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Article ; Online: Clinical application of nursing risk management in nursing management of surgical patients.

Guo, Jian L

2024

Language	English
Publishing date	2024-03-04
Publishing country	Italy
Document type	Journal Article
ZDB-ID	3067899-7
ISSN	2724-5438
ISSN (online)	2724-5438
DOI	10.23736/S2724-5691.23.10177-8
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Article ; Online: The Internet of Things Term Feature Extraction Method and Its Application in English-Chinese Translation.

Jian, Lili

Computational intelligence and neuroscience

2022 Volume 2022, Page(s) 2134627

Abstract: From the emergence of the concept of the Internet of Things to today, China has always been very concerned about the development of the Internet of Things technology. The research and application of Internet of Things technology has become an important ... ...

Abstract	From the emergence of the concept of the Internet of Things to today, China has always been very concerned about the development of the Internet of Things technology. The research and application of Internet of Things technology has become an important measure for the country to promote supply-side reform. The Internet of Things technology is the core innovation content of the country and an important measure to realize the smart city. This paper analyzes the cutting-edge research results in the field of Internet of Things abroad. This paper focuses on the application of IoT technology in English terminology research. This paper specifically analyzes the feature extraction methods of Internet of Things terms and studies the application content of Internet of Things technology in English-Chinese translation. We specifically conduct translation research on the content in "The Internet of Things: Enabling Technologies, Platforms, and Use Cases," focusing on the translation of scientific and technological terms. As a kind of technical English terminology, IoT English terminology has the characteristics of strong professionalism and rigorous semantics. This article specifically translates the original part of the practice report and classifies the terms that appear in it, including IoT English terms for which canonical translations have been made and IoT English terms that do not have standardized translations. The research will further carry out the investigation and analysis work. The research is to identify the terms that have standardized translation, especially the detailed research of the terms of the industry field. This paper selects standard translations and summarizes the translation methods of terms from three aspects: abbreviations, compound words, and semi-technical words. The research results provide guidance for terminology translation. This article translates terms that do not yet have a canonical translation. Based on terminology characteristics and existing terminology translation methods, this paper proposes a variety of translation methods such as literal translation, decomposing and combining, and non-translation. The study described in detail with examples. The research results of this paper are expected to provide some reference for translators engaged in the translation of scientific and technological documents.
MeSH term(s)	China ; Industry ; Internet ; Internet of Things ; Technology
Language	English
Publishing date	2022-04-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2388208-6
ISSN	1687-5273 ; 1687-5273
ISSN (online)	1687-5273
ISSN	1687-5273
DOI	10.1155/2022/2134627
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Article: Unexpected diffuse lung lesions in a patient with pulmonary alveolar proteinosis: A case report.

Jian, Li / Zhao, Qi-Quan

World journal of clinical cases

2023 Volume 11, Issue 20, Page(s) 4932–4936

Abstract: Background: Pulmonary alveolar proteinosis (PAP) often presents nonspecifically and can be easily confused with: (1) Idiopathic interstitial lung fibrosis; (2) alveolar carcinoma; (3) pulmonary tuberculosis; and (4) other lung diseases such as viral ... ...

Abstract	Background: Pulmonary alveolar proteinosis (PAP) often presents nonspecifically and can be easily confused with: (1) Idiopathic interstitial lung fibrosis; (2) alveolar carcinoma; (3) pulmonary tuberculosis; and (4) other lung diseases such as viral pneumonia, mycoplasma pneumonia, and chlamydial pneumonia. Case summary: Diagnosis: In this case, a patient was diagnosed with PAP through transbronchial cryobiopsy (TBCB) and quantitative metagenomic next-generation sequencing, which confirmed the impairment of surfactant turnover as the underlying cause of PAP. Interventions: High-volume total lung lavage was performed for this patient. Outcomes: The patient's clinical condition had improved significantly by the 6-month follow-up, with a 92% finger oxygen saturation. A repeat chest computed tomography scan revealed scattered patchy ground-glass shadows in both lungs, which was consistent with alveolar protein deposition but with a lower density than in the radiograph from October 23, 2022. Conclusion: TBCB has unique advantages in diagnosing atypical alveolar protein deposition, particularly for enabling the early detection of PAP. This information can help patients take preventive measures to prevent or halt PAP development by avoiding dusty environments and seeking treatment with total lung lavage and inhaled granulocyte macrophage colony-stimulating factor.
Language	English
Publishing date	2023-08-11
Publishing country	United States
Document type	Case Reports
ISSN	2307-8960
ISSN	2307-8960
DOI	10.12998/wjcc.v11.i20.4932
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Article ; Online: Inhibition of Ceramide Kinase Is Effective against Cisplatin-Resistant Ovarian Cancer Cells by Regulating Ceramide and C1P Levels.

Zou, Jing / Jian, Long

Gynecologic and obstetric investigation

2023 Volume 88, Issue 1, Page(s) 61–70

Abstract: Objective: Chemoresistance in ovarian cancer results in treatment failure, yet underlying mechanisms that regulate chemoresistance remain largely unclear. There is emerging evidence relating ovarian cancer drug resistance with bioactive sphingolipids ... ...

Abstract	Objective: Chemoresistance in ovarian cancer results in treatment failure, yet underlying mechanisms that regulate chemoresistance remain largely unclear. There is emerging evidence relating ovarian cancer drug resistance with bioactive sphingolipids and regulation of sphingolipid metabolism. This work investigated the expression and function of ceramide kinase (CerK), a lipid kinase that regulates central bioactive sphingolipids, in ovarian cancer, as well as the therapeutic potential of targeting CERK. Design: The levels of ceramide, ceramide 1-phosphate (C1P), and Cerk in ovarian cancer and normal counterparts were measured. Functions of Cerk in ovarian cancer were examined. Materials, setting, methods: Immunohistochemistry, ELISA, and mass spectrometry methods were used to measure the level of ceramides, C1P, and CerK in primary tissues. Proliferation and apoptosis assays were performed in ovarian cancer cells after CERK depletion, CERK overexpression, and NVP-231 treatment in the absence or presence of cisplatin. Results: Compared to normal ovarian cells, CerK and its mediating bioactive sphingolipids ceramide and C1P were decreased in ovarian cancer tissues. Interestingly, cisplatin-resistant ovarian cancer cells displayed increased CerK, decreased ceramide, and increased C1P, and furthermore, that CerK level was closely associated with ceramide and C1P levels in ovarian cancer cells. Functional analysis demonstrated that CerK overexpression was sufficient to promote growth and confer chemoresistance in ovarian cancer cells. CerK inhibition via both genetic and pharmacological approaches suppressed growth and induced apoptosis in cisplatin-resistant cells, and furthermore, this significantly augmented cisplatin's efficacy. Limitations: The functional analysis of C1P was performed on in vitro ovarian cancer cells. In vivo studies were needed to further confirm the effects of CERK inhibition. Conclusions: Our work is the first to show the critical role of CerK as the underlying mechanism of ovarian cancer chemoresistance, through regulating ceramide and C1P.
MeSH term(s)	Humans ; Female ; Cisplatin/pharmacology ; Ovarian Neoplasms/drug therapy ; Ceramides/metabolism ; Ceramides/pharmacology ; Sphingolipids
Chemical Substances	ceramide 1-phosphate ; Cisplatin (Q20Q21Q62J) ; ceramide kinase (EC 2.7.1.138) ; Ceramides ; Sphingolipids
Language	English
Publishing date	2023-01-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	800003-7
ISSN	1423-002X ; 0378-7346
ISSN (online)	1423-002X
ISSN	0378-7346
DOI	10.1159/000528869
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Zs.A 688: Show issues

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Article: [Primary mucinous cystadenocarcinoma of the breast with hormone receptor expression: report of a case].

Luo, S Y / Zhou, M L / Jian, L / Wang, D Z

Zhonghua bing li xue za zhi = Chinese journal of pathology

2023 Volume 52, Issue 10, Page(s) 1055–1057

MeSH term(s)	Humans ; Breast/pathology ; Cystadenocarcinoma/pathology ; Cystadenocarcinoma, Mucinous/pathology ; Female
Language	Chinese
Publishing date	2023-10-05
Publishing country	China
Document type	Case Reports ; Journal Article
ZDB-ID	784533-9
ISSN	0529-5807
ISSN	0529-5807
DOI	10.3760/cma.j.cn112151-20230215-00130
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Zs.MO 360: Show issues

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Article ; Online: Accurate estimation of concrete consumption in tunnel lining using terrestrial laser scanning.

Jian, Liao / Qiu, Wenge / Cheng, Yunjian

Scientific reports

2024 Volume 14, Issue 1, Page(s) 2705

Abstract: Accurate estimation of concrete (including shotcrete) consumption plays a crucial role in tunnel construction. A novel method has been introduced to accurately estimate concrete consumption with terrestrial laser scanning (TLS). The estimation needs to ... ...

Abstract	Accurate estimation of concrete (including shotcrete) consumption plays a crucial role in tunnel construction. A novel method has been introduced to accurately estimate concrete consumption with terrestrial laser scanning (TLS). The estimation needs to capture TLS data of tunnel surfaces at different stages of construction. Unrolling point clouds, a novel two-stage algorithm consisting of noise removal and hole filling has been used to generate resampled points. Furthermore, resampled points from two scans (before and after lining construction) ultimately generate an innovative computation model composed of multiple hexahedral elements, which is used for calculating volumes. The proposed technique was applied to the Tiantaishan highway tunnel and Da Fang Shan high-speed railway tunnel. The calculation relative error of the rebound rate is 0.19%, and the average relative error in predicting the demand for secondary lining concrete is 0.15%. Compared with 3D Delaunay with curve fitting, the proposed technique offers a more straightforward operation and higher accuracy. Considering factors such as tunnel geometry, support design, and concrete properties, a computational model will provide valuable insights into optimizing resource allocation and reducing material waste during construction.
Language	English
Publishing date	2024-02-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-51132-x
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Article ; Online: Stochastic dynamical analysis for the complex infectious disease model driven by multisource noises.

Jian, Liqiong / Bai, Xinyu / Ma, Shaojuan

PloS one

2024 Volume 19, Issue 1, Page(s) e0296183

Abstract: This paper mainly studies the dynamical behavior of the infectious disease model affected by white noise and Lévy noise. First, a stochastic model of infectious disease with secondary vaccination affected by noises is established. Besides, the existence ... ...

Abstract	This paper mainly studies the dynamical behavior of the infectious disease model affected by white noise and Lévy noise. First, a stochastic model of infectious disease with secondary vaccination affected by noises is established. Besides, the existence and uniqueness of the global positive solution for the stochastic model are proved based on stochastic differential equations and Lyapunov function, then the asymptotic behavior of the disease-free equilibrium point is studied. Moreover, the sufficient conditions for the extinction of the disease are obtained and the analysis showed that different noise intensity could affect the extinction of infectious disease on different degree. Finally, the theoretical results are verified by numerical simulation and some suggestions have been put forward on how to prevent the spread of diseases are presented.
MeSH term(s)	Humans ; Stochastic Processes ; Communicable Diseases ; Computer Simulation ; Immunization, Secondary
Language	English
Publishing date	2024-01-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0296183
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Article ; Online: Morphological Changes of Collagen Fibers in Myocardium of Rats under Different Exercise Loads Based on Three-Dimensional Simulation Technique.

Jian, Liu

Journal of medical systems

2019 Volume 43, Issue 6, Page(s) 154

Abstract: In order to improve the visual analysis ability of the morphological changes of rat liulimyocardial collagen fibers under different exercise loads, a method of extracting the morphological changes of collagen fibers in rat myocardium under different ... ...

Abstract	In order to improve the visual analysis ability of the morphological changes of rat liulimyocardial collagen fibers under different exercise loads, a method of extracting the morphological changes of collagen fibers in rat myocardium under different exercise loads based on three-dimensional simulation technique is proposed. The three-dimensional morphological characteristics of the collagen fibers in the original rat myocardium are made by CT scanning technique. Like information collection, a gradient decomposition method is used to filter the three-dimensional morphological features of rat myocardial collagen fibers. The edge contour features of the three-dimensional morphological features of rat myocardial collagen fibers under different motion loads are extracted. The threshold segmentation method is used to carry out the rat myocardial glue under different exercise loads. The segmentation of the regional pixel feature block of the three-dimensional morphological features of the original fiber is segmented into a block vector with high resolution, and the regional reconstruction of the three-dimensional morphological features of the rat myocardial collagen fibers under different motion loads is carried out to realize the high resolution identification and classification of the 3D morphological features of the rat myocardial collagen fibers. The simulation results show that the three-dimensional simulation of the morphological changes of rat myocardial collagen fibers under different exercise loads is better, and the accuracy of feature extraction is higher.
MeSH term(s)	Animals ; Collagen/physiology ; Image Processing, Computer-Assisted/methods ; Imaging, Three-Dimensional/methods ; Myocardium/metabolism ; Physical Conditioning, Animal/physiology ; Rats ; Tomography, X-Ray Computed
Chemical Substances	Collagen (9007-34-5)
Language	English
Publishing date	2019-04-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	423488-1
ISSN	1573-689X ; 0148-5598
ISSN (online)	1573-689X
ISSN	0148-5598
DOI	10.1007/s10916-019-1290-9
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Zs.A 1426: Show issues

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Article ; Online: NGDE: A Niching-Based Gradient-Directed Evolution Algorithm for Nonconvex Optimization.

Yu, Qi / Liang, Xijun / Li, Mengzhen / Jian, Ling

IEEE transactions on neural networks and learning systems

2024 Volume PP

Abstract: Nonconvex optimization issues are prevalent in machine learning and data science. While gradient-based optimization algorithms can rapidly converge and are dimension-independent, they may, unfortunately, fall into local optimal solutions or saddle points. ...

Abstract	Nonconvex optimization issues are prevalent in machine learning and data science. While gradient-based optimization algorithms can rapidly converge and are dimension-independent, they may, unfortunately, fall into local optimal solutions or saddle points. In contrast, evolutionary algorithms (EAs) gradually adapt the population of solutions to explore global optimal solutions. However, this approach requires substantial computational resources to perform numerous fitness function evaluations, which poses challenges for high-dimensional optimization in particular. This study introduces a novel nonconvex optimization algorithm, the niching-based gradient-directed evolution (NGDE) algorithm, designed specifically for high-dimensional nonconvex optimization. The NGDE algorithm generates potential solutions and divides them into multiple niches to explore distinct areas within the feasible region. Subsequently, each individual creates candidate offspring using the gradient-directed mutation operator we designed. The convergence properties of the NGDE algorithm are investigated in two scenarios: accessing the full gradient and approximating the gradient with mini-batch samples. The experimental studies demonstrate the superior performance of the NGDE algorithm in minimizing multimodal optimization functions. Additionally, when applied to train the neural networks of LeNet-5, NGDE shows significantly improved classification accuracy, especially in smaller training sizes.
Language	English
Publishing date	2024-04-15
Publishing country	United States
Document type	Journal Article
ISSN	2162-2388
ISSN (online)	2162-2388
DOI	10.1109/TNNLS.2024.3378805
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Article ; Online: LncRNA ZFPM2-AS1 drives the progression of nasopharyngeal carcinoma via modulating the downstream miR-3612/DTL signaling.

Chang, Xiaojing / Jian, Lei

Anti-cancer drugs

2022 Volume 33, Issue 6, Page(s) 523–533

Abstract: LncRNA ZFPM2-AS1 has been illuminated to function as a carcinogenic driver in various human cancers. Whereas, the role of ZFPM2-AS1 in nasopharyngeal carcinoma (NPC) remains puzzled. To further understand NPC pathogenesis, we investigated the regulatory ... ...

Abstract	LncRNA ZFPM2-AS1 has been illuminated to function as a carcinogenic driver in various human cancers. Whereas, the role of ZFPM2-AS1 in nasopharyngeal carcinoma (NPC) remains puzzled. To further understand NPC pathogenesis, we investigated the regulatory effects of ZFPM2-AS1 in NPC. Expression analysis for ZFPM2-AS1, miR-3612 and denticleless E3 ubiquitin protein ligase homolog (DTL) mRNA was carried out using real-time quantitative PCR. For the expression analysis of DTL protein, a western blot assay was applied. Cell proliferation was ascertained using the cell counting kit-8 assay and colony formation assay. Cell apoptosis was estimated based on the expression levels of BCL2-Associated X and B-cell lymphoma-2 using western blot assay. To verify the role of ZFPM2-AS1, a Xenograft model was prepared in vivo. The underlying binding between miR-3612 and ZFPM2-AS1 or DTL was validated through dual-luciferase-reporter assay or protein immunoprecipitation assay. ZFPM2-AS1 showed upregulated expression in NPC samples and cells. Meanwhile, ZFPM2-AS1 was mainly located in the cytoplasm. Knockdown of ZFPM2-AS1 restrained NPC cell proliferation and induced apoptosis, as well as suppressed tumorigenesis in animal models. ZFPM2-AS1 targeted miR-3612 whose expression was decreased in NPC samples and cells. Repression of miR-3612 aggravated NPC cell development and largely reversed the functional role of ZFPM2-AS1 silencing on NPC cell growth. MiR-3612 directly interacted with DTL, and DTL expression was upregulated in NPC. Downregulation of DTL blocked NPC cell growth, while miR-3612 inhibition partly abrogated the effects of DTL knockdown. ZFPM2-AS1 knockdown considerably restrained NPC development via targeting the miR-3612/DTL signaling. The study provided new insights to understand NPC pathogenesis.
MeSH term(s)	Animals ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; DNA-Binding Proteins/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Nasopharyngeal Carcinoma/genetics ; Nasopharyngeal Neoplasms/genetics ; Nuclear Proteins/metabolism ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Transcription Factors/metabolism
Chemical Substances	DNA-Binding Proteins ; DTL protein, human ; MicroRNAs ; Nuclear Proteins ; RNA, Long Noncoding ; Transcription Factors ; ZFPM2 protein, human
Language	English
Publishing date	2022-03-08
Publishing country	England
Document type	Journal Article
ZDB-ID	1065301-6
ISSN	1473-5741 ; 0959-4973
ISSN (online)	1473-5741
ISSN	0959-4973
DOI	10.1097/CAD.0000000000001282
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