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Article ; Online: Clinical effect of intestinal microecological therapy on gastrointestinal symptoms in patients with maintenance hemodialysis.

Qin, Xuexiang / Zheng, Chen / Jiang, Mengting

2023 Volume 46, Issue 12, Page(s) 5972–5973

MeSH term(s)	Humans ; Renal Dialysis ; Intestines
Language	English
Publishing date	2023-09-15
Publishing country	Netherlands
Document type	Letter
ZDB-ID	1068461-x
ISSN	0219-3108 ; 1015-9584
ISSN (online)	0219-3108
ISSN	1015-9584
DOI	10.1016/j.asjsur.2023.09.008
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Article ; Online: A data-based reduced-order model for dynamic simulation and control of district-heating networks

Jiang, Mengting / Speetjens, Michel / Rindt, Camilo / Smeulders, David

Applied Energy. 2023 June, v. 340 p.121038-

2023

Abstract: This study concerns the development of a data-based compact model for the prediction of the fluid temperature evolution in district heating (DH) pipeline networks. This so-called “reduced-order model” (ROM) is obtained from reduction of the conservation ... ...

Abstract	This study concerns the development of a data-based compact model for the prediction of the fluid temperature evolution in district heating (DH) pipeline networks. This so-called “reduced-order model” (ROM) is obtained from reduction of the conservation law for energy for each pipe segment to a semi-analytical input–output relation between the pipe outlet temperature and the pipe inlet and ground temperatures that can be identified from training data. The ROM basically is valid for generic pipe configurations involving 3D unsteady heat transfer and 3D steady flow as long as heat-transfer mechanisms are linearly dependent on the temperature field. Moreover, the training data can be generated by physics-based computational “full-order” models (FOMs) yet also by (calibration) experiments or field measurements. Performance tests using computational training data for a single-pipe configuration demonstrate that the ROM (i) can be successfully identified and (ii) can accurately describe the response of the outlet temperature to arbitrary input profiles for inlet and ground temperatures. Application of the ROM to two case studies, i.e. fast simulation of a small DH network and design of a controller for user-defined temperature regulation of a DH system, demonstrate its predictive ability and efficiency also for realistic systems. Dedicated cost analyses further reveal that the ROM may significantly reduce the computational costs compared to FOMs by (up to) orders of magnitude for higher-dimensional pipe configurations. These findings advance the proposed ROM as a robust and efficient simulation tool for practical DH systems with a far greater predictive ability than existing compact models.
Keywords	calibration ; energy ; heat transfer ; models ; prediction ; steady flow ; temperature ; District heating network ; Reduced-order model ; Input–output relation ; Linear time-invariant system
Language	English
Dates of publication	2023-06
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	2000772-3
ISSN	0306-2619
ISSN	0306-2619
DOI	10.1016/j.apenergy.2023.121038
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Modulating Driver Alertness via Ambient Olfactory Stimulation: A Wearable Electroencephalography Study.

Jiang, Mengting / Chaichanasittikarn, Oranatt / Seet, Manuel / Ng, Desmond / Vyas, Rahul / Saini, Gaurav / Dragomir, Andrei

Sensors (Basel, Switzerland)

2024 Volume 24, Issue 4

Abstract: Poor alertness levels and related changes in cognitive efficiency are common when performing monotonous tasks such as extended driving. Recent studies have investigated driver alertness decrement and possible strategies for modulating alertness with the ... ...

Abstract	Poor alertness levels and related changes in cognitive efficiency are common when performing monotonous tasks such as extended driving. Recent studies have investigated driver alertness decrement and possible strategies for modulating alertness with the goal of improving reaction times to safety critical events. However, most studies rely on subjective measures in assessing alertness changes, while the use of olfactory stimuli, which are known to be strong modulators of cognitive states, has not been commensurately explored in driving alertness settings. To address this gap, in the present study we investigated the effectiveness of olfactory stimuli in modulating the alertness state of drivers and explored the utility of electroencephalography (EEG) in developing objective brain-based tools for assessing the resulting changes in cortical activity. Olfactory stimulation induced a significant differential effect on braking reaction time. The corresponding effect to the cortical activity was characterized using EEG-derived metrics and the devised machine learning framework yielded a high discriminating accuracy (92.1%). Furthermore, neural activity in the alpha frequency band was found to be significantly associated with the observed drivers' behavioral changes. Overall, our results demonstrate the potential of olfactory stimuli to modulate the alertness state and the efficiency of EEG in objectively assessing the resulting cognitive changes.
MeSH term(s)	Automobile Driving/psychology ; Attention/physiology ; Reaction Time/physiology ; Electroencephalography/methods ; Wearable Electronic Devices
Language	English
Publishing date	2024-02-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s24041203
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Article: [Genetic diagnosis of a Chinese pedigree affected with Alazami syndrome].

He, Fengjuan / Xu, Shenjian / Li, Qiwen / Jiang, Mengting / Mao, Xiuzhen

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics

2022 Volume 39, Issue 10, Page(s) 1089–1092

Abstract: Objective: To explore the genetic etiology for a Chinese pedigree affected with Alazami syndrome.: Methods: Genomic DNA was extracted for 2 patients and 2 unaffected members from the pedigree. Whole exome sequencing was carried out to detect ... ...

Abstract	Objective: To explore the genetic etiology for a Chinese pedigree affected with Alazami syndrome. Methods: Genomic DNA was extracted for 2 patients and 2 unaffected members from the pedigree. Whole exome sequencing was carried out to detect potential variant in the proband, and the result was verified by Sanger sequencing. Results: The proband and her sister were both found to harbor compound heterozygous variants of LARP7 gene, namely c.94A>T (p.Lys32) and c.1141A>G (p.Lys381Glu), which were inherited from their father and mother, respectively. Both variants were predicted to be pathogenic based on bioinformatic analysis. Conclusion:* The two variants of the LARP7 gene, both were unreported previously, probably underlay the Alazami syndrome in this pedigree. Above finding has expanded the mutational spectrum of the LARP7 gene.
MeSH term(s)	China ; Dwarfism ; Female ; Humans ; Intellectual Disability/genetics ; Mutation ; Pedigree ; Ribonucleoproteins/genetics ; Whole Exome Sequencing
Chemical Substances	Larp7 protein, human ; Ribonucleoproteins
Language	Chinese
Publishing date	2022-09-30
Publishing country	China
Document type	Case Reports ; Journal Article
ISSN	1003-9406
ISSN	1003-9406
DOI	10.3760/cma.j.cn511374-20210909-00735
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Article: Clinical Characteristics of Coronavirus Disease 2019 (COVID-19): A Comparison Between Laboratory-Confirmed and Clinically Suspected Patients.

Li, Qi / Jiang, Meng-Ting / Yuan, Su-E

Iranian journal of science and technology. Transaction A, Science

2021 Volume 46, Issue 1, Page(s) 81–89

Abstract: To investigate the characteristic findings between laboratory-confirmed and clinically suspected patients with COVID-19. In this retrospective study, we included patients admitted to the Xiangya Hospital from Jan 24 to Feb 10, 2020. Two researchers ... ...

Abstract	To investigate the characteristic findings between laboratory-confirmed and clinically suspected patients with COVID-19. In this retrospective study, we included patients admitted to the Xiangya Hospital from Jan 24 to Feb 10, 2020. Two researchers separately collected and sorted out the patients' epidemiological, demographic, clinical, laboratory, and radiologic findings. SPSS was performed to analyze the collected data. 241 patients were admitted, including 28 (45.5; IQR, 34.0-52.5) confirmed and 213 (42.0; IQR, 30.0-57.0) suspected patients. The prevalence of COVID-19 disease in males was significantly higher than in females (64.3% vs. 35.7%,
Language	English
Publishing date	2021-11-15
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2444103-X
ISSN	1028-6276 ; 0360-1307
ISSN	1028-6276 ; 0360-1307
DOI	10.1007/s40995-021-01244-8
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Article: The effect of sex differences on neointimal characteristics of in-stent restenosis in drug-eluting stents: An optical coherence tomography study.

Yuan, Xiaohang / Jiang, Mengting / Feng, Huanhuan / Han, Yan / Zhang, Xi / Chen, Yundai / Gao, Lei

Heliyon

2023 Volume 9, Issue 8, Page(s) e19073

Abstract: Background: Previous studies have demonstrated that there are sex-related differences in atherosclerosis. However, in terms of the nature of in-stent restenosis (ISR) neointima, the effect of gender on the results is unclear.: Methods: Patients with ... ...

Abstract	Background: Previous studies have demonstrated that there are sex-related differences in atherosclerosis. However, in terms of the nature of in-stent restenosis (ISR) neointima, the effect of gender on the results is unclear. Methods: Patients with ISR of drug-eluting stents (DES) who underwent OCT examination in Senior Department of Cardiology of the Chinese People's Liberation Army General Hospital from March 2010 to March 2022 were included. The patients were divided into male and female groups. Results: In this study, a total of 230 DES-ISR patients and 249 DES-ISR target lesions were analyzed. OCT data showed that compared to females, males have a higher incidence of thin-cap fibrous atherosclerosis (TCFA) (37.4% [n = 77] vs. 9.3% [n = 4], p < 0.001) and in-stent neoatherosclerosis (ISNA) (82.0% [n = 169] vs. 62.8% [n = 27]). p = 0.005). In addition, a multivariate logistic regression analysis demonstrated that male was independently associated with a higher incidence of ISNA (OR: 2.659, 95% CI: 1.239-5.707; p = 0.012) and TCFA (OR: 4.216, 95% CI: 1.370-12.976; p = 0.012). Conclusion: For DES-ISR patients, the incidence of ISNA in female was significantly lower than that in male and vulnerability of neointimal pattern is lower in female than in male.
Language	English
Publishing date	2023-08-11
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e19073
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Article: Effect of perioperative acupoint electrical stimulation on macrophages in mice under operative stress.

Zhang, Yinzhou / Wei, Junying / Wu, Xinyuan / Jiang, Mengting / Ma, Wuhua / Li, Yuhui

Journal of inflammation (London, England)

2023 Volume 20, Issue 1, Page(s) 29

Abstract: The strong perioperative stress response caused by surgical anesthesia can significantly suppress immune function, and the body is in a state of immunosuppression for 3 to 4 days after surgery, which leads to an increase in the probability of ... ...

Abstract	The strong perioperative stress response caused by surgical anesthesia can significantly suppress immune function, and the body is in a state of immunosuppression for 3 to 4 days after surgery, which leads to an increase in the probability of postoperative infection. Traditional Chinese medicine believes that acupuncture points can "reconcile yin and yang", promote the recovery of immune function, and help reduce the incidence of postoperative infection. Macrophages are an important type of immune cells that participate in the body's innate immunity. They have powerful phagocytosis and clearance functions. They can be polarized into M1 and M2 types under the regulation of the body, and play different roles in fighting microbial infections. Among them, the M1 type can participate in the elimination of pathogens. In this study, we will investigate the perioperative acupoint electrical stimulation to alleviate the immunosuppressive state of surgical stress mice, clarify the regulation of perioperative acupoint electrical stimulation on glucocorticoids and the relationship between NF-κB molecules and macrophage polarization.The key molecules of related pathways were verified by glucocorticoid receptor inhibitors, and it was found that electrical stimulation of acupoints during the perioperative period can affect the polarization of macrophages in surgically stressed mice to the M1 type by reducing the level of glucocorticoids and promoting the expression of NF κB molecules. Further reveal the partial mechanism of electroacupuncture regulating the anti-inflammatory and pro-inflammatory processes of macrophages in the immune response.
Language	English
Publishing date	2023-08-30
Publishing country	England
Document type	Journal Article
ZDB-ID	2164385-4
ISSN	1476-9255
ISSN	1476-9255
DOI	10.1186/s12950-023-00354-x
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Article ; Online: Exploiting refractory organic matter for advanced nitrogen removal from mature landfill leachate via anammox in an expanded granular sludge bed reactor.

Jiang, Mengting / Ji, Shenghao / Wu, Ruixin / Yang, Huan / Li, Yu-You / Liu, Jianyong

Bioresource technology

2023 Volume 371, Page(s) 128594

Abstract: Anammox is an efficient low-carbon nitrogen removal technology for mature landfill leachate (MLL). However, it produces 11 % nitrate theoretically, which needs further removal. In this study, the mechanisms of exploiting refractory organic matter (ROM) ... ...

Abstract	Anammox is an efficient low-carbon nitrogen removal technology for mature landfill leachate (MLL). However, it produces 11 % nitrate theoretically, which needs further removal. In this study, the mechanisms of exploiting refractory organic matter (ROM) from an MLL as an inner carbon source for advanced nitrogen removal via anammox were systematically analyzed, and the effects of hydraulic retention time on nitrogen and ROM removal/utilization were investigated. Without any external carbon source, a total nitrogen and organic carbon removal efficiency of 94.50 % and 27.12 %, respectively, were achieved, with a nitrogen loading rate of 2.4 kg N/(m
MeSH term(s)	Denitrification ; Water Pollutants, Chemical ; Sewage ; Nitrogen ; Anaerobic Ammonia Oxidation ; Bioreactors ; Oxidation-Reduction
Chemical Substances	Water Pollutants, Chemical ; Sewage ; Nitrogen (N762921K75)
Language	English
Publishing date	2023-01-09
Publishing country	England
Document type	Journal Article
ZDB-ID	1065195-0
ISSN	1873-2976 ; 0960-8524
ISSN (online)	1873-2976
ISSN	0960-8524
DOI	10.1016/j.biortech.2023.128594
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Book ; Online: A reduced-order model for dynamic simulation of district heating networks

Jiang, Mengting / Speetjens, Michel / Rindt, Camilo / Smeulders, David

2022

Abstract: This study concerns the development of a data-based compact model for the prediction of the fluid temperature evolution in district heating (DH) pipeline networks. This so-called "reduced-order model" (ROM) is obtained from reduction of the conservation ... ...

Abstract	This study concerns the development of a data-based compact model for the prediction of the fluid temperature evolution in district heating (DH) pipeline networks. This so-called "reduced-order model" (ROM) is obtained from reduction of the conservation law for energy for each pipe segment to a semi-analytical input-output relation between the pipe outlet temperature and the pipe inlet and ground temperatures that can be identified from training data. The ROM basically is valid for generic pipe configurations involving 3D unsteady heat transfer and 3D steady flow as long as heat-transfer mechanisms are linearly dependent on the temperature field. Moreover, the training data can be generated by physics-based computational "full-order" models (FOMs) yet also by (calibration) experiments or field measurements. Performance tests using computational training data for a single 1D pipe configuration demonstrate that the ROM (i) can be successfully identified and (ii) can accurately describe the response of the outlet temperature to arbitrary input profiles for inlet and ground temperatures. Application of the ROM to two case studies, i.e. fast simulation of a small DH network and design of a controller for user-defined temperature regulation of a DH system, demonstrate its predictive ability and efficiency also for realistic systems. Dedicated cost analyses further reveal that the ROM may significantly reduce the computational costs compared to FOMs by (up to) orders of magnitude for higher-dimensional pipe configurations. These findings advance the proposed ROM as a robust and efficient simulation tool for practical DH systems with a far greater predictive ability than existing compact models. Comment: 30 pages, 19 figures
Keywords	Mathematics - Numerical Analysis
Subject code	621
Publishing date	2022-11-25
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Genetically proxied morning chronotype was associated with a reduced risk of prostate cancer.

Sun, Xiaohui / Ye, Ding / Jiang, Mengting / Qian, Yu / Mao, Yingying

Sleep

2021 Volume 44, Issue 10

Abstract: Study objectives: Observational epidemiological studies have suggested that chronotype may play a role in the pathogenesis and progression of prostate cancer. However, whether there is a causal association remains unknown. The aim of the present study ... ...

Abstract	Study objectives: Observational epidemiological studies have suggested that chronotype may play a role in the pathogenesis and progression of prostate cancer. However, whether there is a causal association remains unknown. The aim of the present study was to examine the potential causal relationship between chronotype and prostate cancer risk using a Mendelian randomization (MR) design. Methods: A total of 268 single nucleotide polymorphisms associated with chronotype were selected from a meta-analysis of genome-wide association studies of 697,828 individuals. The genetic association data for prostate cancer was derived from the Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome (PRACTICAL) Consortium (79,148 cases and 61,106 controls). Inverse-variance weighted (IVW) method was used as the primary analysis to calculate the causal effect estimates. The weighted-median method, MR-Egger regression, MR-Pleiotropy Residual Sum and Outlier (MR-PRESSO) test, and multivariable MR analyses were applied as sensitivity analysis. Results: Genetically predicted morningness (scaled to a sleep midpoint of 1 h earlier) had a reduced risk of prostate cancer, with an odds ratio of 0.71 (95% confidence interval [CI]: 0.54-0.94 by IVW), compared with the eveningness. Similar causal effect estimates were also observed by using the weighted median and MR-PRESSO analyses. In addition, results from the multivariable MR analysis supported the findings from the univariable MR analyses. No indication of horizontal pleiotropy was observed in the MR-Egger analysis (p for intercept = 0.234). Conclusion: Our findings provide evidence of a causal protective effect of morning chronotype on the risk of prostate cancer.
MeSH term(s)	Genome-Wide Association Study ; Humans ; Male ; Mendelian Randomization Analysis ; Polymorphism, Single Nucleotide/genetics ; Prostatic Neoplasms/epidemiology ; Prostatic Neoplasms/genetics ; Sleep
Language	English
Publishing date	2021-04-20
Publishing country	United States
Document type	Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't
ZDB-ID	424441-2
ISSN	1550-9109 ; 0161-8105
ISSN (online)	1550-9109
ISSN	0161-8105
DOI	10.1093/sleep/zsab104
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