LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 66

Search options

  1. Article ; Online: Fast and Accurate Position Determination of Multimodal Couplings of Steel Rolling Machinery and Equipment Combined with Multimedia Optimized Particle Filters

    Jian Tan

    Advances in Multimedia, Vol

    2021  Volume 2021

    Abstract: During the overhaul and maintenance of the transmission system of the modern rolling mill, a very common problem is the positioning of the motor and the reducer or speed increaser. The operation of the equipment and the service life of the equipment will ...

    Abstract During the overhaul and maintenance of the transmission system of the modern rolling mill, a very common problem is the positioning of the motor and the reducer or speed increaser. The operation of the equipment and the service life of the equipment will be significantly affected by the accuracy of the multimodal coupling position determination. Therefore, precise positioning and rapid positioning must be achieved. This article intends to analyze how this type of equipment achieves rapid and accurate positioning and what factors will affect the location determination process.
    Keywords Electronic computers. Computer science ; QA75.5-76.95
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  2. Article ; Online: Multimodal and multi-omics-based deep learning model for screening of optic neuropathy

    Ye-ting Lin / Qiong Zhou / Jian Tan / Yulin Tao

    Heliyon, Vol 9, Iss 12, Pp e22244- (2023)

    2023  

    Abstract: Purpose: To examine the use of multimodal data and multi-omics strategies for optic nerve disease screening. Methods: This was a single-center retrospective study. A deep learning model was created from fundus photography and infrared reflectance (IR) ... ...

    Abstract Purpose: To examine the use of multimodal data and multi-omics strategies for optic nerve disease screening. Methods: This was a single-center retrospective study. A deep learning model was created from fundus photography and infrared reflectance (IR) images of patients with diabetic optic neuropathy, glaucomatous optic neuropathy, and optic neuritis. Patients who were seen at the Ophthalmology Department of First Affiliated Hospital of Nanchang University in Jiangxi Province from November 2019 to April 2023 were included in this study. The data were analyzed in single and multimodal modes following the traditional omics, Resnet101, and fusion models. The accuracy and area-under-the-curve (AUC) of each model were compared. Results: A total of 312 images fundus and infrared fundus photographs were collected from 156 patients. When multi-modal data was used, the accuracy of the traditional omics mode, Resnet101, and fusion models with the training set were 0.97, 0.98, and 0.99, respectively. The accuracy of the same models with the test sets were 0.72, 0.87, and 0.88, respectively. We compared single- and multi-mode states by applying the data to the different groups in the learning model. In the traditional omics model, the macro-average AUCs of the features extracted from fundus photography, IR images, and multimodal data were 0.94, 0.90, and 0.96, respectively. When the same data were processed in the Resnet101 model, the scores were 0.97 equally. However, when multimodal data was utilized, the macro-average AUCs in the traditional omics, Resnet101, and fusion modesl were 0.96, 0.97, and 0.99, respectively. Conclusion: The deep learning model based on multimodal data and multi-omics strategies can improve the accuracy of screening and diagnosing diabetic optic neuropathy, glaucomatous optic neuropathy, and optic neuritis.
    Keywords Multimodal1 ; Multi-omics 2 ; Deep Learning3 ; Diabetic optic neuropathy4 ; Glaucomatous optic neuropathy5 ; Optic neuritis6 ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  3. Article ; Online: Identification for Abutment Stress by Drilling Cuttings

    Jian Tan / Yunliang Tan / Zihui Wang / Yubao Zhang

    Applied Sciences, Vol 11, Iss 9467, p

    2021  Volume 9467

    Abstract: The concentration of abutment pressure acting on coal seams induced by mining is a key factor to trigger rock burst. Understanding of abutment pressure or stress concentration is fundamental in preventing and controlling rock burst. The influence on ... ...

    Abstract The concentration of abutment pressure acting on coal seams induced by mining is a key factor to trigger rock burst. Understanding of abutment pressure or stress concentration is fundamental in preventing and controlling rock burst. The influence on abutment pressure fluctuation caused by the inhomogeneity of coal seams needs to be considered, but it is difficult to obtain by the present usual ways such as acoustic transmission, electromagnetic wave transmission, etc. In this article, the relationship between the amount of cuttings drilled in a coal seam and stress level was analyzed by considering the effect of drilling cutting expansion, and the drilling cutting test was carried out in Xinglongzhuang Coal Mine, Shandong Energy Ltd. It is found that the amount of cuttings drilled is positively related to the degree of stress concentration in both the plastic fracture zone and elastic zone. The amount of drilling cuttings is closely related to the roof weighting. In addition, the irregular fluctuation of drilling cuttings is an approximate map of distribution of stress concentration because of the non-uniformity of cracks and other defects in the coal seam. In order to meet the need of rock burst prevention by accurate pressure relief in high-stress zones, enough boreholes are needed.
    Keywords abutment stress ; drilling cutting ; roof weighting ; pressure relief ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 670
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  4. Article ; Online: Summer marine heatwaves in the South China Sea

    Hong-Jian Tan / Rong-Shuo Cai / Ren-Guang Wu

    Advances in Climate Change Research, Vol 13, Iss 3, Pp 323-

    Trend, variability and possible causes

    2022  Volume 332

    Abstract: Marine heatwaves (MHWs) have been frequently observed worldwide, causing devastating impacts on marine organisms and ecosystems, but the trend of MHWs is still unclear in the South China Sea (SCS). Here, the long-term trend and inter-annual variability ... ...

    Abstract Marine heatwaves (MHWs) have been frequently observed worldwide, causing devastating impacts on marine organisms and ecosystems, but the trend of MHWs is still unclear in the South China Sea (SCS). Here, the long-term trend and inter-annual variability of the summer SCS MHW events are investigated based on the high-resolution daily satellite data. The results revealed remarkable increases in the duration, intensity, coverage, and severity during 1982–2019, indicating that the SCS MHW events have become more frequent, intense, extensive, and serious. The probability ratio of SCS MHW events is four times during the 2010s of that during the 1980s. The increasing trend can be largely attributed to the long-term increase in the mean SCS temperature. The inter-annual variability of the SCS MHWs is linked closely to the El Niño and Southern Oscillation, with more/less MHW events occurring during the following summer after the El Niño/La Niña events. A diagnosis of synoptic-scale heat budget suggests that the extreme SCS warming can be explained by the combined effects of positive surface heat flux largely due to the enhanced shortwave radiation and convergence of oceanic advection in association with an anomalous upper-ocean anticyclone. The effect of surface heat flux seems to be predominant over the large spatial coverage, whereas oceanic heat transport is also important in some specific regions. The large-scale anticyclonic circulation anomalies over the northwestern Pacific accompanying the westward-extending western Pacific subtropical high during the El Niño decay summers play an essential role in the building-up and persistence of the extreme warming, which has important implications for the prediction of the SCS MHWs.
    Keywords Marine heatwaves ; South China Sea ; El niño ; Northwestern pacific anticyclone ; Meteorology. Climatology ; QC851-999 ; Social sciences (General) ; H1-99
    Subject code 551
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher KeAi Communications Co., Ltd.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  5. Article ; Online: Causes of 2022 summer marine heatwave in the East China Seas

    Hong-Jian Tan / Rong-Shuo Cai / Dong-Ping Bai / Karim Hilmi / Kareem Tonbol

    Advances in Climate Change Research, Vol 14, Iss 5, Pp 633-

    2023  Volume 641

    Abstract: Recent occurrences of marine heatwaves (MHWs) in coastal China seas have caused serious impacts on marine ecosystem services and socio-economics. Nevertheless, the underlying physical process, including local drivers and remote associations, remains ... ...

    Abstract Recent occurrences of marine heatwaves (MHWs) in coastal China seas have caused serious impacts on marine ecosystem services and socio-economics. Nevertheless, the underlying physical process, including local drivers and remote associations, remains poorly understood, thereby hindering accurate predictability. In this study, we reported an extreme MHW event in the East China Seas (ECSs, including the Bohai, Yellow, and East China Sea), lasting for 75 d with a maximum intensity of 1.96 °C relative to 1982–2011 during the summer 2022. This ECSs MHW event was triggered by a combination of anomalous atmospheric and oceanic conditions, including enhanced insolation, weakened surface wind speed, suppressed latent heat loss from ocean, a shallower mixed layer, and upper ocean current anomaly. Mixed-layer temperature budget diagnosis suggested that changes in the ECSs temperature were dominated by the surface net heat flux, largely due to strong shortwave radiation flux, during the development and decay of the MHW event. Oceanic advection also created favorable conditions for the maintenance of the MHW. These physical drivers were further regulated by the westward expanded and intensified western Pacific subtropical high (WPSH), potentially linked to the negative phase of Indian Ocean Dipole (IOD). Despite the three years (2020–2022) consecutive La Niña events, the ECSs summer MHWs appeared to be more closely linked to negative IOD events, with a lagging period of 1–3 mon. The seasonal precursor signals of the negative IOD have the potential to affect local physical drivers of ECSs MHWs through regulating the strength and position of WPSH, thus serving as a promising predictor for the ECSs MHWs. The future likelihood and intensity of the ECSs MHWs are projected to increase substantially in the coming decades, largely due to broad-scale warming attributed to anthropogenic climate change. Consequently, there is an urgent need to develop MHW forecasting and early warning systems, and robust approaches to address climate ...
    Keywords Marine heatwaves ; East China Seas ; Indian ocean dipole ; Western Pacific subtropical high ; Meteorology. Climatology ; QC851-999 ; Social sciences (General) ; H1-99
    Subject code 551
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher KeAi Communications Co., Ltd.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  6. Article ; Online: Retrospective study of the influence of hypothyroidism on liver function before radioiodine therapy in China

    Wei Zheng / Yanhui Ji / Zhaowei Meng / Cailan Wu / Jian Tan / Renfei Wang

    BMJ Open, Vol 12, Iss

    a comparison analysis based on patients with differentiated thyroid cancer

    2022  Volume 1

    Keywords Medicine ; R
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  7. Article ; Online: Expert systems in oil palm precision agriculture

    Xiao Jian Tan / Wai Loon Cheor / Kwok Shien Yeo / Wai Zhe Leow

    Journal of King Saud University: Computer and Information Sciences, Vol 34, Iss 4, Pp 1569-

    A decade systematic review

    2022  Volume 1594

    Abstract: Oil palm (Elaeis guineensis Jacq.) is of the most profitable and widespread commercial high tree crops in the tropical world, typically in Southeastern Asia. The present study aims to provide a brief but broad overview of different applications of expert ...

    Abstract Oil palm (Elaeis guineensis Jacq.) is of the most profitable and widespread commercial high tree crops in the tropical world, typically in Southeastern Asia. The present study aims to provide a brief but broad overview of different applications of expert systems (ESs) in oil palm precision agriculture (PA), focusing on the three main generic categories: crop, water, and soil management. This study is meant to review research articles from the past decade: 2011–2020. Based on the search strategy alongside the inclusion criteria, 108 articles were included for synthesis activity. The findings of the study reveal patterns, networks, relationships, and trends in the application of ESs in oil palm PA in the past decade. The broad insight obtained from the synthesis activity was used to identify the possible roads ahead in oil palm PA. The findings of this study could be useful and beneficial to the research community and stakeholders in identifying the progress and trends of ESs in oil palm PA in the past decade, help to gain a holistic view on research gaps, potential markets, relevant advantages, the roads ahead, and contributing to further systematic research (deepen or broaden) in this topic.
    Keywords Oil palm ; Elaeis guineensis Jacq ; Expert system ; Precision agriculture ; Systematic review ; Systematic bibliographic survey ; Electronic computers. Computer science ; QA75.5-76.95
    Subject code 571
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  8. Article ; Online: VIRTUAL SCENE CONSTRUCTION OF LARGE-SCALE CULTURAL HERITAGE

    Jian Tan / Shenghua Wang

    Computer Science & Information Technology, Vol 6, Iss 1, Pp 267-

    A FRAMEWORK INITIATED FROM THE CASE STUDY OF THE GRAND CANAL OF CHINA

    2016  Volume 286

    Abstract: Virtual reality technology has been applied to the protection of cultural heritage for about 20 years. However, methods or systems of cultural heritage reported in previous studies are still unable to represent large-scale cultural heritage sites such as ...

    Abstract Virtual reality technology has been applied to the protection of cultural heritage for about 20 years. However, methods or systems of cultural heritage reported in previous studies are still unable to represent large-scale cultural heritage sites such as the Beijing-Hangzhou Grand Canal, the Struve Geodetic Arc and the boundaries of the Roman Empire. We aimed at constructing a large-scale cultural-heritage 3-D model with the focus on better management and organization of the scene. Starting from the case study of the Beijing-Hangzhou Grand Canal, we first explore various remote sensing data suitable for large-scale cultural heritage modeling, and then adopt a 3-D geographic global information system for large-scale 3-D scene organization and management. The entire 3-D virtual scene reconstruction process can be divided into four steps. The first one is the remote-sensing data preparation, where TM, SPOT5 and other remote sensing data were selected according to the characteristics of the cultural heritage of the Grand Canal and further subjected to data filtering and geometric correction. In the second step, the 3-D terrain modeling was carried out based on 3-D earth model segmentation and tile hierarchy system, where we fused and split remote sensing image and sampling spatial information for 3-D terrain model. The third step involves the modeling of local heritage with sophisticated modeling techniques sufficient to build a heritage 3-D model and to integrate terrain model with local scene through aerial orthophotos. Finally, in the fourth step the virtual scene integration is performed in a 3-D spherical system, where we designed a tree nodes system to assembly and manage multi-level and multi-type models of the Grand Canal. After these four steps are completed, the large-scale cultural heritage scene in 3-D spherical information system can be achieved. Here, we address main challenges in virtual scene reconstruction of large-scale cultural heritage. This study can be valuable for regional and national cultural heritage protection as well as for Chinese government as a reference to infrastructural research, and finally for stimulation of other large-scale cultural heritage research around the world both in 3-D modeling and virtual scene organization.
    Keywords Virtual scene construction ; large-scale cultural heritage ; the Grand Canal ; Electronic computers. Computer science ; QA75.5-76.95 ; Instruments and machines ; QA71-90 ; Mathematics ; QA1-939 ; Science ; Q
    Subject code 004
    Language English
    Publishing date 2016-01-01T00:00:00Z
    Publisher Academy & Industry Research Collaboration Center (AIRCC)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  9. Article ; Online: MiR-199a-5p–HIF-1α-STAT3 Positive Feedback Loop Contributes to the Progression of Non-Small Cell Lung Cancer

    Xingping Yang / Yuzhen Zheng / Jian Tan / Renjiang Tian / Piao Shen / Weijie Cai / Hongying Liao

    Frontiers in Cell and Developmental Biology, Vol

    2021  Volume 8

    Abstract: Background: Non-small cell lung cancer (NSCLC) is the most common malignancy worldwide. MiR-199a-5p has been reported to play important roles in multiple tumors, inclusive of NSCLC. However, little is definitively known pertaining to its explicit ... ...

    Abstract Background: Non-small cell lung cancer (NSCLC) is the most common malignancy worldwide. MiR-199a-5p has been reported to play important roles in multiple tumors, inclusive of NSCLC. However, little is definitively known pertaining to its explicit mechanism of action in NSCLC.Methods: The expressions of miR-199a-5p and hypoxia-inducible factor-1α (HIF-1α) mRNA were quantified employing qRT-PCR. H1299 and A549 cells were transiently transfected with miR-199a-5p mimics or inhibitors. Then, CCK-8 assays, flow cytometry analysis, and Transwell assay were performed for detecting cell proliferation, cell cycle, apoptosis, migration, and invasion of NSCLC cells, respectively. HIF-1α, signal transducer and activator of transcription 3 (STAT3), and p-STAT3 expressions were detected via Western blotting. Bioinformatic analysis and dual-luciferase assay were performed to investigate the interactions among miR-199a-5p, HIF-1α, and STAT3. Xenograft models were established with nude mice for further analyzing the bevacizumab resistance of NSCLC cells.Results: MiR-199a-5p expression was markedly attenuated in NSCLC tissues and cell lines. Overexpression of miR-199a-5p repressed the proliferation, migration, and invasion but induced the apoptosis of NSCLC cells. HIF-1α was identified as a direct target of miR-199a-5p. There was a positive feedback loop among miR-199a-5p, HIF-1α, and STAT3. Co-transfection of HIF-1α or STAT3 overexpression plasmids counteracted the effects of miR-199a-5p. In vivo experiments indicated that the feedback loop was in association with the bevacizumab resistance of NSCLC cells.Conclusion: MiR-199a-5p blocked the progression of NSCLC and sensitized NSCLC cells to bevacizumab by suppressing HIF-1α and STAT3, while the HIF-1α/STAT3 axis suppressed the expression of miR-199a-5p, which forms a positive feedback loop to promote the sustaining progression of NSCLC.
    Keywords MiR-199a-5p ; HIF-1α ; stat3 ; non-small cell lung cancer ; bevacizumab ; Biology (General) ; QH301-705.5
    Subject code 610
    Language English
    Publishing date 2021-02-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  10. Article ; Online: Modeling early changes associated with cartilage trauma using human-cell-laden hydrogel cartilage models

    Chunrong He / Karen L. Clark / Jian Tan / Hecheng Zhou / Rocky S. Tuan / Hang Lin / Song Wu / Peter G. Alexander

    Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-

    2022  Volume 13

    Abstract: Abstract Background Traumatic impacts to the articular joint surface are known to lead to cartilage degeneration, as in post-traumatic osteoarthritis (PTOA). Limited progress in the development of disease-modifying OA drugs (DMOADs) may be due to ... ...

    Abstract Abstract Background Traumatic impacts to the articular joint surface are known to lead to cartilage degeneration, as in post-traumatic osteoarthritis (PTOA). Limited progress in the development of disease-modifying OA drugs (DMOADs) may be due to insufficient mechanistic understanding of human disease onset/progression and insufficient in vitro models for disease and therapeutic modeling. In this study, biomimetic hydrogels laden with adult human mesenchymal stromal cells (MSC) are used to examine the effects of traumatic impacts as a model of PTOA. We hypothesize that MSC-based, engineered cartilage models will respond to traumatic impacts in a manner congruent with early PTOA pathogenesis observed in animal models. Methods Engineered cartilage constructs were fabricated by encapsulating adult human bone marrow-derived mesenchymal stem cells in a photocross-linkable, biomimetic hydrogel of 15% methacrylated gelatin and promoting chondrogenic differentiation for 28 days in a defined medium and TGF-β3. Constructs were subjected to traumatic impacts with different strains or 10 ng/ml IL-1β, as a common comparative method of modeling OA. Cell viability and metabolism, elastic modulus, gene expression, matrix protein production and activation of catabolic enzymes were assessed. Results Cell viability staining showed that traumatic impacts of 30% strain caused an appropriate level of cell death in engineered cartilage constructs. Gene expression and histo/immunohistochemical analyses revealed an acute decrease in anabolic activities, such as COL2 and ACAN expression, and a rapid increase in catabolic enzyme expression, e.g., MMP13, and inflammatory modulators, e.g., COX2. Safranin O staining and GAG assays together revealed a transient decrease in matrix production 24 h after trauma that recovered within 7 days. The decrease in elastic modulus of engineered cartilage constructs was coincident with GAG loss and mediated by the encapsulated cells. The acute and transient changes observed after traumatic impacts ...
    Keywords Human mesenchymal stem cells ; 3D cartilage models ; Methacrylated gelatin chondrogenesis ; Traumatic impact loading ; Post-traumatic osteoarthritis (PTOA) ; Medicine (General) ; R5-920 ; Biochemistry ; QD415-436
    Subject code 616
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

To top