1460-2725
    ISSN (online) 1460-2393
    ISSN 0033-5622 ; 1460-2725
    DOI 10.1093/qjmed/hcac191
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Value of fibrinogen to albumin ratio on predicting spontaneous recanalization of infarct-related artery in patients with acute ST-segment elevation myocardial infarction].

    Zhao, Y P / Ji, Y Y / Wang, F Y / Wang, S L / Lai, G K / Wang, T / Tang, J M

    Zhonghua xin xue guan bing za zhi

    2019  Volume 47, Issue 2, Page(s) 123–128

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Aged ; Albumins/analysis ; Coronary Angiography ; Fibrinogen/analysis ; Humans ; Infarction ; Male ; Middle Aged ; Predictive Value of Tests ; Recurrence ; Retrospective Studies ; ST Elevation Myocardial Infarction/diagnosis ; Uric Acid ; Vascular Patency
    Chemical Substances Albumins ; Uric Acid (268B43MJ25) ; Fibrinogen (9001-32-5)
    Language Chinese
    Publishing date 2019-02-28
    Publishing country China
    Document type Journal Article
    ZDB-ID 603425-1
    ISSN 0253-3758
    ISSN 0253-3758
    DOI 10.3760/cma.j.issn.0253-3758.2019.02.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Studies on immunohistochemical localization and immunotargeting of monoclonal antibody against human hepatocellular carcinoma].

    Ji, Y Y

    Zhonghua zhong liu za zhi [Chinese journal of oncology

    1993  Volume 15, Issue 5, Page(s) 335–338

    Abstract: Human hepatocellular carcinoma (HCC) cell line SMMC-7721 treated with human leucocytic alpha-interferon was used as immunogen to prepare monoclonal antibody against HCC. The anti-HCC monoclonal antibody (HAb23) was used to reacte with 51 cases of HCC, 38 ...

    Abstract Human hepatocellular carcinoma (HCC) cell line SMMC-7721 treated with human leucocytic alpha-interferon was used as immunogen to prepare monoclonal antibody against HCC. The anti-HCC monoclonal antibody (HAb23) was used to reacte with 51 cases of HCC, 38 cases of cirrhosis, 33 cases of hepatitis, 25 cases of other liver diseases, 36 cases of normal tissues including cryosections of fetus tissues and 231 cases of malignacies from various tissues by immunohistochemical staining. The results showed that 42 cases of HCC were positive, with a positive rate of 82.3%. Immuno-electron microscopic localization showed that HAb23 was localized mainly on the surface membrane and on the cytoplasmic membranous structures of tumor cells. The radioiodine conjugated HAb23 could target to the xenografts shown by ECT scanning. The ratios of tumor/liver and tumor/blood were 1.94-3.66 and 0.56-1.65, respectively. Five nm colloidal gold labeled HAb23 could also target to the xenografts. Our data suggest that the HAb23 is more specific to HCC and has a targeting ability to HCC in vivo.
    MeSH term(s) Animals ; Antibodies, Monoclonal/metabolism ; Carcinoma, Hepatocellular/immunology ; Carcinoma, Hepatocellular/metabolism ; Cell Membrane/ultrastructure ; Cytoplasm/ultrastructure ; Humans ; Immunohistochemistry ; Liver/metabolism ; Liver Neoplasms/immunology ; Liver Neoplasms/metabolism ; Mice ; Mice, Inbred BALB C ; Microscopy, Immunoelectron ; Neoplasm Transplantation
    Chemical Substances Antibodies, Monoclonal
    Language Chinese
    Publishing date 1993-09
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 603424-x
    ISSN 0253-3766
    ISSN 0253-3766
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Distribution of three proteinases in tumor cells of malignant histiocytosis].

    Ji, Y Y

    Zhonghua bing li xue za zhi = Chinese journal of pathology

    1990  Volume 19, Issue 3, Page(s) 185–187

    Abstract: Tumor tissues from 36 autopsy cases of malignant histiocytosis were collected for studying the distribution of lysozyme (LyS), alpha 1-antichymotrypsin (ACT) and alpha 1-antitrypsin (AT) by double peroxidase anti-peroxidase staining. The positive rates ... ...

    Abstract Tumor tissues from 36 autopsy cases of malignant histiocytosis were collected for studying the distribution of lysozyme (LyS), alpha 1-antichymotrypsin (ACT) and alpha 1-antitrypsin (AT) by double peroxidase anti-peroxidase staining. The positive rates of LyS, ACT and AT were 97.14%, 91.67% and 77.78% respectively. LyS was seen mainly in the well-differentiated histiocytes. No phagocytosis was found in these cells. ACT existed in some well-differentiated histiocytes in which phagocytosis was often seen. A few atypical histiocytes also showed positive reaction to ACT. AT-positive cells were mainly atypical histiocytes and atypical multinuclear-giant-histiocytes. This study not only confirms that the tumor cels of malignant histiocytosis originate from histiocytes, but also indicates that staining of LyS, ACT and AT is useful for classification and differential diagnosis of tumor cells in malignant histiocytosis.
    MeSH term(s) Histiocytic Sarcoma/enzymology ; Humans ; Immunohistochemistry ; Muramidase/metabolism ; alpha 1-Antichymotrypsin/metabolism ; alpha 1-Antitrypsin/metabolism
    Chemical Substances alpha 1-Antichymotrypsin ; alpha 1-Antitrypsin ; Muramidase (EC 3.2.1.17)
    Language Chinese
    Publishing date 1990-09
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 784533-9
    ISSN 0529-5807
    ISSN 0529-5807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [Localization of ricinus agglutinin receptors in tumor cells in malignant histiocytosis].

    Ji, Y Y

    Zhonghua yi xue za zhi

    1989  Volume 69, Issue 3, Page(s) 166–168

    MeSH term(s) Histiocytic Sarcoma/metabolism ; Histocytochemistry ; Humans ; Plant Proteins/analysis ; Receptors, Mitogen/analysis
    Chemical Substances Plant Proteins ; Receptors, Mitogen ; Ricinus communis lectin receptor
    Language Chinese
    Publishing date 1989-03
    Publishing country China
    Document type Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [Tuberculoma in the pleural cavity (report of 15 cases)].

    Ji, Y Y

    Zhonghua fang she xue za zhi Chinese journal of radiology

    1982  Volume 16, Issue 4, Page(s) 281–283

    MeSH term(s) Adult ; Female ; Humans ; Male ; Middle Aged ; Radiography ; Tuberculoma/diagnostic imaging ; Tuberculosis, Pleural/diagnostic imaging
    Language Chinese
    Publishing date 1982-11
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 604569-8
    ISSN 1005-1201
    ISSN 1005-1201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Flow cytometry analysis of the neutralization effect of anti-IL-8 McAbs on IL-8-activated human granulocytes.

    Ji, Y Y / Ye, G Q

    Shi yan sheng wu xue bao

    1995  Volume 28, Issue 3, Page(s) 257–261

    Abstract: Two hybridoma clones, I8-S2 and I 8-63, secreting anti- IL-8 antibodies were constructed from fusion of immunized spleen cells of BALB/c mice with either Sp 2/0 or 653 myeloma cells. They recognized different epitopes on IL-8 molecule. IL-8 could ... ...

    Abstract Two hybridoma clones, I8-S2 and I 8-63, secreting anti- IL-8 antibodies were constructed from fusion of immunized spleen cells of BALB/c mice with either Sp 2/0 or 653 myeloma cells. They recognized different epitopes on IL-8 molecule. IL-8 could activate human granulocytes and induce the elevation of [Ca2+]i. Through flow cytometry analysis the two clones displayed different neutralizing effects on the cell activation function of IL-8. The neutralizing effect of clone I8-S2 was apparently higher than that of clone I8-63. It is suggested that the cell activation function of IL-8 is restricted to a certain epitope of IL-8 molecule.
    MeSH term(s) Animals ; Antibodies, Monoclonal/biosynthesis ; Antibodies, Monoclonal/pharmacology ; Biological Transport, Active ; Calcium/metabolism ; Flow Cytometry ; Granulocytes/metabolism ; Humans ; Hybridomas/secretion ; Interleukin-8/immunology ; Mice ; Mice, Inbred BALB C
    Chemical Substances Antibodies, Monoclonal ; Interleukin-8 ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 1995-09
    Publishing country China
    Document type Journal Article
    ZDB-ID 955679-5
    ISSN 0001-5334 ; 0371-4853
    ISSN 0001-5334 ; 0371-4853
    Database MEDical Literature Analysis and Retrieval System OnLINE

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