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  1. Article: Visible Light-Driven Micromotors in Fuel-Free Environment with Promoted Ion Tolerance.

    Jiang, Huaide / He, Xiaoli / Yang, Ming / Hu, Chengzhi

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 12

    Abstract: Light-driven electrophoretic micromotors have gained significant attention recently for applications in drug delivery, targeted therapy, biosensing, and environmental remediation. Micromotors that possess good biocompatibility and the ability to adapt to ...

    Abstract Light-driven electrophoretic micromotors have gained significant attention recently for applications in drug delivery, targeted therapy, biosensing, and environmental remediation. Micromotors that possess good biocompatibility and the ability to adapt to complex external environments are particularly attractive. In this study, we have fabricated visible light-driven micromotors that could swim in an environment with relatively high salinity. To achieve this, we first tuned the energy bandgap of rutile TiO
    Language English
    Publishing date 2023-06-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13121827
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Physical Surface Modification of Carbon-Nanotube/Polydimethylsiloxane Composite Electrodes for High-Sensitivity DNA Detection.

    Moon, Junga / Jiang, Huaide / Lee, Eun-Cheol

    Nanomaterials (Basel, Switzerland)

    2021  Volume 11, Issue 10

    Abstract: The chemical modification of electrode surfaces has attracted significant attention for lowering the limit of detection or for improving the recognition of biomolecules; however, the chemical processes are complex, dangerous, and difficult to control. ... ...

    Abstract The chemical modification of electrode surfaces has attracted significant attention for lowering the limit of detection or for improving the recognition of biomolecules; however, the chemical processes are complex, dangerous, and difficult to control. Therefore, instead of the chemical process, we physically modified the surface of carbon-nanotube/polydimethylsiloxane composite electrodes by dip coating them with functionalized multi-walled carbon nanotubes (F-MWCNTs). These electrodes are used as working electrodes in electrochemistry, where they act as a recognition layer for sequence-specific DNA sensing through π-π interactions. The F-MWCNT-modified electrodes showed a limit of detection of 19.9 fM, which was 1250 times lower than that of pristine carbon/polydimethylsiloxane electrodes in a previous study, with a broad linear range of 1-1000 pM. The physically modified electrode was very stable during the electrode regeneration process after DNA detection. Our method paves the way for utilizing physical modification to significantly lower the limit of detection of a biosensor system as an alternative to chemical processes.
    Language English
    Publishing date 2021-10-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano11102661
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Polydopamine-Modified 2D Iron (II) Immobilized MnPS

    Xie, Hanhan / Yang, Ming / He, Xiaoli / Zhan, Zhen / Jiang, Huaide / Ma, Yanmei / Hu, Chengzhi

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2023  Volume 11, Issue 7, Page(s) e2306494

    Abstract: Manganese phosphosulphide ( ... ...

    Abstract Manganese phosphosulphide (MnPS
    MeSH term(s) Phototherapy ; Iron ; Photothermal Therapy ; Cell Line, Tumor ; Polyethylene Glycols/chemistry ; Multimodal Imaging/methods ; Neoplasms/diagnostic imaging ; Neoplasms/therapy ; Indoles ; Polymers
    Chemical Substances polydopamine ; Iron (E1UOL152H7) ; Polyethylene Glycols (3WJQ0SDW1A) ; Indoles ; Polymers
    Language English
    Publishing date 2023-12-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202306494
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  4. Article ; Online: Highly selective, reusable electrochemical impedimetric DNA sensors based on carbon nanotube/polymer composite electrode without surface modification.

    Jiang, Huaide / Lee, Eun-Cheol

    Biosensors & bioelectronics

    2018  Volume 118, Page(s) 16–22

    Abstract: We fabricated a composite of multi-walled carbon nanotube and polydimethylsiloxane and utilized it as an electrode for DNA sensing using electrochemical impedance spectroscopy. Without any surface modification or probe immobilization, often necessary for ...

    Abstract We fabricated a composite of multi-walled carbon nanotube and polydimethylsiloxane and utilized it as an electrode for DNA sensing using electrochemical impedance spectroscopy. Without any surface modification or probe immobilization, often necessary for other electrodes, this electrode also acts as a recognition layer for DNA via π-π interactions between the multi-walled carbon nanotube and DNA. This electrode is easily reusable via a simple cleansing process, because there are no covalently bonded adsorbates on the electrode. Compared to previous DNA detection based on differential pulse voltammetry using a similar electrode, the measurement time was reduced from 1 h to less than 30 min, and the limit of detection (25 pM) was reduced by a factor of more than five. In addition, our system can detect the single-base mismatch between the target and probe. Our results indicate that electrochemical impedance spectroscopy is promising for utilizing the multi-walled carbon nanotube and polydimethylsiloxane electrode as a DNA sensor.
    MeSH term(s) Biosensing Techniques/instrumentation ; Carbon/chemistry ; DNA/analysis ; Electrochemistry ; Electrodes ; Nanotubes, Carbon ; Polymers/chemistry
    Chemical Substances Nanotubes, Carbon ; Polymers ; Carbon (7440-44-0) ; DNA (9007-49-2)
    Language English
    Publishing date 2018-07-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1011023-9
    ISSN 1873-4235 ; 0956-5663
    ISSN (online) 1873-4235
    ISSN 0956-5663
    DOI 10.1016/j.bios.2018.07.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2275: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Enhanced and Robust Directional Propulsion of Light-Activated Janus Micromotors by Magnetic Spinning and the Magnus Effect

    Li, Jianjie / He, Xiaoli / Jiang, Huaide / Xing, Yi / Fu, Bi / Hu, Chengzhi

    ACS applied materials & interfaces. 2022 Aug. 02, v. 14, no. 31

    2022  

    Abstract: Advances in the versatile design and synthesis of nanomaterials have imparted diverse functionalities to Janus micromotors as autonomous vehicles. However, a significant challenge remains in maneuvering Janus micromotors by following desired trajectories ...

    Abstract Advances in the versatile design and synthesis of nanomaterials have imparted diverse functionalities to Janus micromotors as autonomous vehicles. However, a significant challenge remains in maneuvering Janus micromotors by following desired trajectories for on-demand motility and intelligent control due to the inherent rotational Brownian motion. Here, we present the enhanced and robust directional propulsion of light-activated Fe₃O₄@TiO₂/Pt Janus micromotors by magnetic spinning and the Magnus effect. Once exposed to a low-intensity rotating magnetic field, the micromotors become physically actuated, and their rotational Brownian diffusion is quenched by the magnetic rotation. Photocatalytic propulsion can be triggered by unidirectional irradiation based on a self-electrophoretic mechanism. Thus, a transverse Magnus force can be generated due to the rotational motion and ballistic motion (photocatalytic propulsion) of the micromotors. Both the self-electrophoretic propulsion and the Magnus force are periodically changed due to the magnetic rotation, which results in an overall directed motion moving toward a trajectory with a deflection angle from the direction of incident light with enhanced speed, maneuverability, and steering robustness. Our study illustrates the admirable directional motion capabilities of light-driven Janus micromotors based on magnetic spinning and the Magnus effect, which unfolds a new paradigm for addressing the limitations of directionality control in the current asymmetric micromotors.
    Keywords irradiation ; magnetic fields ; maneuverability ; photocatalysis
    Language English
    Dates of publication 2022-0802
    Size p. 36027-36037.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1944-8252
    DOI 10.1021/acsami.2c08464
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: Highly selective, reusable electrochemical impedimetric DNA sensors based on carbon nanotube/polymer composite electrode without surface modification

    Jiang, Huaide / Eun-Cheol Lee

    Biosensors & bioelectronics. 2018 Oct. 30, v. 118

    2018  

    Abstract: We fabricated a composite of multi-walled carbon nanotube and polydimethylsiloxane and utilized it as an electrode for DNA sensing using electrochemical impedance spectroscopy. Without any surface modification or probe immobilization, often necessary for ...

    Abstract We fabricated a composite of multi-walled carbon nanotube and polydimethylsiloxane and utilized it as an electrode for DNA sensing using electrochemical impedance spectroscopy. Without any surface modification or probe immobilization, often necessary for other electrodes, this electrode also acts as a recognition layer for DNA via π-π interactions between the multi-walled carbon nanotube and DNA. This electrode is easily reusable via a simple cleansing process, because there are no covalently bonded adsorbates on the electrode. Compared to previous DNA detection based on differential pulse voltammetry using a similar electrode, the measurement time was reduced from 1 h to less than 30 min, and the limit of detection (25 pM) was reduced by a factor of more than five. In addition, our system can detect the single-base mismatch between the target and probe. Our results indicate that electrochemical impedance spectroscopy is promising for utilizing the multi-walled carbon nanotube and polydimethylsiloxane electrode as a DNA sensor.
    Keywords biosensors ; carbon nanotubes ; chemical bonding ; detection limit ; dielectric spectroscopy ; DNA ; electrochemistry ; electrodes ; polydimethylsiloxane
    Language English
    Dates of publication 2018-1030
    Size p. 16-22.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 1011023-9
    ISSN 1873-4235 ; 0956-5663
    ISSN (online) 1873-4235
    ISSN 0956-5663
    DOI 10.1016/j.bios.2018.07.037
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2275: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Enhanced and Robust Directional Propulsion of Light-Activated Janus Micromotors by Magnetic Spinning and the Magnus Effect.

    Li, Jianjie / He, Xiaoli / Jiang, Huaide / Xing, Yi / Fu, Bi / Hu, Chengzhi

    ACS applied materials & interfaces

    2022  Volume 14, Issue 31, Page(s) 36027–36037

    Abstract: Advances in the versatile design and synthesis of nanomaterials have imparted diverse functionalities to Janus micromotors as autonomous vehicles. However, a significant challenge remains in maneuvering Janus micromotors by following desired trajectories ...

    Abstract Advances in the versatile design and synthesis of nanomaterials have imparted diverse functionalities to Janus micromotors as autonomous vehicles. However, a significant challenge remains in maneuvering Janus micromotors by following desired trajectories for on-demand motility and intelligent control due to the inherent rotational Brownian motion. Here, we present the enhanced and robust directional propulsion of light-activated Fe
    Language English
    Publishing date 2022-08-02
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.2c08464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Evaluation of the Inhibitory Effects of Six Natural Product Extracts against Babesia gibsoni in Vitro and in Vivo

    Zhai, Xiaohu / Li, Lingxu / Zhang, Peihao / Guo, Yiwen / Jiang, Huaide / He, Weihua / Li, Yanyan / Zhang, Bin / Yao, Dawei

    Journal of parasitology. 2022 July 25, v. 108, no. 4

    2022  

    Abstract: New antibabesial drugs are required to fight resistant parasites, and plant-derived natural products are a robust source. Six kinds of natural product extracts derived from herbal medicines that are traditionally used for the treatment of malaria were ... ...

    Abstract New antibabesial drugs are required to fight resistant parasites, and plant-derived natural products are a robust source. Six kinds of natural product extracts derived from herbal medicines that are traditionally used for the treatment of malaria were selected to test the antibabesial effect on Babesia gibsoni in vitro and in vivo. Parasitized blood was collected from dogs infected with B. gibsoni to evaluate the inhibitory effect of verbenalin, catechin hydrate, dihydrolycorine, embelin, ursolic acid, agrimol B, and bruceine H in vitro. The expression levels of the 18S rRNA gene in all drug-treated groups were determined by relative quantification using a real-time PCR method. Significant inhibition of the in vitro growth of B. gibsoni was observed after treatment by those natural product extracts (200 nM concentration) (P < 0.05). Catechin hydrate showed the highest activity in vitro due to the lowest expression levels of the 18S rRNA gene. The IC₅₀ value of catechin hydrate against B. gibsoni was 273 nM. In B. gibsoni infected dogs, intravenous administrations of catechin hydrate and diminazene aceturate showed significant (P < 0.05) inhibition of B. gibsoni growth at a dose of 11 mg/kg and 10 mg/kg, respectively, compared to the control group. The results of our study may suggest that catechin hydrate may be a promising alternative to treat canine babesiosis caused by B. gibsoni.
    Keywords Babesia gibsoni ; babesiosis ; blood ; catechin ; diminazene ; dogs ; genes ; intravenous injection ; malaria ; parasitism ; parasitology ; quantitative polymerase chain reaction ; ursolic acid
    Language English
    Dates of publication 2022-0725
    Size p. 301-305.
    Publishing place American Society of Parasitologists
    Document type Article
    ZDB-ID 300870-8
    ISSN 1937-2345 ; 0022-3395
    ISSN (online) 1937-2345
    ISSN 0022-3395
    DOI 10.1645/21-108
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 4' 49/56: Show issues

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  9. Article ; Online: Isotropic Hedgehog-Shaped-TiO

    Jiang, Huaide / He, Xiaoli / Ma, Yanmei / Fu, Bi / Xu, Xingui / Subramanian, Balachandran / Hu, Chengzhi

    ACS applied materials & interfaces

    2021  Volume 13, Issue 4, Page(s) 5406–5417

    Abstract: Directional motion in response to specific signals is critically important for micro/nanomotors in precise cargo transport, obstacle avoidance, collective control, and complex maneuvers. In this work, a kind of isotropic light-driven micromotor that is ... ...

    Abstract Directional motion in response to specific signals is critically important for micro/nanomotors in precise cargo transport, obstacle avoidance, collective control, and complex maneuvers. In this work, a kind of isotropic light-driven micromotor that is made of hedgehog-shaped TiO
    Language English
    Publishing date 2021-01-21
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.0c19606
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Dipole-Moment Induced Phototaxis and Fuel-Free Propulsion of ZnO/Pt Janus Micromotors.

    He, Xiaoli / Jiang, Huaide / Li, Jianjie / Ma, Yanmei / Fu, Bi / Hu, Chengzhi

    Small (Weinheim an der Bergstrasse, Germany)

    2021  Volume 17, Issue 31, Page(s) e2101388

    Abstract: Light-driven micromotors have stimulated considerate interests due to their potentials in biomedicine, environmental remediation, or serving as the model system for non-equilibrium physics of active matter. Simultaneous control over the motion direction ... ...

    Abstract Light-driven micromotors have stimulated considerate interests due to their potentials in biomedicine, environmental remediation, or serving as the model system for non-equilibrium physics of active matter. Simultaneous control over the motion direction and speed of micro/nanomotors is crucial for their functionality but still difficult since Brownian motion always randomizes the orientations. Here, a highly efficient light-driven ZnO/Pt Janus micromotor capable of aligning itself to illumination direction and exhibiting negative phototaxis at high speeds (up to 32 µm s
    MeSH term(s) Environmental Restoration and Remediation ; Phototaxis ; Zinc Oxide
    Chemical Substances Zinc Oxide (SOI2LOH54Z)
    Language English
    Publishing date 2021-06-25
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202101388
    Database MEDical Literature Analysis and Retrieval System OnLINE

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