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  1. Article ; Online: SOPA‐GA‐CNN

    Jia‐Cheng Huang / Guo‐Qiang Zeng / Guang‐Gang Geng / Jian Weng / Kang‐Di Lu

    IET Cyber-systems and Robotics, Vol 5, Iss 1, Pp n/a-n/a (2023)

    Synchronous optimisation of parameters and architectures by genetic algorithms with convolutional neural network blocks for securing Industrial Internet‐of‐Things

    2023  

    Abstract: Abstract In recent years, deep learning has been applied to a variety of scenarios in Industrial Internet of Things (IIoT), including enhancing the security of IIoT. However, the existing deep learning methods utilised in IIoT security are manually ... ...

    Abstract Abstract In recent years, deep learning has been applied to a variety of scenarios in Industrial Internet of Things (IIoT), including enhancing the security of IIoT. However, the existing deep learning methods utilised in IIoT security are manually designed by heavily relying on the experience of the designers. The authors have made the first contribution concerning the joint optimisation of neural architecture search and hyper‐parameters optimisation for securing IIoT. A novel automated deep learning method called synchronous optimisation of parameters and architectures by GA with CNN blocks (SOPA‐GA‐CNN) is proposed to synchronously optimise the hyperparameters and block‐based architectures in convolutional neural networks (CNNs) by genetic algorithms (GA) for the intrusion detection issue of IIoT. An efficient hybrid encoding strategy and the corresponding GA‐based evolutionary operations are designed to characterise and evolve both the hyperparameters, including batch size, learning rate, weight optimiser and weight regularisation, and the architectures, such as the block‐based network topology and the parameters of each CNN block. The experimental results on five intrusion detection datasets in IIoT, including secure water treatment, water distribution, Gas Pipeline, Botnet in Internet of Things and Power System Attack Dataset, have demonstrated the superiority of the proposed SOPA‐GA‐CNN to the state‐of‐the‐art manually designed models and neuron‐evolutionary methods in terms of accuracy, precision, recall, F1‐score, and the number of parameters of the deep learning models.
    Keywords cyber‐systems ; deep learning ; deep neural network ; Internet of things ; swarm intelligence ; Cybernetics ; Q300-390 ; Electronic computers. Computer science ; QA75.5-76.95
    Subject code 006
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Scalable Revocable Identity-Based Signature Scheme with Signing Key Exposure Resistance from Lattices

    Congge Xie / Jian Weng / Jinming Wen

    Security and Communication Networks, Vol

    2020  Volume 2020

    Abstract: In 2014, a new security definition of a revocable identity-based signature (RIBS) with signing key exposure resistance was introduced. Based on this new definition, many scalable RIBS schemes with signing key exposure resistance were proposed. However, ... ...

    Abstract In 2014, a new security definition of a revocable identity-based signature (RIBS) with signing key exposure resistance was introduced. Based on this new definition, many scalable RIBS schemes with signing key exposure resistance were proposed. However, the security of these schemes is based on traditional complexity assumption, which is not secure against attacks in the quantum era. Lattice-based cryptography has many attractive features, and it is believed to be secure against quantum computing attacks. We reviewed existing lattice-based RIBS schemes and found that all these schemes are vulnerable to signing key exposure. Hence, in this paper, we propose the first lattice-based RIBS scheme with signing key exposure resistance by using the left-right lattices and delegation technology. In addition, we employ a complete subtree revocation method to ensure our construction meeting scalability. Finally, we prove that our RIBS scheme is selective-ID existentially unforgeable against chosen message attacks (EUF-sID-CMA) under the standard short integer solutions (SIS) assumption in the random oracle model.
    Keywords Technology (General) ; T1-995 ; Science (General) ; Q1-390
    Subject code 005
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Hindawi-Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Enhanced peroxidase-like activity of MoS2/graphene oxide hybrid with light irradiation for glucose detection

    Peng, Jian / Jian Weng

    Biosensors & bioelectronics. 2017 Mar. 15, v. 89

    2017  

    Abstract: Construction of novel enzyme-free mimetic is very important in improving the sensitivity of biosensor. Here, an intrinsic peroxidase-like activity of MoS2 and graphene oxide (MoS2/GO) hybrid is demonstrated and the hybrid is also used to detect glucose ... ...

    Abstract Construction of novel enzyme-free mimetic is very important in improving the sensitivity of biosensor. Here, an intrinsic peroxidase-like activity of MoS2 and graphene oxide (MoS2/GO) hybrid is demonstrated and the hybrid is also used to detect glucose with high sensitivity. Firstly, the peroxidase-like activity of hydrid is compared with that of two components alone, the mixture of two components and horseradish peroxidase. The results show that the hydrid has highest catalytic activity and the Michaelis constant of this hybrid is 4.35 times lower and the maximal reaction velocity is 3.34 times higher than those of horseradish peroxidase, respectively. Electrochemical technologies are used to investigate the enhancing mechanism. The results show that the excellently catalytic performance could be attributed to the fast electron transfer on the surface of MoS2/GO and the synergistic interaction of two components. Secondly, the effect of visible light and near-infrared light on the peroxidase-like activity of hybrid is also investigated. The results show that the limit of detection for H2O2 can be reduced from 10nM to 2.5nM with visible light. Thirdly, the hybrid is further used to detect glucose in serum with and without light. The results show that the hybrid has high selectivity and sensitivity for glucose detection in serum and the limit of detection for glucose is reduced from 0.83μM to 65nM with visible light. Therefore, the hybrid may have a potential application in glucose detection in serum with high sensitivity and selectivity.
    Keywords biosensors ; blood glucose ; blood serum ; catalytic activity ; detection limit ; electrochemistry ; electron transfer ; glucose ; graphene oxide ; hydrogen peroxide ; irradiation ; peroxidase ; synergism
    Language English
    Dates of publication 2017-0315
    Size p. 652-658.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 1011023-9
    ISSN 1873-4235 ; 0956-5663
    ISSN (online) 1873-4235
    ISSN 0956-5663
    DOI 10.1016/j.bios.2015.12.034
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: The strategies of perioperative management in orthopedic department during the pandemic of COVID-19

    Hui Zeng / Guoqing Li / Jian Weng / Ao Xiong / Chang Xu / Yifei Yang / Deli Wang

    Journal of Orthopaedic Surgery and Research, Vol 15, Iss 1, Pp 1-

    2020  Volume 9

    Abstract: Abstract Background Coronavirus disease 2019 (COVID-19) has broken out and spread rapidly nationwide at the beginning of 2020, which has brought huge impacts to people and work. The current situation of prevention and control is severe and urges guidance ...

    Abstract Abstract Background Coronavirus disease 2019 (COVID-19) has broken out and spread rapidly nationwide at the beginning of 2020, which has brought huge impacts to people and work. The current situation of prevention and control is severe and urges guidance for clinicians, especially for medical systems. In the hope of providing a reference and recommendation for the prevention and control of the COVID-19, we carried out research to improve the quality of patient care and prevention during this epidemic. Methods All of the staff were trained rapidly to master personal protection in our department. We reviewed the patients’ discharged records who underwent surgery in our department during January 1 to March 1, 2019, and January 1 to March 1, 2020. The management of the surgery patients and flow charts were described and analyzed. Post-operation outcomes of the patients include duration, complications, surgical site infection (SSI), system infection, re-operation, and mortality. Both chi-squared test and Student’s t test were performed to determine the relationship between the two periods in terms of post-operation outcomes. Results Descriptive statistics analysis revealed that demographic of the patients between the two periods is similar. We had benefited from the strict flowcharts, smart robot, and protection equipment during the perioperative managements for orthopedic patients. With the help of the strict flow charts and smart equipment, post-operation outcomes of the patients revealed that the rates of the complications and re-operation had been reduced significantly (p < 0.05), while duration of operation, SSI, and system infection had no significant difference between two periods (p > 0.05). No patient and staff caught COVID-19 infection or mortality during the epidemic. Conclusions Our study indicated that medical quality and efficiency were affected little with the help of strategies described above during the epidemic, which could be a reference tool for medical staff in routine clinical practice for admission of patients around the world. What is more, the provided strategies, which may evolve over time, could be used as empirical guidance and reference for orthopedic peers to get through the pandemic and ensure the normal operation of the hospital.
    Keywords Coronavirus disease 2019 (COVID-19) ; Orthopedic surgery ; Perioperative management ; Flow chart ; RD701-811 ; Diseases of the musculoskeletal system ; RC925-935 ; covid19
    Subject code 650 ; 610
    Language English
    Publishing date 2020-10-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Strongly Unforgeable Certificateless Signature Resisting Attacks from Malicious-But-Passive KGC

    Wenjie Yang / Jian Weng / Weiqi Luo / Anjia Yang

    Security and Communication Networks, Vol

    2017  Volume 2017

    Abstract: In digital signature, strong unforgeability requires that an attacker cannot forge a new signature on any previously signed/new messages, which is attractive in both theory and practice. Recently, a strongly unforgeable certificateless signature (CLS) ... ...

    Abstract In digital signature, strong unforgeability requires that an attacker cannot forge a new signature on any previously signed/new messages, which is attractive in both theory and practice. Recently, a strongly unforgeable certificateless signature (CLS) scheme without random oracles was presented. In this paper, we firstly show that the scheme fails to achieve strong unforgeability by forging a new signature on a previously signed message under its adversarial model. Then, we point out that the scheme is also vulnerable to the malicious-but-passive key generation center (MKGC) attacks. Finally, we propose an improved strongly unforgeable CLS scheme in the standard model. The improved scheme not only meets the requirement of strong unforgeability but also withstands the MKGC attacks. To the best of our knowledge, we are the first to prove a CLS scheme to be strongly unforgeable against the MKGC attacks without using random oracles.
    Keywords Technology (General) ; T1-995 ; Science (General) ; Q1-390
    Language English
    Publishing date 2017-01-01T00:00:00Z
    Publisher Hindawi-Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: The Effects of Long-term Abacus Training on Topological Properties of Brain Functional Networks

    Jian Weng / Ye Xie / Chunjie Wang / Feiyan Chen

    Scientific Reports, Vol 7, Iss 1, Pp 1-

    2017  Volume 8

    Abstract: Abstract Previous studies in the field of abacus-based mental calculation (AMC) training have shown that this training has the potential to enhance a wide variety of cognitive abilities. It can also generate specific changes in brain structure and ... ...

    Abstract Abstract Previous studies in the field of abacus-based mental calculation (AMC) training have shown that this training has the potential to enhance a wide variety of cognitive abilities. It can also generate specific changes in brain structure and function. However, there is lack of studies investigating the impact of AMC training on the characteristics of brain networks. In this study, utilizing graph-based network analysis, we compared topological properties of brain functional networks between an AMC group and a matched control group. Relative to the control group, the AMC group exhibited higher nodal degrees in bilateral calcarine sulcus and increased local efficiency in bilateral superior occipital gyrus and right cuneus. The AMC group also showed higher nodal local efficiency in right fusiform gyrus, which was associated with better math ability. However, no relationship was significant in the control group. These findings provide evidence that long-term AMC training may improve information processing efficiency in visual-spatial related regions, which extend our understanding of training plasticity at the brain network level.
    Keywords Medicine ; R ; Science ; Q
    Subject code 796
    Language English
    Publishing date 2017-08-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: An injectable liposome-anchored teriparatide incorporated gallic acid-grafted gelatin hydrogel for osteoarthritis treatment

    Guoqing Li / Su Liu / Yixiao Chen / Jin Zhao / Huihui Xu / Jian Weng / Fei Yu / Ao Xiong / Anjaneyulu Udduttula / Deli Wang / Peng Liu / Yingqi Chen / Hui Zeng

    Nature Communications, Vol 14, Iss 1, Pp 1-

    2023  Volume 18

    Abstract: Abstract Intra-articular injection of therapeutics is an effective strategy for treating osteoarthritis (OA), but it is hindered by rapid drug diffusion, thereby necessitating high-frequency injections. Hence, the development of a biofunctional hydrogel ... ...

    Abstract Abstract Intra-articular injection of therapeutics is an effective strategy for treating osteoarthritis (OA), but it is hindered by rapid drug diffusion, thereby necessitating high-frequency injections. Hence, the development of a biofunctional hydrogel for improved delivery is required. In this study, we introduce a liposome-anchored teriparatide (PTH (1–34)) incorporated into a gallic acid-grafted gelatin injectable hydrogel (GLP hydrogel). We show that the GLP hydrogel can form in situ and without affecting knee motion after intra-articular injection in mice. We demonstrate controlled, sustained release of PTH (1–34) from the GLP hydrogel. We find that the GLP hydrogel promotes ATDC5 cell proliferation and protects the IL-1β-induced ATDC5 cells from further OA progression by regulating the PI3K/AKT signaling pathway. Further, we show that intra-articular injection of hydrogels into an OA-induced mouse model promotes glycosaminoglycans synthesis and protects the cartilage from degradation, supporting the potential of this biomaterial for OA treatment.
    Keywords Science ; Q
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: SOX12 Promotes Stem Cell-Like Phenotypes and Osteosarcoma Tumor Growth by Upregulating JAGGED1

    Weifei Zhang / Fei Yu / Jian Weng / Yien Zheng / Jianjing Lin / Tiantian Qi / Yihao Wei / Deli Wang / Hui Zeng

    Stem Cells International, Vol

    2021  Volume 2021

    Abstract: SOX12 plays a role in promoting the growth of some tumors; however, its role in osteosarcoma remains unclear. From gene expression omnibus (GEO) and tumor alterations relevant for genomics-driven therapy (TARGET) databases, Kaplan–Meier analyses were ... ...

    Abstract SOX12 plays a role in promoting the growth of some tumors; however, its role in osteosarcoma remains unclear. From gene expression omnibus (GEO) and tumor alterations relevant for genomics-driven therapy (TARGET) databases, Kaplan–Meier analyses were conducted to establish relationships between SOX12 expression and osteosarcoma survival and recurrence in osteosarcoma patients. We also performed in vitro and in vivo assays to determine SOX12 function in osteosarcoma etiology. SOX12 expression was increased in osteosarcoma; high SOX12 expression levels were related to a poor prognosis and a high disease recurrence in patients. Moreover, SOX12 expression in osteosarcoma cell lines was increased, similar to osteosarcoma cancer stem cells. We also observed that SOX12 knockdown inhibited the spheroidization and expression of stemness markers in osteosarcoma cells and tumor formation in nude mice. In addition, SOX12 knockdown inhibited JAGGED1 and HES1 expression. Similarly, JAGGED1 knockdown also inhibited the formation of osteosarcoma cancer stem cells into pellets and reduced the expression of stemness markers and tumor formation capabilities in nude mice. Finally, during SOX12 knockdown, JAGGED1 overexpression rescued osteosarcoma cells from spheroidizing. SOX12 promotes stem cell-like phenotypes and osteosarcoma tumor growth by upregulating JAGGED1.
    Keywords Internal medicine ; RC31-1245
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: [Enrichment Factors, Health Risk, and Source Identification of Heavy Metals in Agricultural Soils in Semi-arid Region of Hainan Island].

    Yang, Jian-Zhou / Gong, Jing-Jing / Wang, Zhen-Liang / Gao, Jian-Weng / Yang, Jian-Kun / Hu, Shu-Qi / Tang, Shi-Xin

    Huan jing ke xue= Huanjing kexue

    2022  Volume 43, Issue 10, Page(s) 4590–4600

    Abstract: To understand the enrichment factors and pollution levels of heavy metals in agricultural soils in the semi-arid region of Hainan island, 1818 surface soil samples were collected in Gancheng Town and analyzed for their heavy metal contents and ... ...

    Abstract To understand the enrichment factors and pollution levels of heavy metals in agricultural soils in the semi-arid region of Hainan island, 1818 surface soil samples were collected in Gancheng Town and analyzed for their heavy metal contents and physicochemical composition. Correlation analysis was used to determine the heavy metal enrichment factors. The geo-accumulation index (
    MeSH term(s) Cadmium/analysis ; Carcinogens/analysis ; Child ; China ; Environmental Monitoring/methods ; Humans ; Lead/analysis ; Mercury/analysis ; Metals, Heavy/analysis ; Risk Assessment ; Soil/chemistry ; Soil Pollutants/analysis
    Chemical Substances Carcinogens ; Metals, Heavy ; Soil ; Soil Pollutants ; Cadmium (00BH33GNGH) ; Lead (2P299V784P) ; Mercury (FXS1BY2PGL)
    Language Chinese
    Publishing date 2022-10-12
    Publishing country China
    Document type Journal Article
    ISSN 0250-3301
    ISSN 0250-3301
    DOI 10.13227/j.hjkx.202201015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Survey on research of mini-drones security

    Wei LIU,Bing-wen FENG, Jian WENG

    网络与信息安全学报, Vol 2, Iss 3, Pp 39-

    2016  Volume 45

    Abstract: With the decreasing of the manufacturing cost and the development of technology, mini-drones are spreading from military and high-end commercial areas to civilian and consumer areas, and they have attracted great interests in recent years. On the one ... ...

    Abstract With the decreasing of the manufacturing cost and the development of technology, mini-drones are spreading from military and high-end commercial areas to civilian and consumer areas, and they have attracted great interests in recent years. On the one hand, mini-drones bring convenient, and on the other hand, they face with serious security problems. The research status of mini-drones, including the security threats of mini drones, the security attacks from mini drones, the authentication and traceability of mini drones, etc were introduced and analyzed. Finally, the future development of security research in mini-drones was also prospected.
    Keywords mini-drone ; information security ; security threat ; privacy invasion ; certification ; Electronic computers. Computer science ; QA75.5-76.95
    Language English
    Publishing date 2016-03-01T00:00:00Z
    Publisher POSTS&TELECOM PRESS Co., LTD
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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