LIVIVO - Search results -

Search results

Result 1 - 10 of total 275

Search options

Book ; Online ; E-Book: New techniques for studying biomembranes

Jiang, Qiu-Xing

(Methods in signal transduction)

2020

Author's details	edited by Qiu-Xing Jiang
Series title	Methods in signal transduction
Keywords	Membranes (Biology) ; MEDICAL ; Biotechnology ; SCIENCE ; Life Sciences ; Cytology ; SCIENCE ; Life Sciences ; Biology ; Molecular Biology
Language	English
Size	1 Online-Ressource (xv, 164 Seiten), Illustrationen, Diagramme
Edition	First edition
Publisher	CRC Press, Taylor & Francis Group
Publishing place	Boca Raton
Publishing country	United States
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
HBZ-ID	HT020482320
ISBN	978-0-429-86654-8 ; 978-0-429-46138-5 ; 9781138618060 ; 0-429-86654-2 ; 0-429-46138-0 ; 1138618063
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

Full text online

Accessible to users with ZB MED library card

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- Full text online
- Order with fees

Article ; Online: Research progress on invasive cervical resorption

LIU Qiuping / JIANG Qiu

口腔疾病防治, Vol 32, Iss 1, Pp 70-

2024 Volume 75

Abstract: Tooth absorption can be divided into physiological absorption and pathological absorption. Root absorption of mature deciduous teeth is physiological absorption. Pathological absorption includes internal absorption and external absorption. Internal ... ...

Abstract	Tooth absorption can be divided into physiological absorption and pathological absorption. Root absorption of mature deciduous teeth is physiological absorption. Pathological absorption includes internal absorption and external absorption. Internal absorption, also known as intramedullary absorption, includes inflammatory absorption and alternative absorption. External tooth absorption originates from the outer surface of the root or the neck of the tooth and can be divided into inflammatory absorption, alternative absorption, pressure resorption and invasive cervical resorption. Invasive cervical resorption (ICR) is pathological damage caused by many factors, which usually begins in the cemento-enamel junction and extends peripherally or horizontally in the dentin. It hardly invades the pulp. Orthodontic devices, trauma, bleaching, systemic diseases, and the use of certain medications can all lead to invasive cervical resorption. The clinical manifestations of ICR are usually asymptomatic or not obvious, and most of which are found in imaging examinations. Because caries and internal absorption are often misdiagnosed through plain apical radiography, cone beam computed tomography (CBCT) can help to better understand the situation of invasive cervical resorption. Because the pathogenesis and etiology of invasive cervical resorption are not fully understood, clinical negligence and inadequate treatment of invasive cervical resorption can even cause unnecessary tooth loss. This article reviews the latest research progress on the histopathologic features, pathogenic mechanism, susceptibility factors, diagnosis and treatment of ICR, with special emphasis on susceptibility factors and their mechanisms.
Keywords	tooth resorption， ; invasive cervical resorption， ; receptor activator of nuclear factor， ; osteoprotegerin， ; inflammatory factor， ; multiple idiopathic external cervical root resorption， ; susceptibility factors， ; cone beam ct， ; Medicine ; R
Subject code	610
Language	Chinese
Publishing date	2024-01-01T00:00:00Z
Publisher	Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio: Markers predicting immune-checkpoint inhibitor efficacy and immune-related adverse events.

Jiang, Qiu-Yu / Xue, Ru-Yi

World journal of gastrointestinal oncology

2024 Volume 16, Issue 3, Page(s) 577–582

Abstract: We conducted a comprehensive review of existing prediction models pertaining to the efficacy of immune-checkpoint inhibitor (ICI) and the occurrence of immune-related adverse events (irAEs). The predictive potential of neutrophil-to-lymphocyte ratio (NLR) ...

Abstract	We conducted a comprehensive review of existing prediction models pertaining to the efficacy of immune-checkpoint inhibitor (ICI) and the occurrence of immune-related adverse events (irAEs). The predictive potential of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in determining ICI effectiveness has been extensively investigated, while limited research has been conducted on predicting irAEs. Furthermore, the combined model incorporating NLR and PLR, either with each other or in conjunction with additional markers such as carcinoembryonic antigen, exhibits superior predictive capabilities compared to individual markers alone. NLR and PLR are promising markers for clinical applications. Forthcoming models ought to incorporate established efficacious models and newly identified ones, thereby constituting a multifactor composite model. Furthermore, efforts should be made to explore effective clinical application approaches that enhance the predictive accuracy and efficiency.
Language	English
Publishing date	2024-04-03
Publishing country	China
Document type	Editorial
ZDB-ID	2573696-6
ISSN	1948-5204
ISSN	1948-5204
DOI	10.4251/wjgo.v16.i3.577
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Research progress on ankylosis of primary molars

DONG Ning / JIANG Qiu

口腔疾病防治, Vol 31, Iss 5, Pp 370-

2023 Volume 374

Abstract: Ankylosis of primary molars is a kind of eruption abnormality of the teeth, where the periodontal membrane disappears, owing to a bony union between bone and root. Studies have shown that the common proportion of ankylosed primary molars is 1.3%~8.9% ... ...

Abstract	Ankylosis of primary molars is a kind of eruption abnormality of the teeth, where the periodontal membrane disappears, owing to a bony union between bone and root. Studies have shown that the common proportion of ankylosed primary molars is 1.3%~8.9% with an equal occurrence. In the primary dentition, the mandibular first primary molar is the most commonly affected tooth, while in the middle mixed dentition stage of development, the second primary molar is more affected. Its etiology may be related to genetics, signaling pathways of mineralization metabolism of local alveolar bone or cementum, cytokines secreted by epithelial rest cells of Malassez, and enhanced inflammatory reactions during physiological absorption of roots. Ankylosis of primary molars can be diagnosed by clinical symptoms and imaging and is classified as mild, moderate and severe according to the degree of infraocclusion. As it may cause a series of complications, such as occlusal disturbances, delayed exfoliation and incomplete alveolar process development, multidisciplinary treatment, including in the departments of pediatric dentistry, orthodontics, periodontics and prosthodontics, should be adopted, and long-term treatment is determined based on the patient's age, severity of infraocclusion, and presence of permanent teeth. This review summarizes the etiology, diagnosis, complications and treatment of ankylosed primary molars to provide a reference for the clinical diagnosis and treatment of decidual molar fixation.
Keywords	tooth ankylosis ; primary molar ; infraocclusion ; human periodontal ligament cells ; dental developmental anomalies ; wnt signaling pathway ; epithelial cell rests of malassez ; receptor activator for nuclear factor-κb ligand ; Medicine ; R
Subject code	610
Language	Chinese
Publishing date	2023-05-01T00:00:00Z
Publisher	Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: High-Resolution Structures of K

Jiang, Qiu-Xing

Handbook of experimental pharmacology

2021 Volume 267, Page(s) 51–81

Abstract: Potassium channels are present in every living cell and essential to setting up a stable, non-zero transmembrane electrostatic potential which manifests the off-equilibrium livelihood of the cell. They are involved in other cellular activities and ... ...

Abstract	Potassium channels are present in every living cell and essential to setting up a stable, non-zero transmembrane electrostatic potential which manifests the off-equilibrium livelihood of the cell. They are involved in other cellular activities and regulation, such as the controlled release of hormones, the activation of T-cells for immune response, the firing of action potential in muscle cells and neurons, etc. Pharmacological reagents targeting potassium channels are important for treating various human diseases linked to dysfunction of the channels. High-resolution structures of these channels are very useful tools for delineating the detailed chemical basis underlying channel functions and for structure-based design and optimization of their pharmacological and pharmaceutical agents. Structural studies of potassium channels have revolutionized biophysical understandings of key concepts in the field - ion selectivity, conduction, channel gating, and modulation, making them multi-modality targets of pharmacological regulation. In this chapter, I will select a few high-resolution structures to illustrate key structural insights, proposed allostery behind channel functions, disagreements still open to debate, and channel-lipid interactions and co-evolution. The known structural consensus allows the inference of conserved molecular mechanisms shared among subfamilies of K
MeSH term(s)	Action Potentials ; Humans ; Ion Channel Gating ; Membrane Potentials ; Potassium Channels ; Structure-Activity Relationship
Chemical Substances	Potassium Channels
Language	English
Publishing date	2021-04-09
Publishing country	Germany
Document type	Journal Article
ISSN	0171-2004
ISSN	0171-2004
DOI	10.1007/164_2021_454
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Sign. bis Bd. 125 (1997): 1982 A 2146: Show issues
danach: Sign. bei den Einzelbänden: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Single-Run Catalysis and Kinetic Control of Human Telomerase Holoenzyme.

Jiang, Qiu-Xing

Advances in experimental medicine and biology

2021 Volume 1371, Page(s) 109–129

Abstract: Genome stability in eukaryotic cells relies on proper maintenance of telomeres at the termini of linear chromosomes. Human telomerase holoenzyme is required for maintaining telomere stability in a majority of proliferative human cells, making it ... ...

Abstract	Genome stability in eukaryotic cells relies on proper maintenance of telomeres at the termini of linear chromosomes. Human telomerase holoenzyme is required for maintaining telomere stability in a majority of proliferative human cells, making it essential for control of cell division and aging, stem cell maintenance, and development and survival of tumor or cancer. A dividing human cell usually contains a limited number of active telomerase holoenzymes. Recently, we discovered that a human telomerase catalytic site undergoes catalysis-dependent shut-off and an inactive site can be reactivated by cellular fractions containing human intracellular telomerase-activating factors (hiTAFs). Such ON-OFF control of human telomerase activity suggests a dynamic switch between inactive and active pools of the holoenzymes. In this review, we will link the ON-OFF control to the thermodynamic and kinetic properties of human telomerase holoenzymes, and discuss its potential contributions to the maintenance of telomere length equilibrium. This treatment suggests probabilistic fluctuations in the number of active telomerase holoenzymes as well as the number of telomeres that are extended in a limited number of cell cycles, and may be an important component of a fully quantitative model for the dynamic control of telomerase activities and telomere lengths in different types of eukaryotic cells.
MeSH term(s)	Aging ; Catalysis ; Holoenzymes/genetics ; Holoenzymes/metabolism ; Humans ; Telomerase/genetics ; Telomere/genetics ; Telomere/metabolism
Chemical Substances	Holoenzymes ; Telomerase (EC 2.7.7.49)
Language	English
Publishing date	2021-12-28
Publishing country	United States
Document type	Journal Article ; Review
ISSN	2214-8019 ; 0065-2598
ISSN (online)	2214-8019
ISSN	0065-2598
DOI	10.1007/5584_2021_676
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Embryonic expression patterns of TBL1 family in zebrafish.

Jia, Yuanqi / Jiang, Qiu / Sun, Shuna

Gene expression patterns : GEP

2024 Volume 51, Page(s) 119355

Abstract: Except the addition of TBL1Y in human, transducing beta like 1 (TBL1) family mainly consists of two members TBL1X and TBL1XR1, taking part in multiple intracellular signaling pathways such as Wnt/β-catenin and NF-κB in cancer progression. However, the ... ...

Abstract	Except the addition of TBL1Y in human, transducing beta like 1 (TBL1) family mainly consists of two members TBL1X and TBL1XR1, taking part in multiple intracellular signaling pathways such as Wnt/β-catenin and NF-κB in cancer progression. However, the gene expression patterns of this family during embryonic development remain largely unknown. Here we took advantage of zebrafish model to characterize the spatial and temporal expression patterns of TBL1 family genes including tbl1x, tbl1xr1a and tbl1xr1b. The in situ hybridization studies of gene expression showed robust expressions of tbl1x and tbl1xr1b as maternal transcripts except tbl1xr1a. As the embryo develops, zygotic expressions of all TBL1 family members occur and have a redundant and broad pattern including in brain, neural retina, pharyngeal arches, otic vesicles, and pectoral fins. Ubiquitous expression of all family members were ranked from the strongest to the weakest: tbl1xr1a, tbl1x, and tbl1xr1b. In addition, one tbl1xr1a transcript tbl1xr1a202 showed unique and rich expression in the developing heart and lateral line neuromasts. Overall, all members of zebrafish TBL1 family shared numerous similarities and exhibited certain distinctions in the expression patterns, indicating that they might have redundant and exclusive functions to be further explored.
MeSH term(s)	Animals ; Signal Transduction ; Transducin/genetics ; Transducin/metabolism ; Zebrafish ; Zebrafish Proteins/genetics ; Zebrafish Proteins/metabolism
Chemical Substances	Transducin (EC 3.6.5.1) ; Zebrafish Proteins
Language	English
Publishing date	2024-01-23
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2058346-1
ISSN	1872-7298 ; 1567-133X
ISSN (online)	1872-7298
ISSN	1567-133X
DOI	10.1016/j.gep.2024.119355
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 5515: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Optimizing the spatial pattern of the cold island to mitigate the urban heat island effect

Jiang Qiu / Xiaoyu Li / Wenqi Qian

Ecological Indicators, Vol 154, Iss , Pp 110550- (2023)

2023

Abstract: Numerous studies on reducing the urban heat island effect have concentrated on isolated cold islands, analyzing their cooling impact in terms of size and shape. From an international perspective, studies have shown that enhancing the connectivity of cold ...

Abstract	Numerous studies on reducing the urban heat island effect have concentrated on isolated cold islands, analyzing their cooling impact in terms of size and shape. From an international perspective, studies have shown that enhancing the connectivity of cold islands can enhance the cooling effect of cold islands, but they do not suggest specific processes and ideas for cold island connectivity. This study aims to investigate how to connect cold islands to optimize the spatial pattern of the cold island. Therefore, a cold island connectivity framework is constructed in this study: cooling source area - cooling network. Firstly, the core area of the cold island was identified by the morphological spatial pattern analysis. Then, connectivity analysis was applied to identify the cooling sources. Afterward, a minimum cumulative resistance model is used to construct the cooling network. In Nanjing, for case in point, the results reveal that a total of 27 cooling source areas and 52 cooling corridors have been identified. 6 first-level CSAs situated in the northern suburbs of Nanjing prevent the spread of the urban heat island effect. 2 second-level CSAs and 18 third-level CSAs are scattered throughout Nanjing to improve the urban climate. The 29 primary corridors help to mitigate heat transfer from the city center. The 23 secondary corridors are mainly located in urban centers contributing to preventing heat island from aggregating. The framework can be used as a strategic measure to prevent the fragmentation and isolation of the cold island, which provides implications for preventing the further expansion of urban heat island.
Keywords	Urban heat island ; Cold island ; Connectivity ; Cooling source area ; Cooling network ; Ecology ; QH540-549.5
Subject code	910
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Book ; Thesis: Treatment of two patients with Herlitz junctional epidermolysis bullosa with artificial skin bioequivalents

Jiang, Qiu-Jie

2002

Author's details	vorgelegt von Qui-Jie Jiang
Language	English
Size	35 Bl., Ill., graph. Darst.
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Erlangen, Nürnberg, Univ., Diss., 2003
Note	Enth. 1 Sonderabdr. aus: The journal of pediatrics ; Vol. 141. 2002
HBZ-ID	HT013742506
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
2003 E 2410	order for loan	Magazin

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Insights into carbon-fixation pathways through metagonomics in the sediments of deep-sea cold seeps.

Jiang, QiuYun / Jing, Hongmei / Jiang, QiuLong / Zhang, Yue

Marine pollution bulletin

2022 Volume 176, Page(s) 113458

Abstract: Carbon fixation by chemoautotrophic microorganisms in the dark ocean has a major impact on global carbon cycling and ecological relationships in the ocean's interior. At present, six pathways of autotrophic carbon fixation have been found: the Calvin ... ...

Abstract	Carbon fixation by chemoautotrophic microorganisms in the dark ocean has a major impact on global carbon cycling and ecological relationships in the ocean's interior. At present, six pathways of autotrophic carbon fixation have been found: the Calvin cycle, the reductive Acetyl-CoA or Wood-Ljungdahl pathway (rAcCoA), the reductive tricarboxylic acid cycle (rTCA), the 3-hydroxypropionate bicycle (3HP), the 3-hydroxypropionate/4-hydroxybutyrate cycle (3HP/4HB), and the dicarboxylate/4-hydroxybutyrate cycle (DC/4HB). Although our knowledge about carbon fixation pathways in the ocean has increased significantly, carbon fixation pathways in the cold seeps are still unknown. In this study, we collected sediment samples from two cold seeps and one trough in the south China sea (SCS), and investigated with metagenomic and metagenome assembled genomes (MAGs). We found that six autotrophic carbon fixation pathways present in the cold seeps and trough with rTCA cycle was the most common pathway, whose genes were particularly high in the cold seeps and increased with sediment depths; the rAcCoA cycle mainly occurred in the cold seep regions, and the abundance of module genes increased with sediment depths. We also elucidated members of chemoautotrophic microorganisms involved in these six carbon-fixation pathways. The rAcCoA, rTCA and DC/4-HB cycles required significantly less energy probably play an important role in the deep-sea environments, especially in the cold seeps. This study provided metabolic insights into the carbon fixation pathways in the cold seeps, and laid the foundation for future detailed study on processes and rates of carbon fixation in the deep-sea ecosystems.
MeSH term(s)	Carbon/metabolism ; Carbon Cycle ; Ecosystem ; Metagenome ; Phylogeny
Chemical Substances	Carbon (7440-44-0)
Language	English
Publishing date	2022-02-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2001296-2
ISSN	1879-3363 ; 0025-326X
ISSN (online)	1879-3363
ISSN	0025-326X
DOI	10.1016/j.marpolbul.2022.113458
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

To top

Full text online

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito